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MIRJANA MALETIC-SAVATIC

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1250 MOURSUND STREET
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neurology
    DivisionNeurology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience
    DivisionNeuroscience


    Collapse Research 
    Collapse research activities and funding
    R01MH130356     (SAHIN, MUSTAFA)Mar 10, 2023 - Feb 29, 2028
    NIH
    Effects of 16p11.2 copy number variation on neuronal development and pathology
    Role: Co-Principal Investigator
    R01AG076942     (MALETIC-SAVATIC, MIRJANA)Jun 1, 2022 - Feb 28, 2027
    NIH
    Using MR Spectroscopy to Measure Mammalian Neurogenesis in Vivo
    Role: Principal Investigator
    R01GM120033     (MALETIC-SAVATIC, MIRJANA)Jan 1, 2017 - Dec 31, 2021
    NIH
    Advanced Computational Approaches for NMR Data-mining
    Role: Principal Investigator
    R21NS053875     (MALETIC-SAVATIC, MIRJANA)Sep 15, 2006 - Nov 30, 2008
    NIH
    Identification and tracking of neural stem cells in vivo: a metabolomic approach
    Role: Principal Investigator
    K08NS044276     (MALETIC-SAVATIC, MIRJANA)Jul 5, 2002 - Jun 30, 2007
    NIH
    Activity-dependent control: neural progenitor cell fate
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ross R, O'Neill KA, Betensky RA, Billiet T, Kenney R, Lovett JT, Maletic-Savatic M, Meeks HD, Sosa A, Waltz M, Krupp LB. Association of Social Determinants of Health With Brain MRI Outcomes in Individuals With Pediatric Onset Multiple Sclerosis. Neurology. 2024 Dec 24; 103(12):e210140. PMID: 39602667.
      Citations:    Fields:    Translation:Humans
    2. Khalil SM, Cappuccio G, Li F, Maletic-Savatic M. Molecular Imaging of Human Brain Organoids Using Mass Spectrometry. J Vis Exp. 2024 Sep 27; (211). PMID: 39400180.
      Citations:    Fields:    Translation:Humans
    3. Khalil SM, Qin X, Hakenjos JM, Wang J, Hu Z, Liu X, Wang J, Maletic-Savatic M, MacKenzie KR, Matzuk MM, Li F. MALDI Imaging Mass Spectrometry Visualizes the Distribution of Antidepressant Duloxetine and Its Major Metabolites in Mouse Brain, Liver, Kidney, and Spleen Tissues. Drug Metab Dispos. 2024 Jun 17; 52(7):673-680. PMID: 38658163; PMCID: PMC11185819.
      Citations:    Fields:    Translation:Animals
    4. Sandoval SO, Cappuccio G, Kruth K, Osenberg S, Khalil SM, M?ndez-Albelo NM, Padmanabhan K, Wang D, Niciu MJ, Bhattacharyya A, Stein JL, Sousa AMM, Waxman EA, Buttermore ED, Whye D, Sirois CL, Cross-IDDRC Human Stem Cell Consortium, Williams A, Maletic-Savatic M, Zhao X. Rigor and reproducibility in human brain organoid research: Where we are and where we need to go. Stem Cell Reports. 2024 Jun 11; 19(6):796-816. PMID: 38759644; PMCID: PMC11297560.
      Citations: 2     Fields:    Translation:Humans
    5. Khalil SM, MacKenzie KR, Maletic-Savatic M, Li F. Metabolic bioactivation of antidepressants: advance and underlying hepatotoxicity. Drug Metab Rev. 2024 Feb-May; 56(2):97-126. PMID: 38311829; PMCID: PMC11118075.
      Citations:    Fields:    Translation:HumansAnimals
    6. Allison K, Maletic-Savatic M, Pehlivan D. MECP2-related disorders while gene-based therapies are on the horizon. Front Genet. 2024; 15:1332469. PMID: 38410154; PMCID: PMC10895005.
      Citations: 2     
    7. Jonnakuti VS, Wagner EJ, Maletic-Savatic M, Liu Z, Yalamanchili HK. PolyAMiner-Bulk is a deep learning-based algorithm that decodes alternative polyadenylation dynamics from bulk RNA-seq data. Cell Rep Methods. 2024 Feb 26; 4(2):100707. PMID: 38325383; PMCID: PMC10921021.
