"Ghrelin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.
| Descriptor ID |
D054439
|
| MeSH Number(s) |
D06.472.699.301 D12.644.548.322
|
| Concept/Terms |
GHRL Protein- GHRL Protein
- Ppghrelin
- Ghrelin-Obestatin Preprohormone
- Ghrelin Obestatin Preprohormone
- Motilin-Related Peptide Precursor
- Motilin Related Peptide Precursor
- Peptide Precursor, Motilin-Related
- Precursor, Motilin-Related Peptide
- PpMTLRP
- Ghrelin Precursor
- Precursor, Ghrelin
Appetite-Regulating Hormone- Appetite-Regulating Hormone
- Appetite Regulating Hormone
- Motilin-Related Peptide
- Motilin Related Peptide
- Gastric MLTRP
|
Below are MeSH descriptors whose meaning is more general than "Ghrelin".
Below are MeSH descriptors whose meaning is more specific than "Ghrelin".
This graph shows the total number of publications written about "Ghrelin" by people in this website by year, and whether "Ghrelin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 5 | 5 |
| 2007 | 3 | 1 | 4 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 2 | 3 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 2 | 3 |
| 2014 | 3 | 0 | 3 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 0 | 2 | 2 |
| 2019 | 4 | 0 | 4 |
| 2020 | 2 | 1 | 3 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Ghrelin" by people in Profiles.
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Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Commun Biol. 2024 May 25; 7(1):632.
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Anamorelin for the Treatment of Cancer Anorexia-Cachexia Syndrome. Curr Oncol Rep. 2024 Jul; 26(7):762-772.
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Trans-pacific multicenter collaborative study of minimally invasive proximal versus total gastrectomy for proximal gastric and gastroesophageal junction cancers. BMC Surg. 2023 Sep 01; 23(1):262.
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Mechanistic Investigation of GHS-R Mediated Glucose-Stimulated Insulin Secretion in Pancreatic Islets. Biomolecules. 2022 03 06; 12(3).
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Ghrelin polymorphism/TRPV1 receptor expression in Egyptian IBS patients. Cytokine. 2022 04; 152:155827.
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Contribution of growth hormone secretagogue receptor (GHSR) signaling in the ventral tegmental area (VTA) to the regulation of social motivation in male mice. Transl Psychiatry. 2021 04 20; 11(1):230.
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Ghrelin reverses ductular reaction and hepatic fibrosis in a rodent model of cholestasis. Sci Rep. 2020 09 29; 10(1):16024.
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Protective Effects of Ghrelin on Fasting-Induced Muscle Atrophy in Aging Mice. J Gerontol A Biol Sci Med Sci. 2020 03 09; 75(4):621-630.
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Paracrine signaling in islet function and survival. J Mol Med (Berl). 2020 04; 98(4):451-467.
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Endocrinopathies and cancer cachexia. Curr Opin Support Palliat Care. 2019 12; 13(4):286-291.