Inducible T-Cell Co-Stimulator Protein
"Inducible T-Cell Co-Stimulator Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory receptor that is specific for INDUCIBLE T-CELL CO-STIMULATOR LIGAND. The receptor is associated with a diverse array of immunologically-related effects including the increased synthesis of INTERLEUKIN 10 in REGULATORY T-LYMPHOCYTES and the induction of PERIPHERAL TOLERANCE.
| Descriptor ID |
D060889
|
| MeSH Number(s) |
D12.776.543.750.705.222.812 D23.050.301.264.894.580 D23.101.100.894.580
|
| Concept/Terms |
Inducible T-Cell Co-Stimulator Protein- Inducible T-Cell Co-Stimulator Protein
- Inducible T Cell Co Stimulator Protein
- Inducible Co-Stimulator (ICOS)
- Inducible T-Cell Co-Stimulator
- Co-Stimulator, Inducible T-Cell
- Inducible T Cell Co Stimulator
- T-Cell Co-Stimulator, Inducible
- Antigens, CD278
- CD278 Antigens
- CD278 Antigen
- Antigen, CD278
- Activation-Inducible Lymphocyte Immunomediatory Molecule
- Activation Inducible Lymphocyte Immunomediatory Molecule
- Inducible Costimulator (ICOS)
- ICOS Inducible T-Cell Co-Stimulator
- ICOS Inducible T Cell Co Stimulator
|
Below are MeSH descriptors whose meaning is more general than "Inducible T-Cell Co-Stimulator Protein".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Costimulatory and Inhibitory T-Cell Receptors [D12.776.543.750.705.222]
- Inducible T-Cell Co-Stimulator Protein [D12.776.543.750.705.222.812]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- Inducible T-Cell Co-Stimulator Protein [D23.050.301.264.894.580]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- Inducible T-Cell Co-Stimulator Protein [D23.101.100.894.580]
Below are MeSH descriptors whose meaning is more specific than "Inducible T-Cell Co-Stimulator Protein".
This graph shows the total number of publications written about "Inducible T-Cell Co-Stimulator Protein" by people in this website by year, and whether "Inducible T-Cell Co-Stimulator Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Inducible T-Cell Co-Stimulator Protein" by people in Profiles.
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ICOS costimulation in combination with CTLA-4 blockade remodels tumor-associated macrophages toward an antitumor phenotype. J Exp Med. 2024 Apr 01; 221(4).
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Cardiac computed tomographic imaging in cardio-oncology: An expert consensus document of the Society of Cardiovascular Computed Tomography?(SCCT). Endorsed by the International Cardio-Oncology Society (ICOS). J Cardiovasc Comput Tomogr. 2023 Jan-Feb; 17(1):66-83.
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First-in-Human Phase I/II ICONIC Trial of the ICOS Agonist Vopratelimab Alone and with Nivolumab: ICOS-High CD4 T-Cell Populations and Predictors of Response. Clin Cancer Res. 2022 09 01; 28(17):3695-3708.
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The immunogenomic landscape of resected intrahepatic cholangiocarcinoma. Hepatology. 2022 02; 75(2):297-308.
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Blockade of CTLA-4 and PD-1 Enhances Adoptive T-cell Therapy Efficacy in an ICOS-Mediated Manner. Cancer Immunol Res. 2019 Nov; 7(11):1803-1812.
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Tumor cellular proliferation is associated with enhanced immune checkpoint expression in stage I non-small cell lung cancer. J Thorac Cardiovasc Surg. 2019 09; 158(3):911-919.e6.
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Generation of ROR?t+ Antigen-Specific T Regulatory 17 Cells from Foxp3+ Precursors in Autoimmunity. Cell Rep. 2017 Oct 03; 21(1):195-207.
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Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity. Nat Commun. 2017 02 13; 8:14340.
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IL2 Variant Circumvents ICOS+ Regulatory T-cell Expansion and Promotes NK Cell Activation. Cancer Immunol Res. 2016 11; 4(11):983-994.
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The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development. J Exp Med. 2015 Jun 01; 212(6):865-74.