"cdc25 Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of dual specificity phosphatases that play a role in the progression of the CELL CYCLE. They dephosphorylate and activate CYCLIN-DEPENDENT KINASES.
| Descriptor ID |
D020687
|
| MeSH Number(s) |
D08.811.277.352.650.625.225.100 D08.811.277.352.650.775.250.100 D08.811.641.755.100 D12.644.360.268.100 D12.776.167.100 D12.776.476.268.100
|
| Concept/Terms |
cdc25 Phosphatases- cdc25 Phosphatases
- Phosphatases, cdc25
- cdc25 Phosphatase
- Phosphatase, cdc25
cdc25B Phosphatase- cdc25B Phosphatase
- Phosphatase, cdc25B
- M-Phase Inducer Phosphatase 2
- M Phase Inducer Phosphatase 2
- Dual Specificity Phosphatase Cdc25B
- Cell Division Cycle 25B protein
cdc25C Phosphatase- cdc25C Phosphatase
- Phosphatase, cdc25C
- Dual Specificity Phosphatase Cdc25C
- M-Phase Inducer Phosphatase 3
- M Phase Inducer Phosphatase 3
cdc25A Phosphatase- cdc25A Phosphatase
- Phosphatase, cdc25A
- Dual Specificity Phosphatase Cdc25A
- M-Phase Inducer Phosphatase 1
- M Phase Inducer Phosphatase 1
|
Below are MeSH descriptors whose meaning is more general than "cdc25 Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "cdc25 Phosphatases".
This graph shows the total number of publications written about "cdc25 Phosphatases" by people in this website by year, and whether "cdc25 Phosphatases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 1 | 3 |
| 2005 | 1 | 2 | 3 |
| 2007 | 2 | 0 | 2 |
| 2008 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "cdc25 Phosphatases" by people in Profiles.
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The REG? inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells. Nat Commun. 2020 08 06; 11(1):3904.
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RSK promotes G2/M transition through activating phosphorylation of Cdc25A and Cdc25B. Oncogene. 2014 May 01; 33(18):2385-94.
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Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):19885-90.
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Dissecting the M phase-specific phosphorylation of serine-proline or threonine-proline motifs. Mol Biol Cell. 2010 May 01; 21(9):1470-81.
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A role for microRNA in cystic liver and kidney diseases. J Clin Invest. 2008 Nov; 118(11):3585-7.
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Roles of Greatwall kinase in the regulation of cdc25 phosphatase. Mol Biol Cell. 2008 Apr; 19(4):1317-27.
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Zebrafish cdc25a is expressed during early development and limiting for post-blastoderm cell cycle progression. Dev Dyn. 2007 Dec; 236(12):3427-35.
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Regulation of Cdc25C by ERK-MAP kinases during the G2/M transition. Cell. 2007 Mar 23; 128(6):1119-32.
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Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. Cancer Res. 2007 Feb 01; 67(3):984-91.
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Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice. J Biol Chem. 2005 Oct 28; 280(43):36301-9.