Protein Synthesis Inhibitors
"Protein Synthesis Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
| Descriptor ID |
D011500
|
| MeSH Number(s) |
D27.505.519.389.760
|
| Concept/Terms |
Protein Synthesis Inhibitors- Protein Synthesis Inhibitors
- Inhibitors, Protein Synthesis
- Protein Synthesis Antagonists
- Antagonists, Protein Synthesis
|
Below are MeSH descriptors whose meaning is more general than "Protein Synthesis Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Protein Synthesis Inhibitors".
This graph shows the total number of publications written about "Protein Synthesis Inhibitors" by people in this website by year, and whether "Protein Synthesis Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2011 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Synthesis Inhibitors" by people in Profiles.
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Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors. Genes Dev. 2019 07 01; 33(13-14):871-885.
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Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress. Cell. 2015 Sep 10; 162(6):1286-98.
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Actin polymerization is essential for myelin sheath fragmentation during Wallerian degeneration. J Neurosci. 2011 Feb 09; 31(6):2009-15.
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Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation. Proc Natl Acad Sci U S A. 2011 Feb 22; 108(8):3383-8.
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Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones. Traffic. 2009 Aug; 10(8):1019-33.
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Coatomer-dependent protein delivery to lipid droplets. J Cell Sci. 2009 Jun 01; 122(Pt 11):1834-41.
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Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models. J Neurophysiol. 2009 May; 101(5):2572-80.
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TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells. Mol Cancer Res. 2008 May; 6(5):862-72.
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Drosophila alpha/beta mushroom body neurons form a branch-specific, long-term cellular memory trace after spaced olfactory conditioning. Neuron. 2006 Dec 07; 52(5):845-55.
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RNA therapeutics directed to the non coding regions of APP mRNA, in vivo anti-amyloid efficacy of paroxetine, erythromycin, and N-acetyl cysteine. Curr Alzheimer Res. 2006 Jul; 3(3):221-7.