Receptors, Formyl Peptide
"Receptors, Formyl Peptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class.
| Descriptor ID |
D044042
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| MeSH Number(s) |
D12.776.543.750.695.235 D12.776.543.750.705.873 D12.776.543.750.750.340
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| Concept/Terms |
Receptors, Formyl Peptide- Receptors, Formyl Peptide
- Formyl Peptide Receptors
- Peptide Receptors, Formyl
- FMLP Receptor
- Receptor, FMLP
- N-formyl Hexapeptide Receptor
- Hexapeptide Receptor, N-formyl
- N formyl Hexapeptide Receptor
- Receptor, N-formyl Hexapeptide
- N-Formylmethionyl Peptide Receptor
- N Formylmethionyl Peptide Receptor
- Peptide Receptor, N-Formylmethionyl
- Receptor, N-Formylmethionyl Peptide
- fMet-Leu-Phe Receptor
- Receptor, fMet-Leu-Phe
- fMet Leu Phe Receptor
- Formyl Peptide Receptor
- Receptor, Formyl Peptide
- Receptor, Chemotactic Peptide
- Chemotactic Peptide Receptor
- Peptide Receptor, Chemotactic
- F-Chemotactic Peptide Receptor
- F Chemotactic Peptide Receptor
- Receptor, F-Chemotactic Peptide
- Chemoattractant Receptor
- Receptor, Chemoattractant
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Below are MeSH descriptors whose meaning is more general than "Receptors, Formyl Peptide".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Formyl Peptide".
This graph shows the total number of publications written about "Receptors, Formyl Peptide" by people in this website by year, and whether "Receptors, Formyl Peptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Formyl Peptide" by people in Profiles.
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P2X7R-primed keratinocytes are susceptible to apoptosis via GPCR-G??-pERK signal pathways. J Dermatol Sci. 2024 Dec; 116(3):90-99.
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Synergetic Roles of Formyl Peptide Receptor 1 Oligomerization in Ligand-Induced Signal Transduction. ACS Chem Biol. 2020 09 18; 15(9):2577-2587.
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Differential expression of the G-protein-coupled formyl Peptide receptor in melanoma associates with aggressive phenotype. Am J Dermatopathol. 2013 Apr; 35(2):184-90.
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Up-regulation of Annexin-A1 and lipoxin A(4) in individuals with ulcerative colitis may promote mucosal homeostasis. PLoS One. 2012; 7(6):e39244.
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Serum amyloid A, but not C-reactive protein, stimulates vascular proteoglycan synthesis in a pro-atherogenic manner. Am J Pathol. 2008 Dec; 173(6):1902-10.
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Activation of the formyl peptide receptor by the HIV-derived peptide T-20 suppresses interleukin-12 p70 production by human monocytes. Blood. 2001 Jun 01; 97(11):3531-6.
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Monocytes express a non-neurokinin substance P receptor that is functionally coupled to MAP kinase. J Immunol. 1994 Mar 15; 152(6):2987-94.
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Subcellular distribution and characterization of GTP-binding proteins in human neutrophils. Biochim Biophys Acta. 1990 Sep 01; 1054(2):237-45.
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Solubilization and reconstitution of the formylmethionylleucylphenylalanine receptor coupled to guanine nucleotide regulatory protein. Biochemistry. 1988 Jul 12; 27(14):5371-7.