      Citations: 2     Fields:    Translation:HumansCells
    8. Guan F, Zhao L, Bronk JK, Maletic-Savatic M, Grosshans DR, Carlson DJ. Editorial: Advances in the biological effects of ionizing radiation. Front Oncol. 2023; 13:1352771. PMID: 38234403; PMCID: PMC10793655.
      Citations:    
    9. Mendonca D, Cappuccio G, Sheppard J, Delacruz M, Bengtsson J, Carvalho CMB, Bajic A, Park H, Kim JJ, Jafar-Nejad P, Coquery C, Pehlivan D, Suter B, Maletic-Savatic M. Generation of five induced pluripotent stem cell lines from patients with MECP2 Duplication Syndrome. Stem Cell Res. 2024 02; 74:103292. PMID: 38154383; PMCID: PMC10898976.
      Citations:    Fields:    Translation:HumansCells
    10. Han X, Wang W, Ma LH, Ai-Ramahi I, Botas J, MacKenzie K, Allen GI, Young DW, Liu Z, Maletic-Savatic M. SPA-STOCSY: an automated tool for identifying annotated and non-annotated metabolites in high-throughput NMR spectra. Bioinformatics. 2023 10 03; 39(10). PMID: 37792497; PMCID: PMC10568371.
      Citations:    Fields:    Translation:HumansAnimals
    11. Cappuccio G, Khalil SM, Osenberg S, Li F, Maletic-Savatic M. Mass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids. Front Mol Biosci. 2023; 10:1181965. PMID: 37304070; PMCID: PMC10251497.
      Citations: 2     
    12. Wang W, Ma LH, Maletic-Savatic M, Liu Z. NMRQNet: a deep learning approach for automatic identification and quantification of metabolites using Nuclear Magnetic Resonance (NMR) in human plasma samples. bioRxiv. 2023 Mar 02. PMID: 36909516; PMCID: PMC10002723.
      Citations:    
    13. Han X, Wang W, Ma LH, Al-Ramahi I, Botas J, MacKenzie K, Allen GI, Young DW, Liu Z, Maletic-Savatic M. SPA-STOCSY: An Automated Tool for Identification of Annotated and Non-Annotated Metabolites in High-Throughput NMR Spectra. bioRxiv. 2023 Feb 22. PMID: 36865102; PMCID: PMC9980041.
      Citations:    
    14. Jonnakuti VS, Wagner EJ, Maletic-Savatic M, Liu Z, Yalamanchili HK. PolyAMiner-Bulk: A Machine Learning Based Bioinformatics Algorithm to Infer and Decode Alternative Polyadenylation Dynamics from bulk RNA-seq data. bioRxiv. 2023 Jan 24. PMID: 36747700; PMCID: PMC9900750.
      Citations:    
    15. Sun J, Osenberg S, Irwin A, Ma LH, Lee N, Xiang Y, Li F, Wan YW, Park IH, Maletic-Savatic M, Ballas N. Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation. Cell Rep. 2023 01 31; 42(1):111942. PMID: 36640327; PMCID: PMC10857774.
      Citations: 1     Fields:    Translation:HumansCells
    16. Wang L, Maletic-Savatic M, Liu Z. Region-specific denoising identifies spatial co-expression patterns and intra-tissue heterogeneity in spatially resolved transcriptomics data. Nat Commun. 2022 11 14; 13(1):6912. PMID: 36376296; PMCID: PMC9663444.
      Citations: 1     Fields:    Translation:Cells
    17. Bokhari RS, Beheshti A, Blutt SE, Bowles DE, Brenner D, Britton R, Bronk L, Cao X, Chatterjee A, Clay DE, Courtney C, Fox DT, Gaber MW, Gerecht S, Grabham P, Grosshans D, Guan F, Jezuit EA, Kirsch DG, Liu Z, Maletic-Savatic M, Miller KM, Montague RA, Nagpal P, Osenberg S, Parkitny L, Pierce NA, Porada C, Rosenberg SM, Sargunas P, Sharma S, Spangler J, Tavakol DN, Thomas D, Vunjak-Novakovic G, Wang C, Whitcomb L, Young DW, Donoviel D. Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel. Life Sci Space Res (Amst). 2022 Nov; 35:105-112. PMID: 36336356.
