"Intellectual Disability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Descriptor ID |
D008607
|
| MeSH Number(s) |
C10.597.606.643 C23.888.592.604.646 F01.700.687 F03.625.539
|
| Concept/Terms |
Intellectual Disability- Intellectual Disability
- Disabilities, Intellectual
- Intellectual Disabilities
- Retardation, Mental
- Mental Retardation
- Disability, Intellectual
- Intellectual Development Disorder
- Development Disorder, Intellectual
- Development Disorders, Intellectual
- Disorder, Intellectual Development
- Disorders, Intellectual Development
- Intellectual Development Disorders
Mental Retardation, Psychosocial- Mental Retardation, Psychosocial
- Mental Retardations, Psychosocial
- Psychosocial Mental Retardation
- Psychosocial Mental Retardations
- Retardation, Psychosocial Mental
- Retardations, Psychosocial Mental
Deficiency, Mental- Deficiency, Mental
- Deficiencies, Mental
- Mental Deficiencies
- Mental Deficiency
|
Below are MeSH descriptors whose meaning is more general than "Intellectual Disability".
Below are MeSH descriptors whose meaning is more specific than "Intellectual Disability".
This graph shows the total number of publications written about "Intellectual Disability" by people in this website by year, and whether "Intellectual Disability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 5 | 1 | 6 |
| 1997 | 0 | 1 | 1 |
| 1998 | 5 | 1 | 6 |
| 1999 | 2 | 2 | 4 |
| 2000 | 5 | 0 | 5 |
| 2001 | 3 | 1 | 4 |
| 2002 | 7 | 1 | 8 |
| 2003 | 4 | 2 | 6 |
| 2004 | 3 | 4 | 7 |
| 2005 | 8 | 4 | 12 |
| 2006 | 6 | 2 | 8 |
| 2007 | 12 | 3 | 15 |
| 2008 | 3 | 3 | 6 |
| 2009 | 6 | 3 | 9 |
| 2010 | 7 | 4 | 11 |
| 2011 | 6 | 2 | 8 |
| 2012 | 10 | 9 | 19 |
| 2013 | 10 | 5 | 15 |
| 2014 | 8 | 1 | 9 |
| 2015 | 11 | 0 | 11 |
| 2016 | 21 | 6 | 27 |
| 2017 | 18 | 5 | 23 |
| 2018 | 16 | 8 | 24 |
| 2019 | 25 | 8 | 33 |
| 2020 | 23 | 8 | 31 |
| 2021 | 31 | 8 | 39 |
| 2022 | 33 | 1 | 34 |
| 2023 | 30 | 0 | 30 |
| 2024 | 14 | 12 | 26 |
| 2025 | 5 | 6 | 11 |
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Below are the most recent publications written about "Intellectual Disability" by people in Profiles.
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Recurrent de novo variants in the spliceosomal factor CRNKL1 are associated with severe microcephaly and pontocerebellar hypoplasia with seizures. Am J Hum Genet. 2025 Jul 03; 112(7):1722-1732.
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Evaluating the consistency of SMARCB1 variant classification and assertions of genotype-phenotype relationships in ClinVar. Cancer Genet. 2025 Sep; 296-297:84-87.
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Rest-activity rhythm phenotypes in adults with epilepsy and intellectual disability. Epilepsia Open. 2025 Aug; 10(4):1086-1098.
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Loss of function of the zinc finger homeobox 4 gene, ZFHX4, underlies a neurodevelopmental disorder. Am J Hum Genet. 2025 Jun 05; 112(6):1388-1414.
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Bi-allelic pathogenic variants in TRMT1 disrupt tRNA modification and induce a neurodevelopmental disorder. Am J Hum Genet. 2025 May 01; 112(5):1117-1138.
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Neuroanatomical features of NAA10 and NAA15-related neurodevelopmental syndromes. J Neuroradiol. 2025 Jun; 52(4):101339.
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De novo variants in CDKL1 and CDKL2 are associated with neurodevelopmental symptoms. Am J Hum Genet. 2025 Apr 03; 112(4):846-862.
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Unraveling the Molecular and Clinical Consequences of an Intragenic TRIP12 Duplication Using Genomic and RNA Analyses. Am J Med Genet A. 2025 Jul; 197(7):e64036.
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Expanded Clinical Phenotype and the Role of Untargeted Metabolomics Analysis in Confirming the Diagnosis of Sodium-Dependent Multivitamin Transporter Deficiency. Am J Med Genet A. 2025 Jun; 197(6):e64014.
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Bi-allelic KICS2 mutations impair KICSTOR complex-mediated mTORC1 regulation, causing intellectual disability and epilepsy. Am J Hum Genet. 2025 Feb 06; 112(2):374-393.