"B7 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of cell-surface proteins found on ANTIGEN-PRESENTING CELLS. B7 antigens are ligands for specific cell surface receptor subtypes found on T-CELLS. They play an immunomodulatory role by stimulating or inhibiting the T-CELL activation process.
| Descriptor ID |
D060887
|
| MeSH Number(s) |
D12.776.467.150 D12.776.543.095 D23.050.301.285 D23.529.168
|
| Concept/Terms |
B7 Antigens- B7 Antigens
- Antigens, B7
- Antigen, B7
- B-7 Antigen
- Antigen, B-7
- B 7 Antigen
- B7 Costimulatory Molecules
- Costimulatory Molecules, B7
- B7 Molecules
- Molecules, B7
- B7 Antigen
|
Below are MeSH descriptors whose meaning is more general than "B7 Antigens".
Below are MeSH descriptors whose meaning is more specific than "B7 Antigens".
This graph shows the total number of publications written about "B7 Antigens" by people in this website by year, and whether "B7 Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "B7 Antigens" by people in Profiles.
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B7-H3 CAR T Cells Are Effective against Ependymomas but Limited by Tumor Size and Immune Response. Clin Cancer Res. 2025 Sep 02; 31(17):3754-3770.
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A Phase I, Open-Label, Dose Escalation Study of Enoblituzumab in Children and Young Adults with B7-H3-Expressing Relapsed or Refractory Solid Tumors. Cancer Res Commun. 2025 Sep 01; 5(9):1574-1583.
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VSIG-3/IGSF11 silencing in A2058 melanoma cells simultaneously suppresses melanoma progression and induces anti-tumoral cytokine profile in human T cells: In silico and in vitro study. Naunyn Schmiedebergs Arch Pharmacol. 2025 Apr; 398(4):3861-3880.
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Tumor B7-H3 expression in diagnostic biopsy specimens and survival in patients with metastatic prostate cancer. Prostate Cancer Prostatic Dis. 2021 09; 24(3):767-774.
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B7-H3 targeted antibody-based immunotherapy of malignant diseases. Expert Opin Biol Ther. 2021 05; 21(5):587-602.
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VISTA is a checkpoint regulator for na?ve T cell quiescence and peripheral tolerance. Science. 2020 01 17; 367(6475).
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High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma. Genome Res. 2019 08; 29(8):1211-1222.
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Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment. Cancer Immunol Res. 2019 07; 7(7):1079-1090.
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Genetic Polymorphism in Cytokines and Costimulatory Molecules in Stem Cell and Solid Organ Transplantation. Clin Lab Med. 2019 03; 39(1):107-123.
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VISTA expression on tumor-infiltrating inflammatory cells in primary cutaneous melanoma correlates with poor disease-specific survival. Cancer Immunol Immunother. 2018 Jul; 67(7):1113-1121.