      Citations:    Fields:    Translation:HumansAnimalsPHPublic Health
    18. McNerlin C, Guan F, Bronk L, Lei K, Grosshans D, Young DW, Gaber MW, Maletic-Savatic M. Targeting hippocampal neurogenesis to protect astronauts' cognition and mood from decline due to space radiation effects. Life Sci Space Res (Amst). 2022 Nov; 35:170-179. PMID: 36336363.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    19. Spruill ML, Maletic-Savatic M, Martin H, Li F, Liu X. Spatial analysis of drug absorption, distribution, metabolism, and toxicology using mass spectrometry imaging. Biochem Pharmacol. 2022 07; 201:115080. PMID: 35561842; PMCID: PMC9744413.
      Citations:    Fields:    
    20. Kandel P, Semerci F, Mishra R, Choi W, Bajic A, Baluya D, Ma L, Chen K, Cao AC, Phongmekhin T, Matinyan N, Chamakuri S, Raji IO, Chang L, Fuentes-Prior P, MacKenzie KR, Benn CL, Venken K, Moore DD, Young DW, Maletic-Savatic M, Jim?nez-Panizo A, Est?banez-Perpi?? E. Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2022 03 29; 119(13):e2023784119. PMID: 35333654; PMCID: PMC9060471.
      Citations: 1     Fields:    Translation:Animals
    21. Manganas LN, Osenberg S, Semerci F, Tosun M, Mishra R, Parkitny L, Encinas JM, Maletic-Savatic M, Dur? I. Author Correction: BASP1 labels neural stem cells in the neurogenic niches of mammalian brain. Sci Rep. 2021 Oct 04; 11(1):20008. PMID: 34608270; PMCID: PMC8490396.
      Citations:    Fields:    
    22. Parkitny L, Maletic-Savatic M. Glial PAMPering and DAMPening of Adult Hippocampal Neurogenesis. Brain Sci. 2021 Sep 29; 11(10). PMID: 34679362; PMCID: PMC8533961.
      Citations: 1     
    23. Manganas LN, Osenberg S, Semerci F, Tosun M, Mishra R, Parkitny L, Encinas JM, Maletic-Savatic M, Dur? I. BASP1 labels neural stem cells in the neurogenic niches of mammalian brain. Sci Rep. 2021 03 10; 11(1):5546. PMID: 33692421; PMCID: PMC7970918.
      Citations:    Fields:    Translation:AnimalsCells
    24. Semerci F, Parkitny L, Maletic-Savatic M. Mouse Models for Studying Hippocampal Adult Neural Stem Cell Biology. Methods Mol Biol. 2021; 2224:61-74. PMID: 33606206.
      Citations: 1     Fields:    Translation:AnimalsCells
    25. MacKenzie KR, Zhao M, Barzi M, Wang J, Bissig KD, Maletic-Savatic M, Jung SY, Li F. Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine. Eur J Pharm Sci. 2020 Oct 01; 153:105488. PMID: 32712217; PMCID: PMC7506503.
      Citations: 2     Fields:    Translation:AnimalsCells
    26. Diaz-Aparicio I, Sierra-Torre V, Plaza-Zabala A, Beccari S, Huguet P, Abiega O, Alberdi E, Matute C, Bernales I, Otrokocsi L, Sperlagh B, Happonen KE, Lemke G, Maletic-Savatic M, Valero J, Sierra A, Paris I, Rodr?guez-Iglesias N, M?rquez-Ropero M, Schulz A. Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome. J Neurosci. 2020 02 12; 40(7):1453-1482. PMID: 31896673; PMCID: PMC7044727.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    27. Lucassen PJ, Fitzsimons CP, Salta E, Maletic-Savatic M. Adult neurogenesis, human after all (again): Classic, optimized, and future approaches. Behav Brain Res. 2020 03 02; 381:112458. PMID: 31899214.
      Citations: 27     Fields:    Translation:HumansCells
    28. Chen K, Baluya D, Tosun M, Li F, Maletic-Savatic M. Imaging Mass Spectrometry: A New Tool to Assess Molecular Underpinnings of Neurodegeneration. Metabolites. 2019 Jul 10; 9(7). PMID: 31295847; PMCID: PMC6681116.
      Citations: 7     
    29. Lucassen PJ, van Dam AM, Kandel P, Bielefeld P, Korosi A, Fitzsimons CP, Maletic-Savatic M. The orphan nuclear receptor TLX: an emerging master regulator of cross-talk between microglia and neural precursor cells. Neuronal Signal. 2019 06; 3(2):NS20180208. PMID: 32271856; PMCID: PMC7104320.
