Transforming Growth Factor beta1
"Transforming Growth Factor beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
| Descriptor ID |
D053773
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| MeSH Number(s) |
D12.644.276.374.687.100 D12.644.276.954.775.100 D12.776.467.374.687.100 D12.776.467.942.775.100 D23.529.374.687.100 D23.529.942.775.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta1".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta1".
This graph shows the total number of publications written about "Transforming Growth Factor beta1" by people in this website by year, and whether "Transforming Growth Factor beta1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 6 | 6 |
| 2002 | 0 | 11 | 11 |
| 2003 | 0 | 9 | 9 |
| 2004 | 0 | 17 | 17 |
| 2005 | 0 | 11 | 11 |
| 2006 | 1 | 6 | 7 |
| 2007 | 2 | 6 | 8 |
| 2008 | 4 | 3 | 7 |
| 2009 | 10 | 5 | 15 |
| 2010 | 6 | 3 | 9 |
| 2011 | 1 | 3 | 4 |
| 2012 | 3 | 3 | 6 |
| 2013 | 3 | 11 | 14 |
| 2014 | 6 | 10 | 16 |
| 2015 | 4 | 5 | 9 |
| 2016 | 1 | 4 | 5 |
| 2017 | 6 | 2 | 8 |
| 2018 | 8 | 1 | 9 |
| 2019 | 3 | 3 | 6 |
| 2020 | 4 | 2 | 6 |
| 2021 | 1 | 4 | 5 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 1 | 2 |
| 2024 | 0 | 3 | 3 |
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Below are the most recent publications written about "Transforming Growth Factor beta1" by people in Profiles.
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PIK-III exerts anti-fibrotic effects in activated fibroblasts by regulating p38 activation. PLoS One. 2024; 19(9):e0306624.
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Role of hypoxia-mediated pyroptosis?in the development of extending knee joint contracture in rats. Eur J Med Res. 2024 May 27; 29(1):298.
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TGF-?1 and TGF-?R1 variants are associated with clinical outcomes in smoking-related head and neck cancer patients treated with chemoradiation through modulating microRNA-mediated regulation. Cancer Immunol Immunother. 2024 Mar 30; 73(5):85.
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Tuftelin1 drives experimental pulmonary fibrosis progression by facilitating stress fiber assembly. Respir Res. 2023 Dec 17; 24(1):318.
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SKIL/SnoN attenuates TGF-?1/SMAD signaling-dependent collagen synthesis in hepatic fibrosis. Biomol Biomed. 2023 Nov 03; 23(6):1014-1025.
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Growth hormone induces transforming growth factor-?1 in podocytes: Implications in podocytopathy and proteinuria. Biochim Biophys Acta Mol Cell Res. 2023 02; 1870(2):119391.
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Endothelial cell cycle state determines propensity for arterial-venous fate. Nat Commun. 2022 10 06; 13(1):5891.
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Haploinsufficiency of Tmem43 in cardiac myocytes activates the DNA damage response pathway leading to a late-onset senescence-associated pro-fibrotic cardiomyopathy. Cardiovasc Res. 2021 09 28; 117(11):2377-2394.
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Optimization strategies for expression of a novel bifunctional anti-PD-L1/TGFBR2-ECD fusion protein. Protein Expr Purif. 2022 01; 189:105973.
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Alpha-single chains of collagen type VI inhibit the fibrogenic effects of triple helical collagen VI in hepatic stellate cells. PLoS One. 2021; 16(9):e0254557.