"Frizzled Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 to form receptors for WNT PROTEINS. Frizzled receptors often couple with HETEROTRIMERIC G PROTEINS and regulate the WNT SIGNALING PATHWAY.
| Descriptor ID |
D051157
|
| MeSH Number(s) |
D12.776.543.750.695.017 D12.776.543.750.850.500
|
| Concept/Terms |
Frizzled Receptors- Frizzled Receptors
- Frizzled Receptor
- Receptor, Frizzled
- Receptors, Frizzled
- Frizzled Proteins
|
Below are MeSH descriptors whose meaning is more general than "Frizzled Receptors".
Below are MeSH descriptors whose meaning is more specific than "Frizzled Receptors".
This graph shows the total number of publications written about "Frizzled Receptors" by people in this website by year, and whether "Frizzled Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Frizzled Receptors" by people in Profiles.
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Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects. Hum Genet. 2020 Oct; 139(10):1299-1314.
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A miR-SNP biomarker linked to an increased lung cancer survival by miRNA-mediated down-regulation of FZD4 expression and Wnt signaling. Sci Rep. 2017 08 22; 7(1):9029.
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A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Commun. 2016 10 04; 7:12885.
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Next-generation sequencing and novel variant determination in a cohort of 92 familial exudative vitreoretinopathy patients. Invest Ophthalmol Vis Sci. 2015 Feb 24; 56(3):1937-46.
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Inhibitory effect of 2-(piperidinoethoxyphenyl)-3-(4-hydroxyphenyl)-2H-benzo(b)pyran (K-1) on human primary endometrial hyperplasial cells mediated via combined suppression of Wnt/?-catenin signaling and PI3K/Akt survival pathway. Cell Death Dis. 2014 Aug 21; 5:e1380.
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WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors. J Clin Invest. 2014 Jul; 124(7):2877-90.
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FZD1 regulates cumulus expansion genes and is required for normal female fertility in mice. Biol Reprod. 2012 Nov; 87(5):104.
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WNTs in the neonatal mouse uterus: potential regulation of endometrial gland development. Biol Reprod. 2011 Feb; 84(2):308-19.
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WNT signaling in ovarian follicle biology and tumorigenesis. Trends Endocrinol Metab. 2010 Jan; 21(1):25-32.
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A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration. Nat Genet. 2008 Jul; 40(7):862-70.