"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
|
| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 4 | 9 |
| 1996 | 6 | 1 | 7 |
| 1997 | 3 | 0 | 3 |
| 1998 | 9 | 5 | 14 |
| 1999 | 11 | 8 | 19 |
| 2000 | 5 | 6 | 11 |
| 2001 | 8 | 11 | 19 |
| 2002 | 8 | 13 | 21 |
| 2003 | 7 | 12 | 19 |
| 2004 | 7 | 27 | 34 |
| 2005 | 11 | 16 | 27 |
| 2006 | 11 | 20 | 31 |
| 2007 | 12 | 23 | 35 |
| 2008 | 14 | 20 | 34 |
| 2009 | 15 | 27 | 42 |
| 2010 | 6 | 19 | 25 |
| 2011 | 16 | 32 | 48 |
| 2012 | 11 | 19 | 30 |
| 2013 | 14 | 27 | 41 |
| 2014 | 11 | 33 | 44 |
| 2015 | 13 | 28 | 41 |
| 2016 | 8 | 50 | 58 |
| 2017 | 9 | 40 | 49 |
| 2018 | 14 | 27 | 41 |
| 2019 | 9 | 29 | 38 |
| 2020 | 14 | 28 | 42 |
| 2021 | 7 | 36 | 43 |
| 2022 | 3 | 42 | 45 |
| 2023 | 4 | 35 | 39 |
| 2024 | 5 | 14 | 19 |
| 2025 | 7 | 11 | 18 |
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Below are the most recent publications written about "Cytokines" by people in Profiles.
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eNAMPT Is a Novel DAMP and Therapeutic Target in Human and Murine Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2025 Oct; 73(4):572-585.
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Type I interferon limits central nervous system autoimmunity by modulating the microRNA-21-FOXO1 axis in pathogenic T helper 17 cells. Sci Transl Med. 2025 Sep 10; 17(815):eadp5802.
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Exogenous arginine differentially regulates inflammatory cytokine and inducible nitric oxide synthase expression in macrophages. Immunohorizons. 2025 07 14; 9(8).
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Macrophage phagocytosis of human norovirus-infected cells in an ex vivo human enteroid-macrophage coculture model. mBio. 2025 Aug 13; 16(8):e0118025.
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Efficacy of NAMPT inhibition in T-cell acute lymphoblastic leukemia. PLoS One. 2025; 20(6):e0324443.
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Shear Stress Conditioning Promotes a Pro-Inflammatory Response in Porcine Endocardial Endothelial Cells. Ann Biomed Eng. 2025 Sep; 53(9):2164-2177.
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Lack of an atypical PDR transporter generates an immunogenic Cryptococcus neoformans strain that drives a dysregulated and lethal immune response in murine lungs. mBio. 2025 Jul 09; 16(7):e0132125.
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Temporal Regulation of Early-Stage Cytokine Expression in Diabetic Wound Healing Under Negative Pressure Wound Therapy. Int J Mol Sci. 2025 May 13; 26(10).
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Identification of Distinct Biological Groups of Patients With Cryptogenic NORSE via Inflammatory Profiling. Neurol Neuroimmunol Neuroinflamm. 2025 Jul; 12(4):e200403.
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Impact of High-Titer Convalescent Plasma on Clinical and Virologic Outcomes Among Veterans Hospitalized With SARS-CoV-2 Infection: VA CoronavirUs Research and Efficacy Studies-1 (VA CURES-1). J Med Virol. 2025 May; 97(5):e70349.