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JAKUB TOLAR

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pediatrics
    DivisionPediatrics-Hematology & Oncology

    TitlePresident
    InstitutionBaylor College of Medicine
    DepartmentOffice of the President
    DivisionOffice of the President


    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hsu A, Chen PJ, Li AH, Hemez CF, Gao XD, Terrey M, Nelson C, Selvam V, Cristian A, McElroy AN, Steinbeck BJ, Mahadeshwar GK, Pandey S, Barsdale Z, Chen PZ, Sousa AA, Sakai HA, Silverstein RA, Morad I, Krueger RK, Shen MW, Kleinstiver BP, Lutz CM, Tolar J, Blazar BR, Osborn MJ, Liu DR. Mechanistic machine learning enables interpretable and generalizable prediction of prime editing outcomes. bioRxiv. 2026 Feb 20. PMID: 41757025; PMCID: PMC12934823.
      Citations:    
    2. Ma L, Koehn B, Zaiken M, Hippen KL, Smith K, Allred J, Williams R, Yao K, Fink J, Saha A, Koop B, Payne N, Widelak R, Panoskaltsis-Mortari A, Riddle MJ, Tolar J, Eide C, Xia L, Witty AD, Mehta AK, Denholtz M, Hefazi M, Hani S, Kenderian SS, Miller JS, Molldrem JJ, Kean LS, Valamehr B, Blazar BR. Inflammasome-resistant IPSC-derived myeloid-derived suppressor cells ameliorate xenogeneic graft-versus-host disease. Blood. 2025 Oct 23; 146(17):2047-2062. PMID: 40700578; PMCID: PMC12983010.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. McGrath JA, Tolar J. New gene therapies for dystrophic epidermolysis bullosa: progress, promise and persistent gaps. Br J Dermatol. 2025 Oct 17; 193(5):809-810. PMID: 40799143.
      Citations:    Fields:    
    4. Bui KG, Chang YC, Chiraphapphaiboon W, Wang J, Ebens CL, Bielinsky AK, Tolar J, Nguyen HD. Contribution of HMGB1 to Keratinocyte inflammation in Recessive Dystrophic Epidermolysis Bullosa. bioRxiv. 2025 Aug 11. PMID: 40832291; PMCID: PMC12363857.
      Citations:    
    5. Zaiken MC, Jin S, McDonald-Hyman C, Hartigan C, Sage P, Hippen KL, Koehn BH, Panoskaltsis-Mortari A, Riddle MJ, Eide C, Tolar J, Hill GR, Luznik L, Cutler CS, Ritz J, Kean LS, Tsagaratou A, Rao A, Blazar BR, Zaiken MC, Jin S, McDonald-Hyman CS, Hartigan CR, Sage PT, Hippen KL, Koehn BH, Panoskaltsis-Mortari A, Riddle MJ, Eide CR, Tolar J, Hill GR, Luznik L, Cutler CS, Ritz JR, Kean LS, Tsagaratou A, Rao A, Blazar BR. Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD. Blood. 2025 Jun 12; 145(24):2813-2827. PMID: 39899881; PMCID: PMC12226767.
      Citations: 1     Fields:    Translation:AnimalsCells
    6. Witte IP, Lampe GD, Eitzinger S, Miller SM, Berr?os KN, McElroy AN, King RT, Stringham OG, Gelsinger DR, Vo PLH, Chen AT, Tolar J, Osborn MJ, Sternberg SH, Liu DR. Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase. Science. 2025 May 15; 388(6748):eadt5199. PMID: 40373119; PMCID: PMC12326709.
      Citations:    
    7. Koehn BH, Nowak EC, Skopelja-Gardner S, Saha A, Zaiken MC, Allred J, Peng Y, Davis WL, Le Mercier I, Schwertner N, Molloy MJ, Rothstein J, Carriere C, Riddle MJ, Eide CR, Tolar J, Panoskaltsis-Mortari A, Smith KD, Hippen KL, Kim TK, Noelle RJ, Blazar BR. Targeting cell-surface VISTA expression on allospecific na?ve T cells promotes tolerance. Blood. 2025 Apr 10; 145(15):1687-1700. PMID: 39919264; PMCID: PMC12000654.
      Citations:    
    8. Osborn MJ, Panda S, Reineke TM, Tolar J, Nystr?m A. Progress in skin gene therapy: From the inside and out. Mol Ther. 2025 May 07; 33(5):2065-2081. PMID: 40077969; PMCID: PMC12126782.
      Citations:    
    9. Sawyer K, Miller W, Popp C, Strege C, Eide C, Tolar J. Analysis of readability of the top web searches for pediatric inborn errors of fatty acid metabolism. Mol Genet Metab Rep. 2025 Mar; 42:101195. PMID: 40092583; PMCID: PMC11910249.
      Citations:    
    10. Macaulay ARK, Yang J, Price MA, Forster CL, Riddle MJ, Ebens CL, Albert FW, Giubellino A, McCarthy JB, Tolar J. Chondroitin sulfate proteoglycan 4 increases invasion of recessive dystrophic epidermolysis bullosa-associated cutaneous squamous cell carcinoma by modifying transforming growth factor-? signalling. Br J Dermatol. 2024 12 23; 192(1):104-117. PMID: 39018437; PMCID: PMC11663483.
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    11. Eapen M, Antin JH, Tolar J, Arai S, Horwitz ME, Kou J, Leifer E, McCarty JM, Nakamura R, Pulsipher MA, Rowley SD, Horowitz MM, Deeg HJ. Long-term survival after unrelated donor marrow transplantation for aplastic anaemia after optimized conditioning regimen: a retrospective multicentre cohort study. EClinicalMedicine. 2024 Oct; 76:102819. PMID: 39290639; PMCID: PMC11405822.
      Citations:    
    12. Dimitrov M, Merkle S, Cao Q, Tryon RK, Vercellotti GM, Holtan SG, Kao RL, Srikanthan M, Terezakis SA, Tolar J, Ebens CL. Allogeneic Hematopoietic Cell Transplant For Bone Marrow Failure or Myelodysplastic Syndrome in Dyskeratosis Congenita/Telomere Biology Disorders: Single-Center, Single-Arm, Open-Label Trial of Reduced-Intensity Conditioning Without Radiation. Transplant Cell Ther. 2024 10; 30(10):1005.e1-1005.e17. PMID: 39002862.
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    13. Pandey S, Gao XD, Krasnow NA, McElroy A, Tao YA, Duby JE, Steinbeck BJ, McCreary J, Pierce SE, Tolar J, Meissner TB, Chaikof EL, Osborn MJ, Liu DR. Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing. Nat Biomed Eng. 2025 Jan; 9(1):22-39. PMID: 38858586; PMCID: PMC11754103.
      Citations:    
    14. Saha A, Palchaudhuri R, Lanieri L, Hyzy S, Riddle MJ, Panthera J, Eide CR, Tolar J, Panoskaltsis-Mortari A, Gorfinkel L, Tkachev V, Gerdemann U, Alvarez-Calderon F, Palato ER, MacMillan ML, Wagner JE, Kean LS, Osborn MJ, Kiem HP, Scadden DT, Olson LM, Blazar BR. Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate-conditioned Fanconi anemia mice. Blood. 2024 05 23; 143(21):2201-2216. PMID: 38447038; PMCID: PMC11143525.
      Citations:    
    15. Steinbeck BJ, Gao XD, McElroy AN, Pandey S, Doman JL, Riddle MJ, Xia L, Chen W, Eide CR, Lengert AH, Han SW, Blazar BR, Wandall HH, Dabelsteen S, Liu DR, Tolar J, Osborn MJ. Twin Prime Editing Mediated Exon Skipping/Reinsertion for Restored Collagen VII?Expression in Recessive Dystrophic Epidermolysis Bullosa. J Invest Dermatol. 2024 Dec; 144(12):2764-2777.e9. PMID: 38763174; PMCID: PMC12050016.
      Citations:    
    16. Wang C, Gu C, Popp C, Vashisth P, Mustfa SA, Martella DA, Spiteri C, McLennan S, Sun N, Riddle M, Eide CR, Parsons M, Tolar J, McGrath JA, Chiappini C. Integrating Porous Silicon Nanoneedles within Medical Devices for Nucleic Acid Nanoinjection. ACS Nano. 2024 06 11; 18(23):14938-14953. PMID: 38726598; PMCID: PMC11171749.
      Citations:    
    17. Stone W, Strege C, Miller W, Geurts AM, Grzybowski M, Riddle M, Lees C, Eide C, Keene DR, Tufa SF, Seelig D, McGrath J, Tolar J. Creation and characterization of novel rat model for recessive dystrophic epidermolysis bullosa: Frameshift mutation of the Col7a1 gene leads to severe blistered phenotype. PLoS One. 2024; 19(5):e0302991. PMID: 38722855; PMCID: PMC11081381.
