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RICHARD FINNELL

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
Address6501 Fannin St
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Precision Environmental Health
    DivisionCenter for Precision Env Health

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-General Medicine


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    R01HD113702     (CORRADETTI, BRUNA)Sep 1, 2024 - May 31, 2029
    NIH
    Biomimetic intervention strategies for endogenous in utero repair of Spina Bifida
    Role: Co-Principal Investigator
    R13HD116494     (FINNELL, RICHARD H.)Aug 1, 2024 - Jul 31, 2025
    NIH
    The 13th International Conference on Neural Tube Defects
    Role: Principal Investigator
    R01HD111089     (ROSS, MARGARET ELIZABETH)Sep 12, 2023 - Aug 31, 2028
    NIH
    Understanding Genetic Complexity in Spina Bifida
    Role: Co-Principal Investigator
    R01HD098131     (PARCHEM, RONALD J)Mar 10, 2020 - Feb 28, 2025
    NIH
    MicroRNA regulation of neural tube closure
    Role: Co-Principal Investigator
    R01HD100535     (LEI, YUNPING)Mar 10, 2020 - Feb 28, 2025
    NIH
    Role of Slc25a32 and Its Interaction with Lrp6 in the Etiology of Neural Tube Defects
    Role: Co-Principal Investigator
    R01HD095520     (FINNELL, RICHARD H.;LARIN, KIRILL V ;SCARCELLI, GIULIANO)Sep 1, 2018 - Jun 30, 2024
    NIH
    Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality
    Role: Co-Principal Investigator
    R01HD093758     (FINNELL, RICHARD H. ;KIM, SUNG EUN)Sep 1, 2018 - Jun 30, 2023
    NIH
    The Role of GPR161 in the Etiology of Neural Tube Defects
    Role: Principal Investigator
    R13HD093414     (FINNELL, RICHARD H.)Jul 16, 2017 - Jun 30, 2018
    NIH
    2017 10th International Conference on Neural Tube Defects
    Role: Principal Investigator
    R01HD083809     (FINNELL, RICHARD H.)Feb 15, 2016 - Jul 31, 2025
    NIH
    INTERVENTION STRATEGIES FOR NON-FOLATE RESPONSIVE NEURAL TUBE DEFECTS
    Role: Principal Investigator
    R01HD081216     (FINNELL, RICHARD H.)Aug 10, 2015 - Jun 30, 2021
    NIH
    Folic Acid, Parental Mutation Rates and the Risk for Neural Tube Defects
    Role: Principal Investigator
    R13HD084156     (FINNELL, RICHARD H.)Aug 1, 2015 - Jul 31, 2016
    NIH
    2015 International Conference on Neural Tube Defects
    Role: Principal Investigator
    R01ES021006     (FINNELL, RICHARD H.)Aug 16, 2012 - Jun 30, 2016
    NIH
    Study of Neural Tube Defects Etiology: Genome and Exposome
    Role: Principal Investigator
    R21HD072251     (FINNELL, RICHARD H.)Aug 1, 2012 - Jul 31, 2014
    NIH
    Genetic Regulation of Valproic Acid Teratogenicity
    Role: Principal Investigator
    U13DP003269     (FINNELL, RICHARD H.)Sep 30, 2011 - Sep 29, 2016
    NIH
    7TH INTERNATIONAL CONFERENCE ON NEURAL TUBE DEFECTS (NTDS)
    Role: Principal Investigator
    R13NS066584     (FINNELL, RICHARD H.)Jul 1, 2009 - Jun 30, 2010
    NIH
    Sixth International Neural Tube Defects Conference
    Role: Principal Investigator
    R01DE016315     (FINNELL, RICHARD H.)Aug 1, 2005 - Oct 30, 2010
    NIH
    GENETIC REGULATION OF FOLATE RESPONSIVE BIRTH DEFECTS
    Role: Principal Investigator
    R01DE013613     (FINNELL, RICHARD H.)May 1, 1999 - Apr 30, 2004
    NIH
    FOLATE RECEPTORS IN CRANIOFACIAL MALFORMATIONS
    Role: Principal Investigator
    R01HD035396     (FINNELL, RICHARD H.)Apr 1, 1997 - Mar 31, 2002
    NIH
    FOLATE RECEPTOR KNOCKOUTS, ARSENATE AND BIRTH DEFECTS
    Role: Principal Investigator
    R01ES007165     (FINNELL, RICHARD H.)Jul 1, 1994 - Jun 30, 1998
    NIH
    GENE EXPRESSION DURING MURINE NEURAL TUBE CLOSURE
    Role: Principal Investigator
    R01DE011303     (FINNELL, RICHARD H.)May 1, 1994 - Apr 30, 1999
    NIH
    ANTIEPILETIC DRUG SYNDROME--A MOLECULAR ANALYSIS
    Role: Principal Investigator
    R01ES004326     (FINNELL, RICHARD H.)Jan 15, 1988 - Jun 30, 1991
    NIH
    THE HEAT SHOCK RESPONSE: POTENTIAL TO SCREEN TERATOGENS
    Role: Principal Investigator
    R03MH042149     (FINNELL, RICHARD H.)Aug 1, 1986 - Jul 31, 1987
    NIH
    HEAT SHOCK PROTEINS AND ABNORMAL NEURAL DEVELOPMENT
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li H, Ma Q, Xue Y, Cai L, Bao L, Hong L, Zeng Y, Huang SZ, Finnell RH, Zeng F. Compound heterozygous mutation of AFG3L2 causes autosomal recessive spinocerebellar ataxia through mitochondrial impairment and MICU1 mediated Ca2+ overload. Sci China Life Sci. 2024 Oct 11. PMID: 39428429.
      Citations:    Fields:    
    2. Kim SE, Kim HY, Wlodarczyk BJ, Finnell RH. Linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse neural tube development. Development. 2024 Oct 01; 151(19). PMID: 39369306; PMCID: PMC11463954.
      Citations:    Fields:    Translation:AnimalsCells
    3. Vaiasicca S, Melone G, James DW, Quintela M, Xiao J, Yao S, Finnell RH, Conlan RS, Francis LW, Corradetti B, Vaiasicca S, Melone G, James DW, Quintela M, Xiao J, Yao S, Finnell RH, Conlan RS, Francis LW, Corradetti B. Transcriptomic analysis reveals the anti-cancer effect of gestational mesenchymal stem cell secretome. Stem Cells Transl Med. 2024 Jul 15; 13(7):693-710. PMID: 38584493; PMCID: PMC11227973.
      Citations:    Fields:    Translation:HumansCells
    4. Steele JW, Krishnan V, Finnell RH. Mechanisms of neurodevelopmental toxicity of topiramate. Crit Rev Toxicol. 2024 Aug; 54(7):465-475. PMID: 38995641; PMCID: PMC11296906.
      Citations:    Fields:    Translation:HumansAnimals
    5. van der Veer BK, Chen L, Tsaniras SC, Brangers W, Chen Q, Schroiff M, Custers C, Kwak HHM, Khoueiry R, Cabrera R, Gross SS, Finnell RH, Lei Y, Koh KP, van der Veer BK, Chen L, Tsaniras SC, Brangers W, Chen Q, Schroiff M, Custers C, Kwak HHM, Khoueiry R, Cabrera R, Gross SS, Finnell RH, Lei Y, Koh KP. Epigenetic regulation by TET1 in gene-environmental interactions influencing susceptibility to congenital malformations. bioRxiv. 2024 Jul 08. PMID: 39026762; PMCID: PMC11257484.
      Citations:    
    6. Blue EE, Moore KJ, North KE, Desrosiers TA, Carmichael SL, White JJ, Chong JX, Bamshad MJ, Jenkins MM, Almli LM, Brody LC, Freedman SF, Reefhuis J, Romitti PA, Shaw GM, Werler M, Kay DM, Browne ML, Feldkamp ML, Finnell RH, Nembhard WN, Pangilinan F, Olshan AF, National Institutes of Health Intramural Sequencing Center, University of Washington Center for Mendelian Genomics, National Birth Defects Prevention Study. Exome sequencing identifies novel genes underlying primary congenital glaucoma in the National Birth Defects Prevention Study. Birth Defects Res. 2024 Jul; 116(7):e2384. PMID: 38990107; PMCID: PMC11245170.
      Citations:    Fields:    Translation:Humans
    7. Fonteles CSR, Steele JW, Idowu DI, Burgelin B, Finnell RH, Corradetti B. Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations. Res Sq. 2024 Jun 04. PMID: 38883749; PMCID: PMC11177991.
      Citations:    
    8. Pimienta Ramirez PA, Han X, Schatz UA, Shoukier M, Rieger-Fackeldey E, Ortiz JU, Finnell RH, Lei Y, de Koning MA, Haak MC, Ruiterkamp-Versteeg MH, de Leeuw N, van Duinen SG, Klein WM, Witlox RSGM, Santen GWE, Suerink M. De novo heterozygous missense variants in CELSR1 as cause of fetal pleural effusions and progressive fetal hydrops. J Med Genet. 2024 May 21; 61(6):549-552. PMID: 38272662.
      Citations:    Fields:    Translation:Humans
    9. Caiaffa CD, Tukeman G, Delgado CZ, Ambekar YS, Mekonnen TT, Singh M, Rodriguez V, Ricco E, Kraushaar D, Aglyamov SR, Scarcelli G, Larin KV, Finnell RH, Cabrera RM. Dolutegravir induces FOLR1 expression during brain organoid development. Front Mol Neurosci. 2024; 17:1394058. PMID: 38828282; PMCID: PMC11140035.
      Citations: 1     
    10. Nicoletti P, Zafer S, Matok L, Irron I, Patrick M, Haklai R, Evangelista JE, Marino GB, Ma'ayan A, Sewda A, Holmes G, Britton SR, Lee WJ, Wu M, Ru Y, Arnaud E, Botto L, Brody LC, Byren JC, Caggana M, Carmichael SL, Cilliers D, Conway K, Crawford K, Cuellar A, Di Rocco F, Engel M, Fearon J, Feldkamp ML, Finnell R, Fisher S, Freudlsperger C, Garcia-Fructuoso G, Hagge R, Heuz? Y, Harshbarger RJ, Hobbs C, Howley M, Jenkins MM, Johnson D, Justice CM, Kane A, Kay D, Gosain AK, Langlois P, Legal-Mallet L, Lin AE, Mills JL, Morton JEV, Noons P, Olshan A, Persing J, Phipps JM, Redett R, Reefhuis J, Rizk E, Samson TD, Shaw GM, Sicko R, Smith N, Staffenberg D, Stoler J, Sweeney E, Taub PJ, Timberlake AT, Topczewska J, Wall SA, Wilson AF, Wilson LC, Boyadjiev SA, Wilkie AOM, Richtsmeier JT, Jabs EW, Romitti PA, Karasik D, Birnbaum RY, Peter I. Regulatory elements in SEM1-DLX5-DLX6 (7q21.3) locus contribute to genetic control of coronal nonsyndromic craniosynostosis and bone density-related traits. Genet Med Open. 2024; 2. PMID: 39345948; PMCID: PMC11434253.
      Citations:    
    11. Ambekar YS, Caiaffa CD, Wlodarczyk BJ, Singh M, Schill AW, Steele JW, Zhang J, Aglyamov SR, Scarcelli G, Finnell RH, Larin KV. Optical coherence tomography-guided Brillouin microscopy highlights regional tissue stiffness differences during anterior neural tube closure in the Mthfd1l murine mutant. Development. 2024 May 15; 151(10). PMID: 38682273; PMCID: PMC11165724.
      Citations:    Fields:    Translation:Animals
    12. Vong KI, Lee S, Au KS, Crowley TB, Capra V, Martino J, Haller M, Ara?jo C, Machado HR, George R, Gerding B, James KN, Stanley V, Jiang N, Alu K, Meave N, Nidhiry AS, Jiwani F, Tang I, Nisal A, Jhamb I, Patel A, Patel A, McEvoy-Venneri J, Barrows C, Shen C, Ha YJ, Howarth R, Strain M, Ashley-Koch AE, Azam M, Mumtaz S, Bot GM, Finnell RH, Kibar Z, Marwan AI, Melikishvili G, Meltzer HS, Mutchinick OM, Stevenson DA, Mroczkowski HJ, Ostrander B, Schindewolf E, Moldenhauer J, Zackai EH, Emanuel BS, Garcia-Minaur S, Nowakowska BA, Stevenson RE, Zaki MS, Northrup H, McNamara HK, Aldinger KA, Phelps IG, Deng M, Glass IA, Spina Bifida Sequencing Consortium?, Morrow B, McDonald-McGinn DM, Sanna-Cherchi S, Lamb DJ, Gleeson JG. Risk of meningomyelocele mediated by the common 22q11.2 deletion. Science. 2024 05 03; 384(6695):584-590. PMID: 38696583.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    13. Caiaffa CD, Ambekar YS, Singh M, Lin YL, Wlodarczyk B, Aglyamov SR, Scarcelli G, Larin KV, Finnell RH. Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve ganglia. Dev Dyn. 2024 Mar 19. PMID: 38501709; PMCID: PMC11411014.
      Citations:    Fields:    
    14. Lu L, Bai M, Zheng Y, Wang X, Chen Z, Peng R, Finnell RH, Zhao T, Li C, Wu B, Lei Y, Li J, Wang H, Finnell RH, Lei Y. The interaction of endorepellin and neurexin triggers neuroepithelial autophagy and maintains neural tube development. Sci Bull (Beijing). 2024 Jul 30; 69(14):2260-2272. PMID: 38702277.
      Citations:    Fields:    Translation:HumansAnimalsCells
    15. Tukeman GL, Wei H, Lin YL, Wlodarczyk BJ, Finnell RH, Cabrera RM. Dolutegravir-induced neural tube defects in mice are folate responsive. AIDS. 2024 03 15; 38(4):439-446. PMID: 37382903; PMCID: PMC10755062.
      Citations: 1     Fields:    Translation:HumansAnimals
    16. V RP, Finnell RH, Ross ME, Alarc?n P, Suazo J. Neural tube defects and epigenetics: role of histone post-translational histone modifications. Epigenomics. 2024 Mar; 16(6):419-426. PMID: 38410929.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    17. Chen Z, Finnell RH, Lei Y, Wang H. Progress and clinical prospect of genomic structural variants investigation. Sci Bull (Beijing). 2024 Mar 30; 69(6):705-708. PMID: 38310047.
      Citations: 1     Fields:    
    18. Kim SE, Kim HY, Wlodarczyk BJ, Finnell RH. The novel linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse embryonic development. bioRxiv. 2024 Jan 12. PMID: 38260275; PMCID: PMC10802560.
      Citations:    
    19. Han X, Cao X, Cabrera RM, Ramirez PAP, Lin YL, Wlodarczyk BJ, Zhang C, Finnell RH, Lei Y. Folate regulation of planar cell polarity pathway and F-actin through folate receptor alpha. FASEB J. 2024 01; 38(1):e23346. PMID: 38095297; PMCID: PMC10754249.
      Citations: 1     Fields:    Translation:AnimalsCells
    20. Finnell RH, Zhu H. Periconceptional maternal folate supplementation impacts a diverse range of congenital malformations. Pediatr Res. 2024 Mar; 95(4):880-882. PMID: 38030827.
      Citations:    Fields:    
    21. Kim SE, Chothani PJ, Shaik R, Pollard W, Finnell RH. Pax3 lineage-specific deletion of Gpr161 is associated with spinal neural tube and craniofacial malformations during embryonic development. Dis Model Mech. 2023 Nov 01; 16(11). PMID: 37885410; PMCID: PMC10694864.
      Citations: 1     Fields:    Translation:AnimalsCells
    22. Alfar R, Napoleon JV, Shahriar I, Finnell R, Walchle C, Johnson A, Low PS. Selective reprogramming of regulatory T cells in solid tumors can strongly enhance or inhibit tumor growth. Front Immunol. 2023; 14:1274199. PMID: 37928524; PMCID: PMC10623129.
      Citations:    Fields:    Translation:HumansAnimalsCells
    23. Chen S, Lei Y, Yang Y, Liu C, Kuang L, Jin L, Finnell RH, Yang X, Wang H. A mutation in TBXT causes congenital vertebral malformations in?humans and mice. J Genet Genomics. 2024 Apr; 51(4):433-442. PMID: 37751845.
