Transforming Growth Factor beta
"Transforming Growth Factor beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
| Descriptor ID |
D016212
|
| MeSH Number(s) |
D12.644.276.374.687 D12.644.276.954.775 D12.776.467.374.687 D12.776.467.942.775 D23.529.374.687 D23.529.942.775
|
| Concept/Terms |
Transforming Growth Factor beta- Transforming Growth Factor beta
- Milk Growth Factor
- Factor, Milk Growth
- Growth Factor, Milk
- TGF-beta
- TGFbeta
- Platelet Transforming Growth Factor
- Bone-Derived Transforming Growth Factor
- Bone Derived Transforming Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta".
This graph shows the total number of publications written about "Transforming Growth Factor beta" by people in this website by year, and whether "Transforming Growth Factor beta" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 10 | 5 | 15 |
| 1995 | 9 | 4 | 13 |
| 1996 | 11 | 4 | 15 |
| 1997 | 13 | 3 | 16 |
| 1998 | 12 | 20 | 32 |
| 1999 | 20 | 10 | 30 |
| 2000 | 12 | 10 | 22 |
| 2001 | 19 | 7 | 26 |
| 2002 | 16 | 23 | 39 |
| 2003 | 18 | 9 | 27 |
| 2004 | 22 | 14 | 36 |
| 2005 | 17 | 15 | 32 |
| 2006 | 20 | 10 | 30 |
| 2007 | 14 | 12 | 26 |
| 2008 | 11 | 14 | 25 |
| 2009 | 5 | 9 | 14 |
| 2010 | 11 | 14 | 25 |
| 2011 | 13 | 16 | 29 |
| 2012 | 12 | 15 | 27 |
| 2013 | 15 | 14 | 29 |
| 2014 | 5 | 10 | 15 |
| 2015 | 10 | 9 | 19 |
| 2016 | 10 | 6 | 16 |
| 2017 | 11 | 9 | 20 |
| 2018 | 8 | 10 | 18 |
| 2019 | 9 | 16 | 25 |
| 2020 | 5 | 8 | 13 |
| 2021 | 4 | 3 | 7 |
| 2022 | 2 | 13 | 15 |
| 2023 | 4 | 3 | 7 |
| 2024 | 3 | 6 | 9 |
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Below are the most recent publications written about "Transforming Growth Factor beta" by people in Profiles.
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TGF-? trap of AdAPT-001 turns up the heat on tumors and turns down checkpoint blocker resistance. J Immunother Cancer. 2024 Oct 26; 12(10).
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Mitral Annular Disjunction in Heritable Thoracic Aortic Disease: Insights From the Montalcino Aortic Consortium. J Am Heart Assoc. 2024 Nov 05; 13(21):e036274.
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Dual optical elastography detects TGF-? -induced alterations in the biomechanical properties of skin scaffolds. J Biomed Opt. 2024 Sep; 29(9):095002.
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BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML. Sci Transl Med. 2024 Sep 11; 16(764):eadp0004.
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Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence. Cancer Cell. 2024 Sep 09; 42(9):1507-1527.e11.
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Fibroblast Smad7 Induction Protects the Remodeling Pressure-Overloaded Heart. Circ Res. 2024 Jul 19; 135(3):453-469.
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BIGH3 mediates apoptosis and gap junction failure in osteocytes during renal cell carcinoma bone metastasis progression. Cancer Lett. 2024 Aug 01; 596:217009.
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Thbs1 regulates skeletal muscle mass in a TGF?-Smad2/3-ATF4-dependent manner. Cell Rep. 2024 May 28; 43(5):114149.
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Endothelial-to-Mesenchymal Transition in Human and Murine Models of Congenital Diaphragmatic Hernia. Neonatology. 2024; 121(4):512-518.
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Impaired bone morphogenetic protein (BMP) signaling pathways disrupt decidualization in endometriosis. Commun Biol. 2024 Feb 24; 7(1):227.