HSIANG-CHIH (SEAN) LU

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
Address6720 BERTNER
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Patel B, Pugazenthi S, English CW, Nitturi V, Pari SS, Mahlokozera T, Leidig WA, Lu HC, Yang A, Roberts K, DeSouza P, McGeehan KP, Mao DD, Sinha N, Ippolito JE, Dahiya S, Petti A, Yano H, Klisch TJ, Harmanci AS, Patel AJ, Kim AH, Patel B, Pugazenthi S, English CW, Nitturi V, Pari SS, Mahlokozera T, Leidig WA, Lu HC, Yang A, Roberts K, DeSouza P, McGeehan KP, Mao DD, Sinha N, Ippolito JE, Dahiya S, Petti A, Yano H, Klisch TJ, Harmanci AS, Patel AJ, Kim AH. NF2 loss-of-function and hypoxia drive radiation resistance in grade 2 meningiomas. J Natl Cancer Inst. 2025 Jun 01; 117(6):1175-1187. PMID: 39886924; PMCID: PMC12145909.
      Citations: 1     Fields:    
    2. El-Dana F, Aldape K, Abdullaev Z, Sheth SA, Mandel J, Lu HC. Low-grade glial/glioneuronal tumor with YAP1::FAM118B fusion: A novel molecular finding. J Neuropathol Exp Neurol. 2025 Apr 01; 84(4):360-362. PMID: 39301650.
      Citations:    Fields:    
    3. Donofrio SG, Brandenburg C, Brown AM, Lin T, Lu HC, Sillitoe RV. Cerebellar Purkinje cell stripe patterns reveal a differential vulnerability and resistance to cell loss during normal aging in mice. bioRxiv. 2025 Feb 02. PMID: 39974902; PMCID: PMC11838208.
      Citations:    
    4. Chen JW, Giridharan N, Kavoussi AA, Van Arsdale D, Hosseingholi Nouri S, Nitturi V, Trudeau T, Mandel JJ, Lu HC, Patel AJ. Isolated calvarial lesion as the initial presentation of metastatic hepatocellular carcinoma: A case report and review of the literature. Surg Neurol Int. 2025; 16:6. PMID: 39926447; PMCID: PMC11799690.
      Citations:    
    5. Harmanci AS, Boudreau B, Lau S, Hosseingholi Nouri S, Mandel JJ, Lu HC, Harmanci AO, Klisch TJ, Levine JM, Patel AJ. Aggressive human MenG C meningiomas have a molecular counterpart in canines. Acta Neuropathol. 2024 02 20; 147(1):42. PMID: 38376654.
      Citations: 1     Fields:    Translation:HumansAnimals
    6. Rasband JM, Alfattal R, Patel AJ, Fuller GN, Perry A, Lu HC. Cavernous sinus hemangioma: Histopathological spectrum of 8 cases. J Neuropathol Exp Neurol. 2023 09 20; 82(10):884-886. PMID: 37487571.
      Citations: 1     Fields:    Translation:Humans
    7. Khan AB, English CW, Chen WC, Athukuri P, Bayley JC, Brandt VL, Shetty A, Hadley CC, Choudhury A, Lu HC, Harmanci AO, Harmanci AS, Magill ST, Raleigh DR, Klisch TJ, Patel AJ. Even heterozygous loss of CDKN2A/B greatly accelerates recurrence in aggressive meningioma. Acta Neuropathol. 2023 04; 145(4):501-503. PMID: 36729132; PMCID: PMC10323927.
      Citations: 4     Fields:    Translation:Humans
    8. McDonald MF, Athukuri P, Anand A, Gopakumar S, Jalali A, Patel AJ, Rao G, Goodman JC, Lu HC, Mandel JJ. Varied histomorphology and clinical outcomes of FGFR3-TACC3 fusion gliomas. Neurosurg Focus. 2022 12; 53(6):E16. PMID: 36455273.
      Citations:    Fields:    Translation:Humans
    9. Ehrlich AM, Larkin MB, English CW, Shetty A, Gupta M, Nouri SH, Lu HC, Mandel JJ, Patel AJ. Protracted course of chemical meningitis following posterior fossa epidermoid cyst excision - A case report. Surg Neurol Int. 2022; 13:544. PMID: 36447893; PMCID: PMC9699842.
      Citations: 1     
    10. Mahapatra L, Lu HC, Mansour M, Byrnes K. Discrepancies Between Clinical and Anatomic Causes of Death in Acute Invasive Fungal Sinusitis: An Institutional Experience at a Tertiary Care Center. Arch Pathol Lab Med. 2022 10 01; 146(10):1281-1285. PMID: 35041753.