      Citations:    
    18. Popp C, Miller W, Eide C, Tolar J, McGrath JA, Ebens CL. Beyond the Surface: A Narrative Review Examining the Systemic Impacts of Recessive Dystrophic Epidermolysis Bullosa. J Invest Dermatol. 2024 Sep; 144(9):1943-1953. PMID: 38613531.
      Citations:    
    19. Lee CAA, Wu S, Chow YT, Kofman E, Williams V, Riddle M, Eide C, Ebens CL, Frank MH, Tolar J, Hook KP, AlDubayan SH, Frank NY. Accelerated Aging and Microsatellite Instability in Recessive Dystrophic Epidermolysis Bullosa-Associated Cutaneous Squamous Cell Carcinoma. J Invest Dermatol. 2024 Jul; 144(7):1534-1543.e2. PMID: 38272206; PMCID: PMC11267985.
      Citations:    
    20. Dieter K, Niebergall-Roth E, Daniele C, Fluhr S, Frank NY, Ganss C, Kiritsi D, McGrath JA, Tolar J, Frank MH, Kluth MA. Corrigendum to ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa [Cytotherapy 25 (2023) 782-788/1562]. Cytotherapy. 2023 Sep; 25(9):1016. PMID: 37517864; PMCID: PMC10581616.
      Citations:    
    21. Doman JL, Pandey S, Neugebauer ME, An M, Davis JR, Randolph PB, McElroy A, Gao XD, Raguram A, Richter MF, Everette KA, Banskota S, Tian K, Tao YA, Tolar J, Osborn MJ, Liu DR. Phage-assisted evolution and protein engineering yield compact, efficient prime editors. Cell. 2023 08 31; 186(18):3983-4002.e26. PMID: 37657419; PMCID: PMC10482982.
      Citations:    
    22. Feser CJ, Williams JM, Lammers DT, Bingham JR, Eckert MJ, Tolar J, Osborn MJ. Engineering Human Cells Expressing CRISPR/Cas9-Synergistic Activation Mediators for Recombinant Protein Production. Int J Mol Sci. 2023 May 09; 24(10). PMID: 37239814; PMCID: PMC10218281.
      Citations:    
    23. Ramos TL, Bolivar-Wagers S, Jin S, Thangavelu G, Simonetta F, Lin PY, Hirai T, Saha A, Koehn B, Su LL, Picton LK, Baker J, Lohmeyer JK, Riddle M, Eide C, Tolar J, Panoskaltsis-Mortari A, Wagner JE, Garcia KC, Negrin RS, Blazar BR. Prevention of acute GVHD using an orthogonal IL-2/IL-2R? system to selectively expand regulatory T?cells in?vivo. Blood. 2023 03 16; 141(11):1337-1352. PMID: 36564052; PMCID: PMC10082364.
      Citations:    
    24. Dieter K, Niebergall-Roth E, Daniele C, Fluhr S, Frank NY, Ganss C, Kiritsi D, McGrath JA, Tolar J, Frank MH, Kluth MA. ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa. Cytotherapy. 2023 07; 25(7):782-788. PMID: 36868990; PMCID: PMC10257763.
      Citations:    
    25. Neugebauer ME, Hsu A, Arbab M, Krasnow NA, McElroy AN, Pandey S, Doman JL, Huang TP, Raguram A, Banskota S, Newby GA, Tolar J, Osborn MJ, Liu DR. Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity. Nat Biotechnol. 2023 05; 41(5):673-685. PMID: 36357719; PMCID: PMC10188366.
      Citations:    
    26. Miller W, Pruett CLH, Stone W, Eide C, Riddle M, Popp C, Yousefzadeh M, Lees C, Seelig D, Thompson E, Orr H, Niedernhofer L, Tolar J. Accumulation of senescence observed in spinocerebellar ataxia type 7 mouse model. PLoS One. 2022; 17(10):e0275580. PMID: 36251631; PMCID: PMC9576077.
      Citations:    
    27. Sipe CJ, Kluesner MG, Bingea SP, Lahr WS, Andrew AA, Wang M, DeFeo AP, Hinkel TL, Laoharawee K, Wagner JE, MacMillan ML, Vercellotti GM, Tolar J, Osborn MJ, McIvor RS, Webber BR, Moriarity BS. Correction of Fanconi Anemia Mutations Using Digital Genome Engineering. Int J Mol Sci. 2022 Jul 29; 23(15). PMID: 35955545; PMCID: PMC9369391.
      Citations:    
    28. Feser CJ, Lees CJ, Lammers DT, Riddle MJ, Bingham JR, Eckert MJ, Tolar J, Osborn MJ. Engineering CRISPR/Cas9 for Multiplexed Recombinant Coagulation Factor Production. Int J Mol Sci. 2022 May 03; 23(9). PMID: 35563479; PMCID: PMC9100926.
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    29. Riedl JA, Riddle M, Xia L, Eide C, Boull C, Ebens CL, Tolar J. Interrogation of RDEB Epidermal Allografts after BMT Reveals Coexpression of Collagen VII and Keratin 15 with Proinflammatory Immune Cells and Fibroblasts. J Invest Dermatol. 2022 09; 142(9):2424-2434. PMID: 35304249; PMCID: PMC9391265.
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    30. Thompson EL, Pickett-Leonard M, Riddle MJ, Chen W, Albert FW, Tolar J. Genes and compounds that increase type VII collagen expression as potential treatments for dystrophic epidermolysis bullosa. Exp Dermatol. 2022 07; 31(7):1065-1075. PMID: 35243691; PMCID: PMC9318024.
      Citations:    
    31. Berge JM, Macheledt K, Watson S, Dorr H, Pusalavidyasagar S, Kunin-Batson A, Pratt R, Zimmer SL, Tolar J, Termuhlen A. Using a Community-Based Participatory Approach to Address Gender Equity in Academic Medicine: The Center for Women in Medicine and Science at the University of Minnesota. Acad Med. 2022 03 01; 97(3):370-377. PMID: 34469354.
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    32. Braunlin E, Abrahante JE, McElmurry R, Evans M, Smith M, Seelig D, O'Sullivan MG, Tolar J, Whitley CB, McIvor RS. Contribution of the innate and adaptive immune systems to aortic dilation in murine mucopolysaccharidosis type I. Mol Genet Metab. 2022 03; 135(3):193-205. PMID: 35165009; PMCID: PMC9109621.
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    33. Stefanski HE, Xing Y, Nicholls J, Jonart L, Goren E, Taylor PA, Mills AA, Riddle M, McGrath J, Tolar J, Hollander GA, Blazar BR. P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss. PLoS One. 2022; 17(1):e0261770. PMID: 35077450; PMCID: PMC8789144.
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    34. Meyer-Mueller C, Osborn MJ, Tolar J, Boull C, Ebens CL. Revertant Mosaicism in Epidermolysis Bullosa. Biomedicines. 2022 Jan 06; 10(1). PMID: 35052793; PMCID: PMC8773552.
      Citations:    
    35. Kiritsi D, Dieter K, Niebergall-Roth E, Fluhr S, Daniele C, Esterlechner J, Sadeghi S, Ballikaya S, Erdinger L, Schauer F, Gewert S, Laimer M, Bauer JW, Hovnanian A, Zambruno G, El Hachem M, Bourrat E, Papanikolaou M, Petrof G, Kitzm?ller S, Ebens CL, Frank MH, Frank NY, Ganss C, Martinez AE, McGrath JA, Tolar J, Kluth MA. Clinical trial of ABCB5+ mesenchymal stem cells for recessive dystrophic epidermolysis bullosa. JCI Insight. 2021 11 22; 6(22). PMID: 34665781; PMCID: PMC8663784.
      Citations:    
    36. Walton K, Walker K, Riddle M, Koehn BH, Reff J, Sagatys EM, Linden MA, Pidala J, Kim J, Lee MC, Kiluk JV, Hui JYC, Yun SY, Xing Y, Stefanski H, Lawrence HR, Lawrence NJ, Tolar J, Anasetti C, Blazar BR, Sebti SM, Betts BC. Dual JAK2/Aurora kinase A inhibition prevents human skin graft rejection by allo-inactivation and ILC2-mediated tissue repair. Am J Transplant. 2022 03; 22(3):717-730. PMID: 34668635; PMCID: PMC8897228.
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    37. Popp CM, Miller WC, Eide CR, Tolar J. Future applications of 3D bioprinting: A promising technology for treating recessive dystrophic epidermolysis bullosa. Exp Dermatol. 2022 03; 31(3):384-392. PMID: 34699623; PMCID: PMC9295304.
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    38. Knipping F, Newby GA, Eide CR, McElroy AN, Nielsen SC, Smith K, Fang Y, Cornu TI, Costa C, Gutierrez-Guerrero A, Bingea SP, Feser CJ, Steinbeck B, Hippen KL, Blazar BR, McCaffrey A, Mussolino C, Verhoeyen E, Tolar J, Liu DR, Osborn MJ. Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T?cells and hematopoietic stem and progenitor cells using base editing. Mol Ther. 2022 01 05; 30(1):130-144. PMID: 34737067; PMCID: PMC8753564.
