Carbonic Anhydrase Inhibitors
"Carbonic Anhydrase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of compounds that reduces the secretion of H+ ions by the proximal kidney tubule through inhibition of CARBONIC ANHYDRASES.
| Descriptor ID |
D002257
|
| MeSH Number(s) |
D27.505.519.389.200
|
| Concept/Terms |
Carbonic Anhydrase Inhibitors- Carbonic Anhydrase Inhibitors
- Inhibitors, Carbonic Anhydrase
- Carbonate Dehydratase Inhibitors
- Inhibitors, Carbonate Dehydratase
- Carboxyanhydrase Inhibitors
- Inhibitors, Carboxyanhydrase
|
Below are MeSH descriptors whose meaning is more general than "Carbonic Anhydrase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Carbonic Anhydrase Inhibitors".
This graph shows the total number of publications written about "Carbonic Anhydrase Inhibitors" by people in this website by year, and whether "Carbonic Anhydrase Inhibitors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2016 | 4 | 0 | 4 |
| 2017 | 1 | 1 | 2 |
| 2018 | 3 | 1 | 4 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Carbonic Anhydrase Inhibitors" by people in Profiles.
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First-in-Class Dual Targeting Compounds for the Management of Seizures in Glucose Transporter Type 1 Deficiency Syndrome. J Med Chem. 2023 07 27; 66(14):10010-10026.
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McArdle Disease Rhabdomyolysis Precipitated by Acetazolamide for Idiopathic Intracranial Hypertension. J Neuroophthalmol. 2023 Dec 01; 43(4):e159-e160.
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Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004): in?vitro and in?vivo studies. J Enzyme Inhib Med Chem. 2021 Dec; 36(1):954-963.
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Discovery of Potent Carbonic Anhydrase Inhibitors as Effective Anticonvulsant Agents: Drug Design, Synthesis, and In Vitro and In Vivo Investigations. J Med Chem. 2021 03 25; 64(6):3100-3114.
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Computational discovery of plant-based inhibitors against human carbonic anhydrase IX and molecular dynamics simulation. J Biomol Struct Dyn. 2021 May; 39(8):2754-2770.
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Acetazolamide Mitigates Intracranial Pressure Spikes Without Affecting Functional Outcome After Experimental Hemorrhagic Stroke. Transl Stroke Res. 2019 08; 10(4):428-439.
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Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in?vitro and in?vivo appraisal. Eur J Med Chem. 2018 Aug 05; 156:430-443.
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Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation. J Med Chem. 2018 04 12; 61(7):3151-3165.
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Five-Year-Old Boy With Behavioral Changes and Papilledema. J Neuroophthalmol. 2018 03; 38(1):75-80.
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Comparison of Efficacy and Complications of Cyclophotocoagulation and Second Glaucoma Drainage Device After Initial Glaucoma Drainage Device Failure. J Glaucoma. 2017 Nov; 26(11):1010-1018.