"Chemokine CX3CL1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CX3C chemokine that is a transmembrane protein found on the surface of cells. The soluble form of chemokine CX3CL1 can be released from cell surface by proteolysis and act as a chemoattractant that may be involved in the extravasation of leukocytes into inflamed tissues. The membrane form of the protein may also play a role in cell adhesion.
| Descriptor ID |
D054428
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| MeSH Number(s) |
D12.644.276.374.200.130.500 D12.776.467.374.200.130.500 D12.776.543.193 D23.125.300.130.500 D23.469.200.130.500 D23.529.374.200.130.500
|
| Concept/Terms |
Chemokine CX3CL1- Chemokine CX3CL1
- CX3CL1, Chemokine
- CX3CL1 Chemokine
- Chemokine, CX3CL1
- Neurotactin
- Chemokine (C-X3-C Motif) Ligand 1
- Fractalkine
|
Below are MeSH descriptors whose meaning is more general than "Chemokine CX3CL1".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CX3CL1".
This graph shows the total number of publications written about "Chemokine CX3CL1" by people in this website by year, and whether "Chemokine CX3CL1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chemokine CX3CL1" by people in Profiles.
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The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy. Front Immunol. 2023; 14:1237715.
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Fractalkine suppression during hepatic encephalopathy promotes neuroinflammation in mice. J Neuroinflammation. 2016 08 26; 13(1):198.
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The CX3CL1/CX3CR1 reprograms glucose metabolism through HIF-1 pathway in pancreatic adenocarcinoma. J Cell Biochem. 2013 Nov; 114(11):2603-11.
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Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression. Ann Neurol. 2011 Mar; 69(3):570-80.
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Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide. J Neuroinflammation. 2010 Dec 17; 7:93.
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Microglial/macrophage GRK2 determines duration of peripheral IL-1beta-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling. Pain. 2010 Sep; 150(3):550-560.
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Fractalkine expression in the rhesus monkey brain during lentivirus infection and its control by 6-chloro-2',3'-dideoxyguanosine. J Neuropathol Exp Neurol. 2006 Dec; 65(12):1170-80.
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Nephritogenic anti-DNA antibodies regulate gene expression in MRL/lpr mouse glomerular mesangial cells. Arthritis Rheum. 2006 Jul; 54(7):2198-210.
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Cloning and characterization of a new type of mouse chemokine. Genomics. 1998 Jan 15; 47(2):163-70.