Transforming Growth Factor beta
"Transforming Growth Factor beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
Descriptor ID |
D016212
|
MeSH Number(s) |
D12.644.276.374.687 D12.644.276.954.775 D12.776.467.374.687 D12.776.467.942.775 D23.529.374.687 D23.529.942.775
|
Concept/Terms |
Transforming Growth Factor beta- Transforming Growth Factor beta
- Milk Growth Factor
- Factor, Milk Growth
- Growth Factor, Milk
- TGF-beta
- TGFbeta
- Platelet Transforming Growth Factor
- Bone-Derived Transforming Growth Factor
- Bone Derived Transforming Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta".
This graph shows the total number of publications written about "Transforming Growth Factor beta" by people in this website by year, and whether "Transforming Growth Factor beta" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1994 | 10 | 5 | 15 |
1995 | 8 | 5 | 13 |
1996 | 11 | 4 | 15 |
1997 | 12 | 4 | 16 |
1998 | 12 | 20 | 32 |
1999 | 18 | 9 | 27 |
2000 | 11 | 9 | 20 |
2001 | 15 | 5 | 20 |
2002 | 10 | 13 | 23 |
2003 | 19 | 8 | 27 |
2004 | 21 | 14 | 35 |
2005 | 16 | 16 | 32 |
2006 | 22 | 11 | 33 |
2007 | 14 | 12 | 26 |
2008 | 11 | 14 | 25 |
2009 | 5 | 9 | 14 |
2010 | 12 | 16 | 28 |
2011 | 13 | 16 | 29 |
2012 | 12 | 15 | 27 |
2013 | 16 | 14 | 30 |
2014 | 5 | 11 | 16 |
2015 | 10 | 12 | 22 |
2016 | 11 | 6 | 17 |
2017 | 10 | 10 | 20 |
2018 | 8 | 8 | 16 |
2019 | 9 | 16 | 25 |
2020 | 7 | 8 | 15 |
2021 | 5 | 2 | 7 |
2022 | 4 | 18 | 22 |
2023 | 4 | 4 | 8 |
2024 | 0 | 2 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Transforming Growth Factor beta" by people in Profiles.
-
Impaired bone morphogenetic protein (BMP) signaling pathways disrupt decidualization in endometriosis. Commun Biol. 2024 Feb 24; 7(1):227.
-
TGF-? as a therapeutic target in the infarcted and failing heart: cellular mechanisms, challenges, and opportunities. Expert Opin Ther Targets. 2024 Jan-Feb; 28(1-2):45-56.
-
Nonsense Variant PRDM16-Q187X Causes Impaired Myocardial Development and TGF-? Signaling Resulting in Noncompaction Cardiomyopathy in Humans and Mice. Circ Heart Fail. 2023 Dec; 16(12):e010351.
-
Unlocking the miRNA-34a-5p/TGF-? and HMGB1/PI3K/Akt/mTOR crosstalk participate in the enhanced cardiac protection of liraglutide against isoproterenol-induced acute myocardial injury rat model. Int Immunopharmacol. 2024 Jan 25; 127:111369.
-
Endometrial TGF? signaling fosters early pregnancy development by remodeling the fetomaternal interface. Am J Reprod Immunol. 2023 12; 90(6):e13789.
-
TGF? signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells. Cell Mol Life Sci. 2023 Sep 09; 80(10):288.
-
Comparison of Four Protocols for In Vitro Differentiation of Human Embryonic Stem Cells into Trophoblast Lineages by BMP4 and Dual Inhibition of Activin/Nodal and FGF2 Signaling. Reprod Sci. 2024 Jan; 31(1):173-189.
-
Functional Genetic Variants in TGF?1 and TGF?R1 in miRNA-Binding Sites Predict Outcomes in Patients with HPV-positive Oropharyngeal Squamous Cell Carcinoma. Clin Cancer Res. 2023 08 15; 29(16):3081-3091.
-
Proactive and reactive roles of TGF-? in cancer. Semin Cancer Biol. 2023 10; 95:120-139.
-
Cardiac Pericytes Acquire a Fibrogenic Phenotype and Contribute to Vascular Maturation After Myocardial Infarction. Circulation. 2023 09 12; 148(11):882-898.