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    39. Kramer AC, Astuti Y, Elfstrum A, Lehrke MJ, Tolar J, Blazar BR, Blake AL, Taisto ME, Furcich JW, Nolan EE, Durose WW, Webber BR, Geisness A, Wood DK, Lund TC. An irradiated marrow niche reveals a small noncollagenous protein mediator of homing, dermatopontin. Blood Adv. 2021 09 28; 5(18):3609-3622. PMID: 34448828; PMCID: PMC8945574.
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    40. Riedl J, Popp C, Eide C, Ebens C, Tolar J. Mesenchymal stromal cells in wound healing applications: role of the secretome, targeted delivery and impact on recessive dystrophic epidermolysis bullosa treatment. Cytotherapy. 2021 11; 23(11):961-973. PMID: 34376336; PMCID: PMC8569889.
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    41. Spector LG, Spellman SR, Thyagarajan B, Beckman KB, Hoffmann C, Garbe J, Hahn T, Sucheston-Campbell L, Richardson M, De For TE, Tolar J, Verneris MR. Neither Donor nor Recipient Mitochondrial Haplotypes Are Associated with Unrelated Donor Transplant Outcomes: A Validation Study from the CIBMTR. Transplant Cell Ther. 2021 10; 27(10):836.e1-836.e7. PMID: 34174468; PMCID: PMC8478819.
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    42. Sarver AL, Xie C, Riddle MJ, Forster CL, Wang X, Lu H, Wagner W, Tolar J, Hallstrom TC. Retinoblastoma tumor cell proliferation is negatively associated with an immune gene expression signature and increased immune cells. Lab Invest. 2021 06; 101(6):701-718. PMID: 33658609.
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    43. Riedl J, Pickett-Leonard M, Eide C, Kluth MA, Ganss C, Frank NY, Frank MH, Ebens CL, Tolar J. ABCB5+ dermal mesenchymal stromal cells with favorable skin homing and local immunomodulation for recessive dystrophic epidermolysis bullosa treatment. Stem Cells. 2021 07; 39(7):897-903. PMID: 33609408; PMCID: PMC8278965.
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    44. Twaroski K, Chen W, Pickett-Leonard M, Tolar J. Role of transforming growth factor-?1 in recessive dystrophic epidermolysis bullosa squamous cell carcinoma. Exp Dermatol. 2021 05; 30(5):664-675. PMID: 33595864.
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    45. Osborn MJ, Bhardwaj A, Bingea SP, Knipping F, Feser CJ, Lees CJ, Collins DP, Steer CJ, Blazar BR, Tolar J. CRISPR/Cas9-Based Lateral Flow and Fluorescence Diagnostics. Bioengineering (Basel). 2021 Feb 12; 8(2). PMID: 33673107; PMCID: PMC7918862.
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    46. Van Bruggen C, Punihaole D, Keith AR, Schmitz AJ, Tolar J, Frontiera RR, Reineke TM. Quinine copolymer reporters promote efficient intracellular DNA delivery and illuminate a protein-induced unpackaging mechanism. Proc Natl Acad Sci U S A. 2020 12 29; 117(52):32919-32928. PMID: 33318196; PMCID: PMC7777095.
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    47. Bartos JA, Frascone RJ, Conterato M, Wesley K, Lick C, Sipprell K, Vuljaj N, Burnett A, Peterson BK, Simpson N, Ham K, Bruen C, Woster C, Haley KB, Moore J, Trigger B, Hodgson L, Harkins K, Kosmopoulos M, Aufderheide TP, Tolar J, Yannopoulos D. The Minnesota mobile extracorporeal cardiopulmonary resuscitation consortium for treatment of out-of-hospital refractory ventricular fibrillation: Program description, performance, and outcomes. EClinicalMedicine. 2020 Dec; 29-30:100632. PMID: 33437949; PMCID: PMC7788435.
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    48. Yannopoulos D, Bartos J, Raveendran G, Walser E, Connett J, Murray TA, Collins G, Zhang L, Kalra R, Kosmopoulos M, John R, Shaffer A, Frascone RJ, Wesley K, Conterato M, Biros M, Tolar J, Aufderheide TP. Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial. Lancet. 2020 12 05; 396(10265):1807-1816. PMID: 33197396; PMCID: PMC7856571.
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    49. Le SQ, Nestrasil I, Kan SH, Egeland M, Cooper JD, Elashoff D, Guo R, Tolar J, Yee JK, Dickson PI. Myelin and Lipid Composition of the Corpus Callosum in Mucopolysaccharidosis Type I Mice. Lipids. 2020 11; 55(6):627-637. PMID: 32537944; PMCID: PMC7992919.
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    50. Keith AR, Twaroski K, Ebens CL, Tolar J. Leading edge: emerging drug, cell, and gene therapies for junctional epidermolysis bullosa. Expert Opin Biol Ther. 2020 08; 20(8):911-923. PMID: 32178539; PMCID: PMC7392816.
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    51. Yellamilli A, Ren Y, McElmurry RT, Lambert JP, Gross P, Mohsin S, Houser SR, Elrod JW, Tolar J, Garry DJ, van Berlo JH. Abcg2-expressing side population cells contribute to cardiomyocyte renewal through fusion. FASEB J. 2020 04; 34(4):5642-5657. PMID: 32100368; PMCID: PMC7136149.
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    52. Kang E, Kim YM, Seo GH, Oh A, Yoon HM, Ra YS, Kim EK, Kim H, Heo SH, Kim GH, Osborn MJ, Tolar J, Yoo HW, Lee BH. Phenotype categorization of neurofibromatosis type I and correlation to NF1 mutation types. J Hum Genet. 2020 Jan; 65(2):79-89. PMID: 31776437.
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    53. Chen W, Twaroski K, Eide C, Riddle MJ, Orchard PJ, Tolar J. TCIRG1 Transgenic Rescue of Osteoclast Function Using Induced Pluripotent Stem Cells Derived from Patients with Infantile Malignant Autosomal Recessive Osteopetrosis. J Bone Joint Surg Am. 2019 Nov 06; 101(21):1939-1947. PMID: 31567691.
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    54. Kim YM, Yum MS, Heo SH, Kim T, Jin HK, Bae JS, Seo GH, Oh A, Yoon HM, Lim HT, Kim HW, Ko TS, Lim HS, Osborn MJ, Tolar J, Cozma C, Rolfs A, Zimran A, Lee BH, Yoo HW. Pharmacologic properties of high-dose ambroxol in four patients with Gaucher disease and myoclonic epilepsy. J Med Genet. 2020 02; 57(2):124-131. PMID: 31649052; PMCID: PMC7029246.
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    55. Lund TC, Miller WP, Liao AY, Tolar J, Shanley R, Pasquali M, Sando N, Bigger BW, Polgreen LE, Orchard PJ. Post-transplant laronidase augmentation for children with Hurler syndrome: biochemical outcomes. Sci Rep. 2019 Oct 01; 9(1):14105. PMID: 31575939; PMCID: PMC6773848.
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    56. Polgreen LE, Lund TC, Braunlin E, Tolar J, Miller BS, Fung E, Whitley CB, Eisengart JB, Northrop E, Rudser K, Miller WP, Orchard PJ. Clinical trial of laronidase in Hurler syndrome after hematopoietic cell transplantation. Pediatr Res. 2020 01; 87(1):104-111. PMID: 31434105; PMCID: PMC6960090.
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    57. Osborn MJ, Newby GA, McElroy AN, Knipping F, Nielsen SC, Riddle MJ, Xia L, Chen W, Eide CR, Webber BR, Wandall HH, Dabelsteen S, Blazar BR, Liu DR, Tolar J. Base Editor Correction of COL7A1 in Recessive?Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs. J Invest Dermatol. 2020 02; 140(2):338-347.e5. PMID: 31437443; PMCID: PMC6983342.
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    58. Tryon RK, Tolar J, Preusser SM, Riddle MJ, Keene DR, Bower M, Thyagarajan B, Ebens CL. A homozygous frameshift variant in the KRT5 gene is compatible with life and results in severe recessive epidermolysis bullosa simplex. JAAD Case Rep. 2019 Jul; 5(7):576-579. PMID: 31312705; PMCID: PMC6610641.
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    59. Onoufriadis A, Hsu CK, Eide CR, Nanda A, Orchard GE, Tomita K, Sheriff A, Scott W, Tierney C, Lee JYW, Gomaa NS, Desomchoke R, Lwin SM, Tu WT, Chen LY, Huang HY, Chao SC, Yu-Yun Lee J, Bare Y, Hayday T, Guy AL, Liu L, Lees C, Hirdler T, Lovell P, Xia L, Dayrit JF, Calonje E, Simpson MA, Tolar J, Parsons M, McGrath JA. Semidominant GPNMB Mutations in Amyloidosis Cutis Dyschromica. J Invest Dermatol. 2019 12; 139(12):2550-2554.e9. PMID: 31226264.
