Inducible T-Cell Co-Stimulator Protein
"Inducible T-Cell Co-Stimulator Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory receptor that is specific for INDUCIBLE T-CELL CO-STIMULATOR LIGAND. The receptor is associated with a diverse array of immunologically-related effects including the increased synthesis of INTERLEUKIN 10 in REGULATORY T-LYMPHOCYTES and the induction of PERIPHERAL TOLERANCE.
| Descriptor ID |
D060889
|
| MeSH Number(s) |
D12.776.543.750.705.222.812 D23.050.301.264.894.580 D23.101.100.894.580
|
| Concept/Terms |
Inducible T-Cell Co-Stimulator Protein- Inducible T-Cell Co-Stimulator Protein
- Inducible T Cell Co Stimulator Protein
- Inducible Co-Stimulator (ICOS)
- Inducible T-Cell Co-Stimulator
- Co-Stimulator, Inducible T-Cell
- Inducible T Cell Co Stimulator
- T-Cell Co-Stimulator, Inducible
- Antigens, CD278
- CD278 Antigens
- CD278 Antigen
- Antigen, CD278
- Activation-Inducible Lymphocyte Immunomediatory Molecule
- Activation Inducible Lymphocyte Immunomediatory Molecule
- Inducible Costimulator (ICOS)
- ICOS Inducible T-Cell Co-Stimulator
- ICOS Inducible T Cell Co Stimulator
|
Below are MeSH descriptors whose meaning is more general than "Inducible T-Cell Co-Stimulator Protein".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Costimulatory and Inhibitory T-Cell Receptors [D12.776.543.750.705.222]
- Inducible T-Cell Co-Stimulator Protein [D12.776.543.750.705.222.812]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- Inducible T-Cell Co-Stimulator Protein [D23.050.301.264.894.580]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- Inducible T-Cell Co-Stimulator Protein [D23.101.100.894.580]
Below are MeSH descriptors whose meaning is more specific than "Inducible T-Cell Co-Stimulator Protein".
This graph shows the total number of publications written about "Inducible T-Cell Co-Stimulator Protein" by people in this website by year, and whether "Inducible T-Cell Co-Stimulator Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Inducible T-Cell Co-Stimulator Protein" by people in Profiles.
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ICOS costimulation in combination with CTLA-4 blockade remodels tumor-associated macrophages toward an antitumor phenotype. J Exp Med. 2024 Apr 01; 221(4).
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Recalcitrant Cutaneous Warts in a Family with Inherited ICOS Deficiency. J Invest Dermatol. 2022 09; 142(9):2435-2445.
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Expanding Clinical Phenotype and Novel Insights into the Pathogenesis of ICOS Deficiency. J Clin Immunol. 2020 02; 40(2):277-288.
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Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans. Blood. 2014 Jun 19; 123(25):3988-98.
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TRAF3 regulates the effector function of regulatory T cells and humoral immune responses. J Exp Med. 2014 Jan 13; 211(1):137-51.
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Mesothelin virus-like particle immunization controls pancreatic cancer growth through CD8+ T cell induction and reduction in the frequency of CD4+ foxp3+ ICOS- regulatory T cells. PLoS One. 2013; 8(7):e68303.
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Regulation of natural killer T-cell development by deubiquitinase CYLD. EMBO J. 2010 May 05; 29(9):1600-12.
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CTLA4/ICOS gene variants and haplotypes are associated with rheumatoid arthritis and primary biliary cirrhosis in the Canadian population. Arthritis Rheum. 2009 Apr; 60(4):931-7.
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Expression of ICOS on human melanoma-infiltrating CD4+CD25highFoxp3+ T regulatory cells: implications and impact on tumor-mediated immune suppression. J Immunol. 2008 Mar 01; 180(5):2967-80.
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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol. 2005 Nov; 6(11):1133-41.