"Thymosin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Thymosin. A family of heat-stable, polypeptide hormones secreted by the thymus gland. Their biological activities include lymphocytopoiesis, restoration of immunological competence and enhancement of expression of T-cell characteristics and function. They have therapeutic potential in patients having primary or secondary immunodeficiency diseases, cancer or diseases related to aging.
| Descriptor ID |
D013947
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| MeSH Number(s) |
D06.472.910.850 D12.644.548.869 D12.776.922
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thymosin".
Below are MeSH descriptors whose meaning is more specific than "Thymosin".
This graph shows the total number of publications written about "Thymosin" by people in this website by year, and whether "Thymosin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 3 | 0 | 3 |
| 2006 | 2 | 0 | 2 |
| 2007 | 3 | 0 | 3 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
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Below are the most recent publications written about "Thymosin" by people in Profiles.
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Suppression of thymosin ?10 increases cell migration and metastasis of cholangiocarcinoma. BMC Cancer. 2013 Sep 23; 13:430.
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Roles and mechanisms of ?-thymosins in cell migration and cancer metastasis: an update. Cancer Invest. 2013 Feb; 31(2):103-10.
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Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):10178-83.
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Advances in thymosin beta10 research: differential expression, molecular mechanisms, and clinical implications in cancer and other conditions. Cancer Invest. 2009 Dec; 27(10):1016-22.
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Thymosin beta-10 is aberrantly expressed in pancreatic cancer and induces JNK activation. Cancer Invest. 2009 Mar; 27(3):251-6.
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Thymosin Beta 4 is overexpressed in human pancreatic cancer cells and stimulates proinflammatory cytokine secretion and JNK activation. Cancer Biol Ther. 2008 Mar; 7(3):419-23.
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Influence of prothymosin-alpha on HIV-1 target cells. Ann N Y Acad Sci. 2007 Sep; 1112:269-85.
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Thymosin-alpha1 modulates dendritic cell differentiation and functional maturation from human peripheral blood CD14+ monocytes. Immunol Lett. 2007 Jun 15; 110(2):110-20.
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Thymosinalpha1 stimulates cell proliferation by activating ERK1/2, JNK, and increasing cytokine secretion in human pancreatic cancer cells. Cancer Lett. 2007 Apr 08; 248(1):58-67.
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Thymosin beta10 inhibits cell migration and capillary-like tube formation of human coronary artery endothelial cells. Cell Motil Cytoskeleton. 2006 Apr; 63(4):222-30.