      Citations: 1     Fields:    
    24. Vaiasicca S, Melone G, James DW, Quintela M, Preziuso A, Finnell RH, Conlan RS, Francis LW, Corradetti B. Transcriptomic analysis of stem cells from chorionic villi uncovers the impact of chromosomes 2, 6 and 22 in the clinical manifestations of Down syndrome. Stem Cell Res Ther. 2023 09 23; 14(1):265. PMID: 37740230; PMCID: PMC10517537.
      Citations:    Fields:    Translation:HumansCells
    25. Genomics England Research Consortium, Crane-Smith Z, De Castro SCP, Nikolopoulou E, Wolujewicz P, Smedley D, Lei Y, Mather E, Santos C, Hopkinson M, Pitsillides AA, Finnell RH, Ross ME, Copp AJ, Greene NDE. A non-coding insertional mutation of Grhl2 causes gene over-expression and multiple structural anomalies including cleft palate, spina bifida and encephalocele. Hum Mol Genet. 2023 08 26; 32(17):2681-2692. PMID: 37364051; PMCID: PMC10460492.
      Citations:    Fields:    Translation:HumansAnimals
    26. Caiaffa CD, Ambekar YS, Singh M, Lin YL, Wlodarczyk B, Aglyamov SR, Scarcelli G, Larin KV, Finnell R. Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve ganglia. bioRxiv. 2023 Aug 04. PMID: 37577618; PMCID: PMC10418252.
      Citations:    
    27. Keuls RA, Finnell RH, Parchem RJ. Maternal metabolism influences neural tube closure. Trends Endocrinol Metab. 2023 09; 34(9):539-553. PMID: 37468429; PMCID: PMC10529122.
      Citations: 2     Fields:    Translation:Humans
    28. Kim SE, Chothani PJ, Shaik R, Pollard W, Finnell RH. Pax3 lineage-specific deletion of Gpr161 is associated with spinal neural tube and craniofacial malformations during embryonic development. bioRxiv. 2023 Jul 07. PMID: 37461574; PMCID: PMC10350067.
      Citations:    
    29. van der Veer BK, Chen L, Custers C, Athanasouli P, Schroiff M, Cornelis R, Chui JS, Finnell RH, Lluis F, Koh KP. Dual functions of TET1 in germ layer lineage bifurcation distinguished by genomic context and dependence on 5-methylcytosine oxidation. Nucleic Acids Res. 2023 06 23; 51(11):5469-5498. PMID: 37021585; PMCID: PMC10287924.
      Citations:    Fields:    Translation:Animals
    30. Chen Z, Lei Y, Finnell RH, Ding Y, Su Z, Wang Y, Xie H, Chen F. Whole-exome sequencing study of hypospadias. iScience. 2023 May 19; 26(5):106663. PMID: 37168556; PMCID: PMC10165268.
      Citations: 2     
    31. Pastora Bucardo DM, Gonz?lez F, Montes Pastora M, Pimienta Ramirez PA, Bonilla IL, Vielot NA, Finnell RH. Neural tube defects: Prevalence, mortality, and maternal characteristics in two departmental hospitals in the northwestern region of Nicaragua, 2006-2018. Birth Defects Res. 2023 05 15; 115(9):945-953. PMID: 37025002.
      Citations:    Fields:    Translation:Humans
    32. Sok P, Sabo A, Almli LM, Jenkins MM, Nembhard WN, Agopian AJ, Bamshad MJ, Blue EE, Brody LC, Brown AL, Browne ML, Canfield MA, Carmichael SL, Chong JX, Dugan-Perez S, Feldkamp ML, Finnell RH, Gibbs RA, Kay DM, Lei Y, Meng Q, Moore CA, Mullikin JC, Muzny D, Olshan AF, Pangilinan F, Reefhuis J, Romitti PA, Schraw JM, Shaw GM, Werler MM, Harpavat S, Lupo PJ, University of Washington Center for Mendelian Genomics, NISC Comparative Sequencing Program, the Nat. Exome-wide assessment of isolated biliary atresia: A report from the National Birth Defects Prevention Study using child-parent trios and a case-control design to identify novel rare variants. Am J Med Genet A. 2023 06; 191(6):1546-1556. PMID: 36942736; PMCID: PMC10947986.
      Citations:    Fields:    Translation:Humans
    33. Cao X, Xu J, Lin YL, Cabrera RM, Chen Q, Zhang C, Steele JW, Han X, Gross SS, Wlodarczyk BJ, Lupski JR, Li W, Wang H, Finnell RH, Lei Y. Excess folic acid intake increases DNA de novo point mutations. Cell Discov. 2023 Feb 28; 9(1):22. PMID: 36849450; PMCID: PMC9970956.
      Citations: 4     
    34. Cano A, Vazquez-Chantada M, Conde-Vancells J, Gonzalez-Lahera A, Mosen-Ansorena D, Blanco FJ, Cl?ment K, Aron-Wisnewsky J, Tran A, Gual P, Garc?a-Monz?n C, Caballer?a J, Castro A, Mart?nez-Chantar ML, Mato JM, Zhu H, Finnell RH, Aransay AM. Impaired Function of Solute Carrier Family 19 Leads to Low Folate Levels and Lipid Droplet Accumulation in Hepatocytes. Biomedicines. 2023 Jan 31; 11(2). PMID: 36830876; PMCID: PMC9953281.
      Citations:    
    35. Han X, Cao X, Cabrera RM, Pimienta Ramirez PA, Zhang C, Ramaekers VT, Finnell RH, Lei Y. KDM6B Variants May Contribute to the Pathophysiology of Human Cerebral Folate Deficiency. Biology (Basel). 2022 Dec 31; 12(1). PMID: 36671766; PMCID: PMC9855468.
      Citations: 3     
    36. Caiaffa CD, Fonteles CSR, Yunping L, Finnell RH. Gene-environment interactions underlying the etiology of neural tube defects. Curr Top Dev Biol. 2023; 152:193-220. PMID: 36707212.
      Citations:    Fields:    Translation:Humans
    37. Iskandar BJ, Finnell RH. Spina Bifida. Reply. N Engl J Med. 2022 10 27; 387(17):1628. PMID: 36300989.
      Citations: 1     Fields:    Translation:Humans
    38. Han X, Cao X, Aguiar-Pulido V, Yang W, Karki M, Ramirez PAP, Cabrera RM, Lin YL, Wlodarczyk BJ, Shaw GM, Ross ME, Zhang C, Finnell RH, Lei Y. CIC missense variants contribute to susceptibility for spina bifida. Hum Mutat. 2022 12; 43(12):2021-2032. PMID: 36054333; PMCID: PMC9772115.
      Citations:    
    39. Mohan Dass NL, Botto LD, Tinker SC, Canfield MA, Finnell RH, Gallaway MS, Hashmi SS, Hoyt AT, Nembhard WN, Waller DK, National Birth Defects Prevention Study. Associations between maternal reports of periconceptional fever from miscellaneous causes and structural birth defects. Birth Defects Res. 2022 09 01; 114(15):885-894. PMID: 35932236; PMCID: PMC10580304.
      Citations:    
    40. Iskandar BJ, Finnell RH. Spina Bifida. N Engl J Med. 2022 08 04; 387(5):444-450. PMID: 35921452.
      Citations:    
    41. Li J, Yang W, Wang YJ, Ma C, Curry CJ, McGoldrick D, Nickerson DA, Chong JX, Blue EE, Mullikin JC, Reefhuis J, Nembhard WN, Romitti PA, Werler MM, Browne ML, Olshan AF, Finnell RH, Feldkamp ML, Pangilinan F, Almli LM, Bamshad MJ, Brody LC, Jenkins MM, Shaw GM, NISC Comparative Sequencing Program, University of Washington Center for Mendelian Genomics, National Birth Defects Prevention Study. Exome sequencing identifies genetic variants in anophthalmia and microphthalmia. Am J Med Genet A. 2022 08; 188(8):2376-2388. PMID: 35716026; PMCID: PMC9283271.
      Citations:    Fields:    Translation:Humans
    42. Ambekar YS, Singh M, Schill AW, Zhang J, Zevallos-Delgado C, Khajavi B, Aglyamov SR, Finnell RH, Scarcelli G, Larin KV. Multimodal imaging system combining optical coherence tomography and Brillouin microscopy for neural tube imaging. Opt Lett. 2022 Mar 15; 47(6):1347-1350. PMID: 35290310; PMCID: PMC9088521.
      Citations:    Fields:    Translation:Animals
    43. Pitsava G, Feldkamp ML, Pankratz N, Lane J, Kay DM, Conway KM, Hobbs C, Shaw GM, Reefhuis J, Jenkins MM, Almli LM, Moore C, Werler M, Browne ML, Cunniff C, Olshan AF, Pangilinan F, Brody LC, Sicko RJ, Finnell RH, Bamshad MJ, McGoldrick D, Nickerson DA, Mullikin JC, Romitti PA, Mills JL, UW Center for Mendelian Genomics, NISC Comparative Sequencing Program and the National Birth Defects. Exome sequencing identifies variants in infants with sacral agenesis. Birth Defects Res. 2022 04; 114(7):215-227. PMID: 35274497; PMCID: PMC9338687.
      Citations:    Fields:    Translation:Humans
    44. Steele JW, Lin YL, Chen N, Wlodarczyk BJ, Chen Q, Attarwala N, Venkatesalu M, Cabrera RM, Gross SS, Finnell RH. Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects. Front Cell Dev Biol. 2022; 10:832492. PMID: 35265619; PMCID: PMC8898900.
      Citations:    
    45. Aguiar-Pulido V, Wolujewicz P, Martinez-Fundichely A, Elhaik E, Thareja G, Abdel Aleem A, Chalhoub N, Cuykendall T, Al-Zamer J, Lei Y, El-Bashir H, Musser JM, Al-Kaabi A, Shaw GM, Khurana E, Suhre K, Mason CE, Elemento O, Finnell RH, Ross ME. Systems biology analysis of human genomes points to key pathways conferring spina bifida risk. Proc Natl Acad Sci U S A. 2021 12 21; 118(51). PMID: 34916285; PMCID: PMC8713748.
      Citations: 1     Fields:    Translation:Humans
    46. Kim SE, Robles-Lopez K, Cao X, Liu K, Chothani PJ, Bhavani N, Rahman L, Mukhopadhyay S, Wlodarczyk BJ, Finnell RH. Wnt1 Lineage Specific Deletion of Gpr161 Results in Embryonic Midbrain Malformation and Failure of Craniofacial Skeletal Development. Front Genet. 2021; 12:761418. PMID: 34887903; PMCID: PMC8650154.
      Citations:    
    47. Wolujewicz P, Steele JW, Kaltschmidt JA, Finnell RH, Ross ME. Unraveling the complex genetics of neural tube defects: From biological models to human genomics and back. Genesis. 2021 11; 59(11):e23459. PMID: 34713546; PMCID: PMC8851409.
      Citations: 2     Fields:    Translation:HumansAnimals
    48. Finnell RH, Lei Y, Zurita-Jimenez ME, George TM, Harshbarger RJ, Fonteles CS, Monteiro AJ. De novo ALX4 variant detected in child with non-syndromic craniosynostosis. Braz J Med Biol Res. 2021; 54(11):e11396. PMID: 34586326.
      Citations:    Fields:    Translation:HumansCells
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    114. Lu HC, Tan Q, Rousseaux MW, Wang W, Kim JY, Richman R, Wan YW, Yeh SY, Patel JM, Liu X, Lin T, Lee Y, Fryer JD, Han J, Chahrour M, Finnell RH, Lei Y, Zurita-Jimenez ME, Ahimaz P, Anyane-Yeboa K, Lehalle D, Jean-Marcais N, Mosca-Boidron AL, Thevenon J, Cousin MA, Bro DE, Lanpher BC, Klee EW, Alexander N, Bainbridge MN, Orr HT, Sillitoe RV, Ljungberg MC, Liu Z, Schaaf CP, Zoghbi HY, Van Maldergem L. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 Apr; 49(4):527-536. PMID: 28288114; PMCID: PMC5374026.
      Citations: 49     Fields:    Translation:HumansAnimals
    115. Bibi D, Mawasi H, Wlodarczyk B, Finnell RH, Bialer M, Nocentini A, Supuran CT. Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide. Neurochem Res. 2017 Jul; 42(7):1972-1982. PMID: 28275953.
      Citations: 3     Fields:    Translation:Animals
    116. Chen X, An Y, Gao Y, Guo L, Rui L, Xie H, Sun M, Lam Hung S, Sheng X, Zou J, Bao Y, Guan H, Niu B, Li Z, Finnell RH, Gusella JF, Wu BL, Zhang T. Rare Deleterious PARD3 Variants in the aPKC-Binding Region are Implicated in the Pathogenesis of Human Cranial Neural Tube Defects Via Disrupting Apical Tight Junction Formation. Hum Mutat. 2017 04; 38(4):378-389. PMID: 27925688; PMCID: PMC5513730.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    117. Akimova D, Wlodarczyk BJ, Lin Y, Ross ME, Finnell RH, Chen Q, Gross SS. Metabolite profiling of whole murine embryos reveals metabolic perturbations associated with maternal valproate-induced neural tube closure defects. Birth Defects Res. 2017 01 30; 109(2):106-119. PMID: 27860192; PMCID: PMC5388579.
      Citations: 4     Fields:    Translation:Animals
    118. Ross ME, Mason CE, Finnell RH. Genomic approaches to the assessment of human spina bifida risk. Birth Defects Res. 2017 01 30; 109(2):120-128. PMID: 27883265; PMCID: PMC5388593.
      Citations: 9     Fields:    Translation:Humans
    119. Bayer CL, Wlodarczyk BJ, Finnell RH, Emelianov SY. Ultrasound-guided spectral photoacoustic imaging of hemoglobin oxygenation during development. Biomed Opt Express. 2017 Feb 01; 8(2):757-763. PMID: 28270982; PMCID: PMC5330552.
      Citations: 12     
    120. Yang N, Wang L, Finnell RH, Li Z, Jin L, Zhang L, Cabrera RM, Ye R, Ren A. Corrigendum for: Levels of folate receptor autoantibodies in maternal and cord blood and risk of neural tube defects in a Chinese population, 106:685-695 (10.1002/bdra.23517). Birth Defects Res A Clin Mol Teratol. 2016 12; 106(12):1062. PMID: 28000437.
      Citations:    Fields:    
    121. McCollum CW, Conde-Vancells J, Hans C, Vazquez-Chantada M, Kleinstreuer N, Tal T, Knudsen T, Shah SS, Merchant FA, Finnell RH, Cabrera R, Bondesson M, Gustafsson J?. Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells. Reprod Toxicol. 2017 06; 70:60-69. PMID: 27838387; PMCID: PMC5425326.
      Citations: 8     Fields:    Translation:AnimalsCells
    122. Qiao X, Liu Y, Li P, Chen Z, Li H, Yang X, Finnell RH, Yang Z, Zhang T, Qiao B, Zheng Y, Wang H. Genetic analysis of rare coding mutations of CELSR1-3 in congenital heart and neural tube defects in Chinese people. Clin Sci (Lond). 2016 Dec 01; 130(24):2329-2340. PMID: 27756857.
      Citations: 15     Fields:    
    123. d'Esposito AM, Kolatsi-Joannou M, Patel V, Igarashi P, Lei Y, Finnell RH, Lythgoe MF, Woolf AS, Papakrivopoulou E, Long DA, Brz?ska HL. Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning. Kidney Int. 2016 12; 90(6):1274-1284. PMID: 27597235; PMCID: PMC5126096.
      Citations: 17     Fields:    Translation:HumansAnimals
    124. Finnell RH, Shaw GM. Remembering Edward J. Lammer, MD. Am J Med Genet A. 2016 Nov; 170(11):2767-2768. PMID: 27481654.
      Citations:    Fields:    
    125. Yang N, Wang L, Finnell RH, Li Z, Jin L, Zhang L, Cabrera RM, Ye R, Ren A. Levels of folate receptor autoantibodies in maternal and cord blood and risk of neural tube defects in a Chinese population. Birth Defects Res A Clin Mol Teratol. 2016 Aug; 106(8):685-95. PMID: 27166990; PMCID: PMC4983204.
      Citations: 7     Fields:    Translation:Humans
    126. Denny KJ, Kelly CF, Kumar V, Witham KL, Cabrera RM, Finnell RH, Taylor SM, Jeanes A, Woodruff TM. Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects. Birth Defects Res A Clin Mol Teratol. 2016 Mar; 106(3):201-7. PMID: 26900104; PMCID: PMC4801756.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    127. Lei Y, Finnell RH. New Techniques for the Study of Neural Tube Defects. Adv Tech Biol Med. 2016 Feb; 4(1). PMID: 27066597; PMCID: PMC4826067.
