"Cullin Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of structurally related proteins that were originally discovered for their role in cell-cycle regulation in CAENORHABDITIS ELEGANS. They play important roles in regulation of the CELL CYCLE and as components of UBIQUITIN-PROTEIN LIGASES.
| Descriptor ID |
D044842
|
| MeSH Number(s) |
D08.811.464.938.750.750.500 D12.776.167.175
|
| Concept/Terms |
Cullin Proteins- Cullin Proteins
- Cullin Domain Proteins
- Cullins
- Cullin Domain Protein
- Cullin Protein
|
Below are MeSH descriptors whose meaning is more general than "Cullin Proteins".
Below are MeSH descriptors whose meaning is more specific than "Cullin Proteins".
This graph shows the total number of publications written about "Cullin Proteins" by people in this website by year, and whether "Cullin Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cullin Proteins" by people in Profiles.
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Androgen receptor ubiquitination links KCTD13 to genitourinary tract defects. FASEB J. 2025 Feb 28; 39(4):e70406.
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Genetic Susceptibility to Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis: The Missing Link? Am J Respir Cell Mol Biol. 2023 05; 68(5):482-484.
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The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes. Sci Rep. 2020 08 18; 10(1):13942.
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Suppression of tumor angiogenesis by targeting the protein neddylation pathway. Cell Death Dis. 2014 Feb 13; 5:e1059.
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Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons. Neurology. 2014 Mar 11; 82(10):873-8.
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The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1. J Biol Chem. 2014 Feb 14; 289(7):4009-17.
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Identification of NUB1 as a suppressor of mutant Huntington toxicity via enhanced protein clearance. Nat Neurosci. 2013 May; 16(5):562-70.
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Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1. Oncogene. 2011 Oct 20; 30(42):4350-64.
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Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes. Cell Res. 2011 May; 21(5):754-69.
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A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Mol Cell Biol. 2010 Jul; 30(13):3275-85.