      Citations: 2     
    30. Tosun M, Semerci F, Maletic-Savatic M. Heterogeneity of Stem Cells in the Hippocampus. Adv Exp Med Biol. 2019; 1169:31-53. PMID: 31487017.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    31. Choi WT, Tosun M, Jeong HH, Karakas C, Semerci F, Liu Z, Maletic-Savatic M. Metabolomics of mammalian brain reveals regional differences. BMC Syst Biol. 2018 12 21; 12(Suppl 8):127. PMID: 30577853; PMCID: PMC6302375.
      Citations: 11     Fields:    Translation:Animals
    32. Jiang X, Zhang C, Chen J, Choi S, Zhou Y, Zhao M, Song X, Chen X, Maletic-Savatic M, Palzkill T, Moore D, Wang MC, Wang J. Quantitative Real-Time Imaging of Glutathione with Subcellular Resolution. Antioxid Redox Signal. 2019 06 01; 30(16):1900-1910. PMID: 30358421; PMCID: PMC6486671.
      Citations: 8     Fields:    Translation:HumansCells
    33. Kadur Lakshminarasimha Murthy P, Srinivasan T, Bochter MS, Xi R, Varanko AK, Tung KL, Semerci F, Xu K, Maletic-Savatic M, Cole SE, Shen X. Radical and lunatic fringes modulate notch ligands to support mammalian intestinal homeostasis. Elife. 2018 04 09; 7. PMID: 29629872; PMCID: PMC5896954.
      Citations: 7     Fields:    Translation:AnimalsCells
    34. Tang C, Chen K, Bajic A, Choi WT, Baluya DL, Maletic-Savatic M. Analytical Platforms and Techniques to Study Stem Cell Metabolism. Methods Mol Biol. 2018; 1842:265-281. PMID: 30196417.
      Citations: 2     Fields:    Translation:HumansCells
    35. Beccari S, Valero J, Maletic-Savatic M, Sierra A. A simulation model of neuroprogenitor proliferation dynamics predicts age-related loss of hippocampal neurogenesis but not astrogenesis. Sci Rep. 2017 11 28; 7(1):16528. PMID: 29184142; PMCID: PMC5705784.
      Citations: 9     Fields:    Translation:AnimalsCells
    36. Gandy K, Kim S, Sharp C, Dindo L, Maletic-Savatic M, Calarge C. Pattern Separation: A Potential Marker of Impaired Hippocampal Adult Neurogenesis in Major Depressive Disorder. Front Neurosci. 2017; 11:571. PMID: 29123464; PMCID: PMC5662616.
      Citations: 16     
    37. Jiang X, Chen J, Bajic A, Zhang C, Song X, Carroll SL, Cai ZL, Tang M, Xue M, Cheng N, Schaaf CP, Li F, MacKenzie KR, Ferreon ACM, Xia F, Wang MC, Maletic-Savatic M, Wang J. Corrigendum: Quantitative real-time imaging of glutathione. Nat Commun. 2017 10 03; 8:16163. PMID: 28972204; PMCID: PMC5628253.
      Citations: 2     Fields:    
    38. Li B, Sierra A, Deudero JJ, Semerci F, Laitman A, Kimmel M, Maletic-Savatic M. Multitype Bellman-Harris branching model provides biological predictors of early stages of adult hippocampal neurogenesis. BMC Syst Biol. 2017 Oct 03; 11(Suppl 5):90. PMID: 28984196; PMCID: PMC5629620.
      Citations: 9     Fields:    Translation:HumansAnimals
    39. Liu L, MacKenzie KR, Putluri N, Maletic-Savatic M, Bellen HJ. The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D. Cell Metab. 2017 Nov 07; 26(5):719-737.e6. PMID: 28965825; PMCID: PMC5677551.
      Citations: 131     Fields:    Translation:HumansAnimalsCells
    40. Jiang X, Chen J, Bajic A, Zhang C, Song X, Carroll SL, Cai ZL, Tang M, Xue M, Cheng N, Schaaf CP, Li F, MacKenzie KR, Ferreon ACM, Xia F, Wang MC, Maletic-Savatic M, Wang J. Quantitative real-time imaging of glutathione. Nat Commun. 2017 07 13; 8:16087. PMID: 28703127; PMCID: PMC5511354.
      Citations: 47     Fields:    Translation:HumansCells
    41. Semerci F, Choi WT, Bajic A, Thakkar A, Encinas JM, Depreux F, Segil N, Groves AK, Maletic-Savatic M. Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance. Elife. 2017 07 12; 6. PMID: 28699891; PMCID: PMC5531831.
