Dual-Specificity Phosphatases
"Dual-Specificity Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sub-class of protein tyrosine phosphatases that contain an additional phosphatase activity which cleaves phosphate ester bonds on SERINE or THREONINE residues that are located on the same protein.
| Descriptor ID |
D054637
|
| MeSH Number(s) |
D08.811.277.352.650.625.225 D08.811.277.352.650.775.250 D08.811.641.755 D12.644.360.268 D12.776.476.268
|
| Concept/Terms |
Dual-Specificity Phosphatases- Dual-Specificity Phosphatases
- Dual Specificity Phosphatases
- Phosphatases, Dual-Specificity
- Dual-Specificity Phosphatase
- Dual Specificity Phosphatase
- Phosphatase, Dual-Specificity
- DUSP Phosphatases
- Phosphatases, DUSP
|
Below are MeSH descriptors whose meaning is more general than "Dual-Specificity Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "Dual-Specificity Phosphatases".
This graph shows the total number of publications written about "Dual-Specificity Phosphatases" by people in this website by year, and whether "Dual-Specificity Phosphatases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 2 | 3 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 2 | 0 | 2 |
| 2016 | 3 | 0 | 3 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Dual-Specificity Phosphatases" by people in Profiles.
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DUSP22 rearrangement is associated with a distinctive immunophenotype but not outcome in patients with systemic ALK-negative anaplastic large cell lymphoma. Haematologica. 2023 06 01; 108(6):1604-1615.
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Lymphomatoid papulosis with DUSP22-IRF4 rearrangement: A case report and literature review. J Cutan Pathol. 2023 Aug; 50(8):711-716.
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Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability. Int J Mol Sci. 2019 May 30; 20(11).
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Fragment-based design, synthesis, biological evaluation, and SAR of 1H-benzo[d]imidazol-2-yl)-1H-indazol derivatives as potent PDK1 inhibitors. Bioorg Med Chem Lett. 2017 12 15; 27(24):5473-5480.
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Downregulation of the phosphatase JKAP/DUSP22 in T cells as a potential new biomarker of systemic lupus erythematosus nephritis. Oncotarget. 2016 Sep 06; 7(36):57593-57605.
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Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 and Rotavirus Antigen VP6. J Immunol. 2016 08 15; 197(4):1065-73.
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Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion. Breast Cancer Res Treat. 2016 08; 158(3):441-54.
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Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse. PLoS Genet. 2016 Apr; 12(4):e1005970.
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TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity. Cell Signal. 2016 Jan; 28(1):145-51.
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Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair. Mol Cell Biol. 2015 Nov; 35(21):3657-68.