"Lipoxygenase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that bind to and inhibit that enzymatic activity of LIPOXYGENASES. Included under this category are inhibitors that are specific for lipoxygenase subtypes and act to reduce the production of LEUKOTRIENES.
| Descriptor ID |
D016859
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| MeSH Number(s) |
D27.505.519.389.480
|
| Concept/Terms |
Arachidonate 15-Lipoxygenase Inhibitors- Arachidonate 15-Lipoxygenase Inhibitors
- 15-Lipoxygenase Inhibitors, Arachidonate
- Arachidonate 15 Lipoxygenase Inhibitors
- Inhibitors, Arachidonate 15-Lipoxygenase
- 15-Lipoxygenase Inhibitors
- 15 Lipoxygenase Inhibitors
- Inhibitors, 15-Lipoxygenase
Arachidonate 5-Lipoxygenase Inhibitors- Arachidonate 5-Lipoxygenase Inhibitors
- 5-Lipoxygenase Inhibitors, Arachidonate
- Arachidonate 5 Lipoxygenase Inhibitors
- Inhibitors, Arachidonate 5-Lipoxygenase
- 5-Lipoxygenase Inhibitors
- 5 Lipoxygenase Inhibitors
- Inhibitors, 5-Lipoxygenase
Arachidonate 12-Lipoxygenase Inhibitors- Arachidonate 12-Lipoxygenase Inhibitors
- 12-Lipoxygenase Inhibitors, Arachidonate
- Arachidonate 12 Lipoxygenase Inhibitors
- Inhibitors, Arachidonate 12-Lipoxygenase
- 12-Lipoxygenase Inhibitors
- 12 Lipoxygenase Inhibitors
- Inhibitors, 12-Lipoxygenase
|
Below are MeSH descriptors whose meaning is more general than "Lipoxygenase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Lipoxygenase Inhibitors".
This graph shows the total number of publications written about "Lipoxygenase Inhibitors" by people in this website by year, and whether "Lipoxygenase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 2 | 3 | 5 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 2 | 3 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Lipoxygenase Inhibitors" by people in Profiles.
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Effect of zileuton and celecoxib on urinary LTE4 and PGE-M levels in smokers. Cancer Prev Res (Phila). 2013 Jul; 6(7):646-55.
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Randomized trial of zileuton for treatment of COPD exacerbations requiring hospitalization. COPD. 2011 Feb; 8(1):21-9.
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Pharmacological nature of nicotine-induced contraction in the rat basilar artery: involvement of arachidonic acid metabolites. Eur J Pharmacol. 2007 Dec 22; 577(1-3):109-14.
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Zyflamend-mediated inhibition of human prostate cancer PC3 cell proliferation: effects on 12-LOX and Rb protein phosphorylation. Cancer Biol Ther. 2007 Feb; 6(2):228-36.
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Simultaneous inhibition of COX-2 and 5-LOX activities augments growth arrest and death of premalignant and malignant human lung cell lines. J Exp Ther Oncol. 2007; 6(3):183-92.
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15-Lipoxygenase-2 gene regulation by its product 15-(S)-hydroxyeicosatetraenoic acid through a negative feedback mechanism that involves peroxisome proliferator-activated receptor gamma. Oncogene. 2006 Sep 28; 25(44):6015-25.
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Cysteinyl leukotrienes and leukotriene B mediate vasoconstriction to arginine vasopressin in rat basilar artery. Clin Exp Pharmacol Physiol. 2005 Dec; 32(12):1027-33.
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Involvement of endothelial cyclo-oxygenase metabolites in noradrenaline-induced contraction of rat coronary artery. Clin Exp Pharmacol Physiol. 2005 Aug; 32(8):628-32.
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Alpha-tocopherol decreases tumor necrosis factor-alpha mRNA and protein from activated human monocytes by inhibition of 5-lipoxygenase. Free Radic Biol Med. 2005 May 01; 38(9):1212-20.
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Increased 5-lipoxygenase expression and induction of apoptosis by its inhibitors in esophageal cancer: a potential target for prevention. Carcinogenesis. 2005 Apr; 26(4):785-91.