"Cyclin T" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin subtype that is found associated with CYCLIN-DEPENDENT KINASE 9. Unlike traditional cyclins, which regulate the CELL CYCLE, type T cyclins appear to regulate transcription and are components of positive transcriptional elongation factor B.
| Descriptor ID |
D056906
|
| MeSH Number(s) |
D12.644.360.262.700 D12.776.167.218.700 D12.776.476.262.700 D12.776.930.955.500.249
|
| Concept/Terms |
Cyclin T- Cyclin T
- Type T Cyclin
- Cyclin, Type T
- Type T Cyclins
- Cyclins, Type T
|
Below are MeSH descriptors whose meaning is more general than "Cyclin T".
Below are MeSH descriptors whose meaning is more specific than "Cyclin T".
This graph shows the total number of publications written about "Cyclin T" by people in this website by year, and whether "Cyclin T" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 4 | 4 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclin T" by people in Profiles.
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Smoking Modifies Pancreatic Cancer Risk Loci on 2q21.3. Cancer Res. 2021 06 01; 81(11):3134-3143.
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Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells. Virol J. 2019 02 20; 16(1):22.
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The HIV-1 Tat Protein: Mechanism of Action and Target for HIV-1 Cure Strategies. Curr Pharm Des. 2017; 23(28):4098-4102.
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Short Communication: The Broad-Spectrum Histone Deacetylase Inhibitors Vorinostat and Panobinostat Activate Latent HIV in CD4(+) T Cells In Part Through Phosphorylation of the T-Loop of the CDK9 Subunit of P-TEFb. AIDS Res Hum Retroviruses. 2016 Feb; 32(2):169-73.
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FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency. J Biol Chem. 2015 Nov 06; 290(45):27297-27310.
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Subversion of Cell Cycle Regulatory Mechanisms by HIV. Cell Host Microbe. 2015 Jun 10; 17(6):736-40.
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Short communication: SAHA (vorinostat) induces CDK9 Thr-186 (T-loop) phosphorylation in resting CD4+ T cells: implications for reactivation of latent HIV. AIDS Res Hum Retroviruses. 2015 Jan; 31(1):137-41.
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Targeting SQSTM1/p62 induces cargo loading failure and converts autophagy to apoptosis via NBK/Bik. Mol Cell Biol. 2014 Sep 15; 34(18):3435-49.
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Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells. J Virol. 2013 Jan; 87(2):1211-20.
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Identification of novel CDK9 and Cyclin T1-associated protein complexes (CCAPs) whose siRNA depletion enhances HIV-1 Tat function. Retrovirology. 2012 Oct 30; 9:90.