      Citations: 4     
    128. Hill DS, Cabrera R, Wallis Schultz D, Zhu H, Lu W, Finnell RH, Wlodarczyk BJ. Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences of In Utero Exposure to Environmental Pollutants in a Mouse Model. Behav Neurol. 2015; 2015:426263. PMID: 26586927; PMCID: PMC4637446.
      Citations: 17     Fields:    Translation:Animals
    129. Wlodarczyk BJ, Ogle K, Lin LY, Bialer M, Finnell RH. Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice. Bipolar Disord. 2015 Sep; 17(6):615-25. PMID: 26292082; PMCID: PMC4631615.
      Citations: 7     Fields:    Translation:Animals
    130. Shawlot W, Vazquez-Chantada M, Wallingford JB, Finnell RH. Rfx2 is required for spermatogenesis in the mouse. Genesis. 2015 Sep; 53(9):604-611. PMID: 26248850; PMCID: PMC4744581.
      Citations: 4     Fields:    
    131. Wang B, Jin L, Ren A, Yuan Y, Liu J, Li Z, Zhang L, Yi D, Wang LL, Zhang Y, Wang X, Tao S, Finnell RH. Correction to Levels of Polycyclic Aromatic Hydrocarbons in Maternal Serum and Risk of Neural Tube Defects in Offspring. Environ Sci Technol. 2015 Sep 01; 49(17):10754-5. PMID: 26274604; PMCID: PMC5104405.
      Citations: 1     Fields:    
    132. Cantarel BL, Lei Y, Weaver D, Zhu H, Farrell A, Benstead-Hume G, Reese J, Finnell RH. Analysis of archived residual newborn screening blood spots after whole genome amplification. BMC Genomics. 2015 Aug 13; 16:602. PMID: 26268606; PMCID: PMC4535253.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    133. Webber DM, MacLeod SL, Bamshad MJ, Shaw GM, Finnell RH, Shete SS, Witte JS, Erickson SW, Murphy LD, Hobbs C. Developments in our understanding of the genetic basis of birth defects. Birth Defects Res A Clin Mol Teratol. 2015 Aug; 103(8):680-91. PMID: 26033863; PMCID: PMC4537658.
      Citations: 11     Fields:    Translation:Humans
    134. Mawasi H, Shekh-Ahmad T, Finnell RH, Wlodarczyk BJ, Bialer M. Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid. Epilepsy Behav. 2015 May; 46:72-8. PMID: 25863940.
      Citations: 5     Fields:    Translation:AnimalsCells
    135. Lei Y, Fathe K, McCartney D, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH. Rare LRP6 variants identified in spina bifida patients. Hum Mutat. 2015 Mar; 36(3):342-9. PMID: 25546815; PMCID: PMC4361299.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    136. Wang B, Jin L, Ren A, Yuan Y, Liu J, Li Z, Zhang L, Yi D, Wang LL, Zhang Y, Wang X, Tao S, Finnell RH. Levels of polycyclic aromatic hydrocarbons in maternal serum and risk of neural tube defects in offspring. Environ Sci Technol. 2015 Jan 06; 49(1):588-96. PMID: 25488567; PMCID: PMC4291766.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    137. Yi D, Yuan Y, Jin L, Zhou G, Zhu H, Finnell RH, Ren A. Levels of PAH-DNA adducts in cord blood and cord tissue and the risk of fetal neural tube defects in a Chinese population. Neurotoxicology. 2015 Jan; 46:73-8. PMID: 25522656; PMCID: PMC4339482.
      Citations: 9     Fields:    Translation:Humans
    138. Shekh-Ahmad T, Mawasi H, McDonough JH, Finnell RH, Wlodarczyk BJ, Yavin E, Bialer M. Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid. Epilepsia. 2014 Dec; 55(12):1944-52. PMID: 25442425.
      Citations: 2     Fields:    Translation:Animals
    139. Fathe K, Person MD, Finnell RH. The application of a chemical determination of N-homocysteinylation levels in developing mouse embryos: implication for folate responsive birth defects. J Nutr Biochem. 2015 Apr; 26(4):312-8. PMID: 25620692; PMCID: PMC4375028.
      Citations: 2     Fields:    Translation:Animals
    140. Mestre D, Fresnedo O, Martin-Guerrero I, Luka Z, Wagner C, Lu SC, Finnell RH, Aurrekoetxea I, Aspichueta P, Mart?nez-U?a M, Varela-Rey M, Fern?ndez-Ares L, Fernandez-Ramos D, Guti?rrez-de Juan V, Garc?a-Orad A, Garc?a-Monz?n C, Buqu? X, Mart?nez-Chantar ML, Mato JM. S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease. J Hepatol. 2015 Mar; 62(3):673-81. PMID: 25457203; PMCID: PMC4336596.
      Citations: 22     Fields:    Translation:HumansAnimals
    141. Hansler A, Chen Q, Gray JD, Ross ME, Finnell RH, Gross SS. Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects. Birth Defects Res A Clin Mol Teratol. 2014 Aug; 100(8):623-32. PMID: 25115437; PMCID: PMC4146720.
      Citations: 6     Fields:    Translation:AnimalsCells
    142. Mitchell LE, Finnell RH. Papers from the Eighth International Neural Tube Defects Conference. Birth Defects Res A Clin Mol Teratol. 2014 Aug; 100(8):561-2. PMID: 25155952.
      Citations:    Fields:    Translation:HumansAnimals
    143. Fathe K, Palacios A, Finnell RH. Brief report novel mechanism for valproate-induced teratogenicity. Birth Defects Res A Clin Mol Teratol. 2014 Aug; 100(8):592-7. PMID: 25066307; PMCID: PMC4396868.
      Citations: 12     Fields:    Translation:HumansCells
    144. Tsurubuchi T, Allender EV, Siddiqui MR, Shim KW, Ichi S, Boshnjaku V, Mania-Farnell B, Xi G, Finnell RH, McLone DG, Tomita T, Mayanil CS. A critical role of noggin in developing folate-nonresponsive NTD in Fkbp8 -/- embryos. Childs Nerv Syst. 2014 Aug; 30(8):1343-53. PMID: 24817375.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    145. Lei Y, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH. Identification of novel CELSR1 mutations in spina bifida. PLoS One. 2014; 9(3):e92207. PMID: 24632739; PMCID: PMC3954890.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    146. Wlodarczyk BJ, Zhu H, Finnell RH. Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity. Toxicol Appl Pharmacol. 2014 Feb 15; 275(1):22-7. PMID: 24384392; PMCID: PMC3943866.
      Citations: 6     Fields:    Translation:AnimalsPHPublic Health
    147. Shekh-Ahmad T, Hen N, Yagen B, McDonough JH, Finnell RH, Wlodarczyk BJ, Bialer M. Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential. Epilepsia. 2014 Feb; 55(2):353-61. PMID: 24313671; PMCID: PMC4963464.
      Citations: 10     Fields:    Translation:Animals
    148. Lupo PJ, Mitchell LE, Canfield MA, Shaw GM, Olshan AF, Finnell RH, Zhu H, National Birth Defects Prevention Study. Maternal-fetal metabolic gene-gene interactions and risk of neural tube defects. Mol Genet Metab. 2014 Jan; 111(1):46-51. PMID: 24332798; PMCID: PMC4394735.
      Citations: 18     Fields:    Translation:Humans
    149. Denny KJ, Jeanes A, Fathe K, Finnell RH, Taylor SM, Woodruff TM. Neural tube defects, folate, and immune modulation. Birth Defects Res A Clin Mol Teratol. 2013 Sep; 97(9):602-609. PMID: 24078477; PMCID: PMC4053177.
      Citations: 10     Fields:    Translation:Humans
    150. Varela-Rey M, Cano A, Beraza N, Aurrekoetxea I, Mestre D, Luka Z, Wagner C, Alonso C, Finnell RH, Lu SC, Aspichueta P, Mart?nez-U?a M, Fern?ndez-Ares L, Mart?nez-Arranz I, Garc?a-Rodr?guez JL, Buqu? X, Mart?nez-Chantar ML, Mato JM. Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis. Hepatology. 2013 Oct; 58(4):1296-305. PMID: 23505042; PMCID: PMC3720726.
      Citations: 43     Fields:    Translation:Animals
    151. Hen N, Shekh-Ahmad T, Yagen B, McDonough JH, Finnell RH, Wlodarczyk B, Bialer M. Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus. J Med Chem. 2013 Aug 22; 56(16):6467-77. PMID: 23879329.
      Citations: 7     Fields:    Translation:Animals
    152. Agopian AJ, Bhalla AD, Boerwinkle E, Finnell RH, Grove ML, Hixson JE, Shimmin LC, Sewda A, Stuart C, Zhong Y, Zhu H, Mitchell LE. Exon sequencing of PAX3 and T (brachyury) in cases with spina bifida. Birth Defects Res A Clin Mol Teratol. 2013 Sep; 97(9):597-601. PMID: 23913553; PMCID: PMC3877942.
      Citations: 6     Fields:    Translation:HumansCells
    153. Lei Y, Zhu H, Duhon C, Yang W, Ross ME, Shaw GM, Finnell RH. Mutations in planar cell polarity gene SCRIB are associated with spina bifida. PLoS One. 2013; 8(7):e69262. PMID: 23922697; PMCID: PMC3724847.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    154. Tabler JM, Barrell WB, Szabo-Rogers HL, Healy C, Yeung Y, Perdiguero EG, Schulz C, Yannakoudakis BZ, Mesbahi A, Wlodarczyk B, Geissmann F, Finnell RH, Wallingford JB, Liu KJ. Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes. Dev Cell. 2013 Jun 24; 25(6):623-35. PMID: 23806618; PMCID: PMC3697100.
      Citations: 39     Fields:    Translation:Animals
    155. Wallingford JB, Niswander LA, Shaw GM, Finnell RH. The continuing challenge of understanding, preventing, and treating neural tube defects. Science. 2013 Mar 01; 339(6123):1222002. PMID: 23449594; PMCID: PMC3677196.
      Citations: 176     Fields:    Translation:HumansAnimalsPHPublic Health
    156. Lai SC, Nakayama Y, Sequeira JM, Wlodarczyk BJ, Cabrera RM, Finnell RH, Bottiglieri T, Quadros EV. The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system. FASEB J. 2013 Jun; 27(6):2468-75. PMID: 23430977; PMCID: PMC3659357.
      Citations: 14     Fields:    Translation:HumansAnimals
    157. Denny KJ, Coulthard LG, Jeanes A, Lisgo S, Simmons DG, Callaway LK, Wlodarczyk B, Finnell RH, Woodruff TM, Taylor SM. C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice. J Immunol. 2013 Apr 01; 190(7):3493-9. PMID: 23420882; PMCID: PMC3608813.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    158. Yuan Y, Jin L, Wang L, Li Z, Zhang L, Zhu H, Finnell RH, Zhou G, Ren A. Levels of PAH-DNA adducts in placental tissue and the risk of fetal neural tube defects in a Chinese population. Reprod Toxicol. 2013 Jun; 37:70-5. PMID: 23416326; PMCID: PMC4040017.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    159. Isaksson HS, Finnell RH, Ren A, Farkas SA, B?ttiger AK, Nilsson TK. Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia. Epigenetics. 2013 Mar; 8(3):303-16. PMID: 23417011; PMCID: PMC3669122.
      Citations: 15     Fields:    Translation:HumansCells
    160. Denny KJ, Coulthard LG, Finnell RH, Callaway LK, Taylor SM, Woodruff TM. Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia. J Reprod Immunol. 2013 Apr; 97(2):211-6. PMID: 23415845.
      Citations: 18     Fields:    Translation:Humans
    161. Wang X, Cabrera RM, Li Y, Miller DS, Finnell RH. Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice. FASEB J. 2013 Mar; 27(3):1167-75. PMID: 23212123; PMCID: PMC3574287.
      Citations: 10     Fields:    Translation:AnimalsCells
    162. Lupo PJ, Canfield MA, Chapa C, Lu W, Agopian AJ, Mitchell LE, Shaw GM, Waller DK, Olshan AF, Finnell RH, Zhu H. Diabetes and obesity-related genes and the risk of neural tube defects in the national birth defects prevention study. Am J Epidemiol. 2012 Dec 15; 176(12):1101-9. PMID: 23132673; PMCID: PMC3571234.
      Citations: 23     Fields:    Translation:Humans
    163. Wlodarczyk B, Spiegelstein O, Hill D, Le XC, Finnell RH. Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate. Toxicol Lett. 2012 Dec 17; 215(3):214-8. PMID: 23123153.
      Citations: 4     Fields:    Translation:Animals
    164. Cabrera RM, Finnell RH, Zhu H, Shaw GM, Wlodarczyk BJ. Transcriptional analyses of two mouse models of spina bifida. Birth Defects Res A Clin Mol Teratol. 2012 Oct; 94(10):782-9. PMID: 23024056; PMCID: PMC3505988.
      Citations:    Fields:    Translation:HumansAnimalsCells
    165. Lupo PJ, Chapa C, Nousome D, Duhon C, Canfield MA, Shaw GM, Finnell RH, Zhu H, National Birth Defects Prevention Study. A GCH1 haplotype and risk of neural tube defects in the National Birth Defects Prevention Study. Mol Genet Metab. 2012 Nov; 107(3):592-5. PMID: 23059057; PMCID: PMC3704723.
      Citations: 5     Fields:    Translation:Humans
    166. Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, Hansen J, Hicks G, Houghton R, Huylebroeck D, Iyer V, de Jong PJ, Kadin JA, Kaloff C, Kennedy K, Koutsourakis M, Lloyd KC, Marschall S, Mason J, McKerlie C, McLeod MP, von Melchner H, Moore M, Mujica AO, Nagy A, Nefedov M, Nutter LM, Pavlovic G, Peterson JL, Pollock J, Ramirez-Solis R, Rancourt DE, Raspa M, Remacle JE, Ringwald M, Rosen B, Rosenthal N, Rossant J, Ruiz Noppinger P, Ryder E, Schick JZ, Schofield P, Seisenberger C, Selloum M, Simpson EM, Skarnes WC, Smedley D, Stanford WL, Stewart AF, Stone K, Swan K, Tadepally H, Teboul L, Tocchini-Valentini GP, Valenzuela D, West AP, Yamamura K, Yoshinaga Y, Wurst W, B?rger A, H?rault Y, H?rlein A, Hrab? de Angelis M, Schn?tgen F. The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome. 2012 Oct; 23(9-10):580-6. PMID: 22968824; PMCID: PMC3463800.
      Citations: 168     Fields:    Translation:Animals
    167. Etheredge AJ, Finnell RH, Carmichael SL, Lammer EJ, Zhu H, Mitchell LE, Shaw GM. Maternal and infant gene-folate interactions and the risk of neural tube defects. Am J Med Genet A. 2012 Oct; 158A(10):2439-46. PMID: 22903727; PMCID: PMC3448841.
      Citations: 23     Fields:    Translation:Humans
    168. Zhu H, Yang W, Shaw N, Perloff S, Carmichael SL, Finnell RH, Shaw GM, Lammer EJ. Thymidylate synthase polymorphisms and risk of conotruncal heart defects. Am J Med Genet A. 2012 Sep; 158A(9):2194-203. PMID: 22887475; PMCID: PMC3429723.
      Citations: 6     Fields:    Translation:HumansCells
    169. Wlodarczyk BJ, Palacios AM, George TM, Finnell RH. Antiepileptic drugs and pregnancy outcomes. Am J Med Genet A. 2012 Aug; 158A(8):2071-90. PMID: 22711424; PMCID: PMC3402584.
      Citations: 25     Fields:    Translation:Humans
    170. Wallis D, Hill DS, Mendez IA, Abbott LC, Finnell RH, Wellman PJ, Setlow B. Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction. Brain Res. 2012 Jun 29; 1463:85-92. PMID: 22575564.
      Citations: 37     Fields:    Translation:AnimalsCells
    171. Zhu H, Yang W, Lu W, Etheredge AJ, Lammer EJ, Finnell RH, Carmichael SL, Shaw GM. Gene variants in the folate-mediated one-carbon metabolism (FOCM) pathway as risk factors for conotruncal heart defects. Am J Med Genet A. 2012 May; 158A(5):1124-34. PMID: 22495907; PMCID: PMC3331895.
