Receptor, Angiotensin, Type 1
"Receptor, Angiotensin, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An angiotensin receptor subtype that is expressed at high levels in a variety of adult tissues including the CARDIOVASCULAR SYSTEM, the KIDNEY, the ENDOCRINE SYSTEM and the NERVOUS SYSTEM. Activation of the type 1 angiotensin receptor causes VASOCONSTRICTION and sodium retention.
| Descriptor ID |
D044140
|
| MeSH Number(s) |
D12.776.543.750.695.047.625 D12.776.543.750.750.130.750
|
| Concept/Terms |
Receptor, Angiotensin, Type 1- Receptor, Angiotensin, Type 1
- Angiotensin II Type 1 Receptor
- Angiotensin AT1 Receptor
- AT1 Receptor, Angiotensin
- Receptor, Angiotensin AT1
- Angiotensin Type 1 Receptor
- Receptor, Angiotensin II Type 1
Receptor, Angiotensin, Type 1b- Receptor, Angiotensin, Type 1b
- Angiotensin II Type 1b Receptor
- Angiotensin Type 1b Receptor
- Angiotensin AT1b Receptor
- AT1b Receptor, Angiotensin
- Receptor, Angiotensin AT1b
- Receptor, Angiotensin II Type 1b
Receptor, Angiotensin, Type 1a- Receptor, Angiotensin, Type 1a
- Angiotensin II Type 1a Receptor
- Angiotensin AT1a Receptor
- AT1a Receptor, Angiotensin
- Receptor, Angiotensin AT1a
- Angiotensin Type 1a Receptor
- Receptor, Angiotensin II Type 1a
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Angiotensin, Type 1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Angiotensin [D12.776.543.750.695.047]
- Receptor, Angiotensin, Type 1 [D12.776.543.750.695.047.625]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Angiotensin [D12.776.543.750.750.130]
- Receptor, Angiotensin, Type 1 [D12.776.543.750.750.130.750]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Angiotensin, Type 1".
This graph shows the total number of publications written about "Receptor, Angiotensin, Type 1" by people in this website by year, and whether "Receptor, Angiotensin, Type 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 4 | 4 |
| 2004 | 1 | 3 | 4 |
| 2005 | 1 | 2 | 3 |
| 2006 | 2 | 1 | 3 |
| 2007 | 1 | 2 | 3 |
| 2008 | 3 | 1 | 4 |
| 2009 | 0 | 1 | 1 |
| 2010 | 3 | 1 | 4 |
| 2011 | 4 | 5 | 9 |
| 2012 | 3 | 1 | 4 |
| 2013 | 1 | 0 | 1 |
| 2014 | 3 | 3 | 6 |
| 2015 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Angiotensin, Type 1" by people in Profiles.
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Nanobody-Mediated Dualsteric Engagement of the Angiotensin Receptor Broadens Biased Ligand Pharmacology. Mol Pharmacol. 2024 Feb 15; 105(3):260-271.
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DNA demethylation in the hypothalamus promotes transcription of Agtr1a and Slc12a2 and hypertension development. J Biol Chem. 2024 Feb; 300(2):105597.
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Angiotensin II type 2 receptor activation preserves megalin in the kidney and prevents proteinuria in high salt diet fed rats. Sci Rep. 2023 03 15; 13(1):4277.
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The Angiotensin AT2 Receptor: From a Binding Site to a Novel Therapeutic Target. Pharmacol Rev. 2022 10; 74(4):1051-1135.
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Sorting nexin 1 loss results in increased oxidative stress and hypertension. FASEB J. 2020 06; 34(6):7941-7957.
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Exploring the Evidence Implicating the Renin-Angiotensin System (RAS) in the Physiopathology of Mood Disorders. Protein Pept Lett. 2020; 27(6):449-455.
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Endogenous AT1 receptor-protein kinase C activity in the hypothalamus augments glutamatergic input and sympathetic outflow in hypertension. J Physiol. 2019 08; 597(16):4325-4340.
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Superoxide via Sp3 mechanism increases renal renin activity, renal AT1 receptor function, and blood pressure in rats. Am J Physiol Renal Physiol. 2018 11 01; 315(5):F1478-F1483.
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Dimerization of AT2 and Mas Receptors in Control of Blood Pressure. Curr Hypertens Rep. 2018 05 01; 20(5):41.
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Role of AT2R (Angiotensin Type 2 Receptor) in Maintaining Sodium-Potassium Balance. Hypertension. 2018 04; 71(4):563-565.