G-Protein-Coupled Receptor Kinases
"G-Protein-Coupled Receptor Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of serine-threonine kinases that are specific for G-PROTEIN-COUPLED RECEPTORS. They are regulatory proteins that play a role in G-protein-coupled receptor densensitization.
| Descriptor ID |
D054768
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.364 D12.644.360.293 D12.776.476.293
|
| Concept/Terms |
G-Protein-Coupled Receptor Kinases- G-Protein-Coupled Receptor Kinases
- G Protein Coupled Receptor Kinases
- Kinases, G-Protein-Coupled Receptor
- Receptor Kinases, G-Protein-Coupled
|
Below are MeSH descriptors whose meaning is more general than "G-Protein-Coupled Receptor Kinases".
Below are MeSH descriptors whose meaning is more specific than "G-Protein-Coupled Receptor Kinases".
This graph shows the total number of publications written about "G-Protein-Coupled Receptor Kinases" by people in this website by year, and whether "G-Protein-Coupled Receptor Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "G-Protein-Coupled Receptor Kinases" by people in Profiles.
-
Inhibition of G Protein-Coupled Receptor Kinase 2 Promotes Unbiased Downregulation of IGF1 Receptor and Restrains Malignant Cell Growth. Cancer Res. 2021 01 15; 81(2):501-514.
-
The association of single-nucleotide polymorphisms in the?oxytocin receptor and G protein-coupled receptor kinase 6 (GRK6) genes with oxytocin dosing requirements and labor outcomes. Am J Obstet Gynecol. 2017 09; 217(3):367.e1-367.e9.
-
G protein-coupled receptor kinase 6 acts as a critical regulator of cytokine-induced hyperalgesia by promoting phosphatidylinositol 3-kinase and inhibiting p38 signaling. Mol Med. 2012 May 09; 18:556-64.
-
Potential dopamine-1 receptor stimulation in hypertension management. Curr Hypertens Rep. 2011 Aug; 13(4):294-302.
-
Mutating the dileucine motif of the human beta(2)-adrenoceptor reduces the high initial rate of receptor phosphorylation by GRK without affecting postendocytic sorting. Eur J Pharmacol. 2010 Jun 10; 635(1-3):9-15.
-
Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation. Mol Pharmacol. 2010 Mar; 77(3):405-15.
-
G protein-coupled receptor kinase 6 controls post-inflammatory visceral hyperalgesia. Brain Behav Immun. 2009 Jan; 23(1):18-26.
-
G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice. Gut. 2007 Jun; 56(6):847-54.
-
Knock-out mice reveal the contributions of P2Y and P2X receptors to nucleotide-induced Ca2+ signaling in macrophages. J Biol Chem. 2006 Nov 17; 281(46):35147-55.
-
beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. J Biol Chem. 2006 Jan 13; 281(2):1261-73.