Leukemia Inhibitory Factor
"Leukemia Inhibitory Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
| Descriptor ID |
D053605
|
| MeSH Number(s) |
D12.644.276.374.470 D12.776.467.374.470 D23.529.374.470
|
| Concept/Terms |
Leukemia Inhibitory Factor- Leukemia Inhibitory Factor
- Inhibitory Factor, Leukemia
- Differentiation-Stimulating Factor
- Differentiation Stimulating Factor
- D Factor (Leukemia Inhibitory Factor)
- Myeloid Differentiation-Stimulating Factor
- Differentiation-Stimulating Factor, Myeloid
- Myeloid Differentiation Stimulating Factor
- Cholinergic Differentiation Factor
- Differentiation Factor, Cholinergic
|
Below are MeSH descriptors whose meaning is more general than "Leukemia Inhibitory Factor".
Below are MeSH descriptors whose meaning is more specific than "Leukemia Inhibitory Factor".
This graph shows the total number of publications written about "Leukemia Inhibitory Factor" by people in this website by year, and whether "Leukemia Inhibitory Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukemia Inhibitory Factor" by people in Profiles.
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The uterine secretome initiates growth of gynecologic tissues in ectopic locations. PLoS One. 2024; 19(5):e0292978.
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Dismantling the tumoral cloak of self-protection. PLoS Biol. 2023 05; 21(5):e3002104.
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Estrogen receptor a (ERa)-binding super-enhancers drive key mediators that control uterine estrogen responses in mice. J Biol Chem. 2020 06 19; 295(25):8387-8400.
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SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh. Nat Commun. 2018 10 24; 9(1):4421.
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Forkhead box a2 (FOXA2) is essential for uterine function and fertility. Proc Natl Acad Sci U S A. 2017 02 07; 114(6):E1018-E1026.
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Retinal Caveolin-1 Modulates Neuroprotective Signaling. Adv Exp Med Biol. 2016; 854:411-8.
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Embryonic Stem Cell Growth Factors Regulate eIF2a Phosphorylation. PLoS One. 2015; 10(9):e0139076.
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LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers. Nat Commun. 2014 Oct 17; 5:5218.
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The death-inducer obliterator 1 (Dido1) gene regulates embryonic stem cell self-renewal. J Biol Chem. 2014 Feb 21; 289(8):4778-86.
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STAT3 regulates uterine epithelial remodeling and epithelial-stromal crosstalk during implantation. Mol Endocrinol. 2013 Dec; 27(12):1996-2012.