"Acetyl-CoA Carboxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A carboxylating enzyme that catalyzes the conversion of ATP, acetyl-CoA, and HCO3- to ADP, orthophosphate, and malonyl-CoA. It is a biotinyl-protein that also catalyzes transcarboxylation. The plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA (From Enzyme Nomenclature, 1992) EC 6.4.1.2.
| Descriptor ID |
D000103
|
| MeSH Number(s) |
D08.811.464.257.050 D08.811.641.249
|
| Concept/Terms |
Acetyl-CoA Carboxylase- Acetyl-CoA Carboxylase
- Acetyl CoA Carboxylase
- Carboxylase, Acetyl-CoA
- Acetyl Coenzyme A Carboxylase
|
Below are MeSH descriptors whose meaning is more general than "Acetyl-CoA Carboxylase".
Below are MeSH descriptors whose meaning is more specific than "Acetyl-CoA Carboxylase".
This graph shows the total number of publications written about "Acetyl-CoA Carboxylase" by people in this website by year, and whether "Acetyl-CoA Carboxylase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Acetyl-CoA Carboxylase" by people in Profiles.
-
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism. Nat Commun. 2024 May 14; 15(1):4083.
-
Chloroflexus aurantiacus acetyl-CoA carboxylase evolves fused biotin carboxylase and biotin carboxyl carrier protein to complete carboxylation activity. mBio. 2024 May 08; 15(5):e0341423.
-
Translational control of lipogenesis links protein synthesis and phosphoinositide signaling with nuclear division in Saccharomyces cerevisiae. Genetics. 2022 Jan 04; 220(1).
-
Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer. Cell Rep Med. 2021 12 21; 2(12):100471.
-
WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis. J Clin Invest. 2021 08 16; 131(16).
-
Blood meal drives de novo lipogenesis in the fat body of Rhodnius prolixus. Insect Biochem Mol Biol. 2021 06; 133:103511.
-
Energy-stress-mediated AMPK activation inhibits ferroptosis. Nat Cell Biol. 2020 02; 22(2):225-234.
-
Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma. Cell Metab. 2019 01 08; 29(1):174-182.e5.
-
Circulating Biomarkers From the Phase 1 Trial of Sirolimus and Autophagy Inhibition for Patients With Lymphangioleiomyomatosis. Chest. 2018 11; 154(5):1070-1082.
-
A revised model for the control of fatty acid synthesis by master regulator Spo0A in Bacillus subtilis. Mol Microbiol. 2018 05; 108(4):424-442.