"Virus Latency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ability of a pathogenic virus to lie dormant within a cell (latent infection). In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. Latency in bacteriophage is maintained by the expression of virally encoded repressors.
| Descriptor ID |
D017735
|
| MeSH Number(s) |
G06.920.900
|
| Concept/Terms |
Virus Latency- Virus Latency
- Latencies, Virus
- Latency, Virus
- Virus Latencies
- Viral Latency
- Latencies, Viral
- Latency, Viral
- Viral Latencies
|
Below are MeSH descriptors whose meaning is more general than "Virus Latency".
Below are MeSH descriptors whose meaning is more specific than "Virus Latency".
This graph shows the total number of publications written about "Virus Latency" by people in this website by year, and whether "Virus Latency" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 3 | 3 |
| 2016 | 1 | 1 | 2 |
| 2017 | 3 | 1 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Virus Latency" by people in Profiles.
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Cotargeting EBV lytic as well as latent cycle antigens increases T-cell potency against lymphoma. Blood Adv. 2024 07 09; 8(13):3360-3371.
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Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models. mBio. 2024 Feb 14; 15(2):e0299823.
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Latent human herpesvirus 6 is reactivated in CAR T cells. Nature. 2023 Nov; 623(7987):608-615.
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m6A Regulates the Stability of Cellular Transcripts Required for Efficient KSHV Lytic Replication. Viruses. 2023 06 16; 15(6).
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Clearance of HIV-1 or SIV reservoirs by promotion of apoptosis and inhibition of autophagy: Targeting intracellular molecules in cure-directed strategies. J Leukoc Biol. 2022 11; 112(5):1245-1259.
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Impact of Anti-PD-1 and Anti-CTLA-4 on the Human Immunodeficiency Virus (HIV) Reservoir in People Living With HIV With Cancer on Antiretroviral Therapy: The AIDS Malignancy Consortium 095 Study. Clin Infect Dis. 2021 10 05; 73(7):e1973-e1981.
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The Combination of Venetoclax and Ixazomib Selectively and Efficiently Kills HIV-Infected Cell Lines but Has Unacceptable Toxicity in Primary Cell Models. J Virol. 2021 05 24; 95(12).
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Identification of celastrol as a novel HIV-1 latency reversal agent by an image-based screen. PLoS One. 2021; 16(4):e0244771.
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Herpes Simplex Virus 1 MicroRNA miR-H8 Is Dispensable for Latency and Reactivation In Vivo. J Virol. 2021 01 28; 95(4).
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Dangerous Liaisons: Gammaherpesvirus Subversion of the Immunoglobulin Repertoire. Viruses. 2020 07 23; 12(8).