"NIMA-Related Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly-conserved family of protein serine-threonine kinases that regulate the CELL CYCLE; MITOSIS; and the response to DNA DAMAGE. They are also involved in the assembly and function of microtubule-based structures such as CILIA and CENTRIOLES.
| Descriptor ID |
D000072379
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.581 D12.776.167.457
|
| Concept/Terms |
NIMA-Related Kinases- NIMA-Related Kinases
- Kinases, NIMA-Related
- NIMA Related Kinases
- NIMA Protein Kinase
- NEK Family Kinases
- Kinases, NEK Family
- NIMA Family Kinases
- Kinases, NIMA Family
- NEK Kinases
- Kinases, NEK
- NIMA-Related Protein Kinase
- NIMA Related Protein Kinase
- Never-in-Mitosis A Kinases
- Kinases, Never-in-Mitosis A
- Never in Mitosis A Kinases
|
Below are MeSH descriptors whose meaning is more general than "NIMA-Related Kinases".
Below are MeSH descriptors whose meaning is more specific than "NIMA-Related Kinases".
This graph shows the total number of publications written about "NIMA-Related Kinases" by people in this website by year, and whether "NIMA-Related Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "NIMA-Related Kinases" by people in Profiles.
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Exploring the complexity of systemic sclerosis etiology by trio whole genome sequencing. Hum Mol Genet. 2024 09 19; 33(19):1643-1647.
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Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2. Proc Natl Acad Sci U S A. 2018 10 16; 115(42):10666-10671.
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Mass Spectrometry-Based Proteomics Reveals Potential Roles of NEK9 and MAP2K4 in Resistance to PI3K Inhibition in Triple-Negative Breast Cancers. Cancer Res. 2018 05 15; 78(10):2732-2746.
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Compound heterozygous mutations in NEK8 in siblings with end-stage renal disease with hepatic and cardiac anomalies. Am J Med Genet A. 2016 Mar; 170(3):750-3.
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XCS-1, a maternally expressed gene product involved in regulating mitosis in Xenopus. J Cell Sci. 2000 Jul; 113 ( Pt 13):2497-505.
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Modulation of Xenopus oocyte-expressed phospholemman-induced ion currents by co-expression of protein kinases. Biochim Biophys Acta. 1999 Sep 21; 1451(2-3):305-18.
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Expression of a constitutively active Ca2+/calmodulin-dependent kinase in Aspergillus nidulans spores prevents germination and entry into the cell cycle. J Biol Chem. 1997 Feb 07; 272(6):3223-30.
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A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1. Mol Cell Biol. 1996 Nov; 16(11):6486-93.
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Expression of the noncatalytic domain of the NIMA kinase causes a G2 arrest in Aspergillus nidulans. EMBO J. 1994 May 01; 13(9):2103-13.
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Identification of substrate specificity determinants for the cell cycle-regulated NIMA protein kinase. J Biol Chem. 1994 Mar 04; 269(9):6603-7.