"Ketamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
| Descriptor ID |
D007649
|
| MeSH Number(s) |
D02.455.426.392.368.367.652
|
| Concept/Terms |
Ketamine- Ketamine
- 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
|
Below are MeSH descriptors whose meaning is more general than "Ketamine".
Below are MeSH descriptors whose meaning is more specific than "Ketamine".
This graph shows the total number of publications written about "Ketamine" by people in this website by year, and whether "Ketamine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 5 | 0 | 5 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 2 | 3 |
| 2008 | 2 | 0 | 2 |
| 2009 | 3 | 1 | 4 |
| 2010 | 3 | 0 | 3 |
| 2011 | 3 | 0 | 3 |
| 2012 | 5 | 1 | 6 |
| 2013 | 3 | 0 | 3 |
| 2014 | 4 | 2 | 6 |
| 2015 | 9 | 0 | 9 |
| 2016 | 2 | 0 | 2 |
| 2017 | 5 | 1 | 6 |
| 2018 | 7 | 1 | 8 |
| 2019 | 9 | 1 | 10 |
| 2020 | 14 | 0 | 14 |
| 2021 | 7 | 0 | 7 |
| 2022 | 20 | 0 | 20 |
| 2023 | 16 | 0 | 16 |
| 2024 | 8 | 0 | 8 |
| 2025 | 6 | 0 | 6 |
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Below are the most recent publications written about "Ketamine" by people in Profiles.
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Comparing the Cognitive Effects of Repeated Intravenous Ketamine and Electroconvulsive Therapy in Patients With Treatment-Resistant Depression: A Secondary Analysis of the ELEKT-D Trial. J Clin Psychiatry. 2025 Sep 03; 86(4).
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Comparing the effects of ECT and intravenous ketamine in psychiatric patients with major depressive episodes. J Affect Disord. 2025 Nov 15; 389:119727.
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Lessons learned from the regulatory alignment in ketamine, esketamine and arketamine clinical trials: A cross-sectional analysis of protocols from ClinicalTrials.gov. Psychiatry Res. 2025 Aug; 350:116559.
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Lack of relationships between ketamine treatment and peripheral neurotrophic and inflammatory factors in a randomized controlled ketamine trial of major depressive disorder. Brain Behav Immun. 2025 Aug; 128:170-178.
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Patient preference effects in a randomized comparative effectiveness study of electroconvulsive therapy and ketamine for treatment resistant depression: An ELEKT-D trial secondary analysis. Psychiatry Res. 2025 May; 347:116411.
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A randomized, placebo-controlled, cross-over trial of ketamine in Rett syndrome. J Neurodev Disord. 2025 Jan 24; 17(1):4.
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Fentanyl versus nebulized ketamine for prehospital analgesia: A retrospective data review. Am J Emerg Med. 2025 Mar; 89:124-128.
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Ketamine induces plasticity in a norepinephrine-astroglial circuit to promote behavioral perseverance. Neuron. 2025 Feb 05; 113(3):426-443.e5.
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Functional connectivity subtypes during a positive mood induction: Predicting clinical response in a randomized controlled trial of ketamine for treatment-resistant depression. J Psychopathol Clin Sci. 2025 Apr; 134(3):228-238.
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Interventional approaches to treatment resistant depression (DTR) in children and adolescents: A systematic review and meta-analysis. J Affect Disord. 2024 Dec 15; 367:519-529.