      Citations: 10     Fields:    Translation:Humans
    172. Lin SC, Wong RL, Finnell RH, Niederreither K, Paschaki M, Doll? P. Retinoic acid-dependent signaling pathways and lineage events in the developing mouse spinal cord. PLoS One. 2012; 7(3):e32447. PMID: 22396766; PMCID: PMC3292566.
      Citations: 9     Fields:    Translation:AnimalsCells
    173. Lupo PJ, Langlois PH, Reefhuis J, Lawson CC, Symanski E, Desrosiers TA, Khodr ZG, Agopian AJ, Waters MA, Duwe KN, Finnell RH, Mitchell LE, Moore CA, Romitti PA, Shaw GM, National Birth Defects Prevention Study. Maternal occupational exposure to polycyclic aromatic hydrocarbons: effects on gastroschisis among offspring in the National Birth Defects Prevention Study. Environ Health Perspect. 2012 Jun; 120(6):910-5. PMID: 22330681; PMCID: PMC3385431.
      Citations: 31     Fields:    Translation:HumansPHPublic Health
    174. Psychoyos D, Vinod KY, Cao J, Xie S, Hyson RL, Wlodarczyk B, He W, Cooper TB, Hungund BL, Finnell RH. Cannabinoid receptor 1 signaling in embryo neurodevelopment. Birth Defects Res B Dev Reprod Toxicol. 2012 Apr; 95(2):137-50. PMID: 22311661; PMCID: PMC4175447.
      Citations: 19     Fields:    Translation:AnimalsCells
    175. Pessah N, Yagen B, Hen N, Shimshoni JA, Wlodarczyk B, Finnell RH, Bialer M. Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid. Epilepsy Behav. 2011 Nov; 22(3):461-8. PMID: 21959082.
      Citations: 2     Fields:    Translation:AnimalsCells
    176. Zhang Z, Wlodarczyk BJ, Niederreither K, Venugopalan S, Florez S, Finnell RH, Amendt BA. Fuz regulates craniofacial development through tissue specific responses to signaling factors. PLoS One. 2011; 6(9):e24608. PMID: 21935430; PMCID: PMC3173472.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    177. Ren A, Qiu X, Jin L, Ma J, Li Z, Zhang L, Zhu H, Finnell RH, Zhu T. Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects. Proc Natl Acad Sci U S A. 2011 Aug 02; 108(31):12770-5. PMID: 21768370; PMCID: PMC3150927.
      Citations: 69     Fields:    Translation:HumansPHPublic Health
    178. Wlodarczyk BJ, Palacios AM, Chapa CJ, Zhu H, George TM, Finnell RH. Genetic basis of susceptibility to teratogen induced birth defects. Am J Med Genet C Semin Med Genet. 2011 Aug 15; 157C(3):215-26. PMID: 21766441.
      Citations: 11     Fields:    Translation:HumansPHPublic Health
    179. Boyles AL, Ballard JL, Gorman EB, McConnaughey DR, Cabrera RM, Wilcox AJ, Lie RT, Finnell RH. Association between inhibited binding of folic acid to folate receptor alpha in maternal serum and folate-related birth defects in Norway. Hum Reprod. 2011 Aug; 26(8):2232-8. PMID: 21576080; PMCID: PMC3137385.
      Citations: 13     Fields:    Translation:Humans
    180. Wang J, Chen L, Wen S, Zhu H, Yu W, Moskowitz IP, Shaw GM, Finnell RH, Schwartz RJ. Defective sumoylation pathway directs congenital heart disease. Birth Defects Res A Clin Mol Teratol. 2011 Jun; 91(6):468-76. PMID: 21563299; PMCID: PMC5031480.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    181. Salojin KV, Cabrera RM, Sun W, Chang WC, Lin C, Duncan L, Platt KA, Read R, Vogel P, Liu Q, Finnell RH, Oravecz T. A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency. Blood. 2011 May 05; 117(18):4895-904. PMID: 21346251.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    182. Blanton SH, Henry RR, Yuan Q, Mulliken JB, Stal S, Finnell RH, Hecht JT. Folate pathway and nonsyndromic cleft lip and palate. Birth Defects Res A Clin Mol Teratol. 2011 Jan; 91(1):50-60. PMID: 21254359; PMCID: PMC4098909.
      Citations: 27     Fields:    Translation:Humans
    183. Dai D, Zhu H, Wlodarczyk B, Zhang L, Li L, Li AG, Finnell RH, Roop DR, Chen J. Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. J Invest Dermatol. 2011 Feb; 131(2):302-10. PMID: 20962855.
      Citations: 27     Fields:    Translation:AnimalsCells
    184. Lu W, Guzman AR, Yang W, Chapa CJ, Shaw GM, Greene RM, Pisano MM, Lammer EJ, Finnell RH, Zhu H. Genes encoding critical transcriptional activators for murine neural tube development and human spina bifida: a case-control study. BMC Med Genet. 2010 Oct 08; 11:141. PMID: 20932315; PMCID: PMC2964532.
      Citations: 7     Fields:    Translation:HumansAnimals
    185. Pessah N, Kaufmann D, Yagen B, Hen N, Wlodarczyk B, Finnell RH, Bialer M. Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid. Epilepsia. 2010 Oct; 51(10):1944-53. PMID: 20738383.
      Citations: 3     Fields:    Translation:HumansAnimals
    186. Obican SG, Finnell RH, Mills JL, Shaw GM, Scialli AR. Folic acid in early pregnancy: a public health success story. FASEB J. 2010 Nov; 24(11):4167-74. PMID: 20631328; PMCID: PMC2974421.
      Citations: 36     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    187. Hill DS, Wlodarczyk BJ, Palacios AM, Finnell RH. Teratogenic effects of antiepileptic drugs. Expert Rev Neurother. 2010 Jun; 10(6):943-59. PMID: 20518610; PMCID: PMC2970517.
      Citations: 33     Fields:    Translation:Humans
    188. Hen N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B. Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide. J Med Chem. 2010 May 27; 53(10):4177-86. PMID: 20420384.
      Citations: 4     Fields:    Translation:Animals
    189. Iskandar BJ, Rizk E, Meier B, Hariharan N, Bottiglieri T, Finnell RH, Jarrard DF, Banerjee RV, Skene JH, Nelson A, Patel N, Gherasim C, Simon K, Cook TD, Hogan KJ. Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. J Clin Invest. 2010 May; 120(5):1603-16. PMID: 20424322; PMCID: PMC2860927.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    190. Finnell RH, Blom HJ, Shaw GM. Does global hypomethylation contribute to susceptibility to neural tube defects? Am J Clin Nutr. 2010 May; 91(5):1153-4. PMID: 20375188; PMCID: PMC2854894.
      Citations: 1     Fields:    Translation:HumansCells
    191. Rosenquist TH, Chaudoin T, Finnell RH, Bennett GD. High-affinity folate receptor in cardiac neural crest migration: a gene knockdown model using siRNA. Dev Dyn. 2010 Apr; 239(4):1136-44. PMID: 20235221.
      Citations: 6     Fields:    Translation:Animals
    192. Kaufmann D, Yagen B, Minert A, Wlodarczyk B, Finnell RH, Schurig V, Devor M, Bialer M. Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid. Neuropharmacology. 2010 Jun; 58(8):1228-36. PMID: 20230843.
      Citations: 10     Fields:    Translation:Animals
    193. Bille C, Pedersen DA, Andersen AM, Mansilla MA, Murray JC, Christensen K, Ballard JL, Gorman EB, Cabrera RM, Finnell RH. Autoantibodies to folate receptor alpha during early pregnancy and risk of oral clefts in Denmark. Pediatr Res. 2010 Mar; 67(3):274-9. PMID: 19952865; PMCID: PMC2909840.
      Citations: 8     Fields:    Translation:Humans
    194. Wen S, Zhu H, Lu W, Mitchell LE, Shaw GM, Lammer EJ, Finnell RH. Planar cell polarity pathway genes and risk for spina bifida. Am J Med Genet A. 2010 Feb; 152A(2):299-304. PMID: 20101694; PMCID: PMC2815123.
      Citations: 15     Fields:    Translation:HumansAnimals
    195. Embade N, Varela-Rey M, Woodhoo A, Luka Z, Wagner C, Anglim PP, Finnell RH, Laird-Offringa IA, Gorospe M, Lu SC, V?zquez-Chantada M, Fern?ndez-Ramos D, Mart?nez-Lopez N, Caballer?a J, Mato JM, Mart?nez-Chantar ML. HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis. Gastroenterology. 2010 May; 138(5):1943-53. PMID: 20102719; PMCID: PMC2860011.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    196. Pisano MM, Bhattacherjee V, Wong L, Finnell RH, Greene RM. Novel folate binding protein-1 interactions in embryonic orofacial tissue. Life Sci. 2010 Feb 13; 86(7-8):275-80. PMID: 20045418; PMCID: PMC2819649.
      Citations:    Fields:    Translation:AnimalsCells
    197. Shaw GM, Vollset SE, Carmichael SL, Yang W, Finnell RH, Blom H, Ueland PM. Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate. Pediatr Res. 2009 Nov; 66(5):501-6. PMID: 19668105; PMCID: PMC3095388.
      Citations: 7     Fields:    Translation:Humans
    198. Gray RS, Abitua PB, Wlodarczyk BJ, Szabo-Rogers HL, Blanchard O, Lee I, Weiss GS, Liu KJ, Marcotte EM, Wallingford JB, Finnell RH. The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol. 2009 Oct; 11(10):1225-32. PMID: 19767740; PMCID: PMC2755648.
      Citations: 114     Fields:    Translation:AnimalsCells
    199. Shaw GM, Finnell RH, Blom HJ, Carmichael SL, Vollset SE, Yang W, Ueland PM. Choline and risk of neural tube defects in a folate-fortified population. Epidemiology. 2009 Sep; 20(5):714-9. PMID: 19593156.
      Citations: 59     Fields:    Translation:Humans
    200. Shimshoni JA, Yagen B, Wlodarczyk B, Finnell RH, Schurig V, Bialer M. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative. Epilepsia. 2010 Mar; 51(3):323-32. PMID: 19674061.
      Citations: 2     Fields:    Translation:Animals
    201. Hardin J, Finnell RH, Wong D, Hogan ME, Horovitz J, Shu J, Shaw GM. Whole genome microarray analysis, from neonatal blood cards. BMC Genet. 2009 Jul 22; 10:38. PMID: 19624846; PMCID: PMC2722673.
      Citations: 12     Fields:    Translation:Humans
    202. Kibar Z, Bosoi CM, Kooistra M, Salem S, Finnell RH, De Marco P, Merello E, Bassuk AG, Capra V, Gros P. Novel mutations in VANGL1 in neural tube defects. Hum Mutat. 2009 Jul; 30(7):E706-15. PMID: 19319979; PMCID: PMC2885434.
      Citations: 55     Fields:    Translation:Humans
    203. Shaw GM, Lu W, Zhu H, Yang W, Briggs FB, Carmichael SL, Barcellos LF, Lammer EJ, Finnell RH. 118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects. BMC Med Genet. 2009 Jun 03; 10:49. PMID: 19493349; PMCID: PMC2700092.
      Citations: 87     Fields:    Translation:Humans
    204. Shi Z, Cai Z, Wen S, Chen C, Gendron C, Sanchez A, Patterson K, Fu S, Yang J, Wildman D, Finnell RH, Zhang D. Transcriptional regulation of the novel Toll-like receptor Tlr13. J Biol Chem. 2009 Jul 31; 284(31):20540-7. PMID: 19487701; PMCID: PMC2742818.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    205. Hill DS, Wlodarczyk BJ, Mitchell LE, Finnell RH. Arsenate-induced maternal glucose intolerance and neural tube defects in a mouse model. Toxicol Appl Pharmacol. 2009 Aug 15; 239(1):29-36. PMID: 19446573; PMCID: PMC3998373.
      Citations: 22     Fields:    Translation:AnimalsPHPublic Health
    206. Zhu H, Kartiko S, Finnell RH. Importance of gene-environment interactions in the etiology of selected birth defects. Clin Genet. 2009 May; 75(5):409-23. PMID: 19459879.
      Citations: 45     Fields:    Translation:HumansAnimalsPHPublic Health
    207. Harden CL, Hopp J, Ting TY, Pennell PB, French JA, Allen Hauser W, Wiebe S, Gronseth GS, Thurman D, Meador KJ, Koppel BS, Kaplan PW, Robinson JN, Gidal B, Hovinga CA, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Le Guen C, American Academy of Neurology, American Epilepsy Society. Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): I. Obstetrical complications and change in seizure frequency: Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Epilepsia. 2009 May; 50(5):1229-36. PMID: 19496807.
      Citations: 25     Fields:    Translation:Humans
    208. Harden CL, Meador KJ, Pennell PB, Hauser WA, Gronseth GS, French JA, Wiebe S, Thurman D, Koppel BS, Kaplan PW, Robinson JN, Hopp J, Ting TY, Gidal B, Hovinga CA, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Hirtz D, Le Guen C, American Academy of Neurology, American Epilepsy Society. Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes: Report of the Quality Standards Subcommittee and Therapeutics and Technology Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Epilepsia. 2009 May; 50(5):1237-46. PMID: 19507301.
      Citations: 60     Fields:    Translation:Humans
    209. Harden CL, Pennell PB, Koppel BS, Hovinga CA, Gidal B, Meador KJ, Hopp J, Ting TY, Hauser WA, Thurman D, Kaplan PW, Robinson JN, French JA, Wiebe S, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Shafer PO, Le Guen CL, American Academy of Neurology, American Epilepsy Society. Management issues for women with epilepsy--focus on pregnancy (an evidence-based review): III. Vitamin K, folic acid, blood levels, and breast-feeding: Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Epilepsia. 2009 May; 50(5):1247-55. PMID: 19507305.
      Citations: 34     Fields:    Translation:Humans
    210. Harden CL, Pennell PB, Koppel BS, Hovinga CA, Gidal B, Meador KJ, Hopp J, Ting TY, Hauser WA, Thurman D, Kaplan PW, Robinson JN, French JA, Wiebe S, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Shafer PO, Le Guen C, American Academy of Neurology, American Epilepsy Society. Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society. Neurology. 2009 Jul 14; 73(2):142-9. PMID: 19398680; PMCID: PMC3475193.
      Citations: 60     Fields:    Translation:Humans
    211. Harden CL, Meador KJ, Pennell PB, Hauser WA, Gronseth GS, French JA, Wiebe S, Thurman D, Koppel BS, Kaplan PW, Robinson JN, Hopp J, Ting TY, Gidal B, Hovinga CA, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Hirtz D, Le Guen C, American Academy of Neurology, American Epilepsy Society. Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): teratogenesis and perinatal outcomes: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society. Neurology. 2009 Jul 14; 73(2):133-41. PMID: 19398681; PMCID: PMC3475194.
      Citations: 73     Fields:    Translation:Humans
    212. Harden CL, Hopp J, Ting TY, Pennell PB, French JA, Hauser WA, Wiebe S, Gronseth GS, Thurman D, Meador KJ, Koppel BS, Kaplan PW, Robinson JN, Gidal B, Hovinga CA, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Le Guen C, American Academy of Neurology, American Epilepsy Society. Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): obstetrical complications and change in seizure frequency: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society. Neurology. 2009 Jul 14; 73(2):126-32. PMID: 19398682; PMCID: PMC3475195.
      Citations: 53     Fields:    Translation:Humans
    213. Pessah N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B. Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid. J Med Chem. 2009 Apr 23; 52(8):2233-42. PMID: 19296679.
      Citations: 7     Fields:    Translation:Animals
    214. Salbaum JM, Finnell RH, Kappen C. Regulation of folate receptor 1 gene expression in the visceral endoderm. Birth Defects Res A Clin Mol Teratol. 2009 Apr; 85(4):303-13. PMID: 19180647; PMCID: PMC2731486.
      Citations: 9     Fields:    Translation:AnimalsCells
    215. Naufal Z, Zhiwen L, Zhu L, Zhou GD, McDonald T, He LY, Mitchell L, Ren A, Zhu H, Finnell R, Donnelly KC. Biomarkers of exposure to combustion by-products in a human population in Shanxi, China. J Expo Sci Environ Epidemiol. 2010 Jun; 20(4):310-9. PMID: 19277067.
