"Cyclin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin subtype that has specificity for CDC2 PROTEIN KINASE and CYCLIN-DEPENDENT KINASE 2. It plays a role in progression of the CELL CYCLE through G1/S and G2/M phase transitions.
| Descriptor ID |
D019925
|
| MeSH Number(s) |
D12.644.360.262.100 D12.776.167.218.100 D12.776.476.262.100
|
| Concept/Terms |
Cyclin A- Cyclin A
- Type A Cyclin
- Cyclin, Type A
- Type A Cyclins
- Cyclins, Type A
- Adenovirus E1A-Associated Protein p60
- Adenovirus E1A Associated Protein p60
- E1A p60
|
Below are MeSH descriptors whose meaning is more general than "Cyclin A".
Below are MeSH descriptors whose meaning is more specific than "Cyclin A".
This graph shows the total number of publications written about "Cyclin A" by people in this website by year, and whether "Cyclin A" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 4 | 5 |
| 2003 | 1 | 3 | 4 |
| 2004 | 1 | 3 | 4 |
| 2005 | 2 | 2 | 4 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 2 | 3 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2013 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclin A" by people in Profiles.
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Effects of alginate oligomer on the expression of cell cycle- and stress-related genes in Chlamydomonas reinhardtii. Biosci Biotechnol Biochem. 2017 Jun; 81(6):1254-1260.
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Elevated cyclin A associated kinase activity promotes sensitivity of metastatic human cancer cells to DNA antimetabolite drug. Int J Oncol. 2015 Aug; 47(2):782-90.
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Arginine methylation-dependent reader-writer interplay governs growth control by E2F-1. Mol Cell. 2013 Oct 10; 52(1):37-51.
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New structural insights into phosphorylation-free mechanism for full cyclin-dependent kinase (CDK)-cyclin activity and substrate recognition. J Biol Chem. 2013 Oct 18; 288(42):30682-30692.
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TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73. Mol Cell Biol. 2011 Nov; 31(22):4464-81.
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Mesothelin confers pancreatic cancer cell resistance to TNF-a-induced apoptosis through Akt/PI3K/NF-?B activation and IL-6/Mcl-1 overexpression. Mol Cancer. 2011 Aug 31; 10:106.
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Partial agonist activity of the progesterone receptor antagonist RU486 mediated by an amino-terminal domain coactivator and phosphorylation of serine400. Mol Endocrinol. 2010 Feb; 24(2):335-45.
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Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells. Mol Cell Biol. 2009 Feb; 29(3):758-70.
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Immunohistochemical and biogenetic features of diffuse-type tenosynovial giant cell tumors: the potential roles of cyclin A, P53, and deletion of 15q in sarcomatous transformation. Clin Cancer Res. 2008 Oct 01; 14(19):6023-32.
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Diammine dicarboxylic acid platinum enhances cytotoxicity in platinum-resistant ovarian cancer cells through induction of apoptosis and S-phase cell arrest. Pharm Res. 2008 Oct; 25(10):2272-82.