"Anhedonia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).
| Descriptor ID |
D059445
|
| MeSH Number(s) |
C10.597.606.057 C23.888.592.604.039 F01.700.039
|
| Concept/Terms |
Social Anhedonia- Social Anhedonia
- Anhedonia, Social
- Anhedonias, Social
- Social Anhedonias
Physical Anhedonia- Physical Anhedonia
- Anhedonia, Physical
- Anhedonias, Physical
- Physical Anhedonias
|
Below are MeSH descriptors whose meaning is more general than "Anhedonia".
Below are MeSH descriptors whose meaning is more specific than "Anhedonia".
This graph shows the total number of publications written about "Anhedonia" by people in this website by year, and whether "Anhedonia" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 2 | 2 |
| 2025 | 3 | 2 | 5 |
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Below are the most recent publications written about "Anhedonia" by people in Profiles.
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A Phase 2 Randomized Trial of NBI-1065846 (TAK-041) in Patients With Anhedonia Associated With Major Depressive Disorder: Results of the TERPSIS Study. J Clin Psychopharmacol. 2025 Sep-Oct 01; 45(5):432-440.
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The effect of adjunctive cariprazine on symptoms of anhedonia in patients with major depressive disorder. J Affect Disord. 2025 Sep 15; 385:119366.
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Affective temperament modulates the relationship between physical and psychiatric symptoms during long-COVID: results from the Gemelli against COVID-19 post-acute care service. J Affect Disord. 2025 Aug 15; 383:315-322.
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Effects of KCNQ potassium channel modulation on ventral tegmental area activity and connectivity in individuals with depression and anhedonia. Mol Psychiatry. 2025 Aug; 30(8):3686-3694.
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Effects of the KCNQ (Kv7) Channel Opener Ezogabine on Resting-State Functional Connectivity of Striatal Brain Reward Regions, Depression, and Anhedonia in Major Depressive Disorder: Results From a Randomized Controlled Trial. Biol Psychiatry. 2025 Oct 01; 98(7):568-577.
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Dopaminergic dysfunction in the left putamen of patients with major depressive disorder. J Affect Disord. 2024 07 15; 357:107-115.
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The clinical presentation of major depressive disorder in youth with co-occurring obsessive-compulsive disorder. J Affect Disord. 2024 03 15; 349:349-357.
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Using latent profile analyses to classify subjects with anhedonia based on reward-related measures obtained in the FAST-MAS study. J Affect Disord. 2023 10 15; 339:584-592.
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A Participant-Level Integrative Data Analysis of Differential Placebo Response for Suicidal Ideation and Nonsuicidal Depressive Symptoms in Clinical Trials of Intravenous Racemic Ketamine. Int J Neuropsychopharmacol. 2022 10 25; 25(10):827-838.
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White matter microstructure associated with anhedonia among individuals with bipolar disorders and high-risk for bipolar disorders. J Affect Disord. 2022 03 01; 300:91-98.