      Citations: 16     Fields:    Translation:HumansPHPublic Health
    216. Psychoyos D, Finnell R. Assay for neural induction in the chick embryo. J Vis Exp. 2009 Feb 13; (24). PMID: 19229186; PMCID: PMC2762894.
      Citations: 1     Fields:    Translation:Animals
    217. Jakubowski H, Finnell RH, Cabrera RM, Wang H, Gupta S, Kruger WD, Kraus JP, Shih DM, Perla-Kaj?n J. Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice. FASEB J. 2009 Jun; 23(6):1721-7. PMID: 19204075; PMCID: PMC3221610.
      Citations: 33     Fields:    Translation:HumansAnimals
    218. Psychoyos D, Finnell R. Method for whole mount antibody staining in chick. J Vis Exp. 2009 Feb 02; (24). PMID: 19488030; PMCID: PMC2783013.
      Citations: 1     Fields:    Translation:Animals
    219. Wen S, Lu W, Zhu H, Yang W, Shaw GM, Lammer EJ, Islam A, Finnell RH. Genetic polymorphisms in the thioredoxin 2 (TXN2) gene and risk for spina bifida. Am J Med Genet A. 2009 Feb; 149A(2):155-60. PMID: 19165900; PMCID: PMC2970524.
      Citations: 5     Fields:    Translation:HumansCells
    220. Shaw GM, Carmichael SL, Vollset SE, Yang W, Finnell RH, Blom H, Ueland PM, Midttun ?. Mid-pregnancy cotinine and risks of orofacial clefts and neural tube defects. J Pediatr. 2009 Jan; 154(1):17-9. PMID: 18990410.
      Citations: 19     Fields:    Translation:Humans
    221. Psychoyos D, Finnell R. Double whole mount in situ hybridization of early chick embryos. J Vis Exp. 2008 Oct 27; (20). PMID: 19078944; PMCID: PMC3148599.
      Citations: 2     Fields:    Translation:Animals
    222. Psychoyos D, Finnell R. Method for Culture of Early Chick Embryos ex vivo (New Culture). J Vis Exp. 2008 Oct 20; (20). PMID: 19078945; PMCID: PMC3234035.
      Citations: 3     Fields:    Translation:Animals
    223. Chapkin RS, Kamen BA, Callaway ES, Davidson LA, George NI, Wang N, Lupton JR, Finnell RH. Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer. J Nutr Biochem. 2009 Aug; 20(8):649-55. PMID: 18926688; PMCID: PMC2710403.
      Citations: 9     Fields:    Translation:Animals
    224. Psychoyos D, Hungund B, Cooper T, Finnell RH. A cannabinoid analogue of Delta9-tetrahydrocannabinol disrupts neural development in chick. Birth Defects Res B Dev Reprod Toxicol. 2008 Oct; 83(5):477-88. PMID: 19040278.
      Citations: 13     Fields:    Translation:Animals
    225. Lu W, Zhu H, Wen S, Yang W, Shaw GM, Lammer EJ, Finnell RH. Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida. Birth Defects Res A Clin Mol Teratol. 2008 Oct; 82(10):670-5. PMID: 18553462; PMCID: PMC2630518.
      Citations: 2     Fields:    Translation:Humans
    226. Cabrera RM, Shaw GM, Ballard JL, Carmichael SL, Yang W, Lammer EJ, Finnell RH. Autoantibodies to folate receptor during pregnancy and neural tube defect risk. J Reprod Immunol. 2008 Oct; 79(1):85-92. PMID: 18804286; PMCID: PMC3998370.
      Citations: 23     Fields:    Translation:Humans
    227. Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct; 18(10):1670-9. PMID: 18799693; PMCID: PMC2556270.
      Citations: 65     Fields:    Translation:AnimalsCells
    228. Chapin R, Augustine-Rauch K, Beyer B, Daston G, Finnell R, Flynn T, Hunter S, Mirkes P, O'Shea KS, Piersma A, Sandler D, Vanparys P, Van Maele-Fabry G. State of the art in developmental toxicity screening methods and a way forward: a meeting report addressing embryonic stem cells, whole embryo culture, and zebrafish. Birth Defects Res B Dev Reprod Toxicol. 2008 Aug; 83(4):446-56. PMID: 18702117.
      Citations: 6     Fields:    Translation:AnimalsCells
    229. Shimshoni JA, Yagen B, Pessah N, Wlodarczyk B, Finnell RH, Bialer M. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid. Epilepsia. 2008 Jul; 49(7):1202-12. PMID: 18435754.
      Citations: 4     Fields:    Translation:Animals
    230. Gelineau-van Waes J, Heller S, Bauer LK, Wilberding J, Maddox JR, Aleman F, Rosenquist TH, Finnell RH. Embryonic development in the reduced folate carrier knockout mouse is modulated by maternal folate supplementation. Birth Defects Res A Clin Mol Teratol. 2008 Jul; 82(7):494-507. PMID: 18383508.
      Citations: 28     Fields:    Translation:Animals
    231. Finnell RH, Shaw GM, Lammer EJ, Rosenquist TH. Gene-nutrient interactions: importance of folic acid and vitamin B12 during early embryogenesis. Food Nutr Bull. 2008 Jun; 29(2 Suppl):S86-98; discussion S99-100. PMID: 18709884.
      Citations: 6     Fields:    Translation:Humans
    232. Gelineau-van Waes J, Maddox JR, Smith LM, van Waes M, Wilberding J, Eudy JD, Bauer LK, Finnell RH. Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. BMC Genomics. 2008 Apr 09; 9:156. PMID: 18400109; PMCID: PMC2383917.
      Citations: 10     Fields:    Translation:Animals
    233. Hill DS, Wlodarczyk BJ, Finnell RH. Reproductive consequences of oral arsenate exposure during pregnancy in a mouse model. Birth Defects Res B Dev Reprod Toxicol. 2008 Feb; 83(1):40-7. PMID: 18186108.
      Citations: 22     Fields:    Translation:AnimalsPHPublic Health
    234. Kappen C, Balling R, Finnell R, Neub?ser A. Molecular basis for skeletal variation: insights from developmental genetic studies in mice. Birth Defects Res B Dev Reprod Toxicol. 2007 Dec; 80(6):425-50. PMID: 18157899; PMCID: PMC3938168.
      Citations: 3     Fields:    Translation:Animals
    235. Zhu H, Cabrera RM, Wlodarczyk BJ, Bozinov D, Wang D, Schwartz RJ, Finnell RH. Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity. BMC Dev Biol. 2007 Nov 20; 7:128. PMID: 18028541; PMCID: PMC2206038.
      Citations: 17     Fields:    Translation:Animals
    236. Wong RL, Wlodarczyk BJ, Min KS, Scott ML, Kartiko S, Yu W, Merriweather MY, Vogel P, Zambrowicz BP, Finnell RH. Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube. Hum Mol Genet. 2008 Feb 15; 17(4):587-601. PMID: 18003640.
      Citations: 19     Fields:    Translation:HumansAnimals
    237. Shimshoni JA, Bialer M, Wlodarczyk B, Finnell RH, Yagen B. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. J Med Chem. 2007 Dec 13; 50(25):6419-27. PMID: 17994680.
      Citations: 7     Fields:    Translation:Animals
    238. Shaw GM, Carmichael SL, Laurent C, Louik C, Finnell RH, Lammer EJ, National Birth Defects Prevention Study. Nutrient intakes in women and risks of anophthalmia and microphthalmia in their offspring. Birth Defects Res A Clin Mol Teratol. 2007 Oct; 79(10):708-13. PMID: 17847120.
      Citations: 6     Fields:    Translation:Humans
    239. Ramirez D, Lammer EJ, Iovannisci DM, Laurent C, Finnell RH, Shaw GM. Maternal smoking during early pregnancy, GSTP1 and EPHX1 variants, and risk of isolated orofacial clefts. Cleft Palate Craniofac J. 2007 Jul; 44(4):366-73. PMID: 17608547.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    240. Collins FS, Finnell RH, Rossant J, Wurst W. A new partner for the international knockout mouse consortium. Cell. 2007 Apr 20; 129(2):235. PMID: 17448981.
      Citations: 45     Fields:    Translation:AnimalsCells
    241. Rosenquist TH, Bennett GD, Brauer PR, Stewart ML, Chaudoin TR, Finnell RH. Microarray analysis of homocysteine-responsive genes in cardiac neural crest cells in vitro. Dev Dyn. 2007 Apr; 236(4):1044-54. PMID: 17326132.
      Citations: 7     Fields:    Translation:AnimalsCells
    242. Zhu H, Wlodarczyk BJ, Scott M, Yu W, Merriweather M, Gelineau-van Waes J, Schwartz RJ, Finnell RH. Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. Birth Defects Res A Clin Mol Teratol. 2007 Apr; 79(4):257-68. PMID: 17286298.
      Citations: 16     Fields:    Translation:Animals
    243. Zhu H, Enaw JO, Ma C, Shaw GM, Lammer EJ, Finnell RH. Association between CFL1 gene polymorphisms and spina bifida risk in a California population. BMC Med Genet. 2007 Mar 12; 8:12. PMID: 17352815; PMCID: PMC1831766.
      Citations: 9     Fields:    Translation:Humans
    244. Perret C, Bahuau M, Zhu H, Herman C, Francannet C, Robert-Gnansia E, Finnell RH, Cordier S, Chevrier C, Nelva A. Fetal and maternal MTHFR C677T genotype, maternal folate intake and the risk of nonsyndromic oral clefts. Am J Med Genet A. 2007 Feb 01; 143A(3):248-57. PMID: 17219389.
      Citations: 20     Fields:    Translation:Humans
    245. Taparia S, Rosenquist TH, Finnell RH, Gelineau-van Waes J. Importance of folate-homocysteine homeostasis during early embryonic development. Clin Chem Lab Med. 2007; 45(12):1717-27. PMID: 18067451.
      Citations: 24     Fields:    Translation:Animals
    246. Lu W, Zhu H, Wen S, Laurent C, Shaw GM, Lammer EJ, Finnell RH. Screening for novel PAX3 polymorphisms and risks of spina bifida. Birth Defects Res A Clin Mol Teratol. 2007 Jan; 79(1):45-9. PMID: 17149730; PMCID: PMC6532638.
      Citations: 9     Fields:    Translation:Humans
    247. Shaw GM, Jelliffe-Pawlowski L, Nelson V, Zhu H, Harris JA, Finnell RH. Infant C677T MTHFR polymorphism and severe mental retardation. Birth Defects Res A Clin Mol Teratol. 2007 Jan; 79(1):24-6. PMID: 17149733.
      Citations:    Fields:    Translation:Humans
    248. Enaw JO, Zhu H, Yang W, Lu W, Shaw GM, Lammer EJ, Finnell RH. CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population. BMC Med. 2006 Dec 21; 4:36. PMID: 17184542; PMCID: PMC1770928.
      Citations: 14     Fields:    Translation:Humans
    249. Carmichael SL, Shaw GM, Iovannisci DM, Yang W, Finnell RH, Cheng S, Lammer EJ. Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation. Am J Med Genet A. 2006 Nov 15; 140(22):2433-40. PMID: 17036337.
      Citations: 6     Fields:    Translation:Humans
    250. Rosenquist TH, Finnell RH. Another key role for the cardiac neural crest in heart development. Am J Physiol Heart Circ Physiol. 2007 Mar; 292(3):H1225-6. PMID: 17098821.
      Citations: 2     Fields:    Translation:Animals
    251. Sobol E, Yagen B, Lamb JG, White HS, Wlodarczyk BJ, Finnell RH, Bialer M. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide. Epilepsy Res. 2007 Jan; 73(1):75-84. PMID: 16997532.
      Citations: 1     Fields:    Translation:Animals
    252. Lawrance AK, Deng L, Brody LC, Finnell RH, Shane B, Rozen R. Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. J Nutr Biochem. 2007 May; 18(5):305-12. PMID: 16963246.
      Citations: 7     Fields:    Translation:AnimalsCells
    253. Blom HJ, Shaw GM, den Heijer M, Finnell RH. Neural tube defects and folate: case far from closed. Nat Rev Neurosci. 2006 Sep; 7(9):724-31. PMID: 16924261; PMCID: PMC2970514.
      Citations: 159     Fields:    Translation:HumansAnimalsCells
    254. Meador KJ, Baker GA, Finnell RH, Kalayjian LA, Liporace JD, Loring DW, Mawer G, Pennell PB, Smith JC, Wolff MC, NEAD Study Group. In utero antiepileptic drug exposure: fetal death and malformations. Neurology. 2006 Aug 08; 67(3):407-12. PMID: 16894099; PMCID: PMC1986655.
      Citations: 71     Fields:    Translation:Humans
    255. Sobol E, Yagen B, Steve White H, Wilcox KS, Lamb JG, Pappo O, Wlodarczyk BJ, Finnell RH, Bialer M. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug. Neuropharmacology. 2006 Sep; 51(4):933-46. PMID: 16890251.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    256. Wlodarczyk BJ, Cabrera RM, Hill DS, Bozinov D, Zhu H, Finnell RH. Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos. Neurotoxicology. 2006 Jul; 27(4):547-57. PMID: 16620997.
      Citations: 12     Fields:    Translation:Animals
    257. Zhang J, Zhu H, Yang W, Shaw GM, Lammer EJ, Finnell RH. Phosphatidylethanolamine N-methyltransferase (PEMT) gene polymorphisms and risk of spina bifida. Am J Med Genet A. 2006 Apr 01; 140(7):785-9. PMID: 16523512; PMCID: PMC2970521.
      Citations: 7     Fields:    Translation:Humans
    258. Zhu J, Ren A, Hao L, Pei L, Liu J, Zhu H, Li S, Finnell RH, Li Z. Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China. Am J Med Genet A. 2006 Mar 15; 140(6):551-7. PMID: 16470725.
      Citations: 10     Fields:    Translation:Humans
    259. Massa V, Wlodarczyk B, Giavini E, Finnell RH. Myo-inositol enhances teratogenicity of valproic acid in the mouse. Birth Defects Res A Clin Mol Teratol. 2006 Mar; 76(3):200-4. PMID: 16511884.
      Citations: 4     Fields:    Translation:Animals
    260. Abdelrahim M, Ariazi E, Kim K, Khan S, Barhoumi R, Burghardt R, Liu S, Hill D, Finnell R, Wlodarczyk B, Jordan VC, Safe S. 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer Res. 2006 Feb 15; 66(4):2459-67. PMID: 16489053.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    261. Shaw GM, Iovannisci DM, Yang W, Finnell RH, Carmichael SL, Cheng S, Lammer EJ. Endothelial nitric oxide synthase (NOS3) genetic variants, maternal smoking, vitamin use, and risk of human orofacial clefts. Am J Epidemiol. 2005 Dec 15; 162(12):1207-14. PMID: 16269583.
      Citations: 16     Fields:    Translation:HumansPHPublic Health
    262. Massa V, Cabrera RM, Menegola E, Giavini E, Finnell RH. Valproic acid-induced skeletal malformations: associated gene expression cascades. Pharmacogenet Genomics. 2005 Nov; 15(11):787-800. PMID: 16220111.
      Citations: 12     Fields:    Translation:HumansAnimals
    263. Zhu H, Yang W, Lu W, Zhang J, Shaw GM, Lammer EJ, Finnell RH. A known functional polymorphism (Ile120Val) of the human PCMT1 gene and risk of spina bifida. Mol Genet Metab. 2006 Jan; 87(1):66-70. PMID: 16256389; PMCID: PMC2947858.
      Citations: 10     Fields:    Translation:Humans
    264. Wlodarczyk BJ, Tang LS, Triplett A, Aleman F, Finnell RH. Spontaneous neural tube defects in splotch mice supplemented with selected micronutrients. Toxicol Appl Pharmacol. 2006 May 15; 213(1):55-63. PMID: 16226775.
      Citations: 28     Fields:    Translation:Animals
    265. Shaw GM, Iovannisci DM, Yang W, Finnell RH, Carmichael SL, Cheng S, Lammer EJ. Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes. Am J Med Genet A. 2005 Sep 15; 138(1):21-6. PMID: 16100725.
      Citations: 29     Fields:    Translation:Humans
    266. Lammer EJ, Shaw GM, Iovannisci DM, Finnell RH. Maternal smoking, genetic variation of glutathione s-transferases, and risk for orofacial clefts. Epidemiology. 2005 Sep; 16(5):698-701. PMID: 16135950.