      Citations: 22     Fields:    Translation:AnimalsCells
    42. Maletic-Savatic M. A question of fate. PLoS Biol. 2017 05; 15(5):e2002329. PMID: 28505150; PMCID: PMC5432065.
      Citations:    Fields:    Translation:HumansAnimalsCells
    43. Bielefeld P, Sierra A, Encinas JM, Maletic-Savatic M, Anderson A, Fitzsimons CP. A Standardized Protocol for Stereotaxic Intrahippocampal Administration of Kainic Acid Combined with Electroencephalographic Seizure Monitoring in Mice. Front Neurosci. 2017; 11:160. PMID: 28405182; PMCID: PMC5370320.
      Citations: 10     
    44. Basch ML, Brown RM, Jen HI, Semerci F, Depreux F, Zhang H, Norton CR, Gridley T, Cole SE, Doetzlhofer A, Maletic-Savatic M, Segil N, Groves AK, Edlund RK. Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife. 2016 12 14; 5. PMID: 27966429; PMCID: PMC5215100.
      Citations: 29     Fields:    Translation:AnimalsCells
    45. Cvoro A, Bajic A, Zhang A, Simon M, Golic I, Sieglaff DH, Maletic-Savatic M, Korac A, Webb P. Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells. PLoS One. 2016; 11(10):e0164407. PMID: 27732649; PMCID: PMC5061422.
      Citations: 6     Fields:    Translation:HumansCells
    46. Abiega O, Beccari S, Diaz-Aparicio I, Nadjar A, Leyrolle Q, Valero J, Savage JC, Hui CW, Deudero JJ, Brewster AL, Anderson AE, Zaldumbide L, Galbarriatu L, Marinas A, Vivanco MD, Matute C, Maletic-Savatic M, Encinas JM, Sierra A, Lay? S, G?mez-Nicola D, Domercq M, P?rez-Samart?n A, S?nchez-Zafra V, Paris I, Tremblay M?. Correction: Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling. PLoS Biol. 2016 09; 14(9):e1002554. PMID: 27649285; PMCID: PMC5029941.
      Citations: 4     Fields:    
    47. Abiega O, Beccari S, Diaz-Aparicio I, Nadjar A, Leyrolle Q, Valero J, Savage JC, Hui CW, Deudero JJ, Brewster AL, Anderson AE, Zaldumbide L, Galbarriatu L, Marinas A, Vivanco MD, Matute C, Maletic-Savatic M, Encinas JM, Sierra A, Lay? S, G?mez-Nicola D, Domercq M, P?rez-Samart?n A, S?nchez-Zafra V, Paris I, Tremblay M?. Correction: Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling. PLoS Biol. 2016 Jun; 14(6):e1002508. PMID: 27362865; PMCID: PMC4928863.
      Citations: 2     Fields:    
    48. Semerci F, Maletic-Savatic M. Transgenic mouse models for studying adult neurogenesis. Front Biol (Beijing). 2016 Jun; 11(3):151-167. PMID: 28473846; PMCID: PMC5412727.
      Citations: 16     
    49. Abiega O, Beccari S, Diaz-Aparicio I, Valero J, Deudero JJ, Brewster AL, Anderson AE, Zaldumbide L, Galbarriatu L, Marinas A, Vivanco Md, Matute C, Encinas JM, Sierra A, Nadjar A, Lay? S, Leyrolle Q, G?mez-Nicola D, Domercq M, P?rez-Samart?n A, S?nchez-Zafra V, Paris I, Savage JC, Hui CW, Tremblay M?, Maletic-Savatic M. Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling. PLoS Biol. 2016 05; 14(5):e1002466. PMID: 27228556; PMCID: PMC4881984.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    50. Zhang X, Tang Y, Maletic-Savatic M, Sheng J, Zhang X, Zhu Y, Zhang T, Wang J, Tong S, Wang J, Li Y. Altered neuronal spontaneous activity correlates with glutamate concentration in medial prefrontal cortex of major depressed females: An fMRI-MRS study. J Affect Disord. 2016 Sep 01; 201:153-61. PMID: 27235818.
      Citations: 11     Fields:    Translation:HumansCells
    51. Pati S, Muthuraju S, Hadi RA, Huat TJ, Singh S, Maletic-Savatic M, Abdullah JM, Jaafar H. Neurogenic plasticity of mesenchymal stem cell, an alluring cellular replacement for traumatic brain injury. Curr Stem Cell Res Ther. 2016; 11(2):149-57. PMID: 26763886.
