"CD4 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.
Descriptor ID |
D015704
|
MeSH Number(s) |
D12.776.543.750.705.852.420.810.500 D12.776.543.750.830.700.025 D23.050.301.264.894.100 D23.101.100.894.100
|
Concept/Terms |
CD4 Antigens- CD4 Antigens
- Antigens, CD4
- CD4 Molecule
- T4 Antigens, T-Cell
- Antigens, T-Cell T4
- T-Cell T4 Antigens
- T4 Antigens, T Cell
- Receptors, CD4
- Surface CD4 Receptor
- CD4 Receptor, Surface
- Receptors, Surface CD4
- CD4 Receptors, Surface
- Surface CD4 Receptors
- CD4 Antigen
- Antigen, CD4
- CD4 Receptors
|
Below are MeSH descriptors whose meaning is more general than "CD4 Antigens".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-16 [D12.776.543.750.705.852.420.810]
- CD4 Antigens [D12.776.543.750.705.852.420.810.500]
- Receptors, Virus [D12.776.543.750.830]
- Receptors, HIV [D12.776.543.750.830.700]
- CD4 Antigens [D12.776.543.750.830.700.025]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- CD4 Antigens [D23.050.301.264.894.100]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- CD4 Antigens [D23.101.100.894.100]
Below are MeSH descriptors whose meaning is more specific than "CD4 Antigens".
This graph shows the total number of publications written about "CD4 Antigens" by people in this website by year, and whether "CD4 Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
1995 | 1 | 2 | 3 |
1997 | 1 | 0 | 1 |
1998 | 0 | 1 | 1 |
1999 | 3 | 3 | 6 |
2000 | 0 | 2 | 2 |
2001 | 0 | 2 | 2 |
2002 | 2 | 1 | 3 |
2003 | 2 | 8 | 10 |
2004 | 0 | 7 | 7 |
2005 | 0 | 2 | 2 |
2006 | 0 | 4 | 4 |
2007 | 2 | 2 | 4 |
2008 | 2 | 5 | 7 |
2009 | 1 | 4 | 5 |
2010 | 3 | 5 | 8 |
2011 | 1 | 0 | 1 |
2012 | 0 | 2 | 2 |
2013 | 1 | 7 | 8 |
2014 | 2 | 2 | 4 |
2015 | 1 | 1 | 2 |
2016 | 0 | 2 | 2 |
2017 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
2019 | 0 | 1 | 1 |
2020 | 2 | 1 | 3 |
2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "CD4 Antigens" by people in Profiles.
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CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021 07; 125(2):176-189.
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Rapamycin Eyedrops Increased CD4+Foxp3+ Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface. Int J Mol Sci. 2020 Nov 24; 21(23).
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CD123+CD4+CD56+ neoplasm: blastic plasmacytoid dendritic cell neoplasm or acute myeloid leukemia? Blood. 2020 09 24; 136(13):1565.
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Epigenetic silencing of CD4 expression in nonpathogenic SIV infection in African green monkeys. JCI Insight. 2020 09 17; 5(18).
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Drug resistance from preferred antiretroviral regimens for HIV infection in South Africa: A modeling study. PLoS One. 2019; 14(7):e0218649.
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Weak Cytotoxic T Cells Activation Predicts Low-Grade Dysplasia Persistence in Ulcerative Colitis. Clin Transl Gastroenterol. 2019 07; 10(7):e00061.
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Engineering multi-specific antibodies against HIV-1. Retrovirology. 2018 08 29; 15(1):60.
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CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema. Nat Commun. 2018 05 17; 9(1):1970.
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Treatment-Na?ve HIV-Infected Patients Have Fewer Gut-Homing ?7 Memory CD4 T Cells than Healthy Controls. South Med J. 2017 11; 110(11):709-713.
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A subset of virus-specific CD161+ T cells selectively express the multidrug transporter MDR1 and are resistant to chemotherapy in AML. Blood. 2017 02 09; 129(6):740-758.