      Citations: 25     Fields:    Translation:HumansPHPublic Health
    267. Blanton SH, Cortez A, Stal S, Mulliken JB, Finnell RH, Hecht JT. Variation in IRF6 contributes to nonsyndromic cleft lip and palate. Am J Med Genet A. 2005 Sep 01; 137A(3):259-62. PMID: 16096995.
      Citations: 51     Fields:    Translation:Humans
    268. Zhu H, Lu W, Laurent C, Shaw GM, Lammer EJ, Finnell RH. Genes encoding catalytic subunits of protein kinase A and risk of spina bifida. Birth Defects Res A Clin Mol Teratol. 2005 Sep; 73(9):591-6. PMID: 16080189; PMCID: PMC2970525.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    269. Shaw GM, Carmichael SL, Yang W, Harris JA, Finnell RH, Lammer EJ. Epidemiologic characteristics of anophthalmia and bilateral microphthalmia among 2.5 million births in California, 1989-1997. Am J Med Genet A. 2005 Aug 15; 137(1):36-40. PMID: 16007635.
      Citations: 28     Fields:    Translation:Humans
    270. Lu W, Volcik K, Zhu H, Wen S, Shaw GM, Lammer EJ, Finnell RH. Genetic variation in the proto-oncogene SKI and risk for orofacial clefting. Mol Genet Metab. 2005 Nov; 86(3):412-6. PMID: 16054854.
      Citations: 2     Fields:    Translation:Humans
    271. Pei L, Zhu H, Zhu J, Ren A, Finnell RH, Li Z. Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial defects and congenital heart defects in China. Ann Epidemiol. 2006 May; 16(5):352-6. PMID: 16019224.
      Citations: 21     Fields:    Translation:Humans
    272. Zhu H, Curry S, Wen S, Wicker NJ, Shaw GM, Lammer EJ, Yang W, Jafarov T, Finnell RH. Are the betaine-homocysteine methyltransferase (BHMT and BHMT2) genes risk factors for spina bifida and orofacial clefts? Am J Med Genet A. 2005 Jun 15; 135(3):274-7. PMID: 15887275.
      Citations: 28     Fields:    Translation:HumansPHPublic Health
    273. Olshan AF, Shaw GM, Millikan RC, Laurent C, Finnell RH. Polymorphisms in DNA repair genes as risk factors for spina bifida and orofacial clefts. Am J Med Genet A. 2005 Jun 15; 135(3):268-73. PMID: 15887293.
      Citations: 18     Fields:    Translation:HumansCellsPHPublic Health
    274. Pei L, Zhu H, Ren A, Li Z, Hao L, Finnell RH, Li Z. Reduced folate carrier gene is a risk factor for neural tube defects in a Chinese population. Birth Defects Res A Clin Mol Teratol. 2005 Jun; 73(6):430-3. PMID: 15799025.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    275. Tang LS, Santillano DR, Wlodarczyk BJ, Miranda RC, Finnell RH. Role of Folbp1 in the regional regulation of apoptosis and cell proliferation in the developing neural tube and craniofacies. Am J Med Genet C Semin Med Genet. 2005 May 15; 135C(1):48-58. PMID: 15800851.
      Citations: 13     Fields:    Translation:AnimalsCells
    276. Moretti P, Sahoo T, Hyland K, Bottiglieri T, Peters S, del Gaudio D, Roa B, Curry S, Zhu H, Finnell RH, Neul JL, Ramaekers VT, Blau N, Bacino CA, Miller G, Scaglia F. Cerebral folate deficiency with developmental delay, autism, and response to folinic acid. Neurology. 2005 Mar 22; 64(6):1088-90. PMID: 15781839.
      Citations: 41     Fields:    Translation:Humans
    277. Spiegelstein O, Gould A, Wlodarczyk B, Tsie M, Lu X, Le C, Troen A, Selhub J, Piedrahita JA, Salbaum JM, Kappen C, Melnyk S, James J, Finnell RH. Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies. Toxicol Appl Pharmacol. 2005 Feb 15; 203(1):18-26. PMID: 15694460; PMCID: PMC3938173.
      Citations: 12     Fields:    Translation:Animals
    278. Birn H, Spiegelstein O, Christensen EI, Finnell RH. Renal tubular reabsorption of folate mediated by folate binding protein 1. J Am Soc Nephrol. 2005 Mar; 16(3):608-15. PMID: 15703271.
      Citations: 35     Fields:    Translation:AnimalsCells
    279. Jafarov T, Zhu H, Finnell R, Kulieva S. Epidemiologic study on HFE C282Y mutation in Azerbaijan. Eur J Haematol. 2005 Feb; 74(2):180-1. PMID: 15654913.
      Citations:    Fields:    Translation:Humans
    280. Ma DW, Finnell RH, Davidson LA, Callaway ES, Spiegelstein O, Piedrahita JA, Salbaum JM, Kappen C, Weeks BR, James J, Bozinov D, Lupton JR, Chapkin RS. Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis. Cancer Res. 2005 Feb 01; 65(3):887-97. PMID: 15705887; PMCID: PMC3938162.
      Citations: 23     Fields:    Translation:Animals
    281. Rosenquist TH, van Waes JG, Shaw GM, Finnell R. Nutrient effects upon embryogenesis: folate, vitamin A and iodine. Nestle Nutr Workshop Ser Pediatr Program. 2005; 55:29-40; discussion 40-8. PMID: 16632927.
      Citations: 1     Fields:    Translation:Humans
    282. Spiegelstein O, Lu X, Le XC, Troen A, Selhub J, Melnyk S, James SJ, Finnell RH. Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice. Environ Toxicol Pharmacol. 2005 Jan; 19(1):1-7. PMID: 21783456.
      Citations: 11     Fields:    
    283. Cabrera RM, Hill DS, Etheredge AJ, Finnell RH. Investigations into the etiology of neural tube defects. Birth Defects Res C Embryo Today. 2004 Dec; 72(4):330-44. PMID: 15662706.
      Citations: 18     Fields:    Translation:Humans
    284. Lammer EJ, Shaw GM, Iovannisci DM, Finnell RH. Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for orofacial clefts. Birth Defects Res A Clin Mol Teratol. 2004 Nov; 70(11):846-52. PMID: 15523664.
      Citations: 22     Fields:    Translation:Humans
    285. Spiegelstein O, Mitchell LE, Merriweather MY, Wicker NJ, Zhang Q, Lammer EJ, Finnell RH. Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation. Dev Dyn. 2004 Sep; 231(1):221-31. PMID: 15305303.
      Citations: 37     Fields:    Translation:Animals
    286. Finnell RH, Shaw GM, Lammer EJ, Brandl KL, Carmichael SL, Rosenquist TH. Gene-nutrient interactions: importance of folates and retinoids during early embryogenesis. Toxicol Appl Pharmacol. 2004 Jul 15; 198(2):75-85. PMID: 15236946.
      Citations: 19     Fields:    Translation:HumansAnimalsPHPublic Health
    287. Kappen C, Mello MA, Finnell RH, Salbaum JM. Folate modulates Hox gene-controlled skeletal phenotypes. Genesis. 2004 Jul; 39(3):155-66. PMID: 15282741; PMCID: PMC3938166.
      Citations: 9     Fields:    Translation:Animals
    288. Tang LS, Wlodarczyk BJ, Santillano DR, Miranda RC, Finnell RH. Developmental consequences of abnormal folate transport during murine heart morphogenesis. Birth Defects Res A Clin Mol Teratol. 2004 Jul; 70(7):449-58. PMID: 15259034.
      Citations: 17     Fields:    Translation:AnimalsCells
    289. Spiegelstein O, Cabrera RM, Bozinov D, Wlodarczyk B, Finnell RH. Folate-regulated changes in gene expression in the anterior neural tube of folate binding protein-1 (Folbp1)-deficient murine embryos. Neurochem Res. 2004 Jun; 29(6):1105-12. PMID: 15176467.
      Citations: 8     Fields:    Translation:AnimalsCells
    290. Lundberg YW, Cabrera RM, Greer KA, Zhao J, Garg R, Finnell RH. Mapping a chromosomal locus for valproic acid-induced exencephaly in mice. Mamm Genome. 2004 May; 15(5):361-9. PMID: 15170225.
      Citations: 7     Fields:    Translation:AnimalsPHPublic Health
    291. Volcik KA, Zhu H, Finnell RH, Shaw GM, Canfield M, Lammer EJ. Evaluation of the Cited2 gene and risk for spina bifida and congenital heart defects. Am J Med Genet A. 2004 Apr 30; 126A(3):324-5. PMID: 15054851.
      Citations: 8     Fields:    Translation:Humans
    292. Volcik KA, Zhu H, Finnell RH, Shaw GM, Canfield M, Lammer EJ. Evaluation of the jumonji gene and risk for spina bifida and congenital heart defects. Am J Med Genet A. 2004 Apr 15; 126A(2):215-7. PMID: 15057990.
      Citations: 8     Fields:    Translation:Humans
    293. Carmichael SL, Shaw GM, Yang W, Lammer EJ, Zhu H, Finnell RH. Limb deficiency defects, MSX1, and exposure to tobacco smoke. Am J Med Genet A. 2004 Mar 15; 125A(3):285-9. PMID: 14994238.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    294. Lammer EJ, Shaw GM, Iovannisci DM, Van Waes J, Finnell RH. Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms. Epidemiology. 2004 Mar; 15(2):150-6. PMID: 15127906.
      Citations: 34     Fields:    Translation:Humans
    295. Zhu H, Wicker NJ, Volcik K, Zhang J, Shaw GM, Lammer EJ, Suarez L, Canfield M, Finnell RH. Promoter haplotype combinations for the human PDGFRA gene are associated with risk of neural tube defects. Mol Genet Metab. 2004 Feb; 81(2):127-32. PMID: 14741194.
      Citations: 10     Fields:    Translation:HumansCells
    296. Spiegelstein O, Chatterjie N, Alexander G, Finnell RH. Teratogenicity of valproate conjugates with anticonvulsant activity in mice. Epilepsy Res. 2003 Dec; 57(2-3):145-52. PMID: 15013055.
      Citations: 2     Fields:    Translation:Animals
    297. Spiegelstein O, Merriweather MY, Wicker NJ, Finnell RH. Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice. Birth Defects Res A Clin Mol Teratol. 2003 Dec; 67(12):974-8. PMID: 14745917.
      Citations: 8     Fields:    Translation:Animals
    298. Spiegelstein O, Lu X, Le XC, Troen A, Selhub J, Melnyk S, James SJ, Finnell RH. Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicol Lett. 2003 Nov 30; 145(2):167-74. PMID: 14581169.
      Citations: 19     Fields:    Translation:Animals
    299. Volcik KA, Shaw GM, Zhu H, Lammer EJ, Laurent C, Finnell RH. Associations between polymorphisms within the thymidylate synthase gene and spina bifida. Birth Defects Res A Clin Mol Teratol. 2003 Nov; 67(11):924-8. PMID: 14745930.
      Citations: 19     Fields:    Translation:Humans
    300. Shaw GM, Zhu H, Lammer EJ, Yang W, Finnell RH. Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial and conotruncal heart defects. Am J Epidemiol. 2003 Oct 15; 158(8):747-52. PMID: 14561664.
      Citations: 22     Fields:    Translation:Humans
    301. Isoherranen N, Spiegelstein O, Bialer M, Zhang J, Merriweather M, Yagen B, Roeder M, Triplett AA, Schurig V, Finnell RH. Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity. Epilepsia. 2003 Oct; 44(10):1280-8. PMID: 14510821.
      Citations: 8     Fields:    Translation:Animals
    302. Heil SG, Kluijtmans LA, Spiegelstein O, Finnell RH, Blom HJ. Gene-specific monitoring of T7-based RNA amplification by real-time quantitative PCR. Biotechniques. 2003 Sep; 35(3):502-4, 506-8. PMID: 14513555.
      Citations: 2     Fields:    Translation:Cells
    303. Morin I, Devlin AM, Leclerc D, Sabbaghian N, Halsted CH, Finnell R, Rozen R. Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk. Mol Genet Metab. 2003 Jul; 79(3):197-200. PMID: 12855225.
      Citations: 18     Fields:    Translation:Humans
    304. Lundberg YW, Wing MJ, Xiong W, Zhao J, Finnell RH. Genetic dissection of hyperthermia-induced neural tube defects in mice. Birth Defects Res A Clin Mol Teratol. 2003 Jun; 67(6):409-13. PMID: 12962284.
      Citations: 11     Fields:    Translation:AnimalsPHPublic Health
    305. Isoherranen N, Yagen B, Spiegelstein O, Finnell RH, Merriweather M, Woodhead JH, Wlodarczyk B, White HS, Bialer M. Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice. Br J Pharmacol. 2003 Jun; 139(4):755-64. PMID: 12812999; PMCID: PMC1573897.
      Citations: 6     Fields:    Translation:AnimalsCells
    306. Isoherranen N, Yagen B, Spiegelstein O, Steinman A, Finnell RH, Bialer M. Gas chromatographic determination of novel valproyl taurinamide derivatives in mouse and dog plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 May 05; 788(1):125-36. PMID: 12668078.
      Citations: 1     Fields:    Translation:Animals
    307. Tang LS, Finnell RH. Neural and orofacial defects in Folp1 knockout mice [corrected]. Birth Defects Res A Clin Mol Teratol. 2003 Apr; 67(4):209-18. PMID: 12854656.
      Citations: 27     Fields:    Translation:Animals
    308. Shaw GM, Nelson V, Iovannisci DM, Finnell RH, Lammer EJ. Maternal occupational chemical exposures and biotransformation genotypes as risk factors for selected congenital anomalies. Am J Epidemiol. 2003 Mar 15; 157(6):475-84. PMID: 12631536.
      Citations: 21     Fields:    Translation:HumansPHPublic Health
    309. De Marco P, Calevo MG, Moroni A, Merello E, Raso A, Finnell RH, Zhu H, Andreussi L, Cama A, Capra V. Reduced folate carrier polymorphism (80A-->G) and neural tube defects. Eur J Hum Genet. 2003 Mar; 11(3):245-52. PMID: 12673279.
      Citations: 30     Fields:    Translation:Humans
    310. Zhu H, Wicker NJ, Shaw GM, Lammer EJ, Hendricks K, Suarez L, Canfield M, Finnell RH. Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects. Mol Genet Metab. 2003 Mar; 78(3):216-21. PMID: 12649067.
      Citations: 35     Fields:    Translation:HumansCells
    311. Volcik KA, Shaw GM, Lammer EJ, Zhu H, Finnell RH. Evaluation of infant methylenetetrahydrofolate reductase genotype, maternal vitamin use, and risk of high versus low level spina bifida defects. Birth Defects Res A Clin Mol Teratol. 2003 Mar; 67(3):154-7. PMID: 12797455.
      Citations: 6     Fields:    Translation:Humans
    312. Volcik KA, Shaw GM, Zhu H, Lammer EJ, Finnell RH. Risk factors for neural tube defects: associations between uncoupling protein 2 polymorphisms and spina bifida. Birth Defects Res A Clin Mol Teratol. 2003 Mar; 67(3):158-61. PMID: 12797456.
      Citations: 8     Fields:    Translation:Humans
    313. Zhu H, Barber R, Shaw GM, Lammer EJ, Finnell RH. Is Sonic hedgehog (SHH) a candidate gene for spina bifida? A pilot study. Am J Med Genet A. 2003 Feb 15; 117A(1):87-8. PMID: 12548748.
      Citations: 1     Fields:    Translation:Humans
    314. Zhu H, Junker WM, Finnell RH, Brown S, Shaw GM, Lammer EJ, Canfield M, Hendricks K. Lack of association between ZIC2 and ZIC3 genes and the risk of neural tube defects (NTDs) in Hispanic populations. Am J Med Genet A. 2003 Feb 01; 116A(4):414-5. PMID: 12522805.
      Citations: 3     Fields:    Translation:Humans
    315. Isoherranen N, Yagen B, Spiegelstein O, Blotnik S, Wilcox KS, Finnell RH, Bennett GD, White HS, Bialer M, Woodhead JH. Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents. Br J Pharmacol. 2003 Feb; 138(4):602-13. PMID: 12598414; PMCID: PMC1573693.
      Citations: 6     Fields:    Translation:AnimalsCells
    316. Finnell RH, Gould A, Spiegelstein O. Pathobiology and genetics of neural tube defects. Epilepsia. 2003; 44 Suppl 3:14-23. PMID: 12790882.