      Citations:    
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    61. Matson JP, Dumitru R, Coryell P, Baxley RM, Chen W, Twaroski K, Webber BR, Tolar J, Bielinsky AK, Purvis JE, Cook JG. Correction: Rapid DNA replication origin licensing protects stem cell pluripotency. Elife. 2019 Jun 05; 8. PMID: 31166167; PMCID: PMC6550866.
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    62. Eisengart JB, Pierpont EI, Kaizer AM, Rudser KD, King KE, Pasquali M, Polgreen LE, Dickson PI, Le SQ, Miller WP, Tolar J, Orchard PJ, Lund TC. Intrathecal enzyme replacement for Hurler syndrome: biomarker association with neurocognitive outcomes. Genet Med. 2019 11; 21(11):2552-2560. PMID: 31019279; PMCID: PMC6831510.
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    63. Boyle WS, Chen W, Rodriguez A, Linn S, Tolar J, Lozano K, Reineke TM. Ternary Composite Nanofibers Containing Chondroitin Sulfate Scavenge Inflammatory Chemokines from Solution and Prohibit Squamous Cell Carcinoma Migration. ACS Appl Bio Mater. 2019 Feb 18; 2(2):619-624. PMID: 35016300.
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    64. Boyle WS, Twaroski K, Woska EC, Tolar J, Reineke TM. Molecular Additives Significantly Enhance Glycopolymer-Mediated Transfection of Large Plasmids and Functional CRISPR-Cas9 Transcription Activation Ex Vivo in Primary Human Fibroblasts and Induced Pluripotent Stem Cells. Bioconjug Chem. 2019 02 20; 30(2):418-431. PMID: 30525482.
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    65. Xing Y, Smith MJ, Goetz CA, McElmurry RT, Parker SL, Min D, Hollander GA, Weinberg KI, Tolar J, Stefanski HE, Blazar BR. Thymic Epithelial Cell Support of Thymopoiesis Does Not Require Klotho. J Immunol. 2018 12 01; 201(11):3320-3328. PMID: 30373854; PMCID: PMC6275142.
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    66. Jung JP, Lin WH, Riddle MJ, Tolar J, Ogle BM. A 3D in vitro model of the dermoepidermal junction amenable to mechanical testing. J Biomed Mater Res A. 2018 12; 106(12):3231-3238. PMID: 30208260; PMCID: PMC6283247.
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    67. Fioredda F, Iacobelli S, Korthof ET, Knol C, van Biezen A, Bresters D, Veys P, Yoshimi A, Fagioli F, Mats B, Zecca M, Faraci M, Miano M, Arcuri L, Maschan M, O'Brien T, Diaz MA, Sevilla J, Smith O, Peffault de Latour R, de la Fuente J, Or R, Van Lint MT, Tolar J, Aljurf M, Fisher A, Skorobogatova EV, Diaz de Heredia C, Risitano A, Dalle JH, Sedl?cek P, Ghavamzadeh A, Dufour C. Outcome of haematopoietic stem cell transplantation in dyskeratosis congenita. Br J Haematol. 2018 10; 183(1):110-118. PMID: 29984823.
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    68. Tolar J, Bauer JW, Kaplan DH, Leachman SA, McGrath JA, Paller AS, Griffith-Bauer KA, Stemwedel CE, Kulesz-Martin MF. Montagna Symposium 2017-Precision Dermatology: Next Generation Prevention, Diagnosis, and Treatment. J Invest Dermatol. 2018 06; 138(6):1243-1248. PMID: 29550416; PMCID: PMC5970097.
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    69. Zhu Z, Guo SZ, Hirdler T, Eide C, Fan X, Tolar J, McAlpine MC. 3D Printed Functional and Biological Materials on Moving Freeform Surfaces. Adv Mater. 2018 Jun; 30(23):e1707495. PMID: 29691902; PMCID: PMC6310159.
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    70. Zhang H, Lee CAA, Li Z, Garbe JR, Eide CR, Petegrosso R, Kuang R, Tolar J. A multitask clustering approach for single-cell RNA-seq analysis in Recessive Dystrophic Epidermolysis Bullosa. PLoS Comput Biol. 2018 04; 14(4):e1006053. PMID: 29630593; PMCID: PMC5908193.
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    71. Pennell CA, Barnum JL, McDonald-Hyman CS, Panoskaltsis-Mortari A, Riddle MJ, Xiong Z, Loschi M, Thangavelu G, Campbell HM, Storlie MD, Refaeli Y, Furlan SN, Jensen MC, Kean LS, Miller JS, Tolar J, Osborn MJ, Blazar BR. Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice. Mol Ther. 2018 06 06; 26(6):1423-1434. PMID: 29735365; PMCID: PMC5986973.
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    72. Lee CAA, Seo HS, Armien AG, Bates FS, Tolar J, Azarin SM. Modeling and rescue of defective blood-brain barrier function of induced brain microvascular endothelial cells from childhood cerebral adrenoleukodystrophy patients. Fluids Barriers CNS. 2018 Apr 04; 15(1):9. PMID: 29615068; PMCID: PMC5883398.
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    73. Osborn MJ, Lees CJ, McElroy AN, Merkel SC, Eide CR, Mathews W, Feser CJ, Tschann M, McElmury RT, Webber BR, Kim CJ, Blazar BR, Tolar J. CRISPR/Cas9-Based Cellular Engineering for Targeted Gene Overexpression. Int J Mol Sci. 2018 Mar 22; 19(4). PMID: 29565806; PMCID: PMC5979553.
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    74. Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajic A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism. Neuron. 2018 03 21; 97(6):1235-1243.e5. PMID: 29526553; PMCID: PMC6422678.
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    75. Tolar J. Regenerative Solutions for Inherited Diseases. Clin Pharmacol Ther. 2018 05; 103(5):763-766. PMID: 29380353; PMCID: PMC9309030.
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    76. Yoon DH, Osborn MJ, Tolar J, Kim CJ. Incorporation of Immune Checkpoint Blockade into Chimeric Antigen Receptor T Cells (CAR-Ts): Combination or Built-In CAR-T. Int J Mol Sci. 2018 Jan 24; 19(2). PMID: 29364163; PMCID: PMC5855562.
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    77. Du J, Flynn R, Paz K, Ren HG, Ogata Y, Zhang Q, Gafken PR, Storer BE, Roy NH, Burkhardt JK, Mathews W, Tolar J, Lee SJ, Blazar BR, Paczesny S. Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients. Blood. 2018 04 12; 131(15):1743-1754. PMID: 29348127; PMCID: PMC5897867.
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    78. Matson JP, Dumitru R, Coryell P, Baxley RM, Chen W, Twaroski K, Webber BR, Tolar J, Bielinsky AK, Purvis JE, Cook JG. Rapid DNA replication origin licensing protects stem cell pluripotency. Elife. 2017 11 17; 6. PMID: 29148972; PMCID: PMC5720591.
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    79. Vanden Oever M, Twaroski K, Osborn MJ, Wagner JE, Tolar J. Inside out: regenerative medicine for recessive dystrophic epidermolysis bullosa. Pediatr Res. 2018 01; 83(1-2):318-324. PMID: 29593249.
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    80. Hinderer C, Katz N, Louboutin JP, Bell P, Tolar J, Orchard PJ, Lund TC, Nayal M, Weng L, Mesaros C, de Souza CFM, Dalla Corte A, Giugliani R, Wilson JM. Abnormal polyamine metabolism is unique to the neuropathic forms of MPS: potential for biomarker development and insight into pathogenesis. Hum Mol Genet. 2017 10 01; 26(19):3837-3849. PMID: 28934395; PMCID: PMC5886077.
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    81. Webber BR, O'Connor KT, McElmurry RT, Durgin EN, Eide CR, Lees CJ, Riddle MJ, Mathews WE, Frank NY, Kluth MA, Ganss C, Moriarity BS, Frank MH, Osborn MJ, Tolar J. Rapid generation of Col7a1-/- mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells. Lab Invest. 2017 10; 97(10):1218-1224. PMID: 28892093; PMCID: PMC5623156.
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    82. Ivaturi V, Dvorak CC, Chan D, Liu T, Cowan MJ, Wahlstrom J, Stricherz M, Jennissen C, Orchard PJ, Tolar J, Pai SY, Huang L, Aweeka F, Long-Boyle J. Pharmacokinetics and Model-Based Dosing to Optimize Fludarabine Therapy in Pediatric Hematopoietic Cell Transplant Recipients. Biol Blood Marrow Transplant. 2017 Oct; 23(10):1701-1713. PMID: 28684371; PMCID: PMC6108324.
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    83. Ward E, Twaroski K, Tolar J. Feeder-Free Derivation of Naive Human Pluripotent Stem Cells. Stem Cells Dev. 2017 08 01; 26(15):1087-1089. PMID: 28537496; PMCID: PMC5563919.
