Dual-Specificity Phosphatases
"Dual-Specificity Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sub-class of protein tyrosine phosphatases that contain an additional phosphatase activity which cleaves phosphate ester bonds on SERINE or THREONINE residues that are located on the same protein.
| Descriptor ID |
D054637
|
| MeSH Number(s) |
D08.811.277.352.650.625.225 D08.811.277.352.650.775.250 D08.811.641.755 D12.644.360.268 D12.776.476.268
|
| Concept/Terms |
Dual-Specificity Phosphatases- Dual-Specificity Phosphatases
- Dual Specificity Phosphatases
- Phosphatases, Dual-Specificity
- Dual-Specificity Phosphatase
- Dual Specificity Phosphatase
- Phosphatase, Dual-Specificity
- DUSP Phosphatases
- Phosphatases, DUSP
|
Below are MeSH descriptors whose meaning is more general than "Dual-Specificity Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "Dual-Specificity Phosphatases".
This graph shows the total number of publications written about "Dual-Specificity Phosphatases" by people in this website by year, and whether "Dual-Specificity Phosphatases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 3 | 0 | 3 |
| 2016 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dual-Specificity Phosphatases" by people in Profiles.
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NSC 95397 Suppresses Proliferation and Induces Apoptosis in Colon Cancer Cells through MKP-1 and the ERK1/2 Pathway. Int J Mol Sci. 2018 May 31; 19(6).
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Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 and Rotavirus Antigen VP6. J Immunol. 2016 08 15; 197(4):1065-73.
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Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion. Breast Cancer Res Treat. 2016 08; 158(3):441-54.
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Overexpression of major CDKN3 transcripts is associated with poor survival in lung adenocarcinoma. Br J Cancer. 2015 Dec 22; 113(12):1735-43.
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Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair. Mol Cell Biol. 2015 Nov; 35(21):3657-68.
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NSC-87877 inhibits DUSP26 function in neuroblastoma resulting in p53-mediated apoptosis. Cell Death Dis. 2015 Aug 06; 6:e1841.
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NADPH oxidase-generated reactive oxygen species are required for stromal cell-derived factor-1a-stimulated angiogenesis. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2023-32.
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The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck. Nat Commun. 2014 Apr 09; 5:3618.
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MAPK phosphotase 5 deficiency contributes to protection against blood-stage Plasmodium yoelii 17XL infection in mice. J Immunol. 2014 Apr 15; 192(8):3686-96.
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Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk. Carcinogenesis. 2013 Apr; 34(4):885-92.