"Computational Biology" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
| Descriptor ID |
D019295
|
| MeSH Number(s) |
H01.158.273.180 L01.313.124
|
| Concept/Terms |
Computational Molecular Biology- Computational Molecular Biology
- Biologies, Computational Molecular
- Biology, Computational Molecular
- Computational Molecular Biologies
- Molecular Biologies, Computational
- Molecular Biology, Computational
Bio-Informatics- Bio-Informatics
- Bio Informatics
- Bio-Informatic
- Bioinformatics
- Bioinformatic
|
Below are MeSH descriptors whose meaning is more general than "Computational Biology".
Below are MeSH descriptors whose meaning is more specific than "Computational Biology".
This graph shows the total number of publications written about "Computational Biology" by people in this website by year, and whether "Computational Biology" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 2000 | 2 | 2 | 4 |
| 2001 | 3 | 1 | 4 |
| 2002 | 2 | 1 | 3 |
| 2003 | 5 | 5 | 10 |
| 2004 | 8 | 13 | 21 |
| 2005 | 7 | 12 | 19 |
| 2006 | 14 | 14 | 28 |
| 2007 | 3 | 11 | 14 |
| 2008 | 6 | 13 | 19 |
| 2009 | 8 | 13 | 21 |
| 2010 | 8 | 15 | 23 |
| 2011 | 3 | 21 | 24 |
| 2012 | 9 | 14 | 23 |
| 2013 | 13 | 23 | 36 |
| 2014 | 12 | 16 | 28 |
| 2015 | 3 | 19 | 22 |
| 2016 | 13 | 18 | 31 |
| 2017 | 17 | 26 | 43 |
| 2018 | 10 | 23 | 33 |
| 2019 | 27 | 17 | 44 |
| 2020 | 18 | 19 | 37 |
| 2021 | 12 | 24 | 36 |
| 2022 | 3 | 8 | 11 |
| 2023 | 2 | 7 | 9 |
| 2024 | 3 | 14 | 17 |
| 2025 | 14 | 12 | 26 |
To return to the timeline,
click here.
Below are the most recent publications written about "Computational Biology" by people in Profiles.
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DeepMVP: deep learning models trained on high-quality data accurately predict PTM sites and variant-induced alterations. Nat Methods. 2025 Sep; 22(9):1857-1867.
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Computationally resolved neuroprogenitor cell biomarkers associate with human disorders. Stem Cell Reports. 2025 Sep 09; 20(9):102606.
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Implementing a training resource for large-scale genomic data analysis in the All of Us Researcher Workbench. Am J Hum Genet. 2025 Sep 04; 112(9):2001-2009.
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Apollo: a comprehensive GPU-powered within-host simulator for viral evolution and infection dynamics across population, tissue, and cell. Nat Commun. 2025 Jul 01; 16(1):5783.
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Parameterization of intraoperative human microelectrode recordings: Linking action potential morphology to brain anatomy. PLoS Comput Biol. 2025 Jun; 21(6):e1013184.
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Stochastic gene expression in proliferating cells: Differing noise intensity in single-cell and population perspectives. PLoS Comput Biol. 2025 Jun; 21(6):e1013014.
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Comprehensive evaluation of phosphoproteomic-based kinase activity inference. Nat Commun. 2025 May 22; 16(1):4771.
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CellLENS enables cross-domain information fusion for enhanced cell population delineation in single-cell spatial omics data. Nat Immunol. 2025 Jun; 26(6):963-974.
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Inferring synaptic transmission from the stochastic dynamics of the quantal content: An analytical approach. PLoS Comput Biol. 2025 May; 21(5):e1013067.
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Computational modeling of cancer cell metabolism along the catabolic-anabolic axes. NPJ Syst Biol Appl. 2025 May 10; 11(1):46.