      Citations: 5     Fields:    Translation:HumansCells
    52. Hasan KM, Mwangi B, Cao B, Keser Z, Tustison NJ, Kochunov P, Frye RE, Savatic M, Soares J. Entorhinal Cortex Thickness across the Human Lifespan. J Neuroimaging. 2016 05; 26(3):278-82. PMID: 26565394; PMCID: PMC4826319.
      Citations: 12     Fields:    Translation:Humans
    53. Botas A, Campbell HM, Han X, Maletic-Savatic M. Metabolomics of neurodegenerative diseases. Int Rev Neurobiol. 2015; 122:53-80. PMID: 26358890.
      Citations: 14     Fields:    Translation:Humans
    54. Erramuzpe A, Encinas JM, Sierra A, Maletic-Savatic M, Brewster AL, Anderson AE, Stramaglia S, Cortes JM. Longitudinal variations of brain functional connectivity: A case report study based on a mouse model of epilepsy. F1000Res. 2015; 4:144. PMID: 26167275; PMCID: PMC4482210.
      Citations: 2     Fields:    
    55. Aelvoet SA, Abiega O, Deudero JJ, Brewster AL, Bernales I, Anderson AE, Baekelandt V, Maletic-Savatic M, Sierra A, Mart?n-Su?rez S, Valc?rcel-Mart?n R, Pascual-Brazo J, Encinas JM. Neuronal hyperactivity accelerates depletion of neural stem cells and impairs hippocampal neurogenesis. Cell Stem Cell. 2015 May 07; 16(5):488-503. PMID: 25957904; PMCID: PMC4443499.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    56. Arnold JM, Choi WT, Sreekumar A, Maletic-Savatic M. Analytical strategies for studying stem cell metabolism. Front Biol (Beijing). 2015 Apr; 10(2):141-153. PMID: 26213533; PMCID: PMC4512307.
      Citations: 7     
    57. Zhu Y, Fan Q, Han X, Zhang H, Chen J, Wang Z, Zhang Z, Tan L, Xiao Z, Tong S, Maletic-Savatic M, Li Y. Decreased thalamic glutamate level in unmedicated adult obsessive-compulsive disorder patients detected by proton magnetic resonance spectroscopy. J Affect Disord. 2015 Jun 01; 178:193-200. PMID: 25819113.
      Citations: 7     Fields:    Translation:HumansCells
    58. Pati S, Supeno NE, Muthuraju S, Abdul Hadi R, Ghani AR, Idris FM, Maletic-Savatic M, Abdullah JM, Jaafar H. MicroRNA profiling reveals unique miRNA signatures in IGF-1 treated embryonic striatal stem cell fate decisions in striatal neurogenesis in vitro. Biomed Res Int. 2014; 2014:503162. PMID: 25254208; PMCID: PMC4165568.
      Citations: 10     Fields:    Translation:HumansCells
    59. Shetty AN, Chiang S, Maletic-Savatic M, Kasprian G, Vannucci M, Lee W. Spatial Mapping of Translational Diffusion Coefficients Using Diffusion Tensor Imaging: A Mathematical Description. Concepts Magn Reson Part A Bridg Educ Res. 2014 Jan; 43(1):1-27. PMID: 27441031; PMCID: PMC4948124.
      Citations: 1     
    60. Abraham AB, Bronstein R, Reddy AS, Maletic-Savatic M, Aguirre A, Tsirka SE. Aberrant neural stem cell proliferation and increased adult neurogenesis in mice lacking chromatin protein HMGB2. PLoS One. 2013; 8(12):e84838. PMID: 24391977; PMCID: PMC3877347.
      Citations: 13     Fields:    Translation:AnimalsCells
    61. Peterson C, Vannucci M, Karakas C, Choi W, Ma L, Maletic-Savatic M. Inferring metabolic networks using the Bayesian adaptive graphical lasso with informative priors. Stat Interface. 2013 Oct 01; 6(4):547-558. PMID: 24533172; PMCID: PMC3922235.
      Citations: 10     
    62. Allen GI, Peterson C, Vannucci M, Maletic-Savatic M. Regularized Partial Least Squares with an Application to NMR Spectroscopy. Stat Anal Data Min. 2013 Aug 01; 6(4):302-314. PMID: 24511361; PMCID: PMC3914316.
