"Proton Pump Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit H(+)-K(+)-EXCHANGING ATPASE. They are used as ANTI-ULCER AGENTS and sometimes in place of HISTAMINE H2 ANTAGONISTS for GASTROESOPHAGEAL REFLUX.
| Descriptor ID |
D054328
|
| MeSH Number(s) |
D27.505.519.389.848
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Proton Pump Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Proton Pump Inhibitors".
This graph shows the total number of publications written about "Proton Pump Inhibitors" by people in this website by year, and whether "Proton Pump Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 1 | 2 |
| 2003 | 2 | 1 | 3 |
| 2004 | 1 | 4 | 5 |
| 2005 | 3 | 0 | 3 |
| 2006 | 2 | 2 | 4 |
| 2007 | 4 | 1 | 5 |
| 2008 | 4 | 1 | 5 |
| 2009 | 3 | 5 | 8 |
| 2010 | 5 | 2 | 7 |
| 2011 | 6 | 3 | 9 |
| 2012 | 5 | 5 | 10 |
| 2013 | 3 | 6 | 9 |
| 2014 | 3 | 2 | 5 |
| 2015 | 14 | 5 | 19 |
| 2016 | 8 | 5 | 13 |
| 2017 | 6 | 5 | 11 |
| 2018 | 10 | 4 | 14 |
| 2019 | 7 | 4 | 11 |
| 2020 | 7 | 2 | 9 |
| 2021 | 3 | 1 | 4 |
| 2022 | 0 | 7 | 7 |
| 2023 | 1 | 6 | 7 |
| 2024 | 4 | 5 | 9 |
| 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Proton Pump Inhibitors" by people in Profiles.
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Proton pump inhibitors and the risk of gastric cancer: a systematic review, evidence synthesis and life course epidemiology perspective. BMJ Open Gastroenterol. 2025 Apr 19; 12(1).
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Pediatric Laryngopharyngeal Reflux: Epidemiology, Clinical Presentation, Diagnosis, and Therapeutic Outcomes. Otolaryngol Clin North Am. 2025 Jun; 58(3):507-517.
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Impact of an Electronic Medical Record Quality Improvement Intervention on Helicobacter pylori Treatment and Eradication Rates in a U.S. Hospital System. Helicobacter. 2025 Mar-Apr; 30(2):e70034.
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Proton pump inhibitor effect on macrophage and neutrophil function: a systematic review. Front Immunol. 2024; 15:1477993.
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Effects of amoxicillin dosage on cure rate, gut microbiota, and?antibiotic resistome in vonoprazan and amoxicillin dual therapy for Helicobacter pylori: a multicentre, open-label, non-inferiority randomised controlled trial. Lancet Microbe. 2025 Mar; 6(3):100975.
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American Society for Gastrointestinal Endoscopy guideline on the diagnosis and management of GERD: summary and recommendations. Gastrointest Endosc. 2025 Feb; 101(2):267-284.
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Efficacy of Bismuth Quadruple Therapy in the Treatment of Helicobacter pylori-Infected Peptic Ulcer Children in Vietnam. Helicobacter. 2024 Nov-Dec; 29(6):e13149.
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Gastrointestinal manifestations of Rett syndrome: An updated analysis using the Gastrointestinal Health Questionnaire. J Pediatr Gastroenterol Nutr. 2025 Jan; 80(1):46-56.
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Comparative Efficacy and Safety of Potassium-Competitive Acid Blocker-Based Dual, Triple, and Quadruple Regimens for First-Line Helicobacter pylori Infection Treatment: A Systematic Review and Network Meta-Analysis. Am J Gastroenterol. 2025 Apr 01; 120(4):787-798.
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Clinical implications of combination proton pump inhibitor and triple therapies in patients with atrial fibrillation following percutaneous intervention: a guide for clinicians. Expert Rev Cardiovasc Ther. 2024 Sep; 22(9):483-491.