Growth Differentiation Factor 15
"Growth Differentiation Factor 15" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.
| Descriptor ID |
D055436
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| MeSH Number(s) |
D12.644.276.374.305 D12.644.276.954.300.915 D12.776.467.374.305 D12.776.467.942.300.915 D23.529.374.305 D23.529.942.300.915
|
| Concept/Terms |
Growth Differentiation Factor 15- Growth Differentiation Factor 15
- Macrophage Inhibitory Cytokine 1
- Prostate Differentiation Factor
- Differentiation Factor, Prostate
- GDF-15
|
Below are MeSH descriptors whose meaning is more general than "Growth Differentiation Factor 15".
Below are MeSH descriptors whose meaning is more specific than "Growth Differentiation Factor 15".
This graph shows the total number of publications written about "Growth Differentiation Factor 15" by people in this website by year, and whether "Growth Differentiation Factor 15" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 3 | 1 | 4 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 2 | 1 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Growth Differentiation Factor 15" by people in Profiles.
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Health implications of racial differences in serum growth differentiation factor levels among men with obesity. Physiol Rep. 2024 Dec; 12(23):e70124.
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Protein biomarkers GDF15 and FGF21 to differentiate mitochondrial hepatopathies from other pediatric liver diseases. Hepatol Commun. 2024 01 01; 8(1).
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Loss of growth differentiation factor 15 exacerbates lung injury in neonatal mice. Am J Physiol Lung Cell Mol Physiol. 2023 09 01; 325(3):L314-L326.
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The GDF15-GFRAL axis mediates chemotherapy-induced fatigue in mice. Brain Behav Immun. 2023 Feb; 108:45-54.
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Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates. Pediatr Pulmonol. 2023 01; 58(1):271-278.
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Heightened levels of plasma growth differentiation factor 15 in men living with HIV. Physiol Rep. 2022 05; 10(9):e15293.
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Apomorphine rescues reactive oxygen species-induced apoptosis of fibroblasts with mitochondrial disease. Mitochondrion. 2019 11; 49:111-120.
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Sex-specific differences in the modulation of Growth Differentiation Factor 15 (GDF15) by hyperoxia in vivo and in vitro: Role of Hif-1a. Toxicol Appl Pharmacol. 2017 10 01; 332:8-14.
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GDF-15 plasma levels in chronic obstructive pulmonary disease are associated with subclinical coronary artery disease. Respir Res. 2017 02 28; 18(1):42.
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Relations of circulating GDF-15, soluble ST2, and troponin-I concentrations with vascular function in the community: The Framingham Heart Study. Atherosclerosis. 2016 May; 248:245-51.