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    84. Magli A, Incitti T, Kiley J, Swanson SA, Darabi R, Rinaldi F, Selvaraj S, Yamamoto A, Tolar J, Yuan C, Stewart R, Thomson JA, Perlingeiro RCR. PAX7 Targets, CD54, Integrin a9?1, and SDC2, Allow Isolation of Human ESC/iPSC-Derived Myogenic Progenitors. Cell Rep. 2017 06 27; 19(13):2867-2877. PMID: 28658631; PMCID: PMC5528177.
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    85. Skvarova Kramarzova K, Osborn MJ, Webber BR, DeFeo AP, McElroy AN, Kim CJ, Tolar J. CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells. Int J Mol Sci. 2017 Jun 14; 18(6). PMID: 28613254; PMCID: PMC5486091.
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    86. Dietz AC, Savage SA, Vlachos A, Mehta PA, Bresters D, Tolar J, Bonfim C, Dalle JH, de la Fuente J, Skinner R, Boulad F, Duncan CN, Baker KS, Pulsipher MA, Lipton JM, Wagner JE, Alter BP. Late Effects Screening Guidelines after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement From the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects After Pediatric HCT. Biol Blood Marrow Transplant. 2017 Sep; 23(9):1422-1428. PMID: 28533057; PMCID: PMC5565711.
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    87. Smith MJ, Reichenbach DK, Parker SL, Riddle MJ, Mitchell J, Osum KC, Mohtashami M, Stefanski HE, Fife BT, Bhandoola A, Hogquist KA, Holl?nder GA, Z??iga-Pfl?cker JC, Tolar J, Blazar BR. T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction. JCI Insight. 2017 May 18; 2(10). PMID: 28515359; PMCID: PMC5436538.
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    88. Knipping F, Osborn MJ, Petri K, Tolar J, Glimm H, von Kalle C, Schmidt M, Gabriel R. Genome-wide Specificity of Highly Efficient TALENs and CRISPR/Cas9 for T Cell Receptor Modification. Mol Ther Methods Clin Dev. 2017 Mar 17; 4:213-224. PMID: 28345006; PMCID: PMC5363317.
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    89. Lee JYW, Hsu CK, Michael M, Nanda A, Liu L, McMillan JR, Pourreyron C, Takeichi T, Tolar J, Reid E, Hayday T, Blumen SC, Abu-Mouch S, Straussberg R, Basel-Vanagaite L, Barhum Y, Zouabi Y, Al-Ajmi H, Huang HY, Lin TC, Akiyama M, Lee JYY, McLean WHI, Simpson MA, Parsons M, McGrath JA. Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23. Am J Hum Genet. 2017 Feb 02; 100(2):364-370. PMID: 28157540; PMCID: PMC5294675.
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    90. Kramer AC, Weber J, Zhang Y, Tolar J, Gibbens YY, Shevik M, Lund TC. TP53 Modulates Oxidative Stress in Gata1+ Erythroid Cells. Stem Cell Reports. 2017 02 14; 8(2):360-372. PMID: 28132886; PMCID: PMC5312256.
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    91. Dietz AC, Mehta PA, Vlachos A, Savage SA, Bresters D, Tolar J, Boulad F, Dalle JH, Bonfim C, de la Fuente J, Duncan CN, Baker KS, Pulsipher MA, Lipton JM, Wagner JE, Alter BP. Current Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2017 May; 23(5):726-735. PMID: 28115275; PMCID: PMC5423755.
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    92. Astuti Y, Kramer AC, Blake AL, Blazar BR, Tolar J, Taisto ME, Lund TC. A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing. Stem Cell Reports. 2017 01 10; 8(1):177-190. PMID: 28041876; PMCID: PMC5233450.
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    93. Webber BR, Osborn MJ, McElroy AN, Twaroski K, Lonetree CL, DeFeo AP, Xia L, Eide C, Lees CJ, McElmurry RT, Riddle MJ, Kim CJ, Patel DD, Blazar BR, Tolar J. CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa. NPJ Regen Med. 2016; 1. PMID: 28250968; PMCID: PMC5328670.
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    94. Hippen KL, Watkins B, Tkachev V, Lemire AM, Lehnen C, Riddle MJ, Singh K, Panoskaltsis-Mortari A, Vanhove B, Tolar J, Kean LS, Blazar BR. Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease. Transplantation. 2016 Dec; 100(12):2630-2639. PMID: 27861291; PMCID: PMC5175408.
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    95. Osborn MJ, Webber BR, McElmurry RT, Rudser KD, DeFeo AP, Muradian M, Petryk A, Hallgrimsson B, Blazar BR, Tolar J, Braunlin EA. Angiotensin receptor blockade mediated amelioration of mucopolysaccharidosis type I cardiac and craniofacial pathology. J Inherit Metab Dis. 2017 03; 40(2):281-289. PMID: 27743312; PMCID: PMC5335863.
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    96. Osborn M, Lonetree CL, Webber BR, Patel D, Dunmire S, McElroy AN, DeFeo AP, MacMillan ML, Wagner J, Balzar BR, Tolar J. CRISPR/Cas9 Targeted Gene Editing and Cellular Engineering in Fanconi Anemia. Stem Cells Dev. 2016 10; 25(20):1591-1603. PMID: 27538887; PMCID: PMC5035838.
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    97. Vanden Oever M, Muldoon D, Mathews W, McElmurry R, Tolar J. miR-29 Regulates Type VII Collagen in Recessive Dystrophic Epidermolysis Bullosa. J Invest Dermatol. 2016 10; 136(10):2013-2021. PMID: 27328306; PMCID: PMC5341382.
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    98. Yuan C, Bothun ED, Hardten DR, Tolar J, McLoon LK. A novel explanation of corneal clouding in a bone marrow transplant-treated patient with Hurler syndrome. Exp Eye Res. 2016 07; 148:83-89. PMID: 27235795; PMCID: PMC5144536.
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    99. Lindborg BA, Brekke JH, Vegoe AL, Ulrich CB, Haider KT, Subramaniam S, Venhuizen SL, Eide CR, Orchard PJ, Chen W, Wang Q, Pelaez F, Scott CM, Kokkoli E, Keirstead SA, Dutton JR, Tolar J, O'Brien TD. Rapid Induction of Cerebral Organoids From Human Induced Pluripotent Stem Cells Using a Chemically Defined Hydrogel and Defined Cell Culture Medium. Stem Cells Transl Med. 2016 Jul; 5(7):970-9. PMID: 27177577; PMCID: PMC4922855.
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    100. Agrawal P, Ingle NP, Boyle WS, Ward E, Tolar J, Dorfman KD, Reineke TM. Fast, Efficient, and Gentle Transfection of Human Adherent Cells in Suspension. ACS Appl Mater Interfaces. 2016 Apr 13; 8(14):8870-4. PMID: 27035392.
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    101. Tolarov? M, McGrath JA, Tolar J. Venturing into the New Science of?Nucleases. J Invest Dermatol. 2016 Apr; 136(4):742-745. PMID: 27012560; PMCID: PMC5320895.
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    102. Boull CL, Hylwa SA, Sajic D, Wagner JE, Tolar J, Hook KP. Toxic Epidermal Necrolysis in Recessive Dystrophic Epidermolysis Bullosa following Bone Marrow Transplantation. J Pediatr. 2016 Jun; 173:242-4. PMID: 26976809; PMCID: PMC5322426.
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    103. Vallera DA, Felices M, McElmurry R, McCullar V, Zhou X, Schmohl JU, Zhang B, Lenvik AJ, Panoskaltsis-Mortari A, Verneris MR, Tolar J, Cooley S, Weisdorf DJ, Blazar BR, Miller JS. IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function. Clin Cancer Res. 2016 07 15; 22(14):3440-50. PMID: 26847056; PMCID: PMC4947440.
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    104. Ghosh A, Miller W, Orchard PJ, Jones SA, Mercer J, Church HJ, Tylee K, Lund T, Bigger BW, Tolar J, Wynn RF. Enzyme replacement therapy prior to haematopoietic stem cell transplantation in Mucopolysaccharidosis Type I: 10 year combined experience of 2 centres. Mol Genet Metab. 2016 Mar; 117(3):373-7. PMID: 26832957; PMCID: PMC5177791.
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    105. Wagner JE, Brunstein CG, Boitano AE, DeFor TE, McKenna D, Sumstad D, Blazar BR, Tolar J, Le C, Jones J, Cooke MP, Bleul CC. Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft. Cell Stem Cell. 2016 Jan 07; 18(1):144-55. PMID: 26669897; PMCID: PMC4881386.
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    106. Osborn MJ, Webber BR, Knipping F, Lonetree CL, Tennis N, DeFeo AP, McElroy AN, Starker CG, Lee C, Merkel S, Lund TC, Kelly-Spratt KS, Jensen MC, Voytas DF, von Kalle C, Schmidt M, Gabriel R, Hippen KL, Miller JS, Scharenberg AM, Tolar J, Blazar BR. Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases. Mol Ther. 2016 Mar; 24(3):570-81. PMID: 26502778; PMCID: PMC4786913.
