"Cyclin D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin subtype that is specific for CYCLIN-DEPENDENT KINASE 4 and CYCLIN-DEPENDENT KINASE 6. Unlike most cyclins, cyclin D expression is not cyclical, but rather it is expressed in response to proliferative signals. Cyclin D may therefore play a role in cellular responses to mitogenic signals.
| Descriptor ID |
D056741
|
| MeSH Number(s) |
D12.644.360.262.150 D12.776.167.218.150 D12.776.476.262.150
|
| Concept/Terms |
Cyclin D- Cyclin D
- Type D Cyclins
- Cyclins, Type D
- D Cyclins, Type
- Type D Cyclin
- Cyclin, Type D
- D Cyclin, Type
|
Below are MeSH descriptors whose meaning is more general than "Cyclin D".
Below are MeSH descriptors whose meaning is more specific than "Cyclin D".
This graph shows the total number of publications written about "Cyclin D" by people in this website by year, and whether "Cyclin D" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclin D" by people in Profiles.
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Palbociclib in Solid Tumor Patients With Genomic Alterations in the cyclinD-cdk4/6-INK4a-Rb Pathway: Results From National Cancer Institute-Children's Oncology Group Pediatric Molecular Analysis for Therapy Choice Trial Arm I (APEC1621I). JCO Precis Oncol. 2024 Sep; 8:e2400418.
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Tamoxifen suppresses pancreatic ?-cell proliferation in mice. PLoS One. 2019; 14(9):e0214829.
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Effects of alginate oligomer on the expression of cell cycle- and stress-related genes in Chlamydomonas reinhardtii. Biosci Biotechnol Biochem. 2017 Jun; 81(6):1254-1260.
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Recruitment of trimeric proliferating cell nuclear antigen by G1-phase cyclin-dependent kinases following DNA damage with platinum-based antitumour agents. Br J Cancer. 2013 Oct 29; 109(9):2378-88.
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Evidence for the ubiquitin protease UBP43 as an antineoplastic target. Mol Cancer Ther. 2012 Sep; 11(9):1968-77.
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NF-kappaB2/p52 enhances androgen-independent growth of human LNCaP cells via protection from apoptotic cell death and cell cycle arrest induced by androgen-deprivation. Prostate. 2008 Dec 01; 68(16):1725-33.
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The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice. Br J Cancer. 2008 Apr 22; 98(8):1380-8.
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Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G1-S transition. Oncogene. 2008 May 15; 27(22):3176-85.
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Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure. J Clin Invest. 2007 Sep; 117(9):2431-44.
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Mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland. J Biol Chem. 2007 Oct 26; 282(43):31766-76.