"Systems Biology" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.
| Descriptor ID |
D049490
|
| MeSH Number(s) |
H01.158.273.180.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Systems Biology".
Below are MeSH descriptors whose meaning is more specific than "Systems Biology".
This graph shows the total number of publications written about "Systems Biology" by people in this website by year, and whether "Systems Biology" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 3 | 4 |
| 2009 | 2 | 2 | 4 |
| 2010 | 5 | 2 | 7 |
| 2011 | 2 | 4 | 6 |
| 2012 | 4 | 2 | 6 |
| 2013 | 6 | 3 | 9 |
| 2014 | 2 | 3 | 5 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 4 | 5 |
| 2018 | 5 | 1 | 6 |
| 2019 | 2 | 1 | 3 |
| 2020 | 2 | 1 | 3 |
| 2021 | 3 | 2 | 5 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Systems Biology" by people in Profiles.
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A systems biology-based identification and in?vivo functional screening of Alzheimer's disease risk genes reveal modulators of memory function. Neuron. 2024 Jul 03; 112(13):2112-2129.e4.
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Systems biology approach to functionally assess the Clostridioides difficile pangenome reveals genetic diversity with discriminatory power. Proc Natl Acad Sci U S A. 2022 05 03; 119(18):e2119396119.
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Systems biology analysis of human genomes points to key pathways conferring spina bifida risk. Proc Natl Acad Sci U S A. 2021 12 21; 118(51).
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Perspectives for systems biology in the management of tuberculosis. Eur Respir Rev. 2021 Jun 30; 30(160).
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An integrative analysis to distinguish between emphysema (EML) and alpha-1 antitrypsin deficiency-related emphysema (ADL)-A systems biology approach. Adv Protein Chem Struct Biol. 2021; 127:315-342.
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Obstructive Sleep Apnea and Dementia-Common Gene Associations through Network-Based Identification of Common Driver Genes. Genes (Basel). 2021 04 09; 12(4).
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A systemic approach to explore the mechanisms of drug resistance and altered signaling cascades in extensively drug-resistant tuberculosis. Adv Protein Chem Struct Biol. 2021; 127:343-364.
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Bayesian inference for biophysical neuron models enables stimulus optimization for retinal neuroprosthetics. Elife. 2020 10 27; 9.
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Therapeutic Opportunities for Intestinal Angioectasia- Targeting PPAR? and Oxidative Stress. Clin Transl Sci. 2021 03; 14(2):518-528.
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Systems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic divergence. NPJ Syst Biol Appl. 2020 10 20; 6(1):31.