"Cyclin E" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 50-kDa protein that complexes with CYCLIN-DEPENDENT KINASE 2 in the late G1 phase of the cell cycle.
| Descriptor ID |
D019927
|
| MeSH Number(s) |
D12.644.360.262.180 D12.776.167.218.180 D12.776.476.262.180
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cyclin E".
Below are MeSH descriptors whose meaning is more specific than "Cyclin E".
This graph shows the total number of publications written about "Cyclin E" by people in this website by year, and whether "Cyclin E" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 3 | 4 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cyclin E" by people in Profiles.
-
Pervasive chromosomal instability and karyotype order in tumour evolution. Nature. 2020 11; 587(7832):126-132.
-
CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers. Nat Commun. 2017 06 27; 8:15916.
-
Suppression of Akt-mTOR pathway-a novel component of oncogene induced DNA damage response barrier in breast tumorigenesis. PLoS One. 2014; 9(5):e97076.
-
A non-redundant function of cyclin E1 in hematopoietic stem cells. Cell Cycle. 2013 Dec 01; 12(23):3663-72.
-
Addition of rituximab to chemotherapy overcomes the negative prognostic impact of cyclin E expression in diffuse large B-cell lymphoma. J Clin Pathol. 2013 Nov; 66(11):956-61.
-
Ursolic acid enhances mouse liver regeneration after partial hepatectomy. Pharm Biol. 2012 Apr; 50(4):523-8.
-
Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway. Mol Cancer. 2010 Sep 21; 9:253.
-
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Proc Natl Acad Sci U S A. 2010 Jul 27; 107(30):13390-5.
-
A cancer-derived mutation in the PSTAIRE helix of cyclin-dependent kinase 2 alters the stability of cyclin binding. Biochim Biophys Acta. 2010 Jul; 1803(7):858-64.
-
FoxM1B regulates NEDD4-1 expression, leading to cellular transformation and full malignant phenotype in immortalized human astrocytes. Cancer Res. 2010 Apr 01; 70(7):2951-61.