"cdc25 Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of dual specificity phosphatases that play a role in the progression of the CELL CYCLE. They dephosphorylate and activate CYCLIN-DEPENDENT KINASES.
| Descriptor ID |
D020687
|
| MeSH Number(s) |
D08.811.277.352.650.625.225.100 D08.811.277.352.650.775.250.100 D08.811.641.755.100 D12.644.360.268.100 D12.776.167.100 D12.776.476.268.100
|
| Concept/Terms |
cdc25 Phosphatases- cdc25 Phosphatases
- Phosphatases, cdc25
- cdc25 Phosphatase
- Phosphatase, cdc25
cdc25B Phosphatase- cdc25B Phosphatase
- Phosphatase, cdc25B
- M-Phase Inducer Phosphatase 2
- M Phase Inducer Phosphatase 2
- Dual Specificity Phosphatase Cdc25B
- Cell Division Cycle 25B protein
cdc25C Phosphatase- cdc25C Phosphatase
- Phosphatase, cdc25C
- Dual Specificity Phosphatase Cdc25C
- M-Phase Inducer Phosphatase 3
- M Phase Inducer Phosphatase 3
cdc25A Phosphatase- cdc25A Phosphatase
- Phosphatase, cdc25A
- Dual Specificity Phosphatase Cdc25A
- M-Phase Inducer Phosphatase 1
- M Phase Inducer Phosphatase 1
|
Below are MeSH descriptors whose meaning is more general than "cdc25 Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "cdc25 Phosphatases".
This graph shows the total number of publications written about "cdc25 Phosphatases" by people in this website by year, and whether "cdc25 Phosphatases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 2 | 2 | 4 |
| 1998 | 5 | 3 | 8 |
| 1999 | 2 | 1 | 3 |
| 2000 | 2 | 2 | 4 |
| 2001 | 3 | 2 | 5 |
| 2002 | 5 | 1 | 6 |
| 2003 | 7 | 1 | 8 |
| 2004 | 4 | 5 | 9 |
| 2005 | 3 | 2 | 5 |
| 2007 | 3 | 0 | 3 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 1 | 2 |
| 2010 | 3 | 1 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "cdc25 Phosphatases" by people in Profiles.
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The REG? inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells. Nat Commun. 2020 08 06; 11(1):3904.
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LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice. Nat Commun. 2015 Dec 02; 6:10116.
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Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancers by modulating CDC25C/CDK1 and homologous recombination repair. Clin Cancer Res. 2013 Aug 15; 19(16):4422-32.
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RSK promotes G2/M transition through activating phosphorylation of Cdc25A and Cdc25B. Oncogene. 2014 May 01; 33(18):2385-94.
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The role of Cdc25A in the regulation of cell proliferation and apoptosis. Anticancer Agents Med Chem. 2012 Jul; 12(6):631-9.
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Contributions made by CDC25 phosphatases to proliferation of intestinal epithelial stem and progenitor cells. PLoS One. 2011 Jan 25; 6(1):e15561.
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Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):19885-90.
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Cyclin E deregulation impairs mitotic progression through premature activation of Cdc25C. Cancer Res. 2010 Jun 15; 70(12):5085-95.
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Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction. Oncogene. 2010 Jun 10; 29(23):3324-34.
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Dissecting the M phase-specific phosphorylation of serine-proline or threonine-proline motifs. Mol Biol Cell. 2010 May 01; 21(9):1470-81.