Leukemia Inhibitory Factor
"Leukemia Inhibitory Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
| Descriptor ID |
D053605
|
| MeSH Number(s) |
D12.644.276.374.470 D12.776.467.374.470 D23.529.374.470
|
| Concept/Terms |
Leukemia Inhibitory Factor- Leukemia Inhibitory Factor
- Inhibitory Factor, Leukemia
- Differentiation-Stimulating Factor
- Differentiation Stimulating Factor
- D Factor (Leukemia Inhibitory Factor)
- Myeloid Differentiation-Stimulating Factor
- Differentiation-Stimulating Factor, Myeloid
- Myeloid Differentiation Stimulating Factor
- Cholinergic Differentiation Factor
- Differentiation Factor, Cholinergic
|
Below are MeSH descriptors whose meaning is more general than "Leukemia Inhibitory Factor".
Below are MeSH descriptors whose meaning is more specific than "Leukemia Inhibitory Factor".
This graph shows the total number of publications written about "Leukemia Inhibitory Factor" by people in this website by year, and whether "Leukemia Inhibitory Factor" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukemia Inhibitory Factor" by people in Profiles.
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Progesterone receptor in uterine glands is required for pregnancy establishment in mice. FASEB J. 2025 Mar 31; 39(6):e70495.
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Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis. Proc Natl Acad Sci U S A. 2024 Dec 10; 121(50):e2401899121.
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The uterine secretome initiates growth of gynecologic tissues in ectopic locations. PLoS One. 2024; 19(5):e0292978.
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Estrogen receptor a (ERa)-binding super-enhancers drive key mediators that control uterine estrogen responses in mice. J Biol Chem. 2020 06 19; 295(25):8387-8400.
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SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh. Nat Commun. 2018 10 24; 9(1):4421.
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Forkhead box a2 (FOXA2) is essential for uterine function and fertility. Proc Natl Acad Sci U S A. 2017 02 07; 114(6):E1018-E1026.
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Innate Stat3-mediated induction of the antimicrobial protein Reg3? is required for host defense against MRSA pneumonia. J Exp Med. 2013 Mar 11; 210(3):551-61.
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Paracrine signalling events in embryonic stem cell renewal mediated by affinity targeted nanoparticles. Biomaterials. 2012 Oct; 33(28):6634-43.
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Conditional deletion of Msx homeobox genes in the uterus inhibits blastocyst implantation by altering uterine receptivity. Dev Cell. 2011 Dec 13; 21(6):1014-25.
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Intermittent hypoxia mobilizes bone marrow-derived very small embryonic-like stem cells and activates developmental transcriptional programs in mice. Sleep. 2010 Nov; 33(11):1439-46.