Transforming Growth Factor beta1
"Transforming Growth Factor beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
| Descriptor ID |
D053773
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| MeSH Number(s) |
D12.644.276.374.687.100 D12.644.276.954.775.100 D12.776.467.374.687.100 D12.776.467.942.775.100 D23.529.374.687.100 D23.529.942.775.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta1".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta1".
This graph shows the total number of publications written about "Transforming Growth Factor beta1" by people in this website by year, and whether "Transforming Growth Factor beta1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 7 | 7 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 4 | 5 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 4 | 2 | 6 |
| 2010 | 5 | 1 | 6 |
| 2011 | 0 | 3 | 3 |
| 2012 | 1 | 2 | 3 |
| 2013 | 4 | 7 | 11 |
| 2014 | 4 | 6 | 10 |
| 2015 | 5 | 3 | 8 |
| 2016 | 0 | 4 | 4 |
| 2017 | 0 | 3 | 3 |
| 2018 | 5 | 1 | 6 |
| 2019 | 3 | 1 | 4 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 1 | 2 |
| 2025 | 3 | 2 | 5 |
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click here.
Below are the most recent publications written about "Transforming Growth Factor beta1" by people in Profiles.
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Deletion of Megalin in Kidney Tubular Epithelium Up-Regulates TGF?1 Signaling, Aggravates Ischemia/Reperfusion Kidney Injury, and Accelerates the Progression to Chronic Kidney Disease. Am J Pathol. 2026 Mar; 196(3):657-668.
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Ataxia-telangiectasia mutated activation mediates transforming growth factor beta signaling in acetaminophen-induced liver injury in mice. Physiol Rep. 2025 Dec; 13(23):e70695.
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Exploring the Therapeutic Potential of Salivary Exosomes in Corneal Epithelial Wound Healing. Invest Ophthalmol Vis Sci. 2025 Aug 01; 66(11):8.
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Calcium-Sensing Receptor as a Novel Target for the Treatment of Idiopathic Pulmonary Fibrosis. Biomolecules. 2025 Apr 01; 15(4).
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Osteoprotegerin is induced by transforming growth factor-beta 1 and regulates pro-fibrotic responses in human dermal fibroblasts. Biochem Biophys Res Commun. 2025 03 25; 754:151524.
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Leukemia inhibitory factor (LIF) receptor amplifies pathogenic activation of fibroblasts in lung fibrosis. Proc Natl Acad Sci U S A. 2024 Dec 10; 121(50):e2401899121.
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PIK-III exerts anti-fibrotic effects in activated fibroblasts by regulating p38 activation. PLoS One. 2024; 19(9):e0306624.
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Tuftelin1 drives experimental pulmonary fibrosis progression by facilitating stress fiber assembly. Respir Res. 2023 Dec 17; 24(1):318.
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Novel Correlation between TGF-?1/-?3 and Hormone Receptors in the Human Corneal Stroma. Int J Mol Sci. 2023 Sep 04; 24(17).
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Contracting scars from fibrin drops. Integr Biol (Camb). 2022 03 21; 14(1):1-12.