Growth Differentiation Factor 15
"Growth Differentiation Factor 15" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.
| Descriptor ID |
D055436
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| MeSH Number(s) |
D12.644.276.374.305 D12.644.276.954.300.915 D12.776.467.374.305 D12.776.467.942.300.915 D23.529.374.305 D23.529.942.300.915
|
| Concept/Terms |
Growth Differentiation Factor 15- Growth Differentiation Factor 15
- Macrophage Inhibitory Cytokine 1
- Prostate Differentiation Factor
- Differentiation Factor, Prostate
- GDF-15
|
Below are MeSH descriptors whose meaning is more general than "Growth Differentiation Factor 15".
Below are MeSH descriptors whose meaning is more specific than "Growth Differentiation Factor 15".
This graph shows the total number of publications written about "Growth Differentiation Factor 15" by people in this website by year, and whether "Growth Differentiation Factor 15" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 3 | 0 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 2 | 2 | 4 |
| 2023 | 0 | 2 | 2 |
| 2024 | 2 | 1 | 3 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Growth Differentiation Factor 15" by people in Profiles.
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Health implications of racial differences in serum growth differentiation factor levels among men with obesity. Physiol Rep. 2024 12; 12(23):e70124.
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Loss of growth differentiation factor 15 exacerbates lung injury in neonatal mice. Am J Physiol Lung Cell Mol Physiol. 2023 09 01; 325(3):L314-L326.
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Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates. Pediatr Pulmonol. 2023 01; 58(1):271-278.
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Growth Differentiation Factor 15 and the Subsequent Risk of Atrial Fibrillation: The Atherosclerosis Risk in Communities Study. Clin Chem. 2022 07 27; 68(8):1084-1093.
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Heightened levels of plasma growth differentiation factor 15 in men living with HIV. Physiol Rep. 2022 05; 10(9):e15293.
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Growth differentiation factor 15 protects against the aging-mediated systemic inflammatory response in humans and mice. Aging Cell. 2020 08; 19(8):e13195.
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Relations of circulating GDF-15, soluble ST2, and troponin-I concentrations with vascular function in the community: The Framingham Heart Study. Atherosclerosis. 2016 May; 248:245-51.
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Acute exacerbations of chronic obstructive pulmonary disease are associated with decreased CD4+ & CD8+ T cells and increased growth & differentiation factor-15 (GDF-15) in peripheral blood. Respir Res. 2015 Aug 05; 16:94.
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Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis. J Exp Med. 2011 Feb 14; 208(2):217-25.
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Diagnostic markers for early detection of ovarian cancer. Clin Cancer Res. 2008 Feb 15; 14(4):1065-72.