"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
|
| MeSH Number(s) |
G02.111.570.820.709
|
| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
|
Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 17 | 18 |
| 1997 | 7 | 15 | 22 |
| 1998 | 2 | 8 | 10 |
| 1999 | 1 | 10 | 11 |
| 2000 | 1 | 13 | 14 |
| 2001 | 0 | 12 | 12 |
| 2002 | 1 | 18 | 19 |
| 2003 | 1 | 24 | 25 |
| 2004 | 2 | 18 | 20 |
| 2005 | 1 | 17 | 18 |
| 2006 | 2 | 19 | 21 |
| 2007 | 0 | 18 | 18 |
| 2008 | 0 | 12 | 12 |
| 2009 | 3 | 20 | 23 |
| 2010 | 3 | 20 | 23 |
| 2011 | 1 | 18 | 19 |
| 2012 | 1 | 16 | 17 |
| 2013 | 3 | 22 | 25 |
| 2014 | 0 | 17 | 17 |
| 2015 | 1 | 18 | 19 |
| 2016 | 2 | 15 | 17 |
| 2017 | 0 | 17 | 17 |
| 2018 | 2 | 14 | 16 |
| 2019 | 2 | 18 | 20 |
| 2020 | 0 | 21 | 21 |
| 2021 | 0 | 13 | 13 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 4 | 4 |
| 2025 | 0 | 3 | 3 |
| 2026 | 0 | 7 | 7 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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Conformational cycling of the Wntless transporter drives trafficking and secretion of Wnt morphogens. Nat Commun. 2026 Jun 19; 17(1).
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Substituted cysteine accessibility method (SCAM) in membrane transporters studies: Learn from lactose permease. Biochimie. 2026 Aug; 247:100-113.
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Asymmetric structural transitions in the icosahedral organization of Eastern equine encephalitis virus. Nat Commun. 2026 May 15; 17(1).
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Temperature-dependent conformational dynamics govern regioselectivity in a CYP152 decarboxylase. J Biol Chem. 2026 Apr; 302(4):111309.
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Tulane virus protease as a structural surrogate for inhibitor screening of human norovirus proteases. J Virol. 2026 Mar 24; 100(3):e0217625.
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Molecular dynamics of the pathogenic KCNQ2 variant G256W reveals mechanisms of channel dysfunction in epileptic encephalopathy. J Biomol Struct Dyn. 2026 Jun; 44(9):4666-4684.
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Fyn-Saracatinib Complex Structure Reveals an Active State-like Conformation. Int J Mol Sci. 2026 Jan 23; 27(3).
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Heterogeneous Folding Intermediates Govern the Conformational Pathway of the RNA Recognition Motif Domain of the Ewing Sarcoma Protein. Biomolecules. 2025 Dec 24; 16(1).
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Non-equilibrium snapshots of ligand efficacy at the ?-opioid receptor. Nature. 2026 04; 652(8110):794-802.
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Advancements in protein structure prediction: A comparative overview of AlphaFold and its derivatives. Comput Biol Med. 2025 Apr; 188:109842.