"Serpins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
| Descriptor ID |
D015843
|
| MeSH Number(s) |
D12.644.861 D12.776.872 D27.505.519.389.745.800.675
|
| Concept/Terms |
Serpins- Serpins
- Serpin Protease Inhibitors
- Inhibitors, Serpin Protease
- Protease Inhibitors, Serpin
- Serpin Peptidase Inhibitors
- Inhibitors, Serpin Peptidase
- Peptidase Inhibitors, Serpin
|
Below are MeSH descriptors whose meaning is more general than "Serpins".
Below are MeSH descriptors whose meaning is more specific than "Serpins".
This graph shows the total number of publications written about "Serpins" by people in this website by year, and whether "Serpins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 2 | 0 | 2 |
| 2000 | 2 | 0 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 3 | 1 | 4 |
| 2003 | 3 | 1 | 4 |
| 2004 | 5 | 0 | 5 |
| 2005 | 4 | 2 | 6 |
| 2006 | 3 | 1 | 4 |
| 2007 | 1 | 3 | 4 |
| 2008 | 3 | 0 | 3 |
| 2010 | 3 | 0 | 3 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 3 | 0 | 3 |
| 2019 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Serpins" by people in Profiles.
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Overexpression of an Engineered SERPINB9 Enhances Allogeneic T-cell Persistence and Efficacy. Cancer Immunol Res. 2024 Aug 01; 12(8):1108-1122.
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Deep mutational scanning and massively parallel kinetics of plasminogen activator inhibitor-1 functional stability to probe its latency transition. J Biol Chem. 2022 12; 298(12):102608.
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Serum pigment epithelium-derived factor: Relationships with cardiovascular events, renal dysfunction, and mortality in the Veterans Affairs Diabetes Trial (VADT) cohort. J Diabetes Complications. 2019 10; 33(10):107410.
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Squamous cell carcinoma antigen 1 is associated to poor prognosis in esophageal cancer through immune surveillance impairment and reduced chemosensitivity. Cancer Sci. 2019 May; 110(5):1552-1563.
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Insufficient evidence for a role of SERPINF1 in otosclerosis. Mol Genet Genomics. 2019 Aug; 294(4):1001-1006.
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Cloning of six serpin genes and their responses to GCRV infection in grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2019 Mar; 86:93-100.
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Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest. Cell Physiol Biochem. 2018; 49(2):512-529.
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Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol. 2018 12; 136(6):857-872.
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Squamous Cellular Carcinoma Antigen Serum Determination as a Biomarker of Barrett Esophagus and Esophageal Cancer: A Phase III Study. J Clin Gastroenterol. 2018 May/Jun; 52(5):401-406.
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Phosphaplatin Anti-tumor Effect Enhanced by Liposomes Partly via an Up-regulation of PEDF in Breast Cancer. Anticancer Res. 2018 02; 38(2):623-646.