      Citations:    Fields:    
    11. Li MH, Liu KW, Li Z, Lu HC, Ye QL, Zhang D, Wang JY, Li YF, Zhong ZM, Liu X, Yu X, Liu DK, Tu XD, Liu B, Hao Y, Liao XY, Jiang YT, Sun WH, Chen J, Chen YQ, Ai Y, Zhai JW, Wu SS, Zhou Z, Hsiao YY, Wu WL, Chen YY, Lin YF, Hsu JL, Li CY, Wang ZW, Zhao X, Zhong WY, Ma XK, Ma L, Huang J, Chen GZ, Huang MZ, Huang L, Peng DH, Luo YB, Zou SQ, Chen SP, Lan S, Tsai WC, Van de Peer Y, Liu ZJ. Genomes of leafy and leafless Platanthera orchids illuminate the evolution of mycoheterotrophy. Nat Plants. 2022 04; 8(4):373-388. PMID: 35449401; PMCID: PMC9023349.
      Citations:    
    12. Yang PH, Tao Y, Luo J, Paturu M, Lu HC, Ramkissoon S, Heusel JW, Leuthardt EC, Chicoine MR, Dowling JL, Dunn GP, Duncavage E, Dahiya S, Chattherjee AR, Kim AH. Multivariate analysis of associations between clinical sequencing and outcome in glioblastoma. Neurooncol Adv. 2022 Jan-Dec; 4(1):vdac002. PMID: 35156038; PMCID: PMC8826782.
      Citations:    
    13. Ai Y, Li Z, Sun WH, Chen J, Zhang D, Ma L, Zhang QH, Chen MK, Zheng QD, Liu JF, Jiang YT, Li BJ, Liu X, Xu XY, Yu X, Zheng Y, Liao XY, Zhou Z, Wang JY, Wang ZW, Xie TX, Ma SH, Zhou J, Ke YJ, Zhou YZ, Lu HC, Liu KW, Yang FX, Zhu GF, Huang L, Peng DH, Chen SP, Lan S, Van de Peer Y, Liu ZJ. Correction: The Cymbidium genome reveals the evolution of unique morphological traits. Hortic Res. 2021 Dec 14; 8(1):264. PMID: 34907207; PMCID: PMC8671566.
      Citations:    
    14. Ai Y, Li Z, Sun WH, Chen J, Zhang D, Ma L, Zhang QH, Chen MK, Zheng QD, Liu JF, Jiang YT, Li BJ, Liu X, Xu XY, Yu X, Zheng Y, Liao XY, Zhou Z, Wang JY, Wang ZW, Xie TX, Ma SH, Zhou J, Ke YJ, Zhou YZ, Lu HC, Liu KW, Yang FX, Zhu GF, Huang L, Peng DH, Chen SP, Lan S, Van de Peer Y, Liu ZJ. The Cymbidium genome reveals the evolution of unique morphological traits. Hortic Res. 2021 Dec 01; 8(1):255. PMID: 34848682; PMCID: PMC8633000.
      Citations:    
    15. Lu HC, Eulo V, Apicelli AJ, Pekmezci M, Tao Y, Luo J, Hirbe AC, Dahiya S. Correction: Aberrant ATRX protein expression is associated with poor overall survival in NF1-MPNST. Oncotarget. 2021 Nov 23; 12(24):2435-2436. PMID: 34853665; PMCID: PMC8629404.
      Citations:    Fields:    
    16. Schaettler MO, Richters MM, Wang AZ, Skidmore ZL, Fisk B, Miller KE, Vickery TL, Kim AH, Chicoine MR, Osbun JW, Leuthardt EC, Dowling JL, Zipfel GJ, Dacey RG, Lu HC, Johanns TM, Griffith OL, Mardis ER, Griffith M, Dunn GP. Characterization of the Genomic and Immunologic Diversity of Malignant Brain Tumors through Multisector Analysis. Cancer Discov. 2022 01; 12(1):154-171. PMID: 34610950; PMCID: PMC9296070.
      Citations: 1     Fields:    Translation:Humans
    17. Lu HC, Byrnes K, Gonz?lez IA. Ground-glass hepatocellular inclusions are associated with polypharmacy. Ann Diagn Pathol. 2021 Jun; 52:151740. PMID: 33836412.
      Citations:    Fields:    Translation:HumansCells
    18. Gonz?lez IA, Lu HC, Alipour Z, Kulkarni SS, Stoll JM, Liss KHH, Dehner LP, He M. Clinicopathologic Characteristics of Centrilobular Injury in Pediatric Liver Transplantation. Liver Transpl. 2021 02; 27(3):416-424. PMID: 33253466; PMCID: PMC10619582.
      Citations:    Fields:    Translation:Humans
    19. Lu HC, Patterson NH, Judd AM, Reyzer ML, Sehn JK. Imaging Mass Spectrometry Is an Accurate Tool in Differentiating Clear Cell Renal Cell Carcinoma and Chromophobe Renal Cell Carcinoma: A Proof-of-concept Study. J Histochem Cytochem. 2020 06; 68(6):403-411. PMID: 32466698.
      Citations: 2     Fields:    Translation:Humans
    20. Xiang B, Wen J, Lu HC, Schmidt RE, Yablonskiy DA, Cross AH. In vivo evolution of biopsy-proven inflammatory demyelination quantified by R2t* mapping. Ann Clin Transl Neurol. 2020 06; 7(6):1055-1060. PMID: 32367692; PMCID: PMC7317639.
