"Netrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of extracellular proteins that are related structurally to LAMININ. They function as CHEMOTACTIC FACTORS for CELL MIGRATION and AXON GUIDANCE, acting as chemoattractants for some cell types, and as chemorepellents for others.
| Descriptor ID |
D000075385
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| MeSH Number(s) |
D12.644.276.860.494 D12.776.467.860.494 D12.776.631.600.494 D12.776.860.300.731 D23.125.842 D23.529.850.494
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Netrins".
Below are MeSH descriptors whose meaning is more specific than "Netrins".
This graph shows the total number of publications written about "Netrins" by people in this website by year, and whether "Netrins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Netrins" by people in Profiles.
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Bexarotene normalizes chemotherapy-induced myelin decompaction and reverses cognitive and sensorimotor deficits in mice. Acta Neuropathol Commun. 2020 11 12; 8(1):193.
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Homozygous Missense Variants in NTNG2, Encoding a Presynaptic Netrin-G2 Adhesion Protein, Lead to a Distinct Neurodevelopmental Disorder. Am J Hum Genet. 2019 11 07; 105(5):1048-1056.
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Identification of new netrin family members in zebrafish: developmental expression of netrin 2 and netrin 4. Dev Dyn. 2005 Nov; 234(3):726-31.
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Netrins and neogenin promote myotube formation. J Cell Biol. 2004 Nov 08; 167(3):493-504.
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Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors. J Neurosci. 1999 Jun 15; 19(12):4938-47.
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The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell. 1994 Aug 12; 78(3):409-24.