Calcium-Calmodulin-Dependent Protein Kinase Kinase
"Calcium-Calmodulin-Dependent Protein Kinase Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A regulatory calcium-calmodulin-dependent protein kinase that specifically phosphorylates CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 4; and PROTEIN KINASE B. It is a monomeric enzyme that is encoded by at least two different genes.
| Descriptor ID |
D054737
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.125.049 D12.644.360.100.049 D12.776.476.100.049
|
| Concept/Terms |
Calcium-Calmodulin-Dependent Protein Kinase Kinase- Calcium-Calmodulin-Dependent Protein Kinase Kinase
- Calcium Calmodulin Dependent Protein Kinase Kinase
- Calcium-Calmodulin-Dependent Protein Kinase I Activator
- Calcium Calmodulin Dependent Protein Kinase I Activator
- Calcium-Calmodulin-Dependent Kinase Kinase
- Calcium Calmodulin Dependent Kinase Kinase
- CaMKK
- CaM-KK
- CaM Kinase I Activator
Calcium-Calmodulin-Dependent Protein Kinase Kinase 2- Calcium-Calmodulin-Dependent Protein Kinase Kinase 2
- Calcium Calmodulin Dependent Protein Kinase Kinase 2
- CaMKKbeta
- Calcium-Calmodulin-Dependent Protein Kinase Kinase beta
- Calcium Calmodulin Dependent Protein Kinase Kinase beta
- CaM-Kinase Kinase beta
- CaM Kinase Kinase beta
- CamKK-beta
Calcium-Calmodulin-Dependent Protein Kinase Kinase 1- Calcium-Calmodulin-Dependent Protein Kinase Kinase 1
- Calcium Calmodulin Dependent Protein Kinase Kinase 1
- CaMKKalpha
- Calcium-Calmodulin-Dependent Protein Kinase Kinase alpha
- Calcium Calmodulin Dependent Protein Kinase Kinase alpha
- CaM-Kinase Kinase alpha
- CaM Kinase Kinase alpha
- CamKK-alpha
- CamKK alpha
|
Below are MeSH descriptors whose meaning is more general than "Calcium-Calmodulin-Dependent Protein Kinase Kinase".
Below are MeSH descriptors whose meaning is more specific than "Calcium-Calmodulin-Dependent Protein Kinase Kinase".
This graph shows the total number of publications written about "Calcium-Calmodulin-Dependent Protein Kinase Kinase" by people in this website by year, and whether "Calcium-Calmodulin-Dependent Protein Kinase Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 4 | 0 | 4 |
| 2012 | 4 | 0 | 4 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Calcium-Calmodulin-Dependent Protein Kinase Kinase" by people in Profiles.
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CaMKK2: bridging the gap between Ca2+ signaling and energy-sensing. Essays Biochem. 2024 Nov 18; 68(3):309-320.
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Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity. Cancer Res. 2024 03 04; 84(5):703-724.
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CaMKK2 as an emerging treatment target for bipolar disorder. Mol Psychiatry. 2023 Nov; 28(11):4500-4511.
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Increased CaMKK2 Expression Is an Adaptive Response That Maintains the Fitness of Tumor-Infiltrating Natural Killer Cells. Cancer Immunol Res. 2023 01 03; 11(1):109-122.
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Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer. Cells. 2022 06 10; 11(12).
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Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism. Mol Metab. 2022 08; 62:101513.
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Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling. Oncogene. 2021 03; 40(9):1690-1705.
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Spatial control of AMPK signaling at subcellular compartments. Crit Rev Biochem Mol Biol. 2020 02; 55(1):17-32.
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TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKK?/VPS34 pathway. Nat Commun. 2019 12 10; 10(1):5630.
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CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer. Nat Commun. 2019 06 04; 10(1):2450.