      Citations: 2     Fields:    Translation:Humans
    21. Samara A, Nepute J, Lu HC, Perrin RJ, Eldaya RW. Calvarial Langerhans cell histiocytosis in an Adult: Typical imaging findings in an atypical age group. Radiol Case Rep. 2019 Dec; 14(12):1478-1482. PMID: 31641396; PMCID: PMC6796621.
      Citations: 2     
    22. Lu HC, Sninsky J, Yang C, Bishnupuri K, Dieckgraefe B, Cao D, Chatterjee D, Gonz?lez I. Insulinoma-associated protein 1 expression in primary and metastatic neuroendocrine neoplasms of the gastrointestinal and pancreaticobiliary tracts. Histopathology. 2019 Oct; 75(4):568-577. PMID: 31077609.
      Citations: 8     Fields:    Translation:Humans
    23. Lu HC, Ritter JH, Maluf HM, Dehner LP, He M, Gonz?lez I. Clinicopathologic characteristics of de novo nodular regenerative hyperplasia in pediatric liver transplant. Pediatr Transplant. 2019 08; 23(5):e13471. PMID: 31124197.
      Citations:    Fields:    Translation:Humans
    24. Lin AJ, Hui C, Dahiya S, Lu HC, Kim AH, Campian JL, Tsien C, Zipfel GJ, Rich KM, Chicoine M, Huang J. Radiologic Response and Disease Control of Recurrent Intracranial Meningiomas Treated With Reirradiation. Int J Radiat Oncol Biol Phys. 2018 09 01; 102(1):194-203. PMID: 29970312.
      Citations: 8     Fields:    Translation:Humans
    25. Lu HC, Eulo V, Apicelli AJ, Pekmezci M, Tao Y, Luo J, Hirbe AC, Dahiya S. Aberrant ATRX protein expression is associated with poor overall survival in NF1-MPNST. Oncotarget. 2018 May 01; 9(33):23018-23028. PMID: 29796169; PMCID: PMC5955415.
      Citations: 9     Fields:    
    26. Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajic A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism. Neuron. 2018 03 21; 97(6):1235-1243.e5. PMID: 29526553; PMCID: PMC6422678.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    27. Tan Q, Brunetti L, Rousseaux MWC, Lu HC, Wan YW, Revelli JP, Liu Z, Goodell MA, Zoghbi HY. Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1511-E1519. PMID: 29382756; PMCID: PMC5816173.
      Citations: 17     Fields:    Translation:AnimalsCells
    28. Lu HC, Tan Q, Rousseaux MW, Wang W, Kim JY, Richman R, Wan YW, Yeh SY, Patel JM, Liu X, Lin T, Lee Y, Fryer JD, Han J, Chahrour M, Finnell RH, Lei Y, Zurita-Jimenez ME, Ahimaz P, Anyane-Yeboa K, Lehalle D, Jean-Marcais N, Mosca-Boidron AL, Thevenon J, Cousin MA, Bro DE, Lanpher BC, Klee EW, Alexander N, Bainbridge MN, Orr HT, Sillitoe RV, Ljungberg MC, Liu Z, Schaaf CP, Zoghbi HY, Van Maldergem L. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 Apr; 49(4):527-536. PMID: 28288114; PMCID: PMC5374026.
      Citations: 49     Fields:    Translation:HumansAnimals
    29. Tan Q, Yalamanchili HK, Park J, De Maio A, Lu HC, Wan YW, White JJ, Bondar VV, Sayegh LS, Liu X, Gao Y, Sillitoe RV, Orr HT, Liu Z, Zoghbi HY. Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models. Hum Mol Genet. 2016 12 01; 25(23):5083-5093. PMID: 28007900; PMCID: PMC5968355.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    30. Charng WL, Yamamoto S, Jaiswal M, Bayat V, Xiong B, Zhang K, Sandoval H, David G, Gibbs S, Lu HC, Chen K, Giagtzoglou N, Bellen HJ. Drosophila Tempura, a novel protein prenyltransferase a subunit, regulates notch signaling via Rab1 and Rab11. PLoS Biol. 2014 Jan; 12(1):e1001777. PMID: 24492843; PMCID: PMC3904817.
      Citations: 27     Fields:    Translation:AnimalsCells
    31. Park J, Al-Ramahi I, Tan Q, Mollema N, Diaz-Garcia JR, Gallego-Flores T, Lu HC, Lagalwar S, Duvick L, Kang H, Lee Y, Jafar-Nejad P, Sayegh LS, Richman R, Liu X, Gao Y, Shaw CA, Arthur JSC, Orr HT, Westbrook TF, Botas J, Zoghbi HY. RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1. Nature. 2013 Jun 20; 498(7454):325-331. PMID: 23719381; PMCID: PMC4020154.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    32. Kim E, Lu HC, Zoghbi HY, Song JJ. Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua. Genes Dev. 2013 Mar 15; 27(6):590-5. PMID: 23512657; PMCID: PMC3613606.
      Citations: 22     Fields:    Translation:HumansCells
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