Costimulatory and Inhibitory T-Cell Receptors
"Costimulatory and Inhibitory T-Cell Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE.
Descriptor ID |
D061025
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MeSH Number(s) |
D12.776.543.750.705.222
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Concept/Terms |
Costimulatory and Inhibitory T-Cell Receptors- Costimulatory and Inhibitory T-Cell Receptors
- Costimulatory and Inhibitory T Cell Receptors
- Costimulatory and Inhibitory T-Lymphocyte Receptors
- Costimulatory and Inhibitory T Lymphocyte Receptors
- Receptors, Costimulatory and Inhibitory, T-Lymphocyte
Costimulatory T-Cell Receptors- Costimulatory T-Cell Receptors
- Costimulatory T Cell Receptors
- Receptors, Costimulatory T-Cell
- T-Cell Receptors, Costimulatory
- Receptors, Costimulatory, T-Lymphocyte
- Costimulatory T-Lymphocyte Receptors
- Costimulatory T Lymphocyte Receptors
- Receptors, Costimulatory T-Lymphocyte
- T-Lymphocyte Receptors, Costimulatory
Inhibitory T-Cell Receptors- Inhibitory T-Cell Receptors
- Inhibitory T Cell Receptors
- Receptors, Inhibitory T-Cell
- T-Cell Receptors, Inhibitory
- Receptors, Inhibitory, T-Cell
- Inhibitory T-Lymphocyte Receptors
- Inhibitory T Lymphocyte Receptors
- Receptors, Inhibitory T-Lymphocyte
- T-Lymphocyte Receptors, Inhibitory
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Below are MeSH descriptors whose meaning is more general than "Costimulatory and Inhibitory T-Cell Receptors".
Below are MeSH descriptors whose meaning is more specific than "Costimulatory and Inhibitory T-Cell Receptors".
This graph shows the total number of publications written about "Costimulatory and Inhibitory T-Cell Receptors" by people in this website by year, and whether "Costimulatory and Inhibitory T-Cell Receptors" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Costimulatory and Inhibitory T-Cell Receptors" by people in Profiles.
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Targeted therapies in metastatic gastric cancer: Current knowledge and future perspectives. World J Gastroenterol. 2019 Oct 14; 25(38):5773-5788.
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Antibody-Based Therapies for Cutaneous T-Cell Lymphoma. Am J Clin Dermatol. 2019 Feb; 20(1):115-122.
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Challenges and Opportunities of Neoadjuvant Treatment in Locally Advanced Melanoma. Am J Clin Dermatol. 2018 Oct; 19(5):639-646.
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Comprehensive immunoproteogenomic analyses of malignant pleural mesothelioma. JCI Insight. 2018 04 05; 3(7).
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Immunotherapy with Checkpoint Blockade in the Treatment of Urothelial Carcinoma. J Urol. 2018 05; 199(5):1129-1142.
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Cancer vaccines in the era of checkpoint blockade: the magic is in the adjuvant. Curr Opin Immunol. 2017 Aug; 47:103-109.
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The emerging role of immune checkpoint based approaches in AML and MDS. Leuk Lymphoma. 2018 04; 59(4):790-802.
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Innovation in Bladder Cancer Immunotherapy. J Immunother. 2016 10; 39(8):291-7.
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The Duality of Fgl2 - Secreted Immune Checkpoint Regulator Versus Membrane-Associated Procoagulant: Therapeutic Potential and Implications. Int Rev Immunol. 2016 07 03; 35(4):325-339.