Hydroxymethylglutaryl-CoA Reductase Inhibitors
"Hydroxymethylglutaryl-CoA Reductase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.
| Descriptor ID |
D019161
|
| MeSH Number(s) |
D27.505.519.186.071.202.370 D27.505.519.389.370 D27.505.954.557.500.202.370
|
| Concept/Terms |
Hydroxymethylglutaryl-CoA Reductase Inhibitors- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Hydroxymethylglutaryl CoA Reductase Inhibitors
- Inhibitors, Hydroxymethylglutaryl-CoA Reductase
- Reductase Inhibitors, Hydroxymethylglutaryl-CoA
- Inhibitors, HMG-CoA Reductase
- Inhibitors, HMG CoA Reductase
- Reductase Inhibitors, HMG-CoA
- HMG-CoA Reductase Inhibitors
- HMG CoA Reductase Inhibitors
- Statins, HMG-CoA
- HMG-CoA Statins
- Statins, HMG CoA
- Inhibitors, Hydroxymethylglutaryl-CoA
- Hydroxymethylglutaryl-CoA Inhibitors
- Inhibitors, Hydroxymethylglutaryl CoA
- Statins
- Inhibitors, Hydroxymethylglutaryl-Coenzyme A
- Hydroxymethylglutaryl-Coenzyme A Inhibitors
- Inhibitors, Hydroxymethylglutaryl Coenzyme A
|
Below are MeSH descriptors whose meaning is more general than "Hydroxymethylglutaryl-CoA Reductase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Hydroxymethylglutaryl-CoA Reductase Inhibitors".
This graph shows the total number of publications written about "Hydroxymethylglutaryl-CoA Reductase Inhibitors" by people in this website by year, and whether "Hydroxymethylglutaryl-CoA Reductase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 2 | 3 |
| 1997 | 0 | 1 | 1 |
| 1998 | 3 | 0 | 3 |
| 1999 | 3 | 0 | 3 |
| 2000 | 3 | 1 | 4 |
| 2001 | 6 | 0 | 6 |
| 2002 | 3 | 1 | 4 |
| 2003 | 5 | 6 | 11 |
| 2004 | 8 | 3 | 11 |
| 2005 | 10 | 1 | 11 |
| 2006 | 9 | 5 | 14 |
| 2007 | 16 | 4 | 20 |
| 2008 | 12 | 2 | 14 |
| 2009 | 9 | 0 | 9 |
| 2010 | 14 | 3 | 17 |
| 2011 | 12 | 9 | 21 |
| 2012 | 9 | 3 | 12 |
| 2013 | 19 | 3 | 22 |
| 2014 | 17 | 10 | 27 |
| 2015 | 19 | 7 | 26 |
| 2016 | 23 | 12 | 35 |
| 2017 | 16 | 6 | 22 |
| 2018 | 30 | 7 | 37 |
| 2019 | 31 | 15 | 46 |
| 2020 | 14 | 5 | 19 |
| 2021 | 28 | 6 | 34 |
| 2022 | 36 | 0 | 36 |
| 2023 | 22 | 0 | 22 |
| 2024 | 7 | 3 | 10 |
| 2025 | 7 | 4 | 11 |
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Below are the most recent publications written about "Hydroxymethylglutaryl-CoA Reductase Inhibitors" by people in Profiles.
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The evolving landscape of targets for lipid lowering: from molecular mechanisms to translational implications. Eur Heart J. 2025 Nov 21; 46(44):4737-4750.
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Clinical impact of pharmacogenetic risk variants in a large chinese cohort. Nat Commun. 2025 Jul 09; 16(1):6344.
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Treatment of severe hyperlipidemia and associated cardiovascular outcomes: Data from a large healthcare system. J Clin Lipidol. 2025 Sep-Oct; 19(5):1256-1263.
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Using a Markov Model and Real-World Evidence to Identify the Most Cost-Effective Cholesterol Treatment Escalation Threshold for the Secondary Prevention of Cardiovascular Disease. Appl Health Econ Health Policy. 2025 Sep; 23(5):869-883.
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Impact of Periprocedural Statin Therapy on Mortality and Cardiovascular Outcomes in Transcatheter Aortic Valve Replacement: A Meta-Analysis and Meta-Regression. Catheter Cardiovasc Interv. 2025 Jul; 106(1):720-729.
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Association of statin use on survival outcomes of patients with early-stage HER2-positive breast cancer in the APHINITY trial. Breast Cancer Res Treat. 2025 Jul; 212(1):57-69.
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Cholesterol Pathway Gene Variants and Reduced Keratinocyte Cholesterol Support a Final Common Druggable Pathway in Hyperproliferative Inflammatory Skin Diseases. J Invest Dermatol. 2025 Nov; 145(11):2745-2752.e7.
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Cardiac Troponins and Cardiovascular Disease Risk Prediction: An Individual-Participant-Data Meta-Analysis. J Am Coll Cardiol. 2025 Apr 15; 85(14):1471-1484.
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Managing hypercholesterolemia in adults older than 75 years without a history of atherosclerotic cardiovascular disease: An Expert Clinical Consensus from the National Lipid Association and the American Geriatrics Society. J Clin Lipidol. 2025 Mar-Apr; 19(2):215-237.
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Managing Hypercholesterolemia in Adults Older Than 75?years Without a History of Atherosclerotic Cardiovascular Disease: An Expert Clinical Consensus From the National Lipid Association and the American Geriatrics Society. J Am Geriatr Soc. 2025 Jun; 73(6):1674-1696.