      Citations: 17     Fields:    Translation:HumansAnimals
    317. Shaw GM, Nelson V, Carmichael SL, Lammer EJ, Finnell RH, Rosenquist TH. Maternal periconceptional vitamins: interactions with selected factors and congenital anomalies? Epidemiology. 2002 Nov; 13(6):625-30. PMID: 12410002.
      Citations: 22     Fields:    Translation:Humans
    318. Volcik KA, Zhu H, Shaw GM, Lammer EJ, Finnell RH. Apolipoprotein E and apolipoprotein B genotypes and risk for spina bifida. Teratology. 2002 Nov; 66(5):257-9. PMID: 12397634.
      Citations: 2     Fields:    Translation:Humans
    319. Rasmussen SA, Lammer EJ, Shaw GM, Finnell RH, McGehee RE, Gallagher M, Romitti PA, Murray JC, National Birth Defects Prevention Study. Integration of DNA sample collection into a multi-site birth defects case-control study. Teratology. 2002 Oct; 66(4):177-84. PMID: 12353214.
      Citations: 27     Fields:    Translation:HumansPHPublic Health
    320. Finnell RH, Junker WM, Wadman LK, Cabrera RM. Gene expression profiling within the developing neural tube. Neurochem Res. 2002 Oct; 27(10):1165-80. PMID: 12462415.
      Citations: 4     Fields:    Translation:Animals
    321. Finnell RH, Spiegelstein O, Wlodarczyk B, Triplett A, Pogribny IP, Melnyk S, James JS. DNA methylation in Folbp1 knockout mice supplemented with folic acid during gestation. J Nutr. 2002 08; 132(8 Suppl):2457S-2461S. PMID: 12163711.
      Citations: 22     Fields:    Translation:AnimalsCells
    322. Shaw GM, Lammer EJ, Zhu H, Baker MW, Neri E, Finnell RH. Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida. Am J Med Genet. 2002 Feb 15; 108(1):1-6. PMID: 11857541.
      Citations: 35     Fields:    Translation:Humans
    323. Croen LA, Shaw GM, Barber RC, Baker MM, Finnell RH, Lammer EJ. Apolipoprotein B and apolipoprotein E genotypes and sporadic holoprosencephaly. Am J Med Genet. 2002 Feb 15; 108(1):75-7. PMID: 11857554.
      Citations:    Fields:    Translation:Humans
    324. Gefrides LA, Bennett GD, Finnell RH. Effects of folate supplementation on the risk of spontaneous and induced neural tube defects in Splotch mice. Teratology. 2002 Feb; 65(2):63-9. PMID: 11857507.
      Citations: 7     Fields:    Translation:Animals
    325. Isoherranen N, White HS, Finnell RH, Yagen B, Bennett GD, Wilcox KS, Barton ME, Bialer M, Woodhead JH. Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug. Epilepsia. 2002 Feb; 43(2):115-26. PMID: 11903457.
      Citations: 4     Fields:    Translation:Animals
    326. Finnell RH, Waes JG, Eudy JD, Rosenquist TH. Molecular basis of environmentally induced birth defects. Annu Rev Pharmacol Toxicol. 2002; 42:181-208. PMID: 11807170.
      Citations: 26     Fields:    Translation:HumansAnimals
    327. Finnell RH, Shaw GM, Lammer EJ, Volcik KA. Does prenatal screening for 5,10-methylenetetrahydrofolate reductase (MTHFR) mutations in high-risk neural tube defect pregnancies make sense? Genet Test. 2002; 6(1):47-52. PMID: 12180076.
      Citations: 6     Fields:    Translation:HumansAnimals
    328. De Marco P, Calevo MG, Moroni A, Arata L, Merello E, Finnell RH, Zhu H, Andreussi L, Cama A, Capra V. Study of MTHFR and MS polymorphisms as risk factors for NTD in the Italian population. J Hum Genet. 2002; 47(6):319-24. PMID: 12111380.
      Citations: 33     Fields:    Translation:Humans
    329. Wlodarczyk B, Spiegelstein O, Gelineau-van Waes J, Vorce RL, Lu X, Le CX, Finnell RH. Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice. Toxicol Appl Pharmacol. 2001 Dec 15; 177(3):238-46. PMID: 11749123.
      Citations: 23     Fields:    Translation:Animals
    330. De Marco P, Calevo MG, Moroni A, Arata L, Merello E, Cama A, Finnell RH, Andreussi L, Capra V. Polymorphisms in genes involved in folate metabolism as risk factors for NTDs. Eur J Pediatr Surg. 2001 Dec; 11 Suppl 1:S14-7. PMID: 11813127.
      Citations: 12     Fields:    Translation:Humans
    331. Waes JG, Finnell RH. Importance of model organisms in understanding the biology and genetic basis of human nonsyndromic neural tube defects. Teratology. 2001 Oct; 64(4):177-80. PMID: 11598923.
      Citations:    Fields:    Translation:HumansAnimals
    332. Gelineau-van Waes J, Finnell RH. Genetics of neural tube defects. Semin Pediatr Neurol. 2001 Sep; 8(3):160-4. PMID: 11575845.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    333. Boecker J, Richter B, Capra V, Finnell RH, Ngo ET, Strehl E, Ermert A, Koch MC, Stegmann K. A screen for mutations in human homologues of mice exencephaly genes Tfap2alpha and Msx2 in patients with neural tube defects. Teratology. 2001 May; 63(5):167-75. PMID: 11320527.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    334. Rosenquist TH, Finnell RH. Genes, folate and homocysteine in embryonic development. Proc Nutr Soc. 2001 Feb; 60(1):53-61. PMID: 11310424.
      Citations: 17     Fields:    Translation:HumansAnimals
    335. Eudy JD, Spiegelstein O, Barber RC, Wlodarczyk BJ, Talbot J, Finnell RH. Identification and characterization of the human and mouse SLC19A3 gene: a novel member of the reduced folate family of micronutrient transporter genes. Mol Genet Metab. 2000 Dec; 71(4):581-90. PMID: 11136550.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    336. Spiegelstein O, Eudy JD, Finnell RH. Identification of two putative novel folate receptor genes in humans and mouse. Gene. 2000 Nov 27; 258(1-2):117-25. PMID: 11111049.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    337. De Marco P, Moroni A, Merello E, de Franchis R, Andreussi L, Finnell RH, Barber RC, Cama A, Capra V. Folate pathway gene alterations in patients with neural tube defects. Am J Med Genet. 2000 Nov 27; 95(3):216-23. PMID: 11102926.
      Citations: 8     Fields:    Translation:HumansCells
    338. Ruan Y, Peterson MH, Wauson EM, Waes JG, Finnell RH, Vorce RL. Folic acid protects SWV/Fnn embryo fibroblasts against arsenic toxicity. Toxicol Lett. 2000 Nov 20; 117(3):129-37. PMID: 11087978.
      Citations: 5     Fields:    Translation:AnimalsCells
    339. Finnell RH, Burn J. Effect of anti-epileptic drugs on intrauterine growth. Lancet. 2000 Nov 04; 356(9241):1537-8. PMID: 11075761.
      Citations: 1     Fields:    Translation:Humans
    340. Spiegelstein O, Yagen B, Bennett GD, Finnell RH, Blotnik S, Bialer M. Stereoselective pharmacokinetic analysis of valnoctamide, a CNS-active chiral amide analogue of valproic acid, in dogs, rats, and mice. Ther Drug Monit. 2000 Oct; 22(5):574-81. PMID: 11034263.
      Citations: 3     Fields:    Translation:HumansAnimals
    341. Joachims Z, Joachims HZ, Golz A, Hefer T, Finnell RH. Heredity in large vestibular aqueduct syndrome. J Otolaryngol. 2000 Aug; 29(4):244-6. PMID: 11003078.
      Citations:    Fields:    Translation:Humans
    342. Shaw GM, Todoroff K, Finnell RH, Lammer EJ. Spina bifida phenotypes in infants or fetuses of obese mothers. Teratology. 2000 May; 61(5):376-81. PMID: 10777833.
      Citations: 11     Fields:    Translation:Humans
    343. Barber R, Shalat S, Hendricks K, Joggerst B, Larsen R, Suarez L, Finnell R. Investigation of folate pathway gene polymorphisms and the incidence of neural tube defects in a Texas hispanic population. Mol Genet Metab. 2000 May; 70(1):45-52. PMID: 10833330.
      Citations: 21     Fields:    Translation:HumansCells
    344. Craig JC, Bennett GD, Miranda RC, Mackler SA, Finnell RH. Ribonucleotide reductase subunit R1: a gene conferring sensitivity to valproic acid-induced neural tube defects in mice. Teratology. 2000 Apr; 61(4):305-13. PMID: 10716750.
      Citations: 4     Fields:    Translation:AnimalsCells
    345. Shaw GM, Barber R, Todoroff K, Lammer EJ, Finnell RH. Microsatellites proximal to leptin and leptin receptor as risk factors for spina bifida. Teratology. 2000 Mar; 61(3):231-5. PMID: 10661913.
      Citations: 5     Fields:    Translation:HumansCells
    346. Finnell RH, Gelineau-van Waes J, Bennett GD, Barber RC, Wlodarczyk B, Shaw GM, Lammer EJ, Piedrahita JA, Eberwine JH. Genetic basis of susceptibility to environmentally induced neural tube defects. Ann N Y Acad Sci. 2000; 919:261-77. PMID: 11083116.
      Citations: 14     Fields:    Translation:HumansAnimals
    347. Bennett GD, Wlodarczyk B, Calvin JA, Craig JC, Finnell RH. Valproic acid-induced alterations in growth and neurotrophic factor gene expression in murine embryos [corrected]. Reprod Toxicol. 2000 Jan-Feb; 14(1):1-11. PMID: 10689198.
      Citations: 9     Fields:    Translation:AnimalsCells
    348. Piedrahita JA, Oetama B, Bennett GD, van Waes J, Kamen BA, Richardson J, Lacey SW, Anderson RG, Finnell RH. Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nat Genet. 1999 Oct; 23(2):228-32. PMID: 10508523.
      Citations: 110     Fields:    Translation:AnimalsCells
    349. Spiegelstein O, Yagen B, Levy RH, Finnell RH, Bennett GD, Roeder M, Schurig V, Bialer M. Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid. Pharm Res. 1999 Oct; 16(10):1582-8. PMID: 10554101.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    350. Rao VH, Singh RK, Delimont DC, Schaefer GB, Bridge JA, Neff JR, Sanger WG, Sappenfield JW, Buehler BA, Finnell RH. Interleukin-1beta upregulates MMP-9 expression in stromal cells of human giant cell tumor of bone. J Interferon Cytokine Res. 1999 Oct; 19(10):1207-17. PMID: 10547161.
      Citations: 3     Fields:    Translation:HumansCells
    351. McAlhany RE, Miranda RC, Finnell RH, West JR. Ethanol decreases Glial-Derived Neurotrophic Factor (GDNF) protein release but not mRNA expression and increases GDNF-stimulated Shc phosphorylation in the developing cerebellum. Alcohol Clin Exp Res. 1999 Oct; 23(10):1691-7. PMID: 10550003.
      Citations: 11     Fields:    Translation:AnimalsCells
    352. Shaw GM, Todoroff K, Finnell RH, Rozen R, Lammer EJ. Maternal vitamin use, infant C677T mutation in MTHFR, and isolated cleft palate risk. Am J Med Genet. 1999 Jul 02; 85(1):84-5. PMID: 10377018.
      Citations: 8     Fields:    Translation:Humans
    353. Trembath D, Sherbondy AL, Vandyke DC, Shaw GM, Todoroff K, Lammer EJ, Finnell RH, Marker S, Lerner G, Murray JC. Analysis of select folate pathway genes, PAX3, and human T in a Midwestern neural tube defect population. Teratology. 1999 May; 59(5):331-41. PMID: 10332959.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    354. Finnell RH, Bennett GD, Mather GG, Wlodarczyk B, Bajpai M, Levy RH. Effect of stiripentol dose on phenytoin-induced teratogenesis in a mouse model. Reprod Toxicol. 1999 Mar-Apr; 13(2):85-91. PMID: 10213515.
      Citations: 3     Fields:    Translation:Animals
    355. Rao VH, Singh RK, Delimont DC, Finnell RH, Bridge JA, Neff JR, Garvin BP, Pickering DL, Sanger WG, Buehler BA, Schaefer GB. Transcriptional regulation of MMP-9 expression in stromal cells of human giant cell tumor of bone by tumor necrosis factor-alpha. Int J Oncol. 1999 Feb; 14(2):291-300. PMID: 9917505.
      Citations: 4     Fields:    Translation:HumansCells
    356. Finnell RH. Teratology: general considerations and principles. J Allergy Clin Immunol. 1999 Feb; 103(2 Pt 2):S337-42. PMID: 9949334.
      Citations: 21     Fields:    Translation:Humans
    357. Shaw GM, Todoroff K, Finnell RH, Lammer EJ, Leclerc D, Gravel RA, Rozen R. Infant methionine synthase variants and risk for spina bifida. J Med Genet. 1999 Jan; 36(1):86-7. PMID: 9950377; PMCID: PMC1762959.
      Citations: 6     Fields:    Translation:Humans
    358. Barber RC, Lammer EJ, Shaw GM, Greer KA, Finnell RH. The role of folate transport and metabolism in neural tube defect risk. Mol Genet Metab. 1999 Jan; 66(1):1-9. PMID: 9973541.
      Citations: 10     Fields:    Translation:Humans
    359. Barber RC, Bennett GD, Greer KA, Finnell RH. Expression patterns of folate binding proteins one and two in the developing mouse embryo. Mol Genet Metab. 1999 Jan; 66(1):31-9. PMID: 9973545.
      Citations: 11     Fields:    Translation:Animals
    360. Koebbe MJ, Golden JA, Bennett G, Finnell RH, Mackler SA. Effects of prenatal cocaine exposure on embryonic expression of sonic hedgehog. Teratology. 1999 Jan; 59(1):12-9. PMID: 9988878.
      Citations:    Fields:    Translation:Animals
    361. Gelineau-van Waes J, Bennett GD, Finnell RH. Phenytoin-induced alterations in craniofacial gene expression. Teratology. 1999 Jan; 59(1):23-34. PMID: 9988880.
      Citations: 4     Fields:    Translation:Animals
    362. Shaw GM, Rozen R, Finnell RH, Todoroff K, Lammer EJ. Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip. Am J Med Genet. 1998 Nov 16; 80(3):196-8. PMID: 9843036.
      Citations: 23     Fields:    Translation:Humans
    363. Hefer T, Joachims HZ, Carlson D, Finnell RH. [Factors associated with the etiology of congenital craniofacial anomalies--Part II]. Harefuah. 1998 Oct; 135(7-8):286-91. PMID: 9885676.
      Citations:    Fields:    Translation:Humans
    364. Hefer T, Joachims HZ, Carlson D, Finnell RH. [Factors associated with the etiology of congenital craniofacial anomalies--Part I]. Harefuah. 1998 Sep; 135(5-6):209-13. PMID: 9885638.
      Citations:    Fields:    Translation:Humans
    365. Shaw GM, Rozen R, Finnell RH, Wasserman CR, Lammer EJ. Maternal vitamin use, genetic variation of infant methylenetetrahydrofolate reductase, and risk for spina bifida. Am J Epidemiol. 1998 Jul 01; 148(1):30-7. PMID: 9663401.
      Citations: 23     Fields:    Translation:Humans
    366. Nair SM, Werkman TR, Craig J, Finnell R, Eberwine JH, Jo?ls M. Corticosteroid regulation of ion channel conductances and mRNA levels in individual hippocampal CA1 neurons. J Neurosci. 1998 Apr 01; 18(7):2685-96. PMID: 9502826; PMCID: PMC6793106.
      Citations: 23     Fields:    Translation:AnimalsCells
    367. Barber RC, Shaw GM, Lammer EJ, Greer KA, Biela TA, Lacey SW, Wasserman CR, Finnell RH. Lack of association between mutations in the folate receptor-alpha gene and spina bifida. Am J Med Genet. 1998 Apr 01; 76(4):310-7. PMID: 9545095.
      Citations: 10     Fields:    Translation:Humans
    368. Bennett GD, An J, Craig JC, Gefrides LA, Calvin JA, Finnell RH. Neurulation abnormalities secondary to altered gene expression in neural tube defect susceptible Splotch embryos. Teratology. 1998 Jan; 57(1):17-29. PMID: 9516748.
