"NIMA-Related Kinase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A NIMA-related kinase that functions in CELL CYCLE regulation, the control of CILIA assembly, and CENTROSOME duplication. It is activated at G2 PHASE CELL CYCLE CHECKPOINTS in response to DNA DAMAGE.
| Descriptor ID |
D000072380
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.581.500 D12.776.167.457.500
|
| Concept/Terms |
NIMA-Related Kinase 1- NIMA-Related Kinase 1
- NIMA Related Kinase 1
- Nek1 Protein Kinase
- Kinase, Nek1 Protein
- Nek1 Kinase
- Kinase, Nek1
- NIMA-Related Protein Kinase 1
- NIMA Related Protein Kinase 1
|
Below are MeSH descriptors whose meaning is more general than "NIMA-Related Kinase 1".
Below are MeSH descriptors whose meaning is more specific than "NIMA-Related Kinase 1".
This graph shows the total number of publications written about "NIMA-Related Kinase 1" by people in this website by year, and whether "NIMA-Related Kinase 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "NIMA-Related Kinase 1" by people in Profiles.
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Nek1 regulates cell death and mitochondrial membrane permeability through phosphorylation of VDAC1. Cell Cycle. 2009 Jan 15; 8(2):257-67.
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PINA is essential for growth and positively influences NIMA function in Aspergillus nidulans. J Biol Chem. 2004 Jul 30; 279(31):32373-84.
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A new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization. Mol Biol Cell. 2003 Jan; 14(1):156-72.
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XCS-1, a maternally expressed gene product involved in regulating mitosis in Xenopus. J Cell Sci. 2000 Jul; 113 ( Pt 13):2497-505.
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Modulation of Xenopus oocyte-expressed phospholemman-induced ion currents by co-expression of protein kinases. Biochim Biophys Acta. 1999 Sep 21; 1451(2-3):305-18.
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Expression of a constitutively active Ca2+/calmodulin-dependent kinase in Aspergillus nidulans spores prevents germination and entry into the cell cycle. J Biol Chem. 1997 Feb 07; 272(6):3223-30.
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Expression of the noncatalytic domain of the NIMA kinase causes a G2 arrest in Aspergillus nidulans. EMBO J. 1994 May 01; 13(9):2103-13.
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Identification of substrate specificity determinants for the cell cycle-regulated NIMA protein kinase. J Biol Chem. 1994 Mar 04; 269(9):6603-7.
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Properties and regulation of the cell cycle-specific NIMA protein kinase of Aspergillus nidulans. J Biol Chem. 1993 Apr 25; 268(12):8769-76.