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    107. Kitajima K, Nakajima M, Kanokoda M, Kyba M, Dandapat A, Tolar J, Saito MK, Toyoda M, Umezawa A, Hara T. GSK3? inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells. Exp Hematol. 2016 Jan; 44(1):68-74.e1-10. PMID: 26477526; PMCID: PMC5160023.
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    108. Poynter JN, Bestrashniy JR, Silverstein KA, Hooten AJ, Lees C, Ross JA, Tolar J. Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology. BMC Cancer. 2015 Oct 23; 15:769. PMID: 26497383; PMCID: PMC4619074.
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    109. Lund TC, Liegel J, Bejanyan N, Orchard PJ, Cao Q, Tolar J, Brunstein C, Wagner JE, Verneris MR, Weisdorf D. Second allogeneic hematopoietic cell transplantation for graft failure: poor outcomes for neutropenic graft failure. Am J Hematol. 2015 Oct; 90(10):892-6. PMID: 26149534; PMCID: PMC4579006.
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    110. Watt SA, Dayal JH, Wright S, Riddle M, Pourreyron C, McMillan JR, Kimble RM, Prisco M, Gartner U, Warbrick E, McLean WH, Leigh IM, McGrath JA, Salas-Alanis JC, Tolar J, South AP. Lysyl Hydroxylase 3 Localizes to Epidermal Basement Membrane and Is Reduced in Patients with Recessive Dystrophic Epidermolysis Bullosa. PLoS One. 2015; 10(9):e0137639. PMID: 26380979; PMCID: PMC4575209.
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    111. Koehn BH, Apostolova P, Haverkamp JM, Miller JS, McCullar V, Tolar J, Munn DH, Murphy WJ, Brickey WJ, Serody JS, Gabrilovich DI, Bronte V, Murray PJ, Ting JP, Zeiser R, Blazar BR. GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. Blood. 2015 Sep 24; 126(13):1621-8. PMID: 26265697; PMCID: PMC4582338.
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    112. Modiano JF, Lindborg BA, McElmurry RT, Lewellen M, Forster CL, Zamora EA, Schaack J, Bellgrau D, O'Brien TD, Tolar J. Mesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment. Cancer Immunol Immunother. 2015 Nov; 64(11):1449-60. PMID: 26250807; PMCID: PMC4618101.
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    113. Tolarova M, Tolar J. From Mesoderm to Mesodermatology: Bone Marrow Mesenchymal Cells Heal Skin Wounds. Mol Ther. 2015 Aug; 23(8):1283-1284. PMID: 26227251; PMCID: PMC4817871.
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    114. Perdoni C, Osborn MJ, Tolar J. Gene editing toward the use of autologous therapies in recessive dystrophic epidermolysis bullosa. Transl Res. 2016 Feb; 168:50-58. PMID: 26073463; PMCID: PMC4662628.
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    115. Petrof G, Lwin SM, Martinez-Queipo M, Abdul-Wahab A, Tso S, Mellerio JE, Slaper-Cortenbach I, Boelens JJ, Tolar J, Veys P, Ofuya M, Peacock JL, Martinez AE, McGrath JA. Potential of Systemic Allogeneic Mesenchymal Stromal Cell Therapy for Children with Recessive Dystrophic Epidermolysis Bullosa. J Invest Dermatol. 2015 Sep; 135(9):2319-2321. PMID: 25905587; PMCID: PMC5696540.
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    116. Webber BR, Tolar J. From marrow to matrix: novel gene and cell therapies for epidermolysis bullosa. Mol Ther. 2015 Jun; 23(6):987-992. PMID: 25803200; PMCID: PMC4817762.
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    117. Nevala-Plagemann C, Lee C, Tolar J. Placenta-based therapies for the treatment of epidermolysis bullosa. Cytotherapy. 2015 Jun; 17(6):786-795. PMID: 25795271; PMCID: PMC4424102.
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    118. Tolar J, McGrath JA. The three-body problem of therapy with induced pluripotent stem cells. Genome Med. 2015; 7(1):15. PMID: 25705260; PMCID: PMC4335559.
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    119. Osborn MJ, Gabriel R, Webber BR, DeFeo AP, McElroy AN, Jarjour J, Starker CG, Wagner JE, Joung JK, Voytas DF, von Kalle C, Schmidt M, Blazar BR, Tolar J. Fanconi anemia gene editing by the CRISPR/Cas9 system. Hum Gene Ther. 2015 Feb; 26(2):114-26. PMID: 25545896; PMCID: PMC4326027.
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    120. Aldenhoven M, Wynn RF, Orchard PJ, O'Meara A, Veys P, Fischer A, Valayannopoulos V, Neven B, Rovelli A, Prasad VK, Tolar J, Allewelt H, Jones SA, Parini R, Renard M, Bordon V, Wulffraat NM, de Koning TJ, Shapiro EG, Kurtzberg J, Boelens JJ. Long-term outcome of Hurler syndrome patients after hematopoietic cell transplantation: an international multicenter study. Blood. 2015 Mar 26; 125(13):2164-72. PMID: 25624320.
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    121. Tolar J, Tolar M. A living band-aid for epidermolysis bullosa. Blood Transfus. 2015 Jan; 13(1):1-2. PMID: 25636127; PMCID: PMC4317083.
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    122. Zhang L, Guo J, Zhang P, Xiong Q, Wu SC, Xia L, Roy SS, Tolar J, O'Connell TD, Kyba M, Liao K, Zhang J. Derivation and high engraftment of patient-specific cardiomyocyte sheet using induced pluripotent stem cells generated from adult cardiac fibroblast. Circ Heart Fail. 2015 Jan; 8(1):156-66. PMID: 25420485; PMCID: PMC4303534.
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    123. Mack MR, Wendelschafer-Crabb G, McAdams BD, Hordinsky MK, Kennedy WR, Tolar J. Peripheral neuro-immune pathology in recessive dystrophic epidermolysis bullosa. J Invest Dermatol. 2015 Apr; 135(4):1193-1197. PMID: 25431850; PMCID: PMC4366323.
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    124. Dickson PI, Tolar J. The individual (single patient) IND for inborn errors of metabolism. Mol Genet Metab. 2015 Sep-Oct; 116(1-2):1-3. PMID: 25456747.
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    125. Ross JA, Tolar J, Spector LG, DeFor T, Lund TC, Weisdorf DJ, Langer E, Hooten AJ, Thyagarajan B, Gleason MK, Wagner JE, Robien K, Verneris MR. An exploratory analysis of mitochondrial haplotypes and allogeneic hematopoietic cell transplantation outcomes. Biol Blood Marrow Transplant. 2015 Jan; 21(1):81-8. PMID: 25300867; PMCID: PMC4272903.
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    126. Tolar J, McGrath JA. Augmentation of cutaneous wound healing by pharmacologic mobilization of endogenous bone marrow stem cells. J Invest Dermatol. 2014 Sep; 134(9):2312-2314. PMID: 25120149.
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    127. Poynter JN, Fonstad R, Tolar J, Spector LG, Ross JA. Incidence of intracranial germ cell tumors by race in the United States, 1992-2010. J Neurooncol. 2014 Nov; 120(2):381-8. PMID: 25086758; PMCID: PMC4206671.
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    128. Miller JS, Rooney CM, Curtsinger J, McElmurry R, McCullar V, Verneris MR, Lapteva N, McKenna D, Wagner JE, Blazar BR, Tolar J. Expansion and homing of adoptively transferred human natural killer cells in immunodeficient mice varies with product preparation and in?vivo cytokine administration: implications for clinical therapy. Biol Blood Marrow Transplant. 2014 Aug; 20(8):1252-7. PMID: 24816582; PMCID: PMC4099265.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    129. Vanden Oever MJ, Tolar J. Advances in understanding and treating dystrophic epidermolysis bullosa. F1000Prime Rep. 2014; 6:35. PMID: 24860657; PMCID: PMC4017907.
      Citations:    
    130. Tolar J, Tolarova S, McGrath JA. On Medawar's 'Actively acquired tolerance of foreign cells'. Exp Dermatol. 2014 Feb; 23(2):97-8. PMID: 24476006.
      Citations:    
    131. Tolar J, McGrath JA, Xia L, Riddle MJ, Lees CJ, Eide C, Keene DR, Liu L, Osborn MJ, Lund TC, Blazar BR, Wagner JE. Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa. J Invest Dermatol. 2014 May; 134(5):1246-1254. PMID: 24317394; PMCID: PMC3989384.
      Citations:    
    132. Tolar J, Wagner JE. Allogeneic blood and bone marrow cells for the treatment of severe epidermolysis bullosa: repair of the extracellular matrix. Lancet. 2013 Oct 05; 382(9899):1214-23. PMID: 24095195; PMCID: PMC3959900.
      Citations:    
    133. Aoyama K, Saha A, Tolar J, Riddle MJ, Veenstra RG, Taylor PA, Blomhoff R, Panoskaltsis-Mortari A, Klebanoff CA, Munn DH, Murphy WJ, Serody JS, Fulton LM, Teshima T, Chandraratna RA, Dmitrovsky E, Guo Y, Noelle RJ, Blazar BR, Soci? G. Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration. Blood. 2013 Sep 19; 122(12):2125-34. PMID: 23814022; PMCID: PMC3778553.
