"Cullin Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of structurally related proteins that were originally discovered for their role in cell-cycle regulation in CAENORHABDITIS ELEGANS. They play important roles in regulation of the CELL CYCLE and as components of UBIQUITIN-PROTEIN LIGASES.
| Descriptor ID |
D044842
|
| MeSH Number(s) |
D08.811.464.938.750.750.500 D12.776.167.175
|
| Concept/Terms |
Cullin Proteins- Cullin Proteins
- Cullin Domain Proteins
- Cullins
- Cullin Domain Protein
- Cullin Protein
|
Below are MeSH descriptors whose meaning is more general than "Cullin Proteins".
Below are MeSH descriptors whose meaning is more specific than "Cullin Proteins".
This graph shows the total number of publications written about "Cullin Proteins" by people in this website by year, and whether "Cullin Proteins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 2 | 0 | 2 |
| 2006 | 2 | 1 | 3 |
| 2007 | 2 | 2 | 4 |
| 2008 | 3 | 2 | 5 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cullin Proteins" by people in Profiles.
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Genetic Susceptibility to Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis: The Missing Link? Am J Respir Cell Mol Biol. 2023 05; 68(5):482-484.
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ABL kinases regulate the stabilization of HIF-1a and MYC through?CPSF1. Proc Natl Acad Sci U S A. 2023 04 18; 120(16):e2210418120.
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The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes. Sci Rep. 2020 08 18; 10(1):13942.
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BIK ubiquitination by the E3 ligase Cul5-ASB11 determines cell fate during cellular stress. J Cell Biol. 2019 09 02; 218(9):3002-3018.
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A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation. Science. 2019 07 05; 365(6448).
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Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors. Nat Med. 2017 09; 23(9):1046-1054.
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Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation. Cancer Lett. 2017 01 28; 385:207-214.
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Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response. Mol Cell. 2015 Sep 03; 59(5):867-81.
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Hepatitis B virus HBx protein interactions with the ubiquitin proteasome system. Viruses. 2014 Nov 24; 6(11):4683-702.
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Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy. Antioxid Redox Signal. 2014 Dec 10; 21(17):2383-400.