"Osteopontin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negatively-charged extracellular matrix protein that plays a role in the regulation of BONE metabolism and a variety of other biological functions. Cell signaling by osteopontin may occur through a cell adhesion sequence that recognizes INTEGRIN ALPHA-V BETA-3.
| Descriptor ID |
D053495
|
| MeSH Number(s) |
D12.644.276.374.625 D12.776.395.700.837 D12.776.467.374.625 D12.776.860.300.762 D23.529.374.625
|
| Concept/Terms |
Osteopontin- Osteopontin
- Sialoprotein 1
- Secreted Phosphoprotein 1
- Bone Sialoprotein 1
- Sialoprotein 1, Bone
- Bone Sialoprotein I
- Sialoprotein I, Bone
|
Below are MeSH descriptors whose meaning is more general than "Osteopontin".
Below are MeSH descriptors whose meaning is more specific than "Osteopontin".
This graph shows the total number of publications written about "Osteopontin" by people in this website by year, and whether "Osteopontin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 5 | 5 |
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 4 | 4 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 9 | 9 |
| 2006 | 0 | 4 | 4 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 3 | 0 | 3 |
| 2010 | 2 | 2 | 4 |
| 2011 | 3 | 2 | 5 |
| 2012 | 3 | 1 | 4 |
| 2013 | 1 | 0 | 1 |
| 2014 | 3 | 2 | 5 |
| 2015 | 1 | 2 | 3 |
| 2016 | 3 | 1 | 4 |
| 2017 | 0 | 3 | 3 |
| 2018 | 3 | 0 | 3 |
| 2019 | 0 | 2 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Osteopontin" by people in Profiles.
-
Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma. Cancer Cell. 2019 06 10; 35(6):868-884.e6.
-
Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade. Gut. 2019 09; 68(9):1653-1666.
-
Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target. J Clin Invest. 2019 01 02; 129(1):137-149.
-
Different effects of global osteopontin and macrophage osteopontin in glomerular injury. Am J Physiol Renal Physiol. 2018 10 01; 315(4):F759-F768.
-
CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH-associated neurodegeneration and mass lesions. Cancer. 2018 06 15; 124(12):2607-2620.
-
Prospective Validation of Molecular Prognostic Markers in Cutaneous Melanoma: A Correlative Analysis of E1690. Clin Cancer Res. 2017 Nov 15; 23(22):6888-6892.
-
Integrating cytokines and angiogenic factors and tumour bulk with selected clinical criteria improves determination of prognosis in advanced renal cell carcinoma. Br J Cancer. 2017 Aug 08; 117(4):478-484.
-
The value of biomarkers in bone metastasis. Eur J Cancer Care (Engl). 2017 Nov; 26(6).
-
Plasma Surfactant Protein-D, Matrix Metalloproteinase-7, and Osteopontin Index Distinguishes Idiopathic Pulmonary Fibrosis from Other Idiopathic Interstitial Pneumonias. Am J Respir Crit Care Med. 2016 11 15; 194(10):1242-1251.
-
Association Study of Exon Variants in the NF-?B and TGF? Pathways Identifies CD40 as a Modifier of Duchenne Muscular Dystrophy. Am J Hum Genet. 2016 Nov 03; 99(5):1163-1171.