Phosphodiesterase Inhibitors
"Phosphodiesterase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.
| Descriptor ID |
D010726
|
| MeSH Number(s) |
D27.505.519.389.735
|
| Concept/Terms |
Phosphodiesterase Inhibitors- Phosphodiesterase Inhibitors
- Phosphodiesterase Antagonists
- Phosphoric Diester Hydrolase Inhibitors
- Antiphosphodiesterases
|
Below are MeSH descriptors whose meaning is more general than "Phosphodiesterase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Phosphodiesterase Inhibitors".
This graph shows the total number of publications written about "Phosphodiesterase Inhibitors" by people in this website by year, and whether "Phosphodiesterase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 4 | 0 | 4 |
| 2000 | 2 | 1 | 3 |
| 2001 | 0 | 3 | 3 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 1 | 3 |
| 2005 | 2 | 2 | 4 |
| 2006 | 4 | 2 | 6 |
| 2007 | 0 | 3 | 3 |
| 2008 | 2 | 2 | 4 |
| 2009 | 2 | 4 | 6 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 2 | 3 |
| 2014 | 0 | 2 | 2 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphodiesterase Inhibitors" by people in Profiles.
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Development of PDE6D and CK1a Degraders through Chemical Derivatization of FPFT-2216. J Med Chem. 2022 01 13; 65(1):747-756.
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Management of asthma COPD overlap. Ann Allergy Asthma Immunol. 2019 10; 123(4):335-344.
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Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism. Proc Natl Acad Sci U S A. 2018 10 16; 115(42):10756-10761.
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Pentoxifylline for treatment of sepsis and necrotizing enterocolitis in neonates. Cochrane Database Syst Rev. 2015 Mar 09; (3):CD004205.
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Gcn5 and PCAF regulate PPAR? and Prdm16 expression to facilitate brown adipogenesis. Mol Cell Biol. 2014 Oct 01; 34(19):3746-53.
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Minimally invasive treatment of Peyronie's disease: evidence-based progress. BJU Int. 2014 Jul; 114(1):16-24.
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Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol. Am J Physiol Cell Physiol. 2013 Aug 01; 305(3):C276-89.
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EAU guidelines on the treatment and follow-up of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction. Eur Urol. 2013 Jul; 64(1):118-40.
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Sexual dysfunction among male veterans returning from Iraq and Afghanistan: prevalence and correlates. J Sex Med. 2013 Feb; 10(2):516-23.
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Novel treatments for NEC: keeping IBD in mind. Curr Gastroenterol Rep. 2012 Oct; 14(5):373-9.