"Secretin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide hormone of about 27 amino acids from the duodenal mucosa that activates pancreatic secretion and lowers the blood sugar level. (USAN and the USP Dictionary of Drug Names, 1994, p597)
| Descriptor ID |
D012633
|
| MeSH Number(s) |
D06.472.317.800 D06.472.699.810 D12.644.400.705 D12.644.548.810 D12.776.631.650.705
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Secretin".
Below are MeSH descriptors whose meaning is more specific than "Secretin".
This graph shows the total number of publications written about "Secretin" by people in this website by year, and whether "Secretin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Secretin" by people in Profiles.
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Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling. Gut Microbes. 2023 12; 15(2):2256043.
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Membrane translocation process revealed by in situ structures of type II secretion system secretins. Nat Commun. 2023 07 07; 14(1):4025.
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Delayed Processing of Secretin-Induced Pancreas Fluid Influences the Quality and Integrity of Proteins and Nucleic Acids. Pancreas. 2021 01 01; 50(1):17-28.
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Development and functional characterization of extrahepatic cholangiocyte lines from normal rats. Dig Liver Dis. 2015 Nov; 47(11):964-72.
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Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts. Gut. 2013 Jul; 62(7):1024-33.
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Impaired hippocampal synaptic function in secretin deficient mice. Neuroscience. 2008 Jul 17; 154(4):1417-22.
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Secretin receptor-deficient mice exhibit impaired synaptic plasticity and social behavior. Hum Mol Genet. 2006 Nov 01; 15(21):3241-50.
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The human secretin gene: fine structure in 11p15.5 and sequence variation in patients with autism. Genomics. 2002 Aug; 80(2):185-94.
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Targeted ablation of secretin-producing cells in transgenic mice reveals a common differentiation pathway with multiple enteroendocrine cell lineages in the small intestine. Development. 1999 Sep; 126(18):4149-56.
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Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation. J Biol Chem. 1999 Jun 11; 274(24):17033-41.