      Citations: 7     
    63. Wiszniewski W, Hunter JV, Hanchard NA, Willer JR, Shaw C, Tian Q, Illner A, Wang X, Cheung SW, Patel A, Campbell IM, Gelowani V, Hixson P, Ester AR, Azamian MS, Potocki L, Zapata G, Hernandez PP, Ramocki MB, Santos-Cortez RL, Wang G, York MK, Justice MJ, Chu ZD, Bader PI, Omo-Griffith L, Madduri NS, Scharer G, Crawford HP, Yanatatsaneejit P, Eifert A, Kerr J, Bacino CA, Franklin AI, Goin-Kochel RP, Simpson G, Immken L, Haque ME, Stosic M, Williams MD, Morgan TM, Pruthi S, Omary R, Boyadjiev SA, Win KK, Thida A, Hurles M, Hibberd ML, Khor CC, Van Vinh Chau N, Gallagher TE, Mutirangura A, Stankiewicz P, Beaudet AL, Maletic-Savatic M, Rosenfeld JA, Shaffer LG, Davis EE, Belmont JW, Dunstan S, Simmons CP, Bonnen PE, Leal SM, Katsanis N, Lupski JR, Lalani SR. TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities. Am J Hum Genet. 2013 Aug 08; 93(2):197-210. PMID: 23810381; PMCID: PMC3738832.
      Citations: 22     Fields:    Translation:HumansCells
    64. Vingara LK, Yu HJ, Wagshul ME, Serafin D, Christodoulou C, Krupp LB, Maletic-Savatic M, Pelczer I. Metabolomic approach to human brain spectroscopy identifies associations between clinical features and the frontal lobe metabolome in multiple sclerosis. Neuroimage. 2013 Nov 15; 82:586-94. PMID: 23751863; PMCID: PMC3975905.
      Citations: 11     Fields:    Translation:Humans
    65. Abraham AB, Bronstein R, Chen EI, Koller A, Ronfani L, Maletic-Savatic M, Tsirka SE. Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells. Proteome Sci. 2013 Apr 27; 11(1):18. PMID: 23621913; PMCID: PMC3708756.
      Citations: 17     
    66. Valenzuela M, Bartres-Faz D, Bullmore E, Fjell A, Maletic-Savetic M, Martins R, Solowij N, Y?cel M. More thinking about less data: a perspective from the 2nd Provence Summer Workshop. Mol Psychiatry. 2013 May; 18(5):524-5. PMID: 23478747.
      Citations:    Fields:    Translation:Humans
    67. Yu HJ, Christodoulou C, Bhise V, Greenblatt D, Patel Y, Serafin D, Maletic-Savatic M, Krupp LB, Wagshul ME. Multiple white matter tract abnormalities underlie cognitive impairment in RRMS. Neuroimage. 2012 Feb 15; 59(4):3713-22. PMID: 22062194.
      Citations: 54     Fields:    Translation:Humans
    68. Allen GI, Maletic-Savatic M. Sparse non-negative generalized PCA with applications to metabolomics. Bioinformatics. 2011 Nov 01; 27(21):3029-35. PMID: 21930672; PMCID: PMC3198582.
      Citations: 6     Fields:    
    69. Sierra A, Encinas JM, Maletic-Savatic M. Adult human neurogenesis: from microscopy to magnetic resonance imaging. Front Neurosci. 2011; 5:47. PMID: 21519376; PMCID: PMC3075882.
      Citations: 38     
    70. Ma LH, Li Y, Djuric PM, Maletic-Savatic M. Systems biology approach to imaging of neural stem cells. Methods Mol Biol. 2011; 711:421-34. PMID: 21279615; PMCID: PMC3975906.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    71. Sierra A, Encinas JM, Deudero JJ, Chancey JH, Enikolopov G, Overstreet-Wadiche LS, Tsirka SE, Maletic-Savatic M. Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. Cell Stem Cell. 2010 Oct 08; 7(4):483-95. PMID: 20887954; PMCID: PMC4008496.
      Citations: 597     Fields:    Translation:AnimalsCells
    72. Malinow R, Hayashi Y, Maletic-Savatic M, Zaman SH, Poncer JC, Shi SH, Osten P, Seidenman K, Esteban JA. Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection. Cold Spring Harb Protoc. 2010 Apr; 2010(4):pdb.prot5406. PMID: 20360360; PMCID: PMC3923632.
