Protein Tyrosine Phosphatases
"Protein Tyrosine Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
| Descriptor ID |
D017027
|
| MeSH Number(s) |
D08.811.277.352.650.775
|
| Concept/Terms |
Protein Tyrosine Phosphatases- Protein Tyrosine Phosphatases
- Phosphatases, Protein Tyrosine
- Tyrosine Phosphatases, Protein
- Phosphotyrosyl Protein Phosphatase
- Phosphatase, Phosphotyrosyl Protein
- Protein Phosphatase, Phosphotyrosyl
- Protein-Tyrosine Phosphatase
- Phosphatase, Protein-Tyrosine
- PTPase
- Tyrosyl Phosphoprotein Phosphatase
- Phosphatase, Tyrosyl Phosphoprotein
- Phosphoprotein Phosphatase, Tyrosyl
- Phosphotyrosine Phosphatase
- Phosphatase, Phosphotyrosine
- Protein-Tyrosine-Phosphatase
- Protein Tyrosine Phosphatase
|
Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatases".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatases" by people in this website by year, and whether "Protein Tyrosine Phosphatases" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 1 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 2 | 0 | 2 |
| 2004 | 6 | 1 | 7 |
| 2005 | 4 | 4 | 8 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 1 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Tyrosine Phosphatases" by people in Profiles.
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Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy. Sci Adv. 2024 Feb 02; 10(5):eadg7887.
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A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3. Am J Hum Genet. 2024 01 04; 111(1):96-118.
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Reevaluation of the role of LIP-1 as an ERK/MPK-1 dual specificity phosphatase in the C. elegans germline. Proc Natl Acad Sci U S A. 2022 01 18; 119(3).
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Altered nociception in Alzheimer disease is associated with striatal-enriched protein tyrosine phosphatase signaling. Pain. 2021 06 01; 162(6):1669-1680.
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Yersinia pseudotuberculosis YopE prevents uptake by M cells and instigates M cell extrusion in human ileal enteroid-derived monolayers. Gut Microbes. 2021 Jan-Dec; 13(1):1988390.
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Prolyl Hydroxylase Domain-2 Protein Regulates Lipopolysaccharide-Induced Vascular Inflammation. Am J Pathol. 2019 01; 189(1):200-213.
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Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma. Cell Rep. 2017 Dec 05; 21(10):2772-2784.
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A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Nature. 2017 12 14; 552(7684):258-262.
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Molecular Pathways: Targeting Protein Tyrosine Phosphatases in Cancer. Clin Cancer Res. 2017 May 01; 23(9):2136-2142.
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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. J Am Soc Nephrol. 2017 Mar; 28(3):981-994.