"Liver Failure, Acute" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Descriptor ID |
D017114
|
| MeSH Number(s) |
C06.552.308.500.750
|
| Concept/Terms |
Liver Failure, Acute- Liver Failure, Acute
- Failure, Acute Liver
- Fulminating Hepatic Failure
- Fulminating Hepatic Failures
- Hepatic Failure, Fulminating
- Hepatic Failures, Fulminating
- Liver Failure, Fulminant
- Fulminant Liver Failure
- Fulminant Liver Failures
- Liver Failures, Fulminant
- Hepatic Failure, Acute
- Acute Hepatic Failure
- Failure, Acute Hepatic
- Hepatic Failure, Fulminant
- Fulminant Hepatic Failure
- Fulminant Hepatic Failures
- Hepatic Failures, Fulminant
- Acute Liver Failure
- Fulminating Liver Failure
- Fulminating Liver Failures
- Liver Failure, Fulminating
- Liver Failures, Fulminating
|
Below are MeSH descriptors whose meaning is more general than "Liver Failure, Acute".
Below are MeSH descriptors whose meaning is more specific than "Liver Failure, Acute".
This graph shows the total number of publications written about "Liver Failure, Acute" by people in this website by year, and whether "Liver Failure, Acute" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
| 2005 | 3 | 0 | 3 |
| 2006 | 2 | 2 | 4 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 1 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 3 | 0 | 3 |
| 2013 | 2 | 0 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 3 | 0 | 3 |
| 2019 | 4 | 1 | 5 |
| 2020 | 2 | 1 | 3 |
| 2021 | 3 | 0 | 3 |
| 2022 | 3 | 0 | 3 |
| 2023 | 5 | 0 | 5 |
| 2024 | 3 | 2 | 5 |
| 2025 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Liver Failure, Acute" by people in Profiles.
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Acute liver failure and unique challenges of pediatric liver transplantation amidst a worldwide cluster of adenovirus-associated hepatitis. Am J Transplant. 2023 01; 23(1):93-100.
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Philadelphia chromosome-positive pre-B lymphoblastic leukemia presenting as acute hepatic failure in a pediatric patient. Pediatr Hematol Oncol. 2022 08; 39(5):481-487.
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Inhibition of thrombospondin-1 reduces glutathione activity and worsens acute liver injury during acetaminophen hepatotoxicity in mice. Toxicol Appl Pharmacol. 2020 12 15; 409:115323.
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Thrombospondin-1 Exacerbates Acute Liver Failure and Hepatic Encephalopathy Pathology in Mice by Activating Transforming Growth Factor ?1. Am J Pathol. 2020 02; 190(2):347-357.
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The TGF?1 Receptor Antagonist GW788388 Reduces JNK Activation and Protects Against Acetaminophen Hepatotoxicity in Mice. Toxicol Sci. 2019 05 01; 170(2):549-561.
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Elevated circulating TGF?1 during acute liver failure activates TGF?R2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice. J Neuroinflammation. 2019 Apr 02; 16(1):69.
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Regional citrate anticoagulation for continuous renal replacement therapy in pediatric patients with liver failure. PLoS One. 2017; 12(8):e0182134.
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Deliberate liver transplantation for fulminant liver failure with acute lymphoblastic leukemia. Liver Transpl. 2016 12; 22(12):1724-1726.
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Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure. Am J Pathol. 2016 Feb; 186(2):312-23.
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Prevalence, Severity, and Impact of Renal Dysfunction in Acute Liver Failure on the US Liver Transplant Waiting List. Dig Dis Sci. 2016 Jan; 61(1):309-16.