      Citations: 5     Fields:    Translation:Animals
    369. Finnell RH, Greer KA, Barber RC, Piedrahita JA. Neural tube and craniofacial defects with special emphasis on folate pathway genes. Crit Rev Oral Biol Med. 1998; 9(1):38-53. PMID: 9488247.
      Citations: 14     Fields:    Translation:HumansAnimals
    370. Amore BM, Kalhorn TF, Skiles GL, Hunter AP, Bennett GD, Finnell RH, Nelson SD, Slattery JT. Characterization of carbamazepine metabolism in a mouse model of carbamazepine teratogenicity. Drug Metab Dispos. 1997 Aug; 25(8):953-62. PMID: 9280403.
      Citations:    Fields:    Translation:Animals
    371. Finnell RH, Wlodarczyk BC, Craig JC, Piedrahita JA, Bennett GD. Strain-dependent alterations in the expression of folate pathway genes following teratogenic exposure to valproic acid in a mouse model. Am J Med Genet. 1997 Jun 13; 70(3):303-11. PMID: 9188671.
      Citations: 8     Fields:    Translation:Animals
    372. Craig JC, Eberwine JH, Calvin JA, Wlodarczyk B, Bennett GD, Finnell RH. Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med. 1997 Apr; 60(2):81-91. PMID: 9169087.
      Citations: 4     Fields:    Translation:AnimalsCells
    373. Bennett GD, Lau F, Calvin JA, Finnell RH. Phenytoin-induced teratogenesis: a molecular basis for the observed developmental delay during neurulation. Epilepsia. 1997 Apr; 38(4):415-23. PMID: 9118846.
      Citations: 9     Fields:    Translation:Animals
    374. Vacha SJ, Bennett GD, Mackler SA, Koebbe MJ, Finnell RH. Identification of a growth arrest specific (gas 5) gene by differential display as a candidate gene for determining susceptibility to hyperthermia-induced exencephaly in mice. Dev Genet. 1997; 21(3):212-22. PMID: 9397537.
      Citations: 3     Fields:    Translation:AnimalsCells
    375. Wlodarczyk BC, Craig JC, Bennett GD, Calvin JA, Finnell RH. Valproic acid-induced changes in gene expression during neurulation in a mouse model. Teratology. 1996 Dec; 54(6):284-97. PMID: 9098922.
      Citations: 12     Fields:    Translation:Animals
    376. Bennett GD, Amore BM, Finnell RH, Wlodarczyk B, Kalhorn TF, Skiles GL, Nelson SD, Slattery JT. Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse. J Pharmacol Exp Ther. 1996 Dec; 279(3):1237-42. PMID: 8968346.
      Citations: 4     Fields:    Translation:Animals
    377. Wlodarczyk BJ, Bennett GD, Calvin JA, Finnell RH. Arsenic-induced neural tube defects in mice: alterations in cell cycle gene expression. Reprod Toxicol. 1996 Nov-Dec; 10(6):447-54. PMID: 8946558.
      Citations: 19     Fields:    Translation:Animals
    378. Shalat SL, Walker DB, Finnell RH. Role of arsenic as a reproductive toxin with particular attention to neural tube defects. J Toxicol Environ Health. 1996 Jun 28; 48(3):253-72. PMID: 8656449.
      Citations: 17     Fields:    Translation:HumansAnimalsPHPublic Health
    379. Lillibridge JH, Amore BM, Slattery JT, Kalhorn TF, Nelson SD, Finnell RH, Bennett GD. Protein-reactive metabolites of carbamazepine in mouse liver microsomes. Drug Metab Dispos. 1996 May; 24(5):509-14. PMID: 8723729.
      Citations: 10     Fields:    Translation:AnimalsCells
    380. Wlodraczyk B, Bennett GD, Calvin JA, Craig JC, Finnell RH. Arsenic-induced alterations in embryonic transcription factor gene expression: implications for abnormal neural development. Dev Genet. 1996; 18(4):306-15. PMID: 8754282.
      Citations: 7     Fields:    Translation:Animals
    381. Mackler SA, Bennett GD, Tsuei VP, Finnell RH. Cocaine selectively alters neurotransmitter receptor mRNAs in mouse embryos. Reprod Toxicol. 1996 Jan-Feb; 10(1):37-42. PMID: 8998384.
      Citations: 1     Fields:    Translation:AnimalsCells
    382. Craig JC, Westerman ME, Dimichele L, Finnell RH. Screening for reproductive toxicity in Fundulus heteroclitus by genetic expression profiling. Biomarkers. 1996; 1(2):123-35. PMID: 23888923.
      Citations:    Fields:    
    383. Finnell RH, Bennett GD, Slattery JT, Amore BM, Bajpai M, Levy RH. Effect of treatment with phenobarbital and stiripentol on carbamazepine-induced teratogenicity and reactive metabolite formation. Teratology. 1995 Dec; 52(6):324-32. PMID: 8711619.
      Citations: 4     Fields:    Translation:AnimalsCells
    384. Raymond GV, Buehler BA, Finnell RH, Holmes LB. Anticonvulsant teratogenesis: 3. Possible metabolic basis. Teratology. 1995 Feb; 51(2):55-6. PMID: 7660321.
      Citations: 2     Fields:    Translation:HumansCells
    385. Taylor LE, Bennett GD, Finnell RH. Altered gene expression in murine branchial arches following in utero exposure to retinoic acid. J Craniofac Genet Dev Biol. 1995 Jan-Mar; 15(1):13-25. PMID: 7601910.
      Citations: 2     Fields:    Translation:AnimalsCells
    386. Eberwine J, Cao Y, Nair S, Miyashiro K, Mackler S, Finnell R, Surmeier J, Dichter M. Mechanisms of neuronal plasticity as analyzed at the single cell level. Prog Brain Res. 1995; 105:117-26. PMID: 7568870.
      Citations: 4     Fields:    Translation:AnimalsCells
    387. Shaw GM, Wasserman CR, O'Malley CD, Lammer EJ, Finnell RH. Orofacial clefts and maternal anticonvulsant use. Reprod Toxicol. 1995 Jan-Feb; 9(1):97-8. PMID: 8520135.
      Citations: 4     Fields:    Translation:Humans
    388. Buehler BA, Rao V, Finnell RH. Biochemical and molecular teratology of fetal hydantoin syndrome. Neurol Clin. 1994 Nov; 12(4):741-8. PMID: 7845340.
      Citations: 5     Fields:    Translation:HumansAnimals
    389. Musselman AC, Bennett GD, Greer KA, Eberwine JH, Finnell RH. Preliminary evidence of phenytoin-induced alterations in embryonic gene expression in a mouse model. Reprod Toxicol. 1994 Sep-Oct; 8(5):383-95. PMID: 7841657.
      Citations: 1     Fields:    Translation:AnimalsCells
    390. Finnell RH, Kerr BM, van Waes M, Steward RL, Levy RH. Protection from phenytoin-induced congenital malformations by coadministration of the antiepileptic drug stiripentol in a mouse model. Epilepsia. 1994 Jan-Feb; 35(1):141-8. PMID: 8112237.
      Citations: 2     Fields:    Translation:Animals
    391. Finnell RH, van Waes M, Musselman A, Kerr BM, Levy RH. Differences in the patterns of phenytoin-induced malformations following stiripentol coadministration in three inbred mouse strains. Reprod Toxicol. 1993 Sep-Oct; 7(5):439-48. PMID: 8274819.
      Citations: 2     Fields:    Translation:Animals
    392. Finnell RH, Van Waes M, Bennett GD, Eberwine JH. Lack of concordance between heat shock proteins and the development of tolerance to teratogen-induced neural tube defects. Dev Genet. 1993; 14(2):137-47. PMID: 8482018.
      Citations:    Fields:    Translation:AnimalsCells
    393. Finnell RH, Buehler BA, Kerr BM, Ager PL, Levy RH. Clinical and experimental studies linking oxidative metabolism to phenytoin-induced teratogenesis. Neurology. 1992 Apr; 42(4 Suppl 5):25-31. PMID: 1574173.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    394. Eberwine J, Yeh H, Miyashiro K, Cao Y, Nair S, Finnell R, Zettel M, Coleman P. Analysis of gene expression in single live neurons. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):3010-4. PMID: 1557406; PMCID: PMC48793.
      Citations: 312     Fields:    Translation:AnimalsCells
    395. Finnell RH, Ager PL, Englen MD, Bennett GD. The heat shock response: potential to screen teratogens. Toxicol Lett. 1992 Jan; 60(1):39-52. PMID: 1539181.
      Citations: 2     Fields:    Translation:AnimalsCells
    396. Eberwine J, Spencer C, Miyashiro K, Mackler S, Finnell R. Complementary DNA synthesis in situ: methods and applications. Methods Enzymol. 1992; 216:80-100. PMID: 1479921.
      Citations: 20     Fields:    Translation:AnimalsCells
    397. Finnell RH, Mohl VK, Englen MD. In vitro analysis of the murine heat shock response: implications for reproductive toxicology. Toxicol Lett. 1991 Nov; 58(3):297-308. PMID: 1957325.
      Citations:    Fields:    Translation:AnimalsCells
    398. Finnell RH. Genetic differences in susceptibility to anticonvulsant drug-induced developmental defects. Pharmacol Toxicol. 1991 Oct; 69(4):223-7. PMID: 1956873.
      Citations: 4     Fields:    Translation:Humans
    399. Finnell RH, Dansky LV. Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 1: Animal studies. Reprod Toxicol. 1991; 5(4):281-99. PMID: 1806138.
      Citations: 5     Fields:    Translation:Animals
    400. Dansky LV, Finnell RH. Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 2: Human studies. Reprod Toxicol. 1991; 5(4):301-35. PMID: 1806139.
      Citations: 17     Fields:    Translation:Animals
    401. Englen MD, Finnell RH. Strain differences in expression of the murine heat shock response: implications for abnormal neural development. Results Probl Cell Differ. 1991; 17:71-82. PMID: 1803425.
      Citations:    Fields:    Translation:AnimalsCells
    402. Buehler BA, Delimont D, van Waes M, Finnell RH. Prenatal prediction of risk of the fetal hydantoin syndrome. N Engl J Med. 1990 May 31; 322(22):1567-72. PMID: 2336087.
      Citations: 30     Fields:    Translation:Humans
    403. Mohl VK, Bennett GD, Finnell RH. Genetic differences in the duration of the lymphocyte heat shock response in mice. Genetics. 1990 Apr; 124(4):949-55. PMID: 2323557; PMCID: PMC1203985.
      Citations: 1     Fields:    Translation:AnimalsCells
    404. Finnell RH, Toloyan S, van Waes M, Kalivas PW. Preliminary evidence for a cocaine-induced embryopathy in mice. Toxicol Appl Pharmacol. 1990 Apr; 103(2):228-37. PMID: 2330587.
      Citations: 1     Fields:    Translation:Animals
    405. Bennett GD, Mohl VK, Finnell RH. Embryonic and maternal heat shock responses to a teratogenic hyperthermic insult. Reprod Toxicol. 1990; 4(2):113-9. PMID: 2136025.
      Citations: 2     Fields:    Translation:AnimalsCells
    406. Finnell RH, Abbott LC, Taylor SM. The fetal hydantoin syndrome: answers from a mouse model. Reprod Toxicol. 1989; 3(2):127-33. PMID: 2520510.
      Citations: 1     Fields:    Translation:Animals
    407. Finnell RH, Bennett GD, Karras SB, Mohl VK. Common hierarchies of susceptibility to the induction of neural tube defects in mouse embryos by valproic acid and its 4-propyl-4-pentenoic acid metabolite. Teratology. 1988 Oct; 38(4):313-20. PMID: 3149038.
      Citations: 14     Fields:    Translation:Animals
    408. Finnell RH, Chernoff GF. Anagyrine-induced congenital defects. J Pediatr. 1988 Feb; 112(2):331. PMID: 3339518.
      Citations:    Fields:    Translation:Humans
    409. Finnell RH, Shields HE, Taylor SM, Chernoff GF. Strain differences in phenobarbital-induced teratogenesis in mice. Teratology. 1987 Apr; 35(2):177-85. PMID: 3603402.
      Citations: 7     Fields:    Translation:Animals
    410. Finnell RH, Shields HE, Chernoff GF. Variable patterns in anticonvulsant drug-induced malformations in mice: comparisons of phenytoin and phenobarbital. Teratog Carcinog Mutagen. 1987; 7(6):541-9. PMID: 2893467.
      Citations: 1     Fields:    Translation:Animals
    411. Taylor SM, Finnell RH. Effect of quinidine and tetrodotoxin on the activation of non-adrenergic nerves in guinea-pig trachealis muscle. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987; 86(1):11-5. PMID: 2881704.
      Citations:    Fields:    Translation:AnimalsCells
    412. Boehnke WH, Chernoff GF, Finnell RH. Investigation of the teratogenic effects of exercise on pregnancy outcome in mice. Teratog Carcinog Mutagen. 1987; 7(4):391-7. PMID: 2888217.
      Citations: 1     Fields:    Translation:Animals
    413. Finnell RH, Baer JF. Congenital defects among the offspring of epileptic fathers: role of the genotype and phenytoin therapy in a mouse model. Epilepsia. 1986 Nov-Dec; 27(6):697-705. PMID: 3780606.
      Citations:    Fields:    Translation:HumansAnimals
    414. Abbott LC, Finnell RH, Chernoff GF, Parish SM, Gay CC. Crooked calf disease: a histological and histochemical examination of eight affected calves. Vet Pathol. 1986 Nov; 23(6):734-40. PMID: 3811138.
      Citations:    Fields:    Translation:Animals
    415. Willow M, Taylor SM, Catterall WA, Finnell RH. Down regulation of sodium channels in nerve terminals of spontaneously epileptic mice. Cell Mol Neurobiol. 1986 Jun; 6(2):213-20. PMID: 2425971.
      Citations: 1     Fields:    Translation:AnimalsCells
    416. Finnell RH, Moon SP, Abbott LC, Golden JA, Chernoff GF. Strain differences in heat-induced neural tube defects in mice. Teratology. 1986 Apr; 33(2):247-52. PMID: 3738820.
      Citations: 18     Fields:    Translation:Animals
    417. Liles WC, Taylor S, Finnell R, Lai H, Nathanson NM. Decreased muscarinic acetylcholine receptor number in the central nervous system of the tottering (tg/tg) mouse. J Neurochem. 1986 Mar; 46(3):977-82. PMID: 3950615.
      Citations: 2     Fields:    Translation:AnimalsCells
    418. Finnell RH, Mohl VK, Bennett GD, Taylor SM. Failure of epoxide formation to influence carbamazepine-induced teratogenesis in a mouse model. Teratog Carcinog Mutagen. 1986; 6(5):393-401. PMID: 2878505.
      Citations: 2     Fields:    Translation:Animals
    419. Taylor SM, Bennett GD, Abbott LC, Finnell RH. Seizure control following administration of anticonvulsant drugs in the quaking mouse. Eur J Pharmacol. 1985 Nov 26; 118(1-2):163-70. PMID: 3936724.
      Citations: 6     Fields:    Translation:Animals
    420. Finnell RH, Chernoff GF. Genetic background: the elusive component in the fetal hydantoin syndrome. Am J Med Genet. 1984 Nov; 19(3):459-62. PMID: 6507492.
      Citations: 2     Fields:    Translation:Humans
    421. Finnell RH, Chernoff GF. Variable patterns of malformation in the mouse fetal hydantoin syndrome. Am J Med Genet. 1984 Nov; 19(3):463-71. PMID: 6507493.
      Citations: 4     Fields:    Translation:Animals
    422. Finnell RH, DiLiberti JH. Hydantoin-induced teratogenesis: are arene oxide intermediates really responsible? Helv Paediatr Acta. 1983 May; 38(2):171-7. PMID: 6135678.
      Citations:    Fields:    Translation:Humans
    423. Finnell RH, Chernoff GF. Mouse fetal hydantoin syndrome: effects of maternal seizures. Epilepsia. 1982 Aug; 23(4):423-9. PMID: 7094908.
      Citations: 1     Fields:    Translation:Animals
    424. Finnell RH. Phenytoin-induced teratogenesis: a mouse model. Science. 1981 Jan 30; 211(4481):483-4. PMID: 7455686.
      Citations: 5     Fields:    Translation:Animals
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