      Citations: 28     Fields:    Translation:AnimalsCells
    134. Aldoss O, Gruenstein DH, Bass JL, Steinberger J, Zhang Y, Defor TE, Tolar J, Verneris MR, Orchard PJ. Pericardial effusion after pediatric hematopoietic cell transplant. Pediatr Transplant. 2013 May; 17(3):294-9. PMID: 23464863.
      Citations:    
    135. Tolar J. Translating genome engineering to better clinical outcomes. Transl Res. 2013 Apr; 161(4):199-204. PMID: 23416084.
      Citations:    
    136. Tolar J, Wagner JE. Management of severe epidermolysis bullosa by haematopoietic transplant: principles, perspectives and pitfalls. Exp Dermatol. 2012 Dec; 21(12):896-900. PMID: 23016552.
      Citations:    
    137. Eisengart JB, Rudser KD, Tolar J, Orchard PJ, Kivisto T, Ziegler RS, Whitley CB, Shapiro EG. Enzyme replacement is associated with better cognitive outcomes after transplant in Hurler syndrome. J Pediatr. 2013 Feb; 162(2):375-80.e1. PMID: 22974573; PMCID: PMC3524404.
      Citations:    
    138. Tolar J, Becker PS, Clapp DW, Hanenberg H, de Heredia CD, Kiem HP, Navarro S, Qasba P, Rio P, Schmidt M, Sevilla J, Verhoeyen E, Thrasher AJ, Bueren J. Gene therapy for Fanconi anemia: one step closer to the clinic. Hum Gene Ther. 2012 Feb; 23(2):141-4. PMID: 22248350; PMCID: PMC3277737.
      Citations:    
    139. Dolan M, Cioc A, Cross NC, Neglia JP, Tolar J. Favorable outcome of allogeneic hematopoietic cell transplantation for 8p11 myeloproliferative syndrome associated with BCR-FGFR1 gene fusion. Pediatr Blood Cancer. 2012 Jul 15; 59(1):194-6. PMID: 22106025.
      Citations:    
    140. Orchard PJ, Lund T, Miller W, Rothman SM, Raymond G, Nascene D, Basso L, Cloyd J, Tolar J. Chitotriosidase as a biomarker of cerebral adrenoleukodystrophy. J Neuroinflammation. 2011 Oct 20; 8:144. PMID: 22014002; PMCID: PMC3236018.
      Citations:    
    141. Lund TC, Glass TJ, Somani A, Nair S, Tolar J, Nyquist M, Patrinostro X, Blazar BR. Zebrafish stromal cells have endothelial properties and support hematopoietic cells. Exp Hematol. 2012 Jan; 40(1):61-70.e1. PMID: 21920471; PMCID: PMC4106246.
      Citations:    
    142. Osborn MJ, DeFeo AP, Blazar BR, Tolar J. Synthetic zinc finger nuclease design and rapid assembly. Hum Gene Ther. 2011 Sep; 22(9):1155-65. PMID: 21663559; PMCID: PMC4076977.
      Citations:    
    143. Greising SM, Call JA, Lund TC, Blazar BR, Tolar J, Lowe DA. Skeletal muscle contractile function and neuromuscular performance in Zmpste24 -/- mice, a murine model of human progeria. Age (Dordr). 2012 Aug; 34(4):805-19. PMID: 21713376; PMCID: PMC3682066.
      Citations:    
    144. Tolar J, Blazar BR, Wagner JE. Concise review: Transplantation of human hematopoietic cells for extracellular matrix protein deficiency in epidermolysis bullosa. Stem Cells. 2011 Jun; 29(6):900-6. PMID: 21557391.
      Citations:    
    145. Glass TJ, Lund TC, Patrinostro X, Tolar J, Bowman TV, Zon LI, Blazar BR. Stromal cell-derived factor-1 and hematopoietic cell homing in an adult zebrafish model of hematopoietic cell transplantation. Blood. 2011 Jul 21; 118(3):766-74. PMID: 21622651; PMCID: PMC3292438.
      Citations:    
    146. Miller WP, Rothman SM, Nascene D, Kivisto T, DeFor TE, Ziegler RS, Eisengart J, Leiser K, Raymond G, Lund TC, Tolar J, Orchard PJ. Outcomes after allogeneic hematopoietic cell transplantation for childhood cerebral adrenoleukodystrophy: the largest single-institution cohort report. Blood. 2011 Aug 18; 118(7):1971-8. PMID: 21586746.
      Citations:    
    147. Tolar J, Villeneuve P, Keating A. Mesenchymal stromal cells for graft-versus-host disease. Hum Gene Ther. 2011 Mar; 22(3):257-62. PMID: 21288086.
      Citations:    
    148. Polgreen LE, Chahla S, Miller W, Rothman S, Tolar J, Kivisto T, Nascene D, Orchard PJ, Petryk A. Early diagnosis of cerebral X-linked adrenoleukodystrophy in boys with Addison's disease improves survival and neurological outcomes. Eur J Pediatr. 2011 Aug; 170(8):1049-54. PMID: 21279382; PMCID: PMC3101278.
      Citations:    
    149. Heinecke KA, Peacock BN, Blazar BR, Tolar J, Seyfried TN. Lipid composition of whole brain and cerebellum in Hurler syndrome (MPS IH) mice. Neurochem Res. 2011 Sep; 36(9):1669-76. PMID: 21253856.
      Citations:    
    150. Tolar J, Xia L, Riddle MJ, Lees CJ, Eide CR, McElmurry RT, Titeux M, Osborn MJ, Lund TC, Hovnanian A, Wagner JE, Blazar BR. Induced pluripotent stem cells from individuals with recessive dystrophic epidermolysis bullosa. J Invest Dermatol. 2011 Apr; 131(4):848-56. PMID: 21124339; PMCID: PMC4151825.
      Citations:    
    151. Osborn MJ, McElmurry RT, Lees CJ, DeFeo AP, Chen ZY, Kay MA, Naldini L, Freeman G, Tolar J, Blazar BR. Minicircle DNA-based gene therapy coupled with immune modulation permits long-term expression of a-L-iduronidase in mice with mucopolysaccharidosis type I. Mol Ther. 2011 Mar; 19(3):450-60. PMID: 21081900; PMCID: PMC3048178.
      Citations:    
    152. Palpant NJ, Bedada FB, Peacock B, Blazar BR, Metzger JM, Tolar J. Cardiac disease in mucopolysaccharidosis type I attributed to catecholaminergic and hemodynamic deficiencies. Am J Physiol Heart Circ Physiol. 2011 Jan; 300(1):H356-65. PMID: 21076027; PMCID: PMC3023247.
      Citations:    
    153. Lund TC, Kobs A, Blazar BR, Tolar J. Mesenchymal stromal cells from donors varying widely in age are of equal cellular fitness after in vitro expansion under hypoxic conditions. Cytotherapy. 2010 Dec; 12(8):971-81. PMID: 20807020; PMCID: PMC3657201.
      Citations:    
    154. Highfill SL, Rodriguez PC, Zhou Q, Goetz CA, Koehn BH, Veenstra R, Taylor PA, Panoskaltsis-Mortari A, Serody JS, Munn DH, Tolar J, Ochoa AC, Blazar BR. Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13. Blood. 2010 Dec 16; 116(25):5738-47. PMID: 20807889; PMCID: PMC3031417.
      Citations:    
    155. Wagner JE, Ishida-Yamamoto A, McGrath JA, Hordinsky M, Keene DR, Woodley DT, Chen M, Riddle MJ, Osborn MJ, Lund T, Dolan M, Blazar BR, Tolar J. Bone marrow transplantation for recessive dystrophic epidermolysis bullosa. N Engl J Med. 2010 Aug 12; 363(7):629-39. PMID: 20818854; PMCID: PMC2967187.
      Citations:    
    156. Braunlin E, Tolar J, Mackey-Bojack S, Masinde T, Krivit W, Schoen FJ. Clear cells in the atrioventricular valves of infants with severe human mucopolysaccharidosis (Hurler syndrome) are activated valvular interstitial cells. Cardiovasc Pathol. 2011 Sep-Oct; 20(5):315-21. PMID: 20619689.
      Citations:    
    157. Zhou Q, Munger ME, Highfill SL, Tolar J, Weigel BJ, Riddle M, Sharpe AH, Vallera DA, Azuma M, Levine BL, June CH, Murphy WJ, Munn DH, Blazar BR. Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia. Blood. 2010 Oct 07; 116(14):2484-93. PMID: 20570856; PMCID: PMC2953885.
      Citations:    
    158. Long-Boyle J, Huang J, Rydholm N, Smith A, Orchard P, Tolar J, Jacobson P. Pharmacokinetics of clofarabine in patients with high-risk inherited metabolic disorders undergoing brain-sparing hematopoietic cell transplantation. J Clin Pharmacol. 2011 May; 51(5):679-86. PMID: 20525919.
