"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
|
| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 6 | 1 | 7 |
| 1997 | 3 | 0 | 3 |
| 1998 | 8 | 2 | 10 |
| 1999 | 8 | 7 | 15 |
| 2000 | 4 | 6 | 10 |
| 2001 | 7 | 11 | 18 |
| 2002 | 7 | 14 | 21 |
| 2003 | 7 | 11 | 18 |
| 2004 | 7 | 24 | 31 |
| 2005 | 10 | 15 | 25 |
| 2006 | 11 | 20 | 31 |
| 2007 | 12 | 21 | 33 |
| 2008 | 13 | 19 | 32 |
| 2009 | 14 | 27 | 41 |
| 2010 | 6 | 19 | 25 |
| 2011 | 17 | 25 | 42 |
| 2012 | 9 | 18 | 27 |
| 2013 | 13 | 22 | 35 |
| 2014 | 10 | 30 | 40 |
| 2015 | 13 | 26 | 39 |
| 2016 | 6 | 49 | 55 |
| 2017 | 8 | 38 | 46 |
| 2018 | 16 | 24 | 40 |
| 2019 | 9 | 28 | 37 |
| 2020 | 13 | 23 | 36 |
| 2021 | 6 | 30 | 36 |
| 2022 | 2 | 37 | 39 |
| 2023 | 3 | 30 | 33 |
| 2024 | 3 | 15 | 18 |
| 2025 | 11 | 16 | 27 |
| 2026 | 7 | 16 | 23 |
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Below are the most recent publications written about "Cytokines" by people in Profiles.
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Urogenital immune signatures are associated with birth outcomes after maternal urinary tract infection. Sci Transl Med. 2026 Aug 26; 18(864):eaea1228.
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A cross-sectional analysis of the vaginal microenvironment in rheumatoid arthritis. Microbiol Spectr. 2026 Jun 02; 14(6):e0360225.
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Oncolytic viruses and cytokine-based gene therapies reprogram the tumor microenvironment. Nat Cancer. 2026 May; 7(5):723-739.
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Development and Internal Validation of a Pretransplant Biomarker Panel for Mortality Prediction Following Liver Transplant. JAMA Surg. 2026 Apr 01; 161(4):339-350.
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Therapeutic potential of hookworm proteins in promoting regulatory immune responses to modulate Trypanosoma cruzi induced liver inflammation and oxidative stress. Mem Inst Oswaldo Cruz. 2026; 121:e250123.
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Baseline Clinical Features and Biomarker Profiles of the Childhood Arthritis and Rheumatology Research Alliance Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease Cohort. Arthritis Care Res (Hoboken). 2026 Aug; 78(8):1036-1048.
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Immunotherapy of TSA-1.C4 or in combination with BNZ confers protection against Trypanosoma cruzi infection with a distinct cytokine response. Vaccine. 2026 Mar 19; 76:128296.
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Tumor-specific immune responses and biomarkers in pediatric patients with high-risk Hodgkin lymphoma. Blood Adv. 2026 Jan 13; 10(1):183-191.
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Impact of Anthelmintic Therapy for Invasive Helminth Infection on Microbial Translocation, Inflammation, and Immune Response among Ugandans Living with HIV: A Randomized Proof of Concept Study. Am J Trop Med Hyg. 2025 Dec 03; 113(6):1300-1310.
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Exogenous arginine differentially regulates inflammatory cytokine and inducible nitric oxide synthase expression in macrophages. Immunohorizons. 2025 07 14; 9(8).