      Citations: 20     Fields:    Translation:Cells
    73. Maletic-Savatic M, Vingara LK, Manganas LN, Li Y, Zhang S, Sierra A, Hazel R, Smith D, Wagshul ME, Henn F, Krupp L, Enikolopov G, Benveniste H, Djuric PM, Pelczer I. Metabolomics of neural progenitor cells: a novel approach to biomarker discovery. Cold Spring Harb Symp Quant Biol. 2008; 73:389-401. PMID: 19022759; PMCID: PMC4037147.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    74. Djuric PM, Benveniste H, Wagshul ME, Henn F, Enikolopov G, Maletic-Savatic M. Response to Comments on "Magnetic Resonance Spectroscopy Identifies Neural Progenitor Cells in the Live Human Brain". Science. 2008 Aug 01; 321(5889):640. PMID: 26380846; PMCID: PMC4576718.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    75. Manganas LN, Zhang X, Li Y, Hazel RD, Smith SD, Wagshul ME, Henn F, Benveniste H, Djuric PM, Enikolopov G, Maletic-Savatic M. Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain. Science. 2007 Nov 09; 318(5852):980-5. PMID: 17991865; PMCID: PMC4039561.
      Citations: 164     Fields:    Translation:HumansAnimalsCells
    76. Mignone JL, Roig-Lopez JL, Fedtsova N, Schones DE, Manganas LN, Maletic-Savatic M, Keyes WM, Mills AA, Gleiberman A, Zhang MQ, Enikolopov G. Neural potential of a stem cell population in the hair follicle. Cell Cycle. 2007 Sep 01; 6(17):2161-70. PMID: 17873521; PMCID: PMC3789384.
      Citations: 33     Fields:    Translation:AnimalsCells
    77. Manganas LN, Maletic-Savatic M. Stem cell therapy for central nervous system demyelinating disease. Curr Neurol Neurosci Rep. 2005 May; 5(3):225-31. PMID: 15865888; PMCID: PMC4031751.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    78. Nasr JT, Gabis L, Savatic M, Andriola MR. The Electroencephalogram in Children with Developmental Dysphasia. Epilepsy Behav. 2001 Apr; 2(2):115-118. PMID: 12609193.
      Citations: 2     Fields:    
    79. Mainen ZF, Maletic-Savatic M, Shi SH, Hayashi Y, Malinow R, Svoboda K. Two-photon imaging in living brain slices. Methods. 1999 Jun; 18(2):231-9, 181. PMID: 10356355.
      Citations: 63     Fields:    Translation:AnimalsCells
    80. Maletic-Savatic M, Malinow R, Svoboda K. Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity. Science. 1999 Mar 19; 283(5409):1923-7. PMID: 10082466.
      Citations: 392     Fields:    Translation:AnimalsCells
    81. Maletic-Savatic M, Koothan T, Malinow R. Calcium-evoked dendritic exocytosis in cultured hippocampal neurons. Part II: mediation by calcium/calmodulin-dependent protein kinase II. J Neurosci. 1998 Sep 01; 18(17):6814-21. PMID: 9712652; PMCID: PMC6792974.
      Citations: 24     Fields:    Translation:AnimalsCells
    82. Maletic-Savatic M, Malinow R. Calcium-evoked dendritic exocytosis in cultured hippocampal neurons. Part I: trans-Golgi network-derived organelles undergo regulated exocytosis. J Neurosci. 1998 Sep 01; 18(17):6803-13. PMID: 9712651; PMCID: PMC6792980.
      Citations: 43     Fields:    Translation:AnimalsCells
    83. Maletic-Savatic M, Lenn NJ, Trimmer JS. Differential spatiotemporal expression of K+ channel polypeptides in rat hippocampal neurons developing in situ and in vitro. J Neurosci. 1995 May; 15(5 Pt 2):3840-51. PMID: 7751950; PMCID: PMC6578199.
      Citations: 112     Fields:    Translation:AnimalsCells
    84. Petrovchich I, Sosinsky A, Konde A, Archibald A, Henderson D, MALETIC-SAVATIC M, Milanovic S . Metabolomics in Schizophrenia and Major Depressive Disorder. 3(11):222-231. .
    85. Bielefeld P, Sierra A, Encinas JM, MALETIC-SAVATIC M, Anderson A. A, Fitzsimons CP. . Standardized Protocol for Stereotaxic Intrahippocampal Administration of Kainic Acid Combined with Electroencephalographic Seizure Monitoring in Mice. Front Neurosci. (11):160.
    86. MALETIC-SAVATIC M, Valenzuela M . Front Biol. Adult neurogenesis in Provence: Where history meets science. 3(11):149-150.
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