      Citations:    
    159. Orchard PJ, Tolar J. Transplant outcomes in leukodystrophies. Semin Hematol. 2010 Jan; 47(1):70-8. PMID: 20109614.
      Citations:    
    160. Lund TC, Glass TJ, Tolar J, Blazar BR. Expression of telomerase and telomere length are unaffected by either age or limb regeneration in Danio rerio. PLoS One. 2009 Nov 06; 4(11):e7688. PMID: 19893630; PMCID: PMC2766636.
      Citations:    
    161. Tolar J, Hippen KL, Blazar BR. Immune regulatory cells in umbilical cord blood: T regulatory cells and mesenchymal stromal cells. Br J Haematol. 2009 Oct; 147(2):200-6. PMID: 19796269; PMCID: PMC3667699.
      Citations:    
    162. Zhou Q, Bucher C, Munger ME, Highfill SL, Tolar J, Munn DH, Levine BL, Riddle M, June CH, Vallera DA, Weigel BJ, Blazar BR. Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia. Blood. 2009 Oct 29; 114(18):3793-802. PMID: 19724059; PMCID: PMC2773484.
      Citations:    
    163. Tolar J, Braunlin E, Riddle M, Peacock B, McElmurry RT, Orchard PJ, Blazar BR. Gender-related dimorphism in aortic insufficiency in murine mucopolysaccharidosis type I. J Heart Valve Dis. 2009 Sep; 18(5):524-9. PMID: 20099693; PMCID: PMC3541017.
      Citations:    
    164. Luscri N, Mauer M, Sarafoglou K, Moran A, Tolar J. Lactic acidosis and hypoglycemia with ALL relapse following engrafted bone marrow transplant. Pediatr Blood Cancer. 2009 Aug; 53(2):223-5. PMID: 19405138.
      Citations:    
    165. Highfill SL, Kelly RM, O'Shaughnessy MJ, Zhou Q, Xia L, Panoskaltsis-Mortari A, Taylor PA, Tolar J, Blazar BR. Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming. Blood. 2009 Jul 16; 114(3):693-701. PMID: 19458354; PMCID: PMC2713464.
      Citations:    
    166. Tolar J, Orchard PJ. alpha-L-iduronidase therapy for mucopolysaccharidosis type I. Biologics. 2008 Dec; 2(4):743-51. PMID: 19707455; PMCID: PMC2727896.
      Citations:    
    167. Tolar J, Ishida-Yamamoto A, Riddle M, McElmurry RT, Osborn M, Xia L, Lund T, Slattery C, Uitto J, Christiano AM, Wagner JE, Blazar BR. Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells. Blood. 2009 Jan 29; 113(5):1167-74. PMID: 18955559; PMCID: PMC2635082.
      Citations:    
    168. Lund TC, Tolar J, Orchard PJ. Granulocyte colony-stimulating factor mobilized CFU-F can be found in the peripheral blood but have limited expansion potential. Haematologica. 2008 Jun; 93(6):908-12. PMID: 18403392.
      Citations:    
    169. Jacobson P, Huang J, Rydholm N, Tran M, Defor T, Tolar J, Orchard PJ. Higher mycophenolate dose requirements in children undergoing hematopoietic cell transplant (HCT). J Clin Pharmacol. 2008 Apr; 48(4):485-94. PMID: 18296555.
      Citations:    
    170. Huang X, Guo H, Kang J, Choi S, Zhou TC, Tammana S, Lees CJ, Li ZZ, Milone M, Levine BL, Tolar J, June CH, Scott McIvor R, Wagner JE, Blazar BR, Zhou X. Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies. Mol Ther. 2008 Mar; 16(3):580-9. PMID: 18227839; PMCID: PMC4539139.
      Citations:    
    171. Orchard PJ, Blazar BR, Wagner J, Charnas L, Krivit W, Tolar J. Hematopoietic cell therapy for metabolic disease. J Pediatr. 2007 Oct; 151(4):340-6. PMID: 17889065.
      Citations:    
    172. Taylor PA, Ehrhardt MJ, Lees CJ, Tolar J, Weigel BJ, Panoskaltsis-Mortari A, Serody JS, Brinkmann V, Blazar BR. Insights into the mechanism of FTY720 and compatibility with regulatory T cells for the inhibition of graft-versus-host disease (GVHD). Blood. 2007 Nov 01; 110(9):3480-8. PMID: 17606761; PMCID: PMC2200903.
      Citations:    
    173. Yun G, Tolar J, Yerich AK, Marsh SG, Robinson J, Noreen H, Blazar BR, Miller JS. A novel method for KIR-ligand typing by pyrosequencing to predict NK cell alloreactivity. Clin Immunol. 2007 Jun; 123(3):272-80. PMID: 17446137; PMCID: PMC1991282.
      Citations:    
    174. Tolar J, Wang X, Braunlin E, McElmurry RT, Nakamura Y, Bell S, Xia L, Zhang J, Hu Q, Panoskaltsis-Mortari A, Zhang J, Blazar BR. The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia. Exp Hematol. 2007 Apr; 35(4):682-90. PMID: 17379078.
      Citations:    
    175. Serafini M, Dylla SJ, Oki M, Heremans Y, Tolar J, Jiang Y, Buckley SM, Pelacho B, Burns TC, Frommer S, Rossi DJ, Bryder D, Panoskaltsis-Mortari A, O'Shaughnessy MJ, Nelson-Holte M, Fine GC, Weissman IL, Blazar BR, Verfaillie CM. Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells. J Exp Med. 2007 Jan 22; 204(1):129-39. PMID: 17227908; PMCID: PMC2118428.
      Citations: 32     Fields:    Translation:AnimalsCells
    176. Brunstein CG, Weisdorf DJ, DeFor T, Barker JN, Tolar J, van Burik JA, Wagner JE. Marked increased risk of Epstein-Barr virus-related complications with the addition of antithymocyte globulin to a nonmyeloablative conditioning prior to unrelated umbilical cord blood transplantation. Blood. 2006 Oct 15; 108(8):2874-80. PMID: 16804113; PMCID: PMC1895580.
      Citations:    
    177. Subramanian IV, Bui Nguyen TM, Truskinovsky AM, Tolar J, Blazar BR, Ramakrishnan S. Adeno-associated virus-mediated delivery of a mutant endostatin in combination with carboplatin treatment inhibits orthotopic growth of ovarian cancer and improves long-term survival. Cancer Res. 2006 Apr 15; 66(8):4319-28. PMID: 16618757.
      Citations:    
    178. Tolar J, O'shaughnessy MJ, Panoskaltsis-Mortari A, McElmurry RT, Bell S, Riddle M, McIvor RS, Yant SR, Kay MA, Krause D, Verfaillie CM, Blazar BR. Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells. Blood. 2006 May 15; 107(10):4182-8. PMID: 16410448; PMCID: PMC1895284.
      Citations:    
    179. Braunlin E, Mackey-Bojack S, Panoskaltsis-Mortari A, Berry JM, McElmurry RT, Riddle M, Sun LY, Clarke LA, Tolar J, Blazar BR. Cardiac functional and histopathologic findings in humans and mice with mucopolysaccharidosis type I: implications for assessment of therapeutic interventions in hurler syndrome. Pediatr Res. 2006 Jan; 59(1):27-32. PMID: 16326988.
      Citations:    
    180. Huang X, Wilber AC, Bao L, Tuong D, Tolar J, Orchard PJ, Levine BL, June CH, McIvor RS, Blazar BR, Zhou X. Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system. Blood. 2006 Jan 15; 107(2):483-91. PMID: 16189271; PMCID: PMC1895607.
      Citations:    
    181. Osborn MJ, Panoskaltsis-Mortari A, McElmurry RT, Bell SK, Vignali DA, Ryan MD, Wilber AC, McIvor RS, Tolar J, Blazar BR. A picornaviral 2A-like sequence-based tricistronic vector allowing for high-level therapeutic gene expression coupled to a dual-reporter system. Mol Ther. 2005 Sep; 12(3):569-74. PMID: 15964244.
      Citations:    
    182. Tolar J, Osborn M, Bell S, McElmurry R, Xia L, Riddle M, Panoskaltsis-Mortari A, Jiang Y, McIvor RS, Contag CH, Yant SR, Kay MA, Verfaillie CM, Blazar BR. Real-time in vivo imaging of stem cells following transgenesis by transposition. Mol Ther. 2005 Jul; 12(1):42-8. PMID: 15963919.
      Citations:    
    183. Tolar J, Teitelbaum SL, Orchard PJ. Osteopetrosis. N Engl J Med. 2004 Dec 30; 351(27):2839-49. PMID: 15625335.
      Citations:    
    184. Tolar J, Neglia JP. Transplacental and other routes of cancer transmission between individuals. J Pediatr Hematol Oncol. 2003 Jun; 25(6):430-